LOCUS       NM_001134467            3895 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus DENN domain containing 6A (Dennd6a), mRNA.
ACCESSION   NM_001134467 XM_001057380 XM_224581
VERSION     NM_001134467.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3895)
  AUTHORS   Linford,A., Yoshimura,S., Nunes Bastos,R., Langemeyer,L.,
            Gerondopoulos,A., Rigden,D.J. and Barr,F.A.
  TITLE     Rab14 and its exchange factor FAM116 link endocytic recycling and
            adherens junction stability in migrating cells
  JOURNAL   Dev Cell 22 (5), 952-966 (2012)
   PUBMED   22595670
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On or before Sep 4, 2008 this sequence version replaced
            XM_224581.4, XM_001057380.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.53051.1,
                                           SRR26643289.37621.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-276               JAXUCZ010000016.1  1843803-1844078
            277-315             JAXUCZ010000016.1  1854541-1854579
            316-358             JAXUCZ010000016.1  1854677-1854719
            359-471             JAXUCZ010000016.1  1863010-1863122
            472-552             JAXUCZ010000016.1  1863839-1863919
            553-658             JAXUCZ010000016.1  1866394-1866499
            659-738             JAXUCZ010000016.1  1867774-1867853
            739-792             JAXUCZ010000016.1  1868918-1868971
            793-848             JAXUCZ010000016.1  1869923-1869978
            849-971             JAXUCZ010000016.1  1871188-1871310
            972-1067            JAXUCZ010000016.1  1871639-1871734
            1068-1162           JAXUCZ010000016.1  1875373-1875467
            1163-1228           JAXUCZ010000016.1  1878369-1878434
            1229-1293           JAXUCZ010000016.1  1878685-1878749
            1294-1383           JAXUCZ010000016.1  1879987-1880076
            1384-1437           JAXUCZ010000016.1  1887212-1887265
            1438-1547           JAXUCZ010000016.1  1887371-1887480
            1548-1650           JAXUCZ010000016.1  1887814-1887916
            1651-1725           JAXUCZ010000016.1  1889221-1889295
            1726-3895           JAXUCZ010000016.1  1889996-1892165
FEATURES             Location/Qualifiers
     source          1..3895
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..3895
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /note="DENN domain containing 6A"
                     /db_xref="GeneID:306229"
                     /db_xref="RGD:1306064"
     exon            1..276
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1857
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /note="hypothetical protein MGC38041; family with sequence
                     similarity 116, member A; DENN/MADD domain containing 6A"
                     /codon_start=1
                     /product="protein DENND6A"
                     /protein_id="NP_001127939.1"
                     /db_xref="GeneID:306229"
                     /db_xref="RGD:1306064"
                     /translation="MALRDQAVFGPGSRGSLDEAGAEGREAAALAAAGVALEDDEEDD
                     GRRGLLRWDGFSAWLHCVCVVGFDLELGQAVEVIYPQHCKLTDKEKTNICYLSFPDSN
                     SGCLGDTQFCFRFRQSSGRRVSLHCLLDEFDKDLPVYLKKDPAYFYGYVYFRQVRDKT
                     LKRGYFQKSLVLISKLPYIHFFHTVLKQIAPEYFEKNEPYLEAACNDVDRWPAPVPGK
                     TLHLPIMGLVMKVRIPTCHDKPGTTQLTQQADTHTSIILPTVHEVDLFRCFCPVFLHS
                     QMLWELVLLGEPLVVMAPSPSESSETVLALVNCISPLKYFSDFRPYFTIHDSEFKEYT
                     TRTQAPPSVILGVTNPFFAKTLQHWPHIIRIGDLKPAGEIPKQVKVKKLKNLKTLDSK
                     PGVYTSYKPYLNRDEEIIKQLQKGVQQKRPSEAQSVILRRYFLELTQSFIIPLERYVA
                     SLMPLQKSISPWKSPPQLRQFLPEEFMKTLEKTGPQLTSGIKGDWIGLYRQFLKSPNF
                     DGWFKTRRKEMTHKLEALHLEALCEEDLLLWIQKHTEVETVDLVLKLKNKLLQADREN
                     LPVKPDTVEKLRTHIDAIILALPEDLQGILLKTGMT"
     exon            277..315
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            316..358
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            359..471
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            472..552
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            553..658
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            659..738
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            739..792
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            793..848
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            849..971
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1067
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1162
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1163..1228
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..1293
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1383
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1384..1437
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1438..1547
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1650
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1725
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
     exon            1726..3895
                     /gene="Dennd6a"
                     /gene_synonym="Fam116a; RGD1306064"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcgcggt ccgcggcgga ggcggctcga gcggacaggg ggtggcggat ggctctgcgg
       61 gaccaggcgg tcttcggacc cggttcccgc gggtcgttgg acgaggctgg ggccgagggg
      121 cgcgaggcgg cggcccttgc ggcggcggga gtcgcgctgg aggacgatga ggaggacgat
      181 ggccgccggg gcctgctgcg ctgggacggc ttctcagcct ggctacactg cgtgtgtgtg
      241 gtgggcttcg acctggagct gggccaggcg gtggaggtaa tttatcctca gcattgcaaa
      301 ctcactgata aagaaaaaac gaacatttgc tatttgtcct ttccagactc aaattcaggt
      361 tgtctaggag acacccagtt ttgttttaga ttccgccaat cttctgggag gagggtctca
      421 ctgcactgtc ttcttgatga atttgacaaa gatttaccag tttacttaaa gaaagatcct
      481 gcatactttt atggatatgt gtattttcga caagttcgag ataaaactct taaaagaggc
      541 tacttccaga agtcattggt tttgatcagc aaactacctt atattcattt ttttcacacc
      601 gtactcaaac agatagcacc agagtatttt gaaaaaaatg aaccttattt ggaagcagcc
      661 tgcaatgacg ttgaccgatg gccggcccca gtgccaggga aaacattgca tctgcctatc
      721 atgggactag taatgaaggt gaggattccc acgtgtcatg acaagcctgg gactacgcag
      781 ttaactcagc aggcagatac acacacatct attattttgc ctactgttca tgaggtggat
      841 cttttcaggt gtttttgccc agtttttctt cacagccaga tgctttggga gttggtgcta
      901 ttgggagagc cccttgtggt catggcaccg tcgccgtcag agtcttcaga aactgtactg
      961 gccctcgtta actgtatttc tccattaaag tactttagtg attttcgacc ttacttcaca
     1021 attcatgata gtgaattcaa agaatatact acccgtactc aagctccgcc ctcagtcatc
     1081 ttaggagtaa ccaacccctt ttttgctaaa acactacagc actggccaca cattattcga
     1141 ataggagatc ttaaacctgc aggtgaaatt cctaagcaag ttaaagtgaa aaaactgaag
     1201 aacctaaaaa ctctggattc taaacctgga gtttatactt cttacaagcc atatctaaac
     1261 agagatgagg agatcattaa acaactccag aagggtgtac agcagaaacg tccttcggag
     1321 gcccaaagtg ttattctccg gcgctatttt ttggaactga cacaaagttt catcattcca
     1381 ttagaaagat atgtggctag cttgatgcct ttgcagaaga gtatttctcc gtggaagagt
     1441 ccaccccagc taaggcagtt ccttccagaa gaatttatga aaacgcttga gaaaacgggg
     1501 cctcagctca cgtctggaat aaagggcgat tggatcgggc tttaccggca gtttctaaag
     1561 tctccaaatt ttgatggctg gttcaagacc cggagaaaag aaatgaccca caaattggag
     1621 gcccttcatc tagaagctct ttgtgaagag gacctccttc tctggatcca gaaacacaca
     1681 gaagtagaaa cagtggacct tgtattgaag ctgaaaaata agctgttgca ggctgaccga
     1741 gagaatttac ctgtgaaacc tgacactgtg gagaagttac ggacacatat agatgcgatt
     1801 atcctcgcat taccggagga tctgcaaggc atactgctca agactggcat gacatgatac
     1861 ttagcagatt ctcctgccag aaaggactgt gaaccatgaa gcatactgac attttatcta
     1921 gacgcacaca ggagctgtct tggtggcagg agcacggaaa ccggcagcag ttgcgagata
     1981 caggtggaag gactgagcat ataaacagac atttttagtg cattctgtgg tggttccaca
     2041 atactggaat accgaacggc gtttccacgt ctgtaatcat gttctaaagt gctcttagga
     2101 gagacctgtg gggccatcca tgtaaggcct ccgaactgca gtgccggcac tgcagatatt
     2161 tttttaattg gtgctgcttt gcccaatcaa tgttgaaact caggggaata taaaaataat
     2221 gttcacactg gctgtcttct taagaaggaa aactgaactt ccgaactgta gttagatata
     2281 actggggctt atgtagtgcc ttccattgtc ctatatgttt cacagggtcc cgctgctaag
     2341 tttaaagctt tttctttttt aattatgata actttaaagg cattatatca agtaatcatt
     2401 tgcttaaaag tgtttctcgt tgccccttgt gtttattgac tggtatttta aattatcatg
     2461 tggttctcat gtcacaactc taccattttc acaagtaaga cttaggagtt tctccaaagg
     2521 aaggaggcat atgtagttct gcttatggga gagttgattt ctcccttccc ctttcctccc
     2581 tgggcctgtg taccctaatg agcacgaatg tcttttgaag acattcttac tatgaacacc
     2641 atagtcagtt gctttttaaa atagttattc ttatgtcaaa gtacccataa gccattcatg
     2701 gaataattat ttgagaattt tacacattat atgttgggtg acactatttc ccctaaatgg
     2761 atgattttca gaaggctttt cctgatgttg tttgacatgg gacctattgt gtaaatcagc
     2821 gttatacatt ggtttgtttg ttttcatttt gtttgtacta ccttgccaaa agcagactga
     2881 gatagtttgg tttgtgttta gatgggagtg tatgcagaag ccactgttca gataggtaca
     2941 catgaagtag cacagatgta aatagctgtg acttcagtcc cctcccttcc aaacagccaa
     3001 acctaggtgt atgtgtctgt cacactgtga cttcagaagc cacctcttgt tctccgttga
     3061 tgttatttct aagggcattc ctggtctagg aaggtttctc tgtgcttgtg actgtggtgt
     3121 catatccaag tgtgccctta gtcatggata cggtctcttg aagcatacca ctgtcctagg
     3181 aagaatatgg catttggatg aaatcatttg tctgaattga atgggttatt ttgtgaaaca
     3241 gtactgacct ttcagaaaag gggcaactac ttttatatgc taaagtactt cataactttc
     3301 tgggaaactt tatttaggta gaaatggcca tcttattatt tttcaaataa atgtatttta
     3361 ataatttcac aatttatatg cagtttgtga catgaatatg gaaatcatta gtgttatatc
     3421 aaggattttt gaaatatatt tctacaggat atatcatttg aagtttattt tgcacaccta
     3481 aagaaaaaca taaaatatca attagcatga aaatgctgtc tttacattta ccacatataa
     3541 cagaaactca acacatgttg aaaacgaaat catattctcc tactttatct cttaatttca
     3601 aattatgtct gtgcaagaat agcttaaggt tgcattggaa acccaaggaa gactgaacag
     3661 taacttaaat ttttatgtga ttttcagaat tgtctctttc tctgttttta aagagtttag
     3721 tattcaaacc ctgccgttta atgtgttgtc tccaccagca tcagaaggat tcagtgcttt
     3781 tagggtgtta tgtaatgcct agtgccttct atttacagtg gaaaagaggt tttgtggagg
     3841 catttatggt cattaccaaa aggtgaatta aaggccttgg attttaaaac gtgta
//
