LOCUS       XM_039109021            4741 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus DENN domain containing 2A (Dennd2a),
            transcript variant X2, mRNA.
ACCESSION   XM_039109021
VERSION     XM_039109021.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039109021.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4741
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4741
                     /gene="Dennd2a"
                     /note="DENN domain containing 2A; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 18
                     ESTs, 2 long SRA reads, 9 Proteins, and 100% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 14 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:312257"
                     /db_xref="RGD:1306142"
     CDS             610..3606
                     /gene="Dennd2a"
                     /codon_start=1
                     /product="DENN domain-containing protein 2A isoform X1"
                     /protein_id="XP_038964949.1"
                     /db_xref="GeneID:312257"
                     /db_xref="RGD:1306142"
                     /translation="MLEARVDMLSSNMIISGPAADLGAKEASRPLKKQLSSVQNPGPS
                     TQARAQPLSIKDKISKWEGKKEPPASDPARQTDGQEDYLPSCRVERRGSELTRTKNGM
                     RLETESLQNDSRTRTMCQDAERLPGLRQIDGQPEPSQPRGRELKPSDLRFQSDHLSVL
                     RQVKRLEKALKDGSAGLDPQLPGTCYSPHCLPDKTEEDQPIPESHESGVSLASGRRAH
                     HSEVREPGPEISEEWKGQENVYRGSRWHPQKPFINPVPKPRRTFKHAGEGDKDGNPGI
                     SFKKEKRNLPPLPSLPPPPPPLPSSPPPTSVNRRLWTGRQRPSADHRKSYEFEDLLQS
                     SSENSRVDWYAQTKLGLTRTLSEENVYEDILDPPMKENPYEDVESHGRCLGKKCVLTF
                     PGSPTSSIPDTSTKQSLSKSAFFRQNSERRNFKLLDTRKLSRDGTGSPLRTSPPSTPS
                     SPDDTFFNLGDLQNGRKKKKIPKLVLRINAIYEARRGKKRVKRLSQSTESNSGKVTDE
                     NSESDSDTEEKLKAHSQRLVNVKSRLKQAPRYSSLDRDLIEYQERQLFEYFVVVSLHK
                     KQAGAAYVPELTQQFPLKLEKSFKFLREAEDQLKAIPQFCFPDAKDWSPVQEFTSETF
                     SFVLTGEDGSRRFGYCRRLLPGGKGKRLPEVYCIVSRLGCFSLFSKILDEVEKRRGIS
                     PALVQPLMRSVMEAPFPALGKTITVKNFLPGSGTEVIELCRPLDSRLEHVDFESLFSS
                     LSVRHLVSVFASLLLERRVIFIADKLSTLSKCCHAMVALIYPFSWQHTYIPVLPPAMI
                     DIVCSPTPFLIGLLSSSLPLLRELPLEEVLVVDLINDRFLRQMEDEDSILPRKLQVAL
                     EHILEQRNDLACDQDGGPLDCVHGPESSSLSEVVSEAFVRFFVEIVGHYSLFLTSGEE
                     RSLQREAFRKAVSSKSLRRFLEVFMETQTFRGFIQERELRRQDAKGLFEVRAQEYLET
                     LPSGEHSGVNKFLKGLGNKMKFLHKK"
ORIGIN      
        1 ccagctgcgg attagctcac tggagccgcg ggatgggtcg ggaggagggg gcgcacgtca
       61 ctgcagacgg tcgcggcgca gcccaaggca gaggaagggg ccgcgcgcgc cagaggccgg
      121 aggggacgca acgcgcctcc caggccggag gcagcgggga ccggacgaga gcgcgcgcgg
      181 cggggactcg aggggctccc ggcggccggg ggaggccgcg cggacaaagg cgcggagggc
      241 agcgggccat ggcgccccag gtccccgccg cccccgcccc gggcaaccgc gagttgcgtc
      301 ccagaacccg cggagccgcc tcccgtggag agcccttgca tgtatccacc gtgcagagcc
      361 acggtagtgt ctgtgactga gtgacgtctg ctctgtcggt ggctgtcagc aacacacact
      421 aacctgggtg gccatgttct cactcatctg tcgtcttccc tcttgtcaag agaaaggaaa
      481 ccggtcaaag cagaagttgc aaagcctagg gaagcgtcta gaagacaact gcttgggagg
      541 tccgtttctt tgcaaaagac taatccagca cctcccttgg gaaggagtcc ctcaagccct
      601 cacaccctca tgctggaggc aagagtggac atgctcagct ccaacatgat catcagtggc
      661 ccggctgcag acctcggtgc taaagaagcc agcaggccct tgaagaagca gctcagtagt
      721 gtccagaacc ctggaccatc tacccaagcc agagcccagc ccctcagcat aaaggacaag
      781 atatccaagt gggaaggcaa gaaggagcca ccggcctccg accctgccag gcaaacagat
      841 ggccaagagg actacctgcc gtcctgcagg gtagagagac gaggcagcga actcaccaga
      901 accaagaatg gaatgaggct tgaaacagag agcttgcaaa acgacagcag gacaagaacc
      961 atgtgtcagg acgcagaacg gttgccaggc ctgaggcaga tcgatggtca gccagagccc
     1021 agccagcccc gaggtcgtga actgaagccc agtgacctac gctttcaaag tgaccatctc
     1081 tccgtgctga gacaggtcaa gaggctagag aaggccttga aggatggctc cgctggcttg
     1141 gacccccagt tgccggggac ttgttattca cctcactgtc tgcctgacaa gacggaggaa
     1201 gaccagccca ttccggaaag ccacgaaagt ggggtctcct tagcatctgg ccggagagct
     1261 caccactcgg aggtcaggga gccgggcccg gagatctcag aggagtggaa aggccaggag
     1321 aatgtgtaca ggggctccag gtggcacccc caaaagcctt tcatcaaccc cgtccccaaa
     1381 ccccgcagaa cattcaaaca cgctggagaa ggggacaagg acggaaaccc aggcatcagc
     1441 ttcaagaaag agaagagaaa cctgcctccc ctgccctctc tgcctccccc tcccccaccg
     1501 ctgccttcct cccctcctcc cacttctgtg aatagaagac tgtggactgg gaggcagaga
     1561 cccagtgctg accacagaaa gtcctatgag ttcgaggact tactgcagtc ttcctctgag
     1621 aacagcaggg tggactggta tgcacagacc aaattgggac tcacacgcac tttatcagag
     1681 gagaacgtct atgaagacat tctagatccg ccaatgaagg aaaatcctta tgaggatgtg
     1741 gagtcacatg gccgctgcct gggcaagaag tgtgtcttga ctttccctgg atctcccacc
     1801 tcctccatcc cggacacgtc caccaagcag tccttgtcca agtctgcatt tttccggcaa
     1861 aactcagaga gaagaaactt caagctgttg gacactagga agctgagccg ggatggaact
     1921 gggtccccgc tgagaactag ccctccctcc acacctagca gcccggacga cactttcttt
     1981 aaccttggag acctacagaa tggcaggaag aagaaaaaga tccccaagct ggtgttgagg
     2041 atcaatgcca tttatgaggc ccggagagga aagaaacggg tgaaaaggct atcccagtcc
     2101 acggagagca actcaggaaa agtgacagat gaaaacagtg agtctgacag cgacacagag
     2161 gagaagctaa aagctcacag ccagcgcctg gtcaatgtga agtcacgcct gaagcaggcc
     2221 cctcggtact catcacttga ccgagatctc attgagtacc aagagaggca actcttcgag
     2281 tactttgtgg tcgtatctct acacaagaag caggcagggg ctgcctatgt gccagagctc
     2341 acccagcaat ttcctctgaa gttagaaaag tcattcaagt tcctgagaga ggctgaggac
     2401 cagctgaagg ctattcccca gttctgcttc cctgatgcca aggactggag tcctgtccag
     2461 gagtttacca gtgaaacgtt ctcgtttgtc ttaactggag aagatggcag cagaaggttt
     2521 ggctactgcc gaagactgct gcctggaggc aaagggaagc gacttcctga ggtttactgc
     2581 atcgtgagcc gcctgggatg cttcagcctc ttttcaaaga tcttggacga ggtggaaaag
     2641 agaagaggaa tctcccctgc cctggtgcag cccctcatga ggagtgtcat ggaagcccct
     2701 ttcccagccc tgggcaaaac catcactgtc aagaacttcc taccaggttc ggggactgag
     2761 gtgattgagc tgtgccgacc gctggactcc cggctagagc atgtggactt tgagtctctg
     2821 ttctcctccc tcagtgtccg acacttggtc agtgtttttg cctccctact tctggaaagg
     2881 agggtcatct tcatcgcaga caaactcagc actctgtcca aatgctgcca cgccatggta
     2941 gcactcatct accccttcag ctggcagcac acctacatcc cagtgttgcc gcctgccatg
     3001 attgacatag tgtgctcgcc cacgcccttc ctcatcgggc tgctctccag ctcgctgcca
     3061 ctgctcaggg agctgccact ggaagaggtt cttgtggtcg atctcatcaa tgatcgattc
     3121 ctcagacaga tggaggacga ggattccatt ctgccccgga agcttcaggt agccctggaa
     3181 cacattctgg agcagaggaa cgatctggcc tgtgaccagg acgggggccc gctggactgt
     3241 gtgcatgggc ccgagtccag ttccttgagt gaggtggtct ccgaagcctt tgtccgattt
     3301 tttgtggaga ttgtgggcca ctactccctg ttcctgacgt cgggcgagga gcggagcctg
     3361 cagcgagagg ccttcagaaa agctgtctcc tctaagagct tacgacgctt cctggaggtc
     3421 ttcatggaga cccagacttt ccgtggcttc atccaggagc gggaactgcg caggcaagat
     3481 gccaaaggtc tgtttgaagt ccgagcccag gagtacctag aaaccttgcc cagcggagag
     3541 cacagcgggg tcaataaatt cctcaaggga ctgggcaata aaatgaagtt tctccacaag
     3601 aaatagccct catcttggct caagggaaga cctcctccct agcgccccag tcctcccagg
     3661 atgggccctg agctgggcaa gtggcagacg ctcagaacag ctctgggaga gacccgccag
     3721 cagacagact gttgttactc tggttggttg gttggttcta ggaatcttta agtcttagat
     3781 attaaaagag aagaagaagg gaagtgtttg gctcttcatt cagctctcct gccccacctc
     3841 atctcttctg ggccagcttg ttgacaactg tggagccagg acatgggaag ggtggcagcc
     3901 gcagaagcta tgccactggt tcttcccgac tagtctatga cgccacctgg tggcagagac
     3961 tgtggacttt actgttcttg acttcatttt tcccccctta gaagccatat aaaaccattc
     4021 atgcccaaaa agtctgtgac ctttagaggg acacataaaa acaggaaatc ttctcaactg
     4081 gtaataaaat gttctaaggg tcctgaagtt tctatttcct gtgtcccaac catgacactt
     4141 aggccactgc tgtgaaccta gtcctcttgg ccaacatagc tgggaaaggc ttctgtagtt
     4201 gcttctctta atgagaggga ggacccagat cagctgacct gtggggccag tgagaatctg
     4261 caagagtcct gtgtgcagca aaagaaaggt tctcaggctg gcctcggggc tatcactctg
     4321 aaactgctgg gccccggtga cggccaccag taattaacca catctggact gcctctgacc
     4381 tgggcaggat taatagggct gtgtggctag ggtcgaggga agcctgagaa agaatgtgag
     4441 catgggggct gaggaaccca ccacacaagc tccccgttta ggtaacctta ctgacagcaa
     4501 tattccgtgt atttttatat tgcccccagg tgaccatggt tagtattttg gaatatacgt
     4561 tattcttttc taacttattt tatattatac tgttttactg aagaactcca ggtgaataaa
     4621 taaatatatg tttatcaaca ttcctagcaa gtatataata ttctatttta ttaatgtttt
     4681 ttgtatttga cttaagcaaa atttaaaata aaattgggag aaatgtgctg ggctacttgt
     4741 a
//
