LOCUS       XM_235398               5372 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus DENN domain containing 3 (Dennd3),
            transcript variant X1, mRNA.
ACCESSION   XM_235398
VERSION     XM_235398.8
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jan 17, 2024 this sequence was replaced by
            NM_001427258.1.
            
            On Jan 21, 2021 this sequence version replaced XM_235398.7.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5372
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5372
                     /gene="Dennd3"
                     /note="DENN domain containing 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 14
                     ESTs, 5 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 145
                     samples with support for all annotated introns"
                     /db_xref="GeneID:315055"
                     /db_xref="RGD:1311559"
     CDS             203..4039
                     /gene="Dennd3"
                     /codon_start=1
                     /product="DENN domain-containing protein 3 isoform X1"
                     /protein_id="XP_235398.7"
                     /db_xref="GeneID:315055"
                     /db_xref="RGD:1311559"
                     /translation="MAEPSARHLSLPSGLLELCALLGASQDSLRGLEQIAQKRGVNGA
                     SSLVPEVLSVFVPPFTTKEDGQVVGASCTLSKGRRRSFRKKREKPRMESWKSHPGDSK
                     GPDSEDVTIPGGVDLLALPQLCFPGGVCVASEPKEDYIHFLVLTDVCGNRTYGVVAQY
                     YRPLHDEYCFYNGKSHWEPSMSSARRFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLC
                     KDFEVDNHIKDFAARLSLIPSPPPGPLHLIFNMKPLQVVFPSRADPESPIIDLDLHLP
                     LLCFRPEKVLQILTCILTEQRMVFFSSDWALLTLMAECFVAYVHPLQWQHTFVPILSG
                     QMLDFVMAPTSFLMGCHLDHFEEVRKEADGLVLIDIDLGSVTCSKSSDEDVDIPDVPL
                     LLAQAFIQRVQSLQLHPDLHLAHLSASTDLNEGRARRRAWQQALNCKIQHITLQLLVG
                     IFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFA
                     RMDLDTQSEEDRIDRMLISPRRPTVEKMASRKASPLNIAHRRMVVSMPNLQDISLPEL
                     PPRNSSLRIMDTSSCKSSSPVLKVTPKSTYTFKIPEIHFPLVSQCVQAYFTDLVTLLS
                     KAMALLGPGDSLLLARYFYLRGLIHLMQGQLLNALLDFQSLYKTDIRIFPADLVKGMV
                     DSMSASERAQAERTPELRRLITEVFDKQGEAPKVDDAVKNFELPKKHMQLNDFVKRVQ
                     ESGIVKDTTIIHRLFDALTVGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLVDHL
                     DRNECVYKLSSSVKTNRGVGKIAMTQKRLFLLPEGRPSYVEIATFRNIEEVKSTTVAF
                     LLLKIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKKLADDHKDPQYVQQALT
                     NVLLMDAVVGTLQSSGAIYAASKLAYFDKMKNELPMAVPKTTSETLKHKINPSAGETA
                     PQAIEVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTIHQHCFKVGSSKV
                     NCMVMAEHSQVWVGSEDSVIYIINVHSMSCNKQLTDHRSAVTGLAVPSGKKPSAVYSC
                     SLDGTVLAWNVSTLRVISRFQLQHGDLMSISLHNDRVFCCTARSILVVTLQGFVRQEL
                     RIQPSEEPSASFLAIQLLPEEQQLWVACTGVSELYIWSLKDLGQPPQKTHLQDCTEVT
                     CMIRVKRQIWVGGRGLSQGKTRGKIYVMDVEKVTLEKELVAHSDTVRTLCSAEDRYVL
                     SGAGGEEGKIAIWKVE"
ORIGIN      
        1 gtggacgagc ccggctccct ccaggccccg cccattccgc ggacgcggct ggctggcaac
       61 cgaccgaaga gaagcgccga ggccttgtct gaggcgctct gtggggtctg gcttgaaggc
      121 gccagcgtcc tctgattcga gtcatcgctg ccgggcaatc gagggctcgg agcgcagtgt
      181 gcaaggcggt ggcgggaagg tcatggcgga gccctcggcg cgacacctgt cgctgccctc
      241 ggggctgctg gagttgtgcg cgctgctggg tgcctctcaa gacagcctcc gcggcctgga
      301 gcagattgcc cagaaacgag gagtgaacgg cgcctcttcc cttgtccctg aagttctgtc
      361 tgtttttgta cctcctttca ccacaaaaga ggatggccag gtggtgggag ccagctgtac
      421 tctcagcaaa ggcaggaggc gttccttccg gaagaagcgc gagaagccca ggatggagtc
      481 ctggaagagc caccctggag actcaaaggg gcccgattct gaggatgtca ccatcccagg
      541 aggtgtggac cttcttgccc tgcctcagct gtgctttcca gggggtgtgt gtgtggcttc
      601 ggaaccaaaa gaggattaca tccatttcct ggtgctcacg gatgtctgtg ggaatagaac
      661 ctacggtgtg gtcgcccagt actatcgacc cctgcatgat gaatactgtt tctacaatgg
      721 caagagccac tgggagccca gcatgagctc tgctagacgc ttcgtgccct ttgcagtatg
      781 tgtggtgtcc cggttcccat attataactc cctcaaggac tgcctctcct gtttactgac
      841 tcatctgaag ctctgtaaag actttgaagt tgacaatcac ataaaggatt ttgctgcgcg
      901 actgtcctta atacctagtc ccccgcctgg gccgctccac ttgatattta acatgaagcc
      961 actgcaggtc gtgtttcctt ctcgagcgga cccagagagc cccatcatcg acttggacct
     1021 tcacctgccc ctgctgtgct tccggcctga gaaagtgttg cagatcctga cctgtatctt
     1081 gacggaacag cgcatggtgt tcttctcctc agactgggcc ctgctgactc tcatggctga
     1141 atgcttcgtg gcctacgtcc accccctgca gtggcagcac accttcgtgc ccatcctgtc
     1201 gggtcagatg ctggacttcg tcatggctcc cacgtctttc ctcatgggct gtcatctcga
     1261 ccactttgaa gaagtcagaa aggaagctga tggcctggtc ctgattgaca ttgacctcgg
     1321 gagtgtcacc tgctccaagt cttctgatga ggacgtagac atccctgacg tcccccttct
     1381 gctggcacag gccttcattc agagagtcca gagtctccag ctgcacccag atttgcacct
     1441 tgcacacctg agcgccagca cagacttgaa tgagggccga gcccgccgcc gagcctggca
     1501 gcaggctctc aactgcaaga tccagcatat cactctgcag ctgctcgtcg gcatcttcag
     1561 ggaggtgaag aatcacttga attatgagca ccgcgtcttc aacagcgagg agtttctcaa
     1621 gacgagagca gcaggggacc agcaatttta taagcaggtc ttggacacct acatgttcca
     1681 ctccttcctg aaggcccggc tcaacggcag gatggacgcc tttgctcgga tggacctcga
     1741 cactcagtct gaggaggaca ggatagacag gatgcttata agtccaagga gacctactgt
     1801 ggagaagatg gcgtctagga aggcctcacc cctgaacatc gcacacaggc gcatggtggt
     1861 cagcatgccc aacctgcagg acatctccct gcccgagctg ccacccagaa actcatcgct
     1921 tcggataatg gatacctcga gctgcaaaag cagcagtcca gttctcaaag tgacccctaa
     1981 gtcaacatat acattcaaga tccccgagat ccacttcccg ctggtgagcc agtgcgttca
     2041 ggcatacttc acagacctcg tcactctcct gagcaaggcc atggccctgt tgggccctgg
     2101 tgactctctg ctcctggcca ggtacttcta cctgcgtggt ctcatccact tgatgcaggg
     2161 gcagctgctg aatgccctct tggatttcca gagcctgtat aagaccgaca taaggatctt
     2221 cccagctgat cttgtcaagg ggatggtgga ctccatgtcg gcctcggagc gggcccaggc
     2281 tgagcggacg cctgagctca ggcgactcat cactgaggtc tttgataagc aaggagaggc
     2341 ccccaaggtg gacgacgccg tgaagaactt cgaactgccc aagaagcaca tgcaactcaa
     2401 tgacttcgtg aagcgggtcc aggagtcggg gatcgtgaag gataccacca tcatccaccg
     2461 tctgttcgac gccctgaccg tgggacacga gaaacagatt gaccctgaga cgttcagaga
     2521 tttttacact tgctggaagg agacggaagc agaggcacaa gaggtcagcc tgcccgcact
     2581 gcttgtggac catctggata ggaacgagtg tgtctacaag ctgtcaagct ccgtgaagac
     2641 caatcgtgga gtcggcaaga ttgccatgac ccagaaacgc ctgttcctgc tccctgaggg
     2701 gcggcccagc tacgtggaga tcgccacctt caggaacata gaggaagtca aaagcaccac
     2761 ggtggcattt ctcctcctga agatacctac cttaaagatc aagacggtgg ccaagaagga
     2821 agtcttcgag gcaaacctca agtctgaatg tgacctctgg cacctcatgg tgaaggagat
     2881 gtgggctgga aagaagctgg cagatgacca caaggaccct cagtacgtcc agcaagcact
     2941 gaccaacgtt ctgcttatgg atgccgtggt tggcacgctg cagtcatctg gtgccattta
     3001 cgctgcctcc aagctggcct actttgacaa gatgaagaat gaactgccca tggcagtccc
     3061 caaaacaacc tcggagaccc taaaacacaa gattaaccct tcagctggag agaccgctcc
     3121 ccaagccatt gaagtcttgc tgtatactcc agggcgcctc gatcctgcag agaaagttga
     3181 agacgcacac cccaagctgt ggtgcgccct gaatgaaggc aaagtggttg tgtttgatgc
     3241 ttcctcttgg accattcacc agcactgctt caaagtgggt tcctctaaag tgaactgtat
     3301 ggtgatggca gagcacagcc aggtgtgggt aggctccgag gactccgtca tctacatcat
     3361 caacgtccac agcatgtcct gcaacaaaca gctcacggat caccgttctg cggtcactgg
     3421 cttggccgtg cccagtggga agaagcccag tgcagtctac tcctgcagtc tggatgggac
     3481 agtcttggcg tggaatgtta gcacgctccg agtgatcagc cggttccagc tgcaacacgg
     3541 cgacctcatg tccatcagcc tgcacaatga ccgcgtgttt tgttgtacag cccgcagcat
     3601 cttggtggtg acgctgcagg gctttgttcg tcaagagctg aggatccagc cctctgagga
     3661 gccatctgct tccttcctgg ccatccagct tctgcctgag gagcagcagc tgtgggtggc
     3721 ctgtaccggg gtcagtgagc tgtatatctg gagcctaaaa gacctgggcc agcctcctca
     3781 gaagacccac ttgcaagact gcacggaggt cacctgcatg atccgagtga agaggcagat
     3841 ctgggtgggc ggcagggggc tgtctcaggg aaaaacccga gggaagatct acgtgatgga
     3901 cgtggagaag gtgacgttgg aaaaggagct ggtggcacac tcggacaccg tgaggaccct
     3961 gtgttccgct gaggaccgct atgtactgag tggagcaggc ggggaggagg ggaaaatcgc
     4021 catctggaaa gttgagtgaa agctccgtac tgaaccggtg ttgtcctgtg aggggacgcc
     4081 cccctgtcac accactgtgg ccgtggctag ccagttgggg cctgtctgct ccaggggccc
     4141 tttcctccct gggtgagcag ctccatcgta ttgctgacag cctctactgt aaagttacct
     4201 cacgtcaccc agaaacttcc agaatccaca cctgggagcc agcacctcag ctgccaacct
     4261 ggcatgtgac ctgtggtctt caaggctggc ctctctccct tccctcttcc tgtttactct
     4321 gcaaacactc gggctcagtg gtatgtgatg gccagtatgt cacagccaca gagcctttca
     4381 ggtttctaca aacttcctga ttccagagag gcttctgagt atttgaaggt aaacaccaag
     4441 aactggcctg cactgggcag gtgattcccc cttcaaggaa ggggaccaag gcctgcccca
     4501 gggaggggac aatactggtc aggcttgtct gtgtagaaat tgggcaactg agtggctctg
     4561 tcttagcatt aaaattttga tgaagaccaa cgactacaga caagaaagtc acctcagaag
     4621 cacatgcatg cgtgactgtc tcattggctc atagcctatc tgcagtgtgt gtctcctgca
     4681 tgtgtaaacg cctctctatt caactacaca tagctatctg caccgaggtt tgtgaatgtg
     4741 tttaccacac tgatccaatg tcatcctgga aatgttctgt gaggtgggtt acataatggc
     4801 tgctggacat aggatatggc ctatttcctg tgtatccttc tgtgaagatg ttctgcatgg
     4861 agccctctgg atcccctgcc ttgggttttc aagactccat gtccaccact ggagagtgga
     4921 gaggcagtca ctaagaagtt acagaggggt tggggattta gctcagcggt agagcgcttg
     4981 cctagcaagc gcaaggccct gagttcggtc cttagctccg ggggaaaaaa aaaagacaaa
     5041 aaagaagtta ccaatggtct atgcctgtct ctgacgtcag gccagggtcc agaggtacgt
     5101 agcccatgca tgtgaagatg cgggtaaggg cttgactggt ctgcaccact gcctgcaggt
     5161 tcccttgaat gtagtgcaga ggatctcaga gccacaccca tccctagagt ctgtgttccc
     5221 tgaggggtgt tccttatgtc cagaaggaca atgtcggtca agggcacgga ttcaaactgt
     5281 ctttgtaaaa ggcgattcta agttatttaa tgccagtccg tgtatgacca ggtgtttaca
     5341 acttgtgata ataaaccctt tttgttaaca aa
//
