LOCUS       NM_001008507            1235 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus dehydrogenase/reductase 7B (Dhrs7b), mRNA.
ACCESSION   NM_001008507 XM_213317
VERSION     NM_001008507.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Lodhi,I.J., Wei,X., Yin,L., Feng,C., Adak,S., Abou-Ezzi,G.,
            Hsu,F.F., Link,D.C. and Semenkovich,C.F.
  TITLE     Peroxisomal lipid synthesis regulates inflammation by sustaining
            neutrophil membrane phospholipid composition and viability
  JOURNAL   Cell Metab 21 (1), 51-64 (2015)
   PUBMED   25565205
REFERENCE   2  (bases 1 to 1235)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 1235)
  AUTHORS   Keller,B., Meier,M. and Adamski,J.
  TITLE     Comparison of predicted and experimental subcellular localization
            of two putative rat steroid dehydrogenases from the short-chain
            dehydrogenase/reductase protein superfamily
  JOURNAL   Mol Cell Endocrinol 301 (1-2), 43-46 (2009)
   PUBMED   18775470
  REMARK    GeneRIF: The localization studies on rat short-chain
            dehydrogenases/reductases dhrs7b and dhrs8, are shown.
REFERENCE   4  (bases 1 to 1235)
  AUTHORS   Islinger,M., Luers,G.H., Li,K.W., Loos,M. and Volkl,A.
  TITLE     Rat liver peroxisomes after fibrate treatment. A survey using
            quantitative mass spectrometry
  JOURNAL   J Biol Chem 282 (32), 23055-23069 (2007)
   PUBMED   17522052
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC086453.1.
            
            On Dec 16, 2004 this sequence version replaced XM_213317.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC086453.1, EV763060.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1235
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /note="dehydrogenase/reductase 7B"
                     /db_xref="GeneID:287380"
                     /db_xref="RGD:1311243"
     exon            1..31
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..989
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /EC_number="1.1.-.-"
                     /note="SDR family dehydrogenase/reductase member 7B;
                     short-chain dehydrogenase/reductase family 32C member 1;
                     dehydrogenase/reductase (SDR family) member 7B"
                     /codon_start=1
                     /product="dehydrogenase/reductase SDR family member 7B"
                     /protein_id="NP_001008507.1"
                     /db_xref="GeneID:287380"
                     /db_xref="RGD:1311243"
                     /translation="MISPSSRKGMLKERAMDLVTQTTILPLLFGCLGIFSLFRLLQRT
                     RSKAYLRNAVVVVTGATSGLGKECARVFHAAGAKVVLCGRNVKALEEFTRELADSSSS
                     QGQTHQPCVVTFDLADPGAIAPAAAEILQCFGYVDILINNAGISYRGAISDTIVDVDR
                     KVMEINYFGPVALTKALLPSMVERKRGHIVAISSIQGKISIPFRSAYAASKHATQAFF
                     DCLRAEMKDSDIEVTVISPGYIHTNLSVNAVTADGSRYGALDKNTAQGRSAVEVAQDI
                     FDAVGKKKKDVLLTDFLPTMAVYIRTLAPRLFFRIMASRARKERKSKNS"
     exon            32..210
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     exon            211..320
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     exon            321..537
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     exon            538..630
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     exon            631..783
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
     exon            784..1214
                     /gene="Dhrs7b"
                     /gene_synonym="RGD1311243"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttgattgac catgatttct ccgtcctcta ggaagggtat gctcaaggag agggccatgg
       61 acttggtcac ccagacgacc atcctacccc tgctgtttgg ctgcctgggg attttcagcc
      121 tgttccggct gctccagcgg acccgttcaa aagcttacct gaggaatgct gtggtggtag
      181 ttacaggtgc cacctcaggt ctcggcaaag aatgtgcccg agtcttccat gctgcggggg
      241 ctaaagtggt cctctgtgga cgaaatgtga aggctcttga ggagttcacc cgtgaacttg
      301 ctgattcttc ttcttctcag ggacagacac accagccctg cgtggtgacc tttgacctcg
      361 cagatcctgg tgctattgct ccagcagcag ctgagatcct acagtgcttt ggctatgtgg
      421 acatcctcat caataatgct ggcatcagct accgtggtgc cattagtgat accatagtgg
      481 atgtggaccg gaaggtgatg gaaataaact attttggccc tgttgctcta acaaaagcgc
      541 tcctaccctc catggtagaa aggaagagag gccacatcgt cgccatcagc agcatccagg
      601 gcaagatcag cattcctttt cggtcagcat acgcagcgtc caagcatgcg acccaggcat
      661 tctttgactg tctgcgtgca gagatgaaag acagtgacat cgaggtgact gtgataagcc
      721 ctggctacat ccataccaac ctctctgtaa acgctgtcac tgctgatggc tccagatatg
      781 gagctctaga caagaacaca gcccagggcc gaagcgctgt ggaggtggcc caggatatct
      841 ttgatgctgt ggggaagaag aaaaaagatg ttctcttgac tgactttctg ccaaccatgg
      901 ctgtctacat cagaactctg gctcctagac ttttcttcag aatcatggcc tctagggcca
      961 ggaaagagcg aaaatccaag aactcctgat aatgatagag ctgctagctt gggccagcct
     1021 gatcagactg agtaccacac cttcctggac tggaattgca gtgcaagggg tccacagctg
     1081 agacctggtg gagggctgtc ttctgtttgt tccccaggga gtggattagc ccttagggag
     1141 tgaaatatgg agttgtgcgg ggactctaaa agatgcgaaa taaatgactg aacagtgggt
     1201 cagagttcac agtaaaaaaa aaaaaaaaaa aaaaa
//
