LOCUS       NM_001108749            2294 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus DENN domain containing 6B (Dennd6b), mRNA.
ACCESSION   NM_001108749 XM_001054735 XM_343313
VERSION     NM_001108749.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2294)
  AUTHORS   Linford A, Yoshimura S, Nunes Bastos R, Langemeyer L, Gerondopoulos
            A, Rigden DJ and Barr FA.
  TITLE     Rab14 and its exchange factor FAM116 link endocytic recycling and
            adherens junction stability in migrating cells
  JOURNAL   Dev Cell 22 (5), 952-966 (2012)
   PUBMED   22595670
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474027.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_343313.3, XM_001054735.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2294
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..2294
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /note="DENN domain containing 6B"
                     /db_xref="GeneID:362983"
                     /db_xref="RGD:1308012"
     exon            1..251
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     CDS             75..1832
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /note="protein FAM116B; hypothetical protein MGC38041;
                     family with sequence similarity 116, member B; DENN/MADD
                     domain containing 6B"
                     /codon_start=1
                     /product="protein DENND6B"
                     /protein_id="NP_001102219.1"
                     /db_xref="GeneID:362983"
                     /db_xref="RGD:1308012"
                     /translation="MEVLVGPGPRQAGGGLGAARSTSSGRAARTTEVPWARFSAWLEC
                     VCVVTFDLELGQALELVYPSDFRLTDKEKSNICYLAFPDSHSGCLGDTQFSFRMRQCG
                     GQKSLWHVDDRSYNSKAPLALQREPAHYLGYVYFRQVKDSSVKRGYFQKSLVLVSRLP
                     FVRLFQSLLSLIAPEYFEKLAPCLEAVCNEIDQWPAPVPGQTLNLPVMGVVIQVRIPS
                     RVDKLESSPPKQCDQENLLPAPVVLTSVHELDLFRCFRPVLTHVQTLWELMLLGEPLV
                     VLAPSPDVSSELVLALTSCLQPLKFCCDFRPYFTIHDSEFKELTTRTQAPPNVVLGVT
                     NPFFIKTLQHWPHVLRIGEPKMSGDLPKQVKLKKPSRLKTLDTKPGLYTSYTAHLHRD
                     KALLKRLLKGIQKKRPWDVQSALLRRYLLELTQSFIIPLEHYMASLMPLQKNITPWKS
                     PPQICPFRQDDFLQSLEHAGPQLTCILKGDWLGLYRRFFKSPHFDGWYRQRHKEMAQK
                     LEALHLEAICEANIEAWMKDKSEVEVVDLVLKLREKLVRAQGHQLPVKEVTLQRVQLY
                     IDTVIGSLPKDLQAVLCPP"
     exon            252..290
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            291..333
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            334..446
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            447..527
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            528..633
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            634..713
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            714..776
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            777..832
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            833..955
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1051
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1146
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1212
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1213..1277
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1278..1367
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1421
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1531
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1532..1634
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1635..1709
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
     exon            1710..2294
                     /gene="Dennd6b"
                     /gene_synonym="Fam116b; RGD1308012"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgactgctcc aaggcggccc aggtgaaccc cggcgcttct ccgcaacgtg ccgggtaccg
       61 ctggagctgc taccatggag gtgctggtgg gccccgggcc ccggcaagct ggcggagggc
      121 tgggcgccgc aagatccacg tcctccggcc gcgcggcgcg gaccacggag gtcccctggg
      181 cgcgcttctc tgcctggctg gagtgcgtgt gcgtggtcac cttcgatctg gagctgggcc
      241 aggcgctaga gctagtctat ccgagtgact tccggctcac agacaaggag aaaagcaaca
      301 tctgctacct ggcctttcca gactcccact cagggtgcct gggagacact cagttcagtt
      361 tccgcatgcg tcagtgtgga ggacaaaaga gcctctggca tgttgacgat cggtcgtata
      421 acagcaaggc tcccttggca ttgcagaggg agccagcgca ctacctgggc tatgtgtact
      481 tcagacaggt gaaggacagc tctgtgaaga ggggttactt ccagaagtct ttagtgctgg
      541 tgtcccgcct gccattcgtc cggctgtttc agtcactcct aagcctgatt gcccccgagt
      601 actttgagaa gctggcaccc tgcctggaag cagtttgtaa tgagattgac caatggccag
      661 cccctgtgcc tgggcagacc ctgaacctac ctgtcatggg agttgtcatt caggtgcgca
      721 tcccatccag ggtggacaag ctggaatcca gtcctccaaa gcagtgtgat caagagaacc
      781 tgctgccagc tccagtcgtc ctcactagtg tccacgaact ggatctgttt aggtgcttcc
      841 gaccagtgct aacccacgtg cagaccctgt gggagctcat gcttcttggg gagcccctag
      901 tggtcctggc accctcacct gacgtgtctt cagagctggt actagcccta accagctgcc
      961 tacagcccct gaagttctgc tgtgacttcc gcccctactt caccattcac gacagtgagt
     1021 tcaaggagct cacaactcga acccaggctc caccaaacgt ggtcctggga gtcacaaacc
     1081 ctttctttat caaaacactc cagcactggc ctcatgttct ccgaataggg gagcccaaga
     1141 tgtcagggga cctacctaag caggtcaagc ttaaaaaacc gtctcggctg aagaccctcg
     1201 acaccaagcc aggcctctac acctcctata ctgcccacct ccaccgggac aaagccctgc
     1261 ttaaacgact gctcaagggc atccagaaga agcggccatg ggatgtgcaa agcgccctgc
     1321 tgaggcggta ccttctagag ctcacacaga gtttcatcat ccctctggag cactacatgg
     1381 ccagcctcat gccactacag aagaatatta caccctggaa gagccccccc cagatctgcc
     1441 ccttccgcca ggacgatttc ctgcaaagcc tggagcatgc gggaccccag ctcacctgca
     1501 tcctcaaggg cgactggctg ggcctctaca ggcggttttt caagtccccc cattttgatg
     1561 gctggtatcg gcaacgacac aaagagatgg cccagaagct ggaggctctg cacctggaag
     1621 ctatctgtga ggcgaacatc gaggcttgga tgaaggacaa gtcggaggtg gaagtggtcg
     1681 acctggtcct gaaacttcgg gagaagctgg tacgggcaca gggccaccag ctccctgtga
     1741 aggaggtgac actgcagcgg gttcagctgt acatcgatac agttattggc tccctgccca
     1801 aggacctgca agcagtcctg tgccctccct aggacaggac aacttgtgtg gtcctgggga
     1861 cctaagtctg ccaagctccc cctcccttga aaggcaggct tccaccaagc tggggctccc
     1921 agcctggggc tcttacctca gcttcagccc cctccagaac cacctttgtc ccagcagtaa
     1981 aatgacattt ggaatgacag tctggtccct gactattggg ggattctgtg ctggcactgt
     2041 ctcacttctt gctggccccc acctgtccgc cacagctgga ggtgggagtg gtctagtagc
     2101 ctttactgat gtaggtgcct tcaccacctg ccccctcctg gctcccatct gcccacactc
     2161 caggccgcct tgtgttgggg gtcctttagc ccagcaggct tcccaactcc aagaaggagg
     2221 aggcagctgc cagggcaagc tcctttcctt tacacctcac tcgttctggg gagggaaggg
     2281 tactttgcct aggc
//
