LOCUS       NM_001025703            1451 bp    mRNA    linear   ROD 12-MAY-2024
DEFINITION  Rattus norvegicus desumoylating isopeptidase 1 (Desi1), mRNA.
ACCESSION   NM_001025703 XM_235506
VERSION     NM_001025703.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Hirayama,S., Sugihara,M., Morito,D., Iemura,S.I., Natsume,T.,
            Murata,S. and Nagata,K.
  TITLE     Nuclear export of ubiquitinated proteins via the UBIN-POST system
  JOURNAL   Proc Natl Acad Sci U S A 115 (18), E4199-E4208 (2018)
   PUBMED   29666234
REFERENCE   2  (bases 1 to 1451)
  AUTHORS   Shin,E.J., Shin,H.M., Nam,E., Kim,W.S., Kim,J.H., Oh,B.H. and
            Yun,Y.
  TITLE     DeSUMOylating isopeptidase: a second class of SUMO protease
  JOURNAL   EMBO Rep 13 (4), 339-346 (2012)
   PUBMED   22370726
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098857.1.
            
            On Jul 22, 2005 this sequence version replaced XM_235506.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098857.1, CK596240.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132296, SAMEA5756307
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1451
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /note="desumoylating isopeptidase 1"
                     /db_xref="GeneID:315160"
                     /db_xref="RGD:1305776"
     exon            1..271
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..690
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /EC_number="3.1.2.22"
                     /note="PPPDE peptidase domain-containing protein 2; family
                     with sequence similarity 152, member B; PPPDE peptidase
                     domain containing 2; S-depalmitoylase DESI1; palmitoyl
                     protein thioesterase DESI1"
                     /codon_start=1
                     /product="desumoylating isopeptidase 1"
                     /protein_id="NP_001020874.1"
                     /db_xref="GeneID:315160"
                     /db_xref="RGD:1305776"
                     /translation="MEPPNLYPVKLYVYDLSKGLARRLSPIMLGKQLEGIWHTSIVVH
                     KDEFFFGSSGISSCTPGGTLLGPPDSVVDVGNTEVTEEIFLEYLSSLGESLFRGEAYN
                     LFEHNCNTFSNEVAQFLTGRKIPSYITDLPSEVLSTPFGQALRPFLDSIQIQPPGGNS
                     VGRPNGQS"
     exon            272..293
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
     exon            294..363
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
     exon            364..473
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
     exon            474..596
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
     exon            597..1417
                     /gene="Desi1"
                     /gene_synonym="DeSI-1; Fam152b; Pppde2; RGD1305776"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtagtcgt tgccggtcgc gggtgtgggg gcgcgagcag cgcagggccg cctttccccc
       61 gccctcaggc cgggcccggg ctcggtcccc cgctccctcc tctccccacc ccggtcgggt
      121 accggaaggt ccaagccgct gccgggtgcc cgagggccat cgtggccgcc gccacgggtc
      181 ctgatggagc cgccgaatct ctatccggtg aagctctacg tgtacgacct gtccaagggc
      241 ctggcccgcc ggctcagccc catcatgctg gggaaacaac tggaaggaat ctggcatacc
      301 tctatagttg tacacaagga tgagttcttc ttcggcagca gcggtatttc cagctgtacc
      361 ccgggaggga cattgcttgg gcccccagac tctgtggttg atgtggggaa tacagaagtc
      421 acagaagaaa tctttctgga atacctgtcc tccctggggg agtctctgtt ccgaggagaa
      481 gcctacaacc tctttgaaca caactgtaac acctttagca atgaagtggc acagttcctg
      541 actgggcgga agatcccttc ttacatcacc gacctgccct cagaagttct ctccacgccc
      601 tttggacaag cacttcggcc cttcttggac tccattcaga tccagcctcc aggagggaac
      661 tctgtaggca gacccaatgg ccaaagctaa caggactgca cgggaccgcc cgcctctcca
      721 cggcttttcc tttttaaaca aaacaaaccc taccagattt ctattttata attttacatc
      781 agagctaacg gggacggctt tttaaatttc ccagggaagg agctcatcag gccgcatgta
      841 gaacaacgct cctgagaaag agaacaaagc catcccttct aatagtatta cactaattta
      901 ttaaggctgt cttgtctgtg agttcacttt tgacgctgtt gcctacacgt cctccacact
      961 gaagagagag ggtgcttttt aaaagagaag caagagtcac agtctgggag aacccgacct
     1021 tggaccctct ttccagagaa cgccgacatt ccacccaggt cgccacgcct gtgggaccca
     1081 ggtgagttct gtactgtcca ttctcctgaa gctgtcaccc tctagccgta aacgaaccaa
     1141 aggacttgga gtacgtgggg ccagctgtag gctcctaact caacctaagt gaactcttta
     1201 accacaagtt tacccctcct cctgagacaa ggccacccgt cacagccgga gcagccagag
     1261 caacaggatc aaaggagact ggcagcaggg gtgaggccag agaaaacagg agaaagccat
     1321 tcatcctcct gtgagtgcca atcctcgatg cccaccccta agctgctctt cctcagcata
     1381 gcttgacctg tcacctttaa taaaggtcta ggctgcaaaa aaaaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa a
//
