LOCUS       NM_001305205            3327 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus DEP domain containing 1 (Depdc1), mRNA.
ACCESSION   NM_001305205 XM_001080406 XM_227798
VERSION     NM_001305205.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3327)
  AUTHORS   Harada,Y., Kanehira,M., Fujisawa,Y., Takata,R., Shuin,T., Miki,T.,
            Fujioka,T., Nakamura,Y. and Katagiri,T.
  TITLE     Cell-permeable peptide DEPDC1-ZNF224 interferes with
            transcriptional repression and oncogenicity in bladder cancer cells
  JOURNAL   Cancer Res 70 (14), 5829-5839 (2010)
   PUBMED   20587513
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Feb 28, 2015 this sequence version replaced
            XM_227798.8, XM_001080406.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments and orthologous data.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.10593.1,
                                           SRR26643295.11752.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               JAXUCZ010000002.1  251343281-251343424
            145-410             JAXUCZ010000002.1  251346187-251346452
            411-567             JAXUCZ010000002.1  251353000-251353156
            568-689             JAXUCZ010000002.1  251354149-251354270
            690-820             JAXUCZ010000002.1  251354667-251354797
            821-868             JAXUCZ010000002.1  251355564-251355611
            869-1009            JAXUCZ010000002.1  251360670-251360810
            1010-1849           JAXUCZ010000002.1  251362358-251363197
            1850-2022           JAXUCZ010000002.1  251363615-251363787
            2023-2199           JAXUCZ010000002.1  251373410-251373586
            2200-2385           JAXUCZ010000002.1  251374778-251374963
            2386-3327           JAXUCZ010000002.1  251375768-251376709
FEATURES             Location/Qualifiers
     source          1..3327
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..3327
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /note="DEP domain containing 1"
                     /db_xref="GeneID:295538"
                     /db_xref="RGD:1306987"
     exon            1..144
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..2526
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /note="DEP domain containing 1a"
                     /codon_start=1
                     /product="DEP domain-containing protein 1A"
                     /protein_id="NP_001292134.1"
                     /db_xref="GeneID:295538"
                     /db_xref="RGD:1306987"
                     /translation="MERQGAPLGPYRATKLWNEVTTSFRVGMPLRKHRQHLKKYSNCF
                     TAVEAVDWLYDLLRSNSNFGPEVTRQQTIQLLRKFLKNHVIEDIKGRWGSENLDDNNQ
                     LFRFPATSPLKTFPQRHTEIKKTSTEYFSKDRDSIFKLRNLSRKTPKKRGLQFSQENT
                     EKINHERITNEDQENVPENKEISQEDVEDVWRYVTMIYLQTILGVPSIEELINPNQVI
                     PQYIMYNMANTSKHGVVILQNKSEDLPHWVLSAMKCLANWPRCNDTNSLTYVGFERDV
                     FKTIADYFLDLPEPLLTFEYYELFVNILVVCGYITVSDKTSGIHKIQDDPRSSQIHDL
                     SNLNSFKSTECLLLSLLSKDKSNEELDSTERLQRSDQGFQERCTKKMQLVNLRNRRAS
                     ANDIMGGSCHNLIGLSNTNALSSNIKPRCSSLEGIIDMPVNSSEKKSSVFYLSVLNIE
                     EHSSEQSLAPVPKQKSLLNLHSEEYAQQPHSVGFKRTSALTIEDQEDVCNGKYTSKQL
                     CRSQSLLLRSSTRQNSSINKPVAEIIMKPNVGQGSTSVQSKLGGSITTINKRLCKSTI
                     ELSENSLPPAASVLTGTQSLLQPHLERVAINALQLCCLLLPPPNRRKLQLLMRMISRM
                     SQNVDLPKLHEEIGTRSLMINTFSRCVLCCAEEVDLDELLASRLVSFLMDHHQEILQV
                     PTYLQAAVEKHLDYIKKGHVKNHGDGLVVPLPTYSYCKQISAKEFDEQKISTSQAAIA
                     ELLENIVRSKSLPLKEKRRKLKQFQKEYPLIYQKRFPTTESEAALFDDKPTIKQPMLN
                     LRNPKLHSLRY"
     exon            145..410
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            411..567
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            568..689
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            690..820
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            821..868
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1009
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1849
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            1850..2022
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2199
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2200..2385
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..3327
                     /gene="Depdc1"
                     /gene_synonym="Depdc1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaatcagcag cgcggcagtt gttccgacac caactccagg ccacagaagt tcctgctaca
       61 gcgctgtttc cgccgcctca gcctggcaat gacagcatgg agcgtcaggg tgctcctctt
      121 ggaccttacc gggccaccaa gctgtggaac gaagtgacca catcttttcg agtaggaatg
      181 cctttaagaa aacatagaca acatttaaaa aaatatagca attgttttac tgcagttgaa
      241 gcagtagatt ggctttatga tctattgaga agtaatagta attttggtcc tgaagttaca
      301 agacaacaga ctattcaact gttgagaaaa tttcttaaga atcatgtgat tgaagatatc
      361 aaaggtagat ggggatcaga aaaccttgat gacaacaatc aactattcag atttcctgca
      421 acttctccac ttaaaacttt tccacaaaga catacagaaa tcaagaaaac cagcacagag
      481 tacttttcca aagacagaga tagtattttt aaattacgaa acttatctcg taaaactcct
      541 aagaagcgtg gactacagtt ctctcaggaa aatacagaaa agataaatca tgaaagaata
      601 accaatgaag atcaagaaaa tgtacctgaa aacaaagaaa taagtcagga ggatgttgaa
      661 gatgtttgga gatacgttac tatgatctac ctgcaaacta tcttaggtgt gccatccata
      721 gaagaactca taaacccaaa ccaagtaatt cctcaataca taatgtacaa catggccaac
      781 acaagtaagc atggagtggt catactacaa aacaaatcag aggatcttcc acactgggta
      841 ttatctgcta tgaagtgcct agcaaattgg ccaagatgta atgacaccaa tagtctaact
      901 tatgttggat ttgaacgtga tgtattcaaa acaattgcag attattttct agatctccct
      961 gaacctctac ttacatttga atattatgaa ttgtttgtga acattttggt tgtttgtggc
     1021 tacatcacag tttcagataa aacaagtggg atacataaaa tccaagatga tccacggtct
     1081 tcacaaatcc atgatttaag caatttgaat tccttcaaat caactgagtg ccttcttctc
     1141 agtctgcttt ccaaagacaa aagcaatgaa gaattggatt ctactgagag actacaaaga
     1201 agtgatcaag gatttcaaga aagatgcacc aagaaaatgc agctagttaa tttaagaaac
     1261 agaagagcta gtgctaatga cataatggga ggaagctgtc ataatttaat aggcttaagt
     1321 aatacaaatg ccctgtcctc taacataaaa ccaaggtgct cttctttgga aggaattata
     1381 gatatgccag tgaattcaag tgaaaagaag tccagtgtct tctacctgtc agttctgaat
     1441 atagaagaac acagtagtga gcagtcatta gcaccggtgc ccaagcagaa atccctactt
     1501 aatcttcact cagaggaata tgctcagcag ccacactctg ttggttttaa aagaacttct
     1561 gctttgacta ttgaagacca agaagacgta tgtaatggaa agtacacgtc aaaacagctt
     1621 tgtagatctc agagtttact tttaagaagt agtacaaggc agaatagttc tatcaataaa
     1681 ccagtggctg aaattataat gaaaccaaat gttggacaag gcagtacaag tgtacaaagt
     1741 aagctcggag ggtctattac cacaatcaat aaaagactgt gcaaaagcac catagaactt
     1801 tcagagaatt ccttacctcc agctgcttct gtgttgactg gcacacaaag tttgctgcag
     1861 cctcacttag agagggttgc catcaatgct ctacagttgt gttgtttgtt acttccccca
     1921 ccaaatcgta gaaagcttca actcttaatg cgcatgattt ctcgaatgag tcaaaatgtt
     1981 gatttgccca aacttcatga agagataggt acaagatcat tgatgataaa tactttttct
     2041 cgatgtgtcc tgtgttgcgc tgaagaagtg gatcttgatg agcttctggc ttcaagatta
     2101 gtttctttcc taatggatca tcatcaggaa attcttcaag tacccactta tttacaggct
     2161 gcagtggaga aacatcttga ctacattaaa aagggccatg ttaaaaatca tggagatgga
     2221 ctagttgttc ctttgccaac atattcttac tgtaagcaga ttagtgctaa agaatttgat
     2281 gaacagaaaa tttcaacttc ccaagctgca attgcagaac ttttggagaa tattgttaga
     2341 agtaaaagct tgccactaaa ggagaaaaga agaaagctga aacagtttca gaaggaatac
     2401 cccttgatat atcagaaaag gttcccaacc actgagagtg aagcagcact ttttgatgat
     2461 aaacctacaa tcaagcaacc aatgctgaat ttaagaaacc ccaagcttca cagtctgcga
     2521 tactgactta aaacttcaac aaatgaagcc atataagaga atatttctac ttaaaaggaa
     2581 gtctgttgat attacagttt tccttaaaag gacattatac aaggagatga caaaaccgtc
     2641 tttttgtctg tactaggctg ctaaaactac aggatcttag ctaagtgcct aacgaaaagt
     2701 aataccaaat attttaatta gaaacttttt taatgtaatg atctggtaag actatcagaa
     2761 tgaattgtat cttccagata aaattgtggt gctcttttaa aagaaaacac atctgtgtct
     2821 atatgtatat tagctaaaga acgggttgtt taggattgct tctttattta taagtatcag
     2881 attatgaaaa atattgtact cttgtttaat ctttttatac ttgtgatcta tttaactgta
     2941 tataaacaca cttgtagctt ggcttttatt attggacttt ggtttattcg aggacaaaag
     3001 gaggaatttt ttgagataaa gtctccctgt gcaccctatt ctaacctcaa actcattcct
     3061 cctgccttat tttcttgagt ggtaggaata ccgccattcc tgacttatat gtgtatttta
     3121 aaaatatgtg tgagattttt gttttccgct aaacattatc tcaattactt cagttttttc
     3181 cagaaatatg ttttgaatgc ttacatttac tatctattct gctataccaa aatagatgta
     3241 aaatagttat ttagcaacaa aaatgtgtct ttcattgttt cttaaatgtg tagactgtga
     3301 tgaataaagc aaaatttcct ctcttaa
//
