LOCUS       NM_001399383            2238 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus DET1 partner of COP1 E3 ubiquitin ligase (Det1),
            transcript variant 1, mRNA.
ACCESSION   NM_001399383 XM_006229398
VERSION     NM_001399383.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2238)
  AUTHORS   Jin,J., Arias,E.E., Chen,J., Harper,J.W. and Walter,J.C.
  TITLE     A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2,
            which is required for S phase destruction of the replication factor
            Cdt1
  JOURNAL   Mol Cell 23 (5), 709-721 (2006)
   PUBMED   16949367
REFERENCE   2  (bases 1 to 2238)
  AUTHORS   Wertz,I.E., O'Rourke,K.M., Zhang,Z., Dornan,D., Arnott,D.,
            Deshaies,R.J. and Dixit,V.M.
  TITLE     Human De-etiolated-1 regulates c-Jun by assembling a CUL4A
            ubiquitin ligase
  JOURNAL   Science 303 (5662), 1371-1374 (2004)
   PUBMED   14739464
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 7, 2022 this sequence version replaced XM_006229398.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.1358.1,
                                           SRR26360190.1871497.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676788 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-126               JAXUCZ010000001.1  142175208-142175333 c
            127-1219            JAXUCZ010000001.1  142171300-142172392 c
            1220-1407           JAXUCZ010000001.1  142168168-142168355 c
            1408-1599           JAXUCZ010000001.1  142162564-142162755 c
            1600-2238           JAXUCZ010000001.1  142159120-142159758 c
FEATURES             Location/Qualifiers
     source          1..2238
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..2238
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /note="DET1 partner of COP1 E3 ubiquitin ligase"
                     /db_xref="GeneID:308775"
                     /db_xref="RGD:1309793"
     exon            1..126
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /inference="alignment:Splign:2.1.0"
     exon            127..1219
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..1789
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /note="isoform 1 is encoded by transcript variant 1; DET1
                     homolog; de-etiolated homolog 1; DET1, COP1 ubiquitin
                     ligase partner"
                     /codon_start=1
                     /product="DET1 homolog isoform 1"
                     /protein_id="NP_001386312.1"
                     /db_xref="GeneID:308775"
                     /db_xref="RGD:1309793"
                     /translation="MDHHVSTIKPRRIQNQNVIHRLERRRISSGRAGTHWHQVRVFHQ
                     NVFPNFTVVNVEKPPCFLRKFSPDGRYFIAFSSDQTSLEIYEYQGCQAAEDLLQGYEG
                     EILSNGNDQRSVSIRGRLFERFFVLLHITNVAANGEHLNRECSLFTDDCRCVIVGSAA
                     YLPDEPHPPFYEVYRNSESVTPNPRSPLEDYSLHIIDLHTGRLCDTRTFKCDKVVLSH
                     NQGLYLYKNILAILSVQQQTIHVFQVTPEGTFIDVRTIGRFCYEDDLLTVSAVFPEVQ
                     RDSQTGMANPFRDPFINSLKHRLLVYLWRRAEQDGSAMAKRRFFQYFDQLRQLRMWKM
                     QLLDENHLFIKYTSEDVVTLRVTDPSQASFFVVYNMVTTEVIAVFENTSDELLELFEN
                     FCDLFRNATLHSEVQFPCSASSNNFARQIQRRFKDTIINAKYGGHTEAVRRLLGQLPI
                     SAQSYSGSPYLDLSLFSYDDKWVSVMERPKTCGDHPIRFYARDSGLLKFEIQAGLLGR
                     PINHTVRRLVAFTFHPFEPFAISVQRTNAEYVVNFHMRHCCT"
     exon            1220..1407
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /inference="alignment:Splign:2.1.0"
     exon            1408..1599
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..2238
                     /gene="Det1"
                     /gene_synonym="RGD1309793"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagcaggg gctggtggct gccgacgccg gggtcccgag gcatggcggg ggcggggccg
       61 ggggaggtgt gcaccgagca ggctagggcg acccttgccc tggccccatg agccaggact
      121 cgacagagat gttataatgg atcatcatgt ttccacgatt aaacctcgaa gaatccaaaa
      181 tcaaaacgtc atccaccgct tagagcgccg gcgcatcagt tcaggcaggg cagggaccca
      241 ctggcatcag gtccgagtct tccaccagaa tgtcttcccc aacttcacgg ttgtcaacgt
      301 tgaaaagcct ccttgtttct tgcgtaaatt ctcgcctgac gggcgctact ttattgcttt
      361 ttcgtctgac cagacatctc ttgaaatcta cgagtaccag ggctgtcagg cagcagagga
      421 cctcttgcag ggatatgaag gggagatctt gtccaatggt aatgaccaga ggtcggtcag
      481 catccgaggc cggctctttg aacgtttttt tgtcctgctg cacattacca atgtagcggc
      541 caatggcgag cacttgaacc gggagtgtag cctcttcacg gacgactgcc gctgtgtcat
      601 cgtgggctcc gctgcctacc ttccagacga acctcaccct cctttctatg aggtctatcg
      661 gaacagtgag tcggtgaccc ctaacccacg gtcccctctc gaagactatt ccctccacat
      721 catcgacctt cacactggcc gtttgtgtga cacacgcaca ttcaagtgtg acaaggtggt
      781 cctgtcacac aatcaagggc tgtacctata caagaacatc ctggccatat tgtctgtgca
      841 gcagcagacc attcatgtct tccaggtgac tcctgaaggc acgtttattg acgttcggac
      901 cattggccgc ttctgctacg aggatgacct gctcactgtg tctgccgttt tccccgaggt
      961 gcagcgggac agccagacag gcatggccaa ccctttcagg gaccctttca tcaactcctt
     1021 gaagcaccgg ttgctggttt acctctggcg cagggcagag caagacggta gcgccatggc
     1081 gaagagacgt ttcttccagt actttgacca gctgcggcag ctgcgcatgt ggaagatgca
     1141 gcttctggat gagaaccacc tgttcatcaa gtacaccagc gaggacgtag tgacgctgcg
     1201 ggtcacagac ccatctcagg cctccttctt tgtggtgtac aacatggtga caacagaggt
     1261 gattgccgtc tttgagaaca cgtcagatga acttctggag ctctttgaga acttctgtga
     1321 cctcttccgc aatgccaccc tgcacagtga agtccagttc ccttgctcag cttctagcaa
     1381 caactttgca aggcagattc agcgccggtt caaagacaca attataaatg ccaagtatgg
     1441 agggcacact gaagctgtgc gccgactgct aggccagctc cccatcagtg cccagtctta
     1501 cagtggaagc ccctacctgg atttgtctct cttcagctac gatgacaagt gggtgtcagt
     1561 catggagcga cccaagactt gtggagatca cccgatcagg ttctatgccc gggactctgg
     1621 cttgctgaag tttgagatcc aggcaggctt gctgggccgc cccatcaacc acacggtgcg
     1681 acgcctcgtg gccttcacct ttcacccctt tgagccattt gccatttctg tgcagaggac
     1741 taacgcagag tacgttgtca acttccacat gcgacactgc tgcacctagt caccccgtta
     1801 cgatcatgat cacgccgtcc aggactccgc ccctgcttcg ctcagtggac gttaaagcaa
     1861 aagctgctag ccgcctgctc tcgtcggcat tccacactgg catgcctcac ctactccaga
     1921 gcctgaggag agggtggggg tgcagcctgg tgggactctg ttgtcttcta cccaactgat
     1981 gagctttaaa gtcgtctttt ccccgtggga acacctggtg ttaaatccat tctattttgt
     2041 ttacttcgca tcttctgtct gtggagatag aagcacttac atacaccttt ccccttgata
     2101 tcactcttga gcattacggt gtgaagcctt cagcaggtaa atcatgttta ctcctgagaa
     2161 ttatgtacgc ctttccatcc cctcaacacg cagggctatc tttataagag aaaataaagc
     2221 cttggtattt tcttagga
//
