LOCUS       XM_039108922            6876 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus DENN domain containing 5B (Dennd5b),
            transcript variant X1, mRNA.
ACCESSION   XM_039108922
VERSION     XM_039108922.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108922.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6876
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6876
                     /gene="Dennd5b"
                     /note="DENN domain containing 5B; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 35 ESTs, 2 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     16 samples with support for all annotated introns"
                     /db_xref="GeneID:100365679"
                     /db_xref="RGD:2318606"
     CDS             682..4590
                     /gene="Dennd5b"
                     /codon_start=1
                     /product="DENN domain-containing protein 5B isoform X1"
                     /protein_id="XP_038964850.1"
                     /db_xref="GeneID:100365679"
                     /db_xref="RGD:2318606"
                     /translation="MSGSGAAPGPGSGSSPAACRFAHYFVLCGIDADSGLEPDELAVL
                     YQWLEADRHGKSQDAANTTSGRNSLRGENFDQSPLRRTFKSKVLAHYPQNIEWNPFDQ
                     DAVNMLCMPKGLSFRTQADNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAM
                     QTLYQMHNAEQYSSVYASSSCSMDSLASSIDEGDATSLLKLQRYNSYDINRDTLYVSK
                     SICLITPLPFMQACRKFLLQLHKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFY
                     GVYEPVICQRPGPNELPLSDYPLREACELLGLENLVQVFTCVLLEMQILLYSQDYQRL
                     MTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQE
                     ANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLLQFGIPPEGSLHCSESATKLKN
                     MVLKDLANDKKNGNVPTNNVSVYELLKGSETIARLQALAKRTGVTVGKIDFPASLSEK
                     EKDLKLQCEEADLRDSQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTSREQM
                     QNFDKASFLSDQPEPYLPFLSRFIETQMFATFIDNKIMSQWEEKDPLLRVFDSRIEKM
                     RLYNVRAPTLRTSIYQKCSSLKEAAQSIEQRLMKMDHTAIHPHLLDMKIGQGKYEQGF
                     FPKLQSDVLATGPANNNRWVSRSTTAQRRKERLRQNAEHIGLDSDLREKYMQEARSLG
                     KNLRQPKLSDLSPAVIAQTNWKFVEGLLKECRMKTKRMLVEKMGHEAVELGHGEANIT
                     GLEENTLIASLCDLLERIWSHGLLVKQGKSALWSHLIQFQDREEKQEHLTDSPVALGP
                     ERRKSDSGVMLPTLRVSLIQDMRHVQNMTEIKTDVGRARAWIRLSLEKKLLSQHLKQL
                     LSNQPLTKKLYKRYAFLRCEEEREQFLYHLLSLNAVDYFCFTSVFTTIMIPYRSVIIP
                     IKKLSNAIITSNPWICVSGELGDTGVMQIPKNLLEMTFECQNLGKLTTVQIGHDNSGL
                     LAKWLVDCVMVRNEITGHTYRFPCGRWLGKGVDDGSLERILIGELMTSASDEDLGKQC
                     RTPPQQKSPTTTRRLSITSLTGKPAKPNAGQIQEGIGEAVNNIVKHFHKPEKERGSLT
                     VLLCGENGLVAALEQVFHHGFKSARIFHKNVFIWDFVEKAVAYFESTDQILDNEDDML
                     IQKPSCKTFCHYVNAVNTAPRNIGKDGKFQILVCLGTRDHLLPQWIPLLAECPAITRM
                     YEENALLRDHMTVNSLIRILQTIQDFTIVLEGSLIKGVDV"
ORIGIN      
        1 ttaagcatct gcatgtcagt ttaaaaatat ggtacagacg ttgtgggaaa tgacctcagc
       61 gtgctgtctc ccttctccaa agctacgtta ttgtttaggt taggttgggc gacatcctct
      121 ctggaagata ggatcctgct ctgcagctcg cgctctaacc cgctgatggg ggctgcaccg
      181 cgcaagagag gttgcctcac tattacagcc ggcgggcacg caccccgacg cgcccccgat
      241 ccttccgaac tctctggtgc gcgccctgga ccgcgcgcct ccgagctcta cgggcgctcc
      301 cgtcgcgcag cgcggttctg ttgacccgcg ggcgccagac gctgcgctcg ggcgggcgca
      361 gccgcggcgg cgcgggcctc cctagctgac actccccctg cgcgcccctc ccccgccgcg
      421 gcggaatccc gcccgcccgc gcgcgagccc gaggccgctt ccccggtacc agcgtctaga
      481 aggatcccgg ctgcggcgat tgcgcggcca tgggcgcgcc ggggtcgtcc tagggtcgcg
      541 gcggagaccg cagtccgagc ggcgcggtgg cctcctccgc gagggaagcc tgcgacgctc
      601 ctcggcgagg cttctcagcg gttcactccg gagagcctcc tccgcgaacc ccagcgacgg
      661 ccgcacaggc agcgcggcgg gatgagcggt agcggcgcgg caccgggccc gggctcgggg
      721 tcctccccag ccgcctgtcg cttcgcgcac tacttcgtgc tgtgcgggat cgatgcggac
      781 agcgggctgg agcccgacga gctggcggtt ttgtaccaat ggctagaagc agatcgtcat
      841 ggcaagagcc aagatgctgc aaatacaact tcaggcagga attcactaag aggtgaaaat
      901 tttgaccaga gtcctttgag aagaacattc aaatccaaag ttctggccca ctatcctcag
      961 aacatagaat ggaacccttt tgatcaagac gcagtgaaca tgctctgcat gcctaaaggg
     1021 ctgtcgttca ggacacaggc tgacaataaa gaccctcagt tccactcatt tataattacc
     1081 cgggaagatg gttctcgcac ctacggtttt gtgctcacct tttatgaaga agttacaagt
     1141 aagcagatct gcacagccat gcagacactg taccagatgc ataacgccga gcagtacagc
     1201 agtgtgtatg cttcatcctc ctgcagtatg gactcactgg ccagtagtat tgatgaggga
     1261 gatgcgacct cccttttgaa actccagcgg tacaactctt acgacatcaa cagagacacc
     1321 ctgtatgttt caaagagtat atgcttgatc acacctctcc ctttcatgca agcctgcagg
     1381 aagttcctcc ttcaacttca caaggcagtc acctcacagc agccaccacc cttgcccctc
     1441 gagagctaca tccataatat tctctatgag gtacccctgc cacctcctgg gaggtcactg
     1501 aaattttatg gtgtttatga acctgtcatc tgccagaggc ctgggcccaa tgaactccct
     1561 ctttctgact accctcttcg agaggcctgt gaactcctgg gattagagaa cctagtgcaa
     1621 gtatttacct gcgttctttt ggagatgcag atccttctct actcacaaga ttatcagcgc
     1681 ctgatgactg tggcagaagg cattaccaca ctcttgttcc cttttcagtg gcagcatgtt
     1741 tatgtaccca tactccctgc ttctctgcta cattttcttg atgcccctgt cccttatctg
     1801 atgggtcttc agtcaaaaga aggaactgac cggtctaaac tagaacttcc tcaagaggct
     1861 aatttgtgct tcgtggatat tgacaaccat tttattgagt tgcctgaaga atttccacag
     1921 ttccccaata aagtggattt tatccaagag ctgtcagaag ttcttctgca atttgggatt
     1981 ccccctgagg gcagtctaca ttgtagtgag agtgccacca aactgaagaa tatggttctg
     2041 aaagatttgg ctaatgacaa aaagaatggc aacgtcccca ccaacaacgt cagcgtgtat
     2101 gagttactga agggcagtga aaccatagcc cgcctccagg ctctggccaa gaggaccgga
     2161 gtgacggtgg gaaagatcga cttcccagct tctctgagtg agaaagaaaa ggatttaaag
     2221 ttgcagtgtg aagaggcaga cctgcgggac tcccagctca acgtacagct gcgcgaagtc
     2281 ttcgccaacc gcttcacaca gatgtttgcg gattacgaag cgtttgtgat tcagacggcc
     2341 caggacatgg agtcctggct gaccagccgg gagcagatgc agaactttga caaagcttct
     2401 ttcctctctg accagcctga gccttacctg ccatttcttt cacgcttcat tgaaacacag
     2461 atgtttgcta cctttattga taataaaatc atgtctcagt gggaagagaa agaccctctg
     2521 cttcgggtct ttgattctcg gattgagaag atgagattgt ataacgtaag ggcacccacc
     2581 cttcggacat ccatatatca gaaatgcagc agtttaaaag aagcagccca gtcaattgaa
     2641 caacgactga tgaaaatgga ccacactgca attcacccac atctacttga tatgaaaatc
     2701 ggtcaaggca aatatgagca agggttcttt ccaaagttac agtctgatgt cttggcgaca
     2761 ggaccagcca ataacaatcg ctgggtgagt cgaagtacca cggcacagcg caggaaagag
     2821 cgccttcgcc agaacgctga gcacattggg ctggacagtg acctacggga gaaatacatg
     2881 caagaggcac gaagtttagg aaaaaacctg aggcaaccaa agctgtcaga tctctcacct
     2941 gctgtgattg cacaaaccaa ctggaaattt gtagaaggct tattgaaaga atgcagaatg
     3001 aagaccaaac gcatgttggt agagaagatg ggacatgaag cagtggagct gggccacgga
     3061 gaagcaaaca tcacgggttt ggaagagaac accttgatcg ccagcctctg tgaccttctg
     3121 gagaggattt ggagccacgg cttactggtc aagcagggaa agtctgcctt gtggtcacat
     3181 ttgatccagt ttcaggatcg agaagagaaa caagaacacc tcacagactc cccagttgcc
     3241 cttggaccag aaagaagaaa atctgactca ggagttatgt taccgacact cagagtctct
     3301 cttattcaag acatgagaca tgttcagaac atgactgaga tcaagactga tgttggacgg
     3361 gctcgggcgt ggataaggtt gtccctagaa aagaagcttt tgtcccagca tctcaagcag
     3421 ttactctcta accaaccact aaccaagaag ctttataagc gctatgcttt tctacgctgt
     3481 gaagaagaaa gagaacagtt tctttaccat ctgctttccc tcaatgctgt ggactacttc
     3541 tgctttacca gtgtgttcac cactatcatg attccttata gatcagtgat cattccaatt
     3601 aaaaagctga gcaatgcaat cattacctcg aacccgtgga tctgtgtttc gggagagctg
     3661 ggagacaccg gagtgatgca gattccaaag aacttgcttg agatgacttt tgagtgccag
     3721 aacctgggga agctcactac agttcagatt ggccatgata actctggact gctagctaaa
     3781 tggctagtgg attgtgtcat ggtcagaaat gaaatcacag gacacacata cagattccct
     3841 tgtgggcggt ggctggggaa aggtgtcgat gatggcagcc tggagagaat tcttattgga
     3901 gaattgatga catcagcttc agatgaagac ctgggaaagc agtgtcggac tccaccacag
     3961 cagaaatctc ccacgacaac caggagactg agtattacct cactaacagg aaagcctgcc
     4021 aagcccaatg ctggacagat ccaagaagga attggagaag ctgtgaacaa tattgtgaag
     4081 cattttcaca aacctgaaaa agagagagga agcctcacag tgctgctgtg cggagaaaat
     4141 ggcctggttg ctgccctgga acaagttttc catcatgggt tcaaatctgc ccgcatcttt
     4201 cacaagaatg tcttcatctg ggacttcgta gagaaagcag tggcttattt tgagtccact
     4261 gaccagattt tagacaatga agatgatatg ctcattcaga aaccatcatg caaaaccttc
     4321 tgccactatg tgaatgctgt caatactgca cccaggaaca ttggaaagga cggcaaattc
     4381 cagattctcg tttgcctggg aacaagggat cacctgctcc cacagtggat tccattgcta
     4441 gcagaatgtc ctgccatcac ccgaatgtat gaagagaatg cactccttcg agaccacatg
     4501 actgtcaatt cccttatccg cattctgcag accattcagg atttcaccat agtcttggaa
     4561 ggatcactaa tcaaaggagt ggatgtgtaa agcagtcgac agaaactctt catctacccc
     4621 tggctcatga cgcttcctca gttatgggga cctatctgga ccggtctgac catagcgcgc
     4681 actgcggggg cagtgcacta gaagccccag attgaacagt ctccactctg cagacaaggc
     4741 aaagtgctgt gttgtagttc atttgaacct gaaatttagt ataaaataga gtattttcat
     4801 gtgttagaag tgtgtaaata tgctatcttt aagaaatatt actctaataa gatacttttc
     4861 ttagattgaa tattcctgtg acttaaaata agtagcttaa aaatgttggg ggcggggaaa
     4921 gtggtgctag tcaggaagaa gccagtaaat gtgtaaatag tgcaacccag gcaggcttct
     4981 ttttccctcc aggtctcaca gaggaaccag aatgcttcgt tctgaagcag ccatccctcc
     5041 tggagtccca tcctgtgtgc agtgaatgta tacagcttta cataatgtac agcagtcctc
     5101 gttggtcttt aagttataaa ccatttaata catttgaatt atgagtcatt tttctagttt
     5161 tggggaagtt ttagttggcc cccagcaagg tttggtggct cacacctcca atcccagcac
     5221 tggggaggca ggggcagggg catctgagtt gcaggccaga cagagctaca caagagagag
     5281 agagagagag agagagagag agagagagag agagagagag agagaacaca aataccagat
     5341 cccaagagct tggctaattg gaaagcaaac acagaagccc tgagaagcat gggcttaaaa
     5401 cttctttact ttagaaagat taacctggag gcttcattgt tggcgttttt tattgctgtt
     5461 atttgacaga acttttgaga taatgaattt tagtattagt catatagcca caactgcaag
     5521 aaacagtgtg actcagttct attaactcgg ccatctaaac tctgtaactg gagttaatct
     5581 accagtccat tctttgttag gtcccagcca ctccctcggt ctgccccatc cccctctcag
     5641 gaaatggaag gaatgtggaa gaaggaggga ggtctcagtg tgatttggaa tgcttttgtg
     5701 aaggtatttg ttgaccatga taatgcaaat agcagaagcg gtgagaaaga acttagcctt
     5761 tctgggtgtt tcagggaaat gtaaagcaat ggcccagaga agttaaaagc cactgcctca
     5821 gactgaggag tgaattagac acaagagaca attcaggaag cctttaagtt atacctttct
     5881 agtttggtag cttatttatt ttttaagtta agtaaatatg ttagcaacta cataaatctt
     5941 tatctttttg gtaagtaagt tgtggaactc ttaattaagc actgatacct tgttagtagc
     6001 aaaattgcct cagcagagct ccaggtttta ttccctgttg tagctgaaaa ccagagccat
     6061 ggcctctcag gatccgtgtg caatctcagg gccctgggct cttgccagcc gtgctgtttt
     6121 tccttattta ctggaagaag agactaatag atcaagtgcc tcatgccctt tatcaaaaac
     6181 taaggaaggg tctctgaaga tacatttaca aacccatgga aagggctcag aatatgtctc
     6241 tagatgacct gggtaaccca gaggtttgct tacctaaaat aaaggtgttt atactagaat
     6301 gagactattc tagagacaga tctactgtgg gaacatccag aagttagatg ccgtccttcc
     6361 cggggtttta ccgttgtctt cccgtggtgg acttttaagt cagtattcca cagttgggtc
     6421 attggtgcag ccccttccag acattattac ccgatatcat ttctcctgtt gaatcttcag
     6481 tcacctgtac agatatgaaa ctctatctct gtgctactta atgaggactg aaacctaagt
     6541 taattcattt tgttgttgtt agtgaaacag gatcccattg tgtatcccag gctggccttg
     6601 gaactccatt tgtagaccag gctcacctat ctagaactca cagagatcta cctccctcca
     6661 cctcctgagt gaggggattg atctgagtgc cctgcccagc aaactgctct taatctctta
     6721 ggcattacat cgttgtaaaa gtggggcaga gttgtgttcc agcttgagtt taaaactggt
     6781 acttaaaaaa agaaaagtag tagtagtagt accaaaaaaa aaaaaaaaaa aaaaaaaaaa
     6841 aggcttgttc cacgtgatat cctttggatg gactag
//
