LOCUS       NM_001173557            3102 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus D-glutamate cyclase (Dglucy), mRNA; nuclear gene
            for mitochondrial product.
ACCESSION   NM_001173557 XM_001065046 XM_343095
VERSION     NM_001173557.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3102)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 3102)
  AUTHORS   Ariyoshi,M., Katane,M., Hamase,K., Miyoshi,Y., Nakane,M.,
            Hoshino,A., Okawa,Y., Mita,Y., Kaimoto,S., Uchihashi,M., Fukai,K.,
            Ono,K., Tateishi,S., Hato,D., Yamanaka,R., Honda,S., Fushimura,Y.,
            Iwai-Kanai,E., Ishihara,N., Mita,M., Homma,H. and Matoba,S.
  TITLE     D-Glutamate is metabolized in the heart mitochondria
  JOURNAL   Sci Rep 7, 43911 (2017)
   PUBMED   28266638
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On or before May 13, 2010 this sequence version replaced
            XM_343095.3, XM_001065046.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.24906.1,
                                           SRR26643292.26985.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-209               JAXUCZ010000006.1  125785092-125785300
            210-291             JAXUCZ010000006.1  125786798-125786879
            292-418             JAXUCZ010000006.1  125819169-125819295
            419-569             JAXUCZ010000006.1  125824398-125824548
            570-768             JAXUCZ010000006.1  125826141-125826339
            769-919             JAXUCZ010000006.1  125828765-125828915
            920-1042            JAXUCZ010000006.1  125830433-125830555
            1043-1243           JAXUCZ010000006.1  125832864-125833064
            1244-1504           JAXUCZ010000006.1  125838166-125838426
            1505-1604           JAXUCZ010000006.1  125841583-125841682
            1605-1753           JAXUCZ010000006.1  125845640-125845788
            1754-1873           JAXUCZ010000006.1  125848122-125848241
            1874-2025           JAXUCZ010000006.1  125854757-125854908
            2026-3102           JAXUCZ010000006.1  125859420-125860496
FEATURES             Location/Qualifiers
     source          1..3102
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..3102
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /note="D-glutamate cyclase"
                     /db_xref="GeneID:362769"
                     /db_xref="RGD:1311756"
     exon            1..209
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            210..291
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            292..418
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     CDS             319..2175
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /EC_number="4.2.1.48"
                     /note="UPF0317 protein C14orf159 homolog, mitochondrial"
                     /codon_start=1
                     /product="D-glutamate cyclase, mitochondrial"
                     /protein_id="NP_001167028.1"
                     /db_xref="GeneID:362769"
                     /db_xref="RGD:1311756"
                     /translation="MVPFSLLLRSCLPSAIRSLPKAAHIRNISSMTGGLQPASVVVLP
                     RSLAPAFESFCQGNHGPLPLLGQSEPEKTFPQLSAVPDIRTICPQFQKYEFGTCTGIL
                     TSLEEYSEQLKDMVTFIMDCSFSIEEALEQAGIPRRDLTGSGHAGAYKTAVPCATIAG
                     FCCPLVVTMRPVPKDKLERLLLATHSLGGQQGQPIHIGDPELLGIKPLSKPDYGSYVE
                     CRPGDVPVFWPSHLTSLEAVIGCKAPLAFASPPGCTVMIPRDTVSPASRPTPQMVPEV
                     HAISKDPLHYSIVSAPAAQKIRELESTIATDPGNRGIGHLLLKDELLLAALSLSHAHS
                     VLVTTGFPTHFSHEPPEETDGPPGAIALAAFLQALGKEAAMVVDRRALNLHTKIVEDA
                     VKQGVLKTPIPILTYRGGSVEDARAFLCKDGDPKSPRFDHLVAVERAGRAADGNYYNA
                     RKVNIKHLVDPIDDIFLAAQKIPGISSTGVGDGGNELGMGRVKEAVKKHIRNGDVIAC
                     DVEADFAVIAGVSNWGGYALACALYILNSCPVHERYLRRATGPSGEAGEQSWIQALPS
                     VAKEEKMLGILVQNQVRSGVSGIVGMEVDGLPFHGVHAEMIQKLVDVTTVPM"
     exon            419..569
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            570..768
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            769..919
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1042
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1043..1243
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1504
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1505..1604
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1753
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1754..1873
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            1874..2025
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
     exon            2026..3102
                     /gene="Dglucy"
                     /gene_synonym="RGD1311756"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcctggagc tggcccaggc atgtagatca gagtctgagc tggacagaac aagccggtgg
       61 cagtagcagt ggcagcaggc agccccagaa gcccctgtaa gctgaagaaa aggaccttta
      121 tgcctttcag aacgaagttc attctgcgag gctgaggaaa caaaggggag aattgtgtgt
      181 cactctagtc cagacatctc aaaccaacag gcagccagct cactagaagt ccctggctca
      241 ctggaattgg gagcctttga attccttggg ccacacctgt ctctgtactt ggttctctgc
      301 ggctcattct gggatggtat ggtacccttc tcacttctct tgaggtcttg tctcccctct
      361 gccataagga gtctaccgaa ggcagcacac atcagaaaca tatccagcat gactggagga
      421 ctccagccgg ctagtgtggt ggtcctgccc agatccctag caccagcctt tgaaagcttc
      481 tgccagggta accatggtcc tctaccccta ctcggacaaa gtgagccgga gaagacattt
      541 cctcagctga gtgctgttcc agacataagg accatctgtc cacagtttca gaaatacgag
      601 tttggcacct gcactggcat cctgacctca ctggaagagt actcagaaca gctcaaggac
      661 atggtgacct tcatcatgga ctgcagcttc tctatagaag aggccttgga acaggcaggg
      721 atccccagaa gagacctaac aggttccggc catgcaggag catacaagac agcagtaccc
      781 tgtgccacca tcgctggctt ctgctgccct ctggtggtca caatgagacc agttcccaag
      841 gacaagctgg aaaggctgtt gctggccact cactccctgg gaggacagca aggacaaccc
      901 atccacattg gtgacccaga acttctggga atcaagccac tttctaaacc tgactatggg
      961 agttatgtgg agtgtcggcc cggggatgtc ccagtgttct ggccttctca tctgaccagt
     1021 ctggaagcag tcatcggctg caaggccccg ttggctttcg ccagccctcc aggctgcacg
     1081 gtgatgatcc ccagggacac agtgtcccca gccagtcgtc cgactcctca gatggttcca
     1141 gaagtccacg ccatctccaa agaccctttg cactacagca tagtgtcggc ccctgctgct
     1201 caaaagatca gagagctaga gtccacaatt gccacagacc caggtaaccg gggaattggg
     1261 cacctgctac ttaaagatga gttactgctg gcagctctgt cactgtctca cgcgcactcc
     1321 gtactggtca ccactggatt cccgacacat ttcagtcacg agcccccaga agagacggat
     1381 ggcccaccgg gagctatcgc tttagctgcc ttcctacagg ctctggggaa ggaggccgcc
     1441 atggtggtag accggagagc cttgaacttg catacgaaga ttgttgaaga tgccgtgaag
     1501 caaggagttc tcaagacacc aatccccata ttaacttacc gaggaggatc cgtggaagat
     1561 gctcgggcat ttctgtgcaa agatggggac cccaagtctc ctagattcga ccatctggtg
     1621 gccgtagagc gtgcgggaag ggccgcggat ggtaattact acaacgcaag gaaggtgaac
     1681 atcaaacact tagttgaccc catcgacgac attttcctgg ccgcacaaaa gattcctgga
     1741 atctcatcaa ctggcgttgg tgatggaggc aatgagctcg ggatgggcag agtgaaggag
     1801 gccgtgaaga agcacatcag aaatggagat gtcatcgcct gtgatgtgga ggctgacttt
     1861 gccgtcattg ctggtgtttc taactgggga ggctatgccc tggcctgtgc actatacatt
     1921 ctgaactcat gcccagtcca tgagcgttac ctgaggaggg caactggacc ttccggggaa
     1981 gcaggggaac aaagctggat tcaggccctg ccgtctgtcg ctaaggaaga aaaaatgttg
     2041 ggcatcctgg tacagaacca agttcgaagt ggagtctcgg gcatcgtggg catggaagtg
     2101 gatgggttgc ctttccatgg tgtccacgct gagatgatcc agaagctggt ggatgtcacc
     2161 acagtgccca tgtgaccagc ctcgtttgta tgcaaagtcc ctgcccgatg ccagcctttg
     2221 ggtagaggga ttgctctaac tgcccttcat cctggctcct tcaggccacc ctgtggtctg
     2281 cccggagact ctttctgccc ttcccttgag agataattct ggaacagtta acggaagagc
     2341 agacctaggg gaggtggtgg cacgcacctt taatcccagc actcgggagg cagaggcagc
     2401 tggatctctg aattgagtac agcctggtct acagagtgag ttccagggca gccagagcta
     2461 cacaaagaaa tcctatcttt aaaaaaaaaa aagtatcacc atgacctggg ctaattaagg
     2521 aaggacagaa ggatagagcc acacacagag tgttgggttg aaacactggg gcatgtactc
     2581 attaccacca gcaaaacagt tatatctttg caatactttt tttcctaata gtcatacatt
     2641 tactgtttga agagatctcc tacaagatcc ctccagccat cacatcccac agtccctcgc
     2701 ccccattcac cctgatattt cttacacaaa cttcctgtct gcttagtcct acacctagtc
     2761 aaactctctg ccctctttgt ggggaaggat gccatatttg ccagtagagc ccaaaggtga
     2821 gtcagacctc cccagggctc aggcacatga gttcatcctc atttttcaca acctccaaac
     2881 ctacatttct caacaaaatc agaaactgag ccactgacca ggccccatta tactcttagt
     2941 cccgacatca tgatgacatc tcatgtggga ccggagccta ctaagcgttg tttcatgtct
     3001 ttacatgtgt ctggtgtggt tcttcaaggg gccttcgttg tgaaggagca catggtatag
     3061 attttacact ccaataaagc gtaagtgtaa agagaaaagt ct
//
