LOCUS       NM_001044701            6557 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus DENN domain containing 11 (Dennd11), mRNA.
ACCESSION   NM_001044701 XM_001067810 XM_231707
VERSION     NM_001044701.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6557)
  AUTHORS   Zhang,G., Jung,B.P., Ho,W., Jugloff,D.G., Cheung,H.H., Gurd,J.W.,
            Wallace,M.C. and Eubanks,J.H.
  TITLE     Isolation and characterization of LCHN: a novel factor induced by
            transient global ischemia in the adult rat hippocampus
  JOURNAL   J Neurochem 101 (1), 263-273 (2007)
   PUBMED   17394467
  REMARK    GeneRIF: Taken together, these data suggest that LCHN could play a
            role in neuritogenesis, as well as in neuronal recovery and/or
            restructuring in the hippocampus following transient cerebral
            ischemia.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Oct 6, 2022 this sequence version replaced NM_001044701.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.10822.1,
                                           SRR26643297.15865.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               JAXUCZ010000004.1  70195175-70195461   c
            288-387             JAXUCZ010000004.1  70182512-70182611   c
            388-546             JAXUCZ010000004.1  70181539-70181697   c
            547-700             JAXUCZ010000004.1  70177422-70177575   c
            701-839             JAXUCZ010000004.1  70172399-70172537   c
            840-971             JAXUCZ010000004.1  70171628-70171759   c
            972-1122            JAXUCZ010000004.1  70171291-70171441   c
            1123-1191           JAXUCZ010000004.1  70170528-70170596   c
            1192-6557           JAXUCZ010000004.1  70163869-70169234   c
FEATURES             Location/Qualifiers
     source          1..6557
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q23"
     gene            1..6557
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /note="DENN domain containing 11"
                     /db_xref="GeneID:312270"
                     /db_xref="RGD:1563986"
     exon            1..287
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..1387
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /note="protein LCHN"
                     /codon_start=1
                     /product="DENN domain-containing protein 11"
                     /protein_id="NP_001038166.1"
                     /db_xref="GeneID:312270"
                     /db_xref="RGD:1563986"
                     /translation="MVEQGDAAPLLRWAEGPAVSVPQDPALQAGGWVRGGSGGGRVAA
                     EAPRRREPEEPAPPEVLLQPGRLELGDVEEDQVVAVFVVTFDPRSGNMVEWCLPQDID
                     LEGVEFKSMASGSHKVQSDFIYFRKGPFFGLACFANMPVESELERGARMKSVGILSPS
                     YTLLYRYMHFLENQVRHQLEMPGHYSHLAAFYEDKKGVLHAGPGRGGSLPPVYWLPSI
                     HRYMYPEMKITHPAGCMSQFIKFFGEQILILWKFALLRKRILIFSPPPVGVVCYRVYC
                     CCCLANVSLPGIGGTIPESKPFFYVNVADIESLEVEVSYVACTTEKIFEEKRELYDVY
                     VDNQNVKTHHDHLQPLLKLNSADREKYRRLNEQRQMLLYSQEVEGDYSPCEEDLFVLF
                     FLEQNNRIFQTLLEVSASQDKTLTAEHARGMGLDPQGDRSFLMDLLEAYGIDVMLVID
                     NPCCP"
     exon            288..387
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            388..546
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            547..700
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            701..839
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            840..971
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            972..1122
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1191
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..6557
                     /gene="Dennd11"
                     /gene_synonym="LCHN; RGD1563986"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggctccgcct cgcctcgcca tggtggagca gggagacgcg gcgccgcttc tgcgctgggc
       61 cgagggcccc gcggtctctg tgccgcagga ccccgcgttg caggctggag gatgggtccg
      121 gggcggcagt gggggcggcc gagtggccgc ggaagctccc cgaaggcggg aacccgagga
      181 gccagctccc cccgaagtgc tgctgcagcc cgggcgcctg gagctgggcg acgtagagga
      241 ggaccaggtg gtggccgtgt tcgtggtcac cttcgatcct cgctccggaa acatggtaga
      301 atggtgctta cctcaagata ttgaccttga aggtgtcgag ttcaagtcta tggccagtgg
      361 gtcccataag gttcagtctg atttcatcta tttccggaag ggccccttct tcggtctggc
      421 ctgctttgcc aacatgccgg tggagagcga gctggagcgc ggcgcgcgga tgaagtccgt
      481 gggcatcctc tctccgtcct acaccctgct ctaccgctat atgcactttc tggagaacca
      541 ggttcgacac cagctggaga tgccgggaca ttactctcat ctggctgcat tctatgaaga
      601 caagaaaggg gtgctccacg ctggtcccgg gaggggcggc agcttgccac ctgtctactg
      661 gttgccttct attcaccgct acatgtatcc tgagatgaag atcacacacc cggctggctg
      721 catgtctcag tttattaagt tctttggaga acagatcctc attctttgga agttcgcctt
      781 acttcgaaag cgcattctga tattttctcc cccacctgtg ggtgtcgtgt gctatagagt
      841 gtactgttgc tgttgtctgg ccaatgtctc cctgcctggc attgggggca ctatcccaga
      901 atccaaacct ttcttctatg tgaacgtggc tgacattgag agcctggaag ttgaagtgtc
      961 ctatgtagcc tgtaccacag agaagatatt tgaggagaag cgagagctgt acgatgtcta
     1021 tgtggataac cagaatgtaa agacacacca tgaccacctg caacccctgc tgaagctcaa
     1081 cagtgctgac cgggagaagt accgtcggct caatgagcag aggcagatgc tgctgtactc
     1141 ccaggaagtt gaaggagact acagcccttg cgaagaggac ctctttgtgc tgtttttcct
     1201 agagcaaaac aaccggattt ttcagactct gttggaggtg tcagccagcc aagacaaaac
     1261 tctcacagcg gagcatgccc ggggcatggg actggatccc cagggagaca ggagctttct
     1321 catggacctg ctggaggcct atggcatcga cgtgatgcta gtcattgaca acccctgttg
     1381 tccataggta gagtaatagg actggtataa gaactcgtgt ggggtgacag gagcctggcg
     1441 tgcaccccag gccctcagca gcttcagttt taattaagtt gacacaaagg actgtttata
     1501 ctttacaact catgaaattt tttgccattt tcgttctgtt cttcagctct ggggctgggg
     1561 gtgaggctgc ctgggctttt gtagcctttg gttggacatg ggaatctatg gtcttccact
     1621 gctgcttttt ttgggtttag tcttaggagt tctgtgtttc agagtcaaac tctaggatga
     1681 actgttcaga aaacctgtat gtcttcgtcc tttgttgcat acgagaataa gataaccatg
     1741 tgtccttgtg tggccttaga tgttcatctg cctaaaaaca gaaactaatc agatgacctt
     1801 tcaagttcac caagttcaag gagtcaagtt gggatcacct attcatcaga ggacaagtct
     1861 gcaccttctt ggttcgctgg agtagaggga ccacgaagac gaagaaaaaa agtgtctctg
     1921 atagaatggc agggaaagaa tccttgaaat gcttcctaaa ataagggaat gtgagttaca
     1981 gcatacaccc caccccgcct ccccaccacc ccagtcctct tggtcagtgc tgaggggtgg
     2041 tgctggccct gagcttacga gcaaattcac ttgtcctcca gtctctctta agcctgggaa
     2101 tcctctggga ctaacaggtc caaataggta agggaggaaa tctccagttt ctctaagaac
     2161 tctgtggagg gatggtacac agcagacact tctgatgaat tctgaaaagt agccagggtc
     2221 caagctgctt gattcgggtc tcttcaccaa tctgaaactc ccacagccat ctcggaagca
     2281 gagacagcat tccttaggct aagcagttgg atccacagac ctaacagatt tgacagggaa
     2341 accataatgg tgcctcccat acaagataat cattgaaatc ccagactaat tccgtgcttg
     2401 gtctgcaatg ggacccacag tcactctgtt ctttggggct gcgattcttt ggacttatgg
     2461 actaggcggg agggcagttg ttaaccgtat tcagaaagcc atgtgagtag ctagctaacc
     2521 agccatcaga catccaggtc tgtagctaaa gagcagccag gctgatggcc acagaggagg
     2581 actcctatct cacgtttagg ttcttgaggc tagcccaggc atctccattg tagctccagg
     2641 agtgaagagt tcggtgtgtg tgaaaatgca cagacacaga tgagtcaggg tagcatcttt
     2701 tctgtaaata tatcagtaag tctaggcatt gacataaact gtcagctaat tgatctttct
     2761 cctctgcagt gggggttagc catcattcca gcaacatgat gtttacaaaa aacacagctg
     2821 tgcttagtgg ctgactttgc acctacttta ccttacagct gccttctcct cttgctgagc
     2881 ggggtcacct gatgccgatg gagcaacagt tccattggtc tctgaagctc atagttgggg
     2941 gtggacagcc agagacggga gcaggaggaa aagcaggctg ctgcttctga ggagtctcta
     3001 gaattcagtc ttgaagagcc tatttctgag aaactcccta gagccttctg ggtgccagca
     3061 ctgcttcctg tgctgttgag gcacgagcgt gctgatgtaa aggtagcaag ggtgagagag
     3121 gctgtccttt gttaacctct ccttcggtcc tcccctacct ggccggcttc tcacagagcc
     3181 agaccagagc acaggcgtct gtgtggccga ctgtgtgtac gtcagcaccc cttgcaccct
     3241 ttgctccatg tatcagctgt ggagtacgcc ttgaaaaagt gagtccagtc cacatcacta
     3301 tgaagtcaca ccaggctgct cccgcagtgg cagtgagcag atgcaagcct gcatagtctg
     3361 ctgtgagtct tctataaagg gaagtagttt gtgcagaact atataggaac cgccccctac
     3421 agtgatggct gaagctagta gtcagaggat acgcttgccc atctctcttg aaatactttc
     3481 taaaaaggca gctggcttta tttggaagaa gacagttcat gtccctcata tctttctgac
     3541 ttttagcaga aataggcgtt tctttcttac cactggcctc taggaagagg gctaaaaact
     3601 cggatgtggg tcctgccatt ctgctggtgg ctctcatcag acccctgcct gagctggcag
     3661 agcccttctg gggagtatta atccccatct gtaccatgct gggagccatg tgctaaccaa
     3721 aaagcacttg ctgttgttca ttgctggcta ctcagtcatt tttaaggtag gagaaatttc
     3781 caatgacaat aatcctcagg gtcttggggg ttttgggttt gtggacacca atgttaagta
     3841 taacatactg agtataacaa aagcctctta aagtggatgt tttcagtttt gtcggcagat
     3901 ggtaatactc agctagttgc catctggctc aggactcttt cctcagaagc agtaaaaata
     3961 gcagagctta tctcctacca atctataaaa gaaggccaag tcattgcctc gtattagtgt
     4021 tgactttaaa cattcagcct tccctgtgcc gggcgtgcat ccaggccatt gccggcgtcc
     4081 tacctggggc ccatatggtc ctatcagtta agagtacaat gtgacaggag gcatttgcct
     4141 tgcactcctc ccacacctcc cacacctccc acacactctg gcttccaaag agaagctggt
     4201 ttcattgctg ggatagaagt taggatagga acttgaaact gtaacttacc ttgctggaac
     4261 ccatggaaag gtgagagtga cactcagata caatagggcc agatgcttca tgggaaggtt
     4321 catttacaca attacctaat atattttagc tagatgacaa aggtaaatta gacagtcgtt
     4381 aactgctgtc ttcattctgg cggcgagggg cggaacctcc tgatctgagg cactgaaagc
     4441 ctatcaatac aggggaaggt gagacggact tgtccttcca ctgaagcttc tggggaaact
     4501 tctctaagag tggttgtgga tcagctggtg gcaaaagcca gcctcctaga gatgcagggc
     4561 cttgggaatg gtcttttttt tttttttctc ccttaaactg cacagccaga gtgggttgag
     4621 atgctttctc caagttcaga gtggtagata gatggataga cagacagata gatagatagg
     4681 taggtaggta ggtaggtagt ccttgcagag gtagagaaag ggatacaggc gtgggtgaac
     4741 agaacataat gctggatctc acagtgaaca ctttattatg agaagtttgg aaactggcaa
     4801 gagcatctat aggaagacac aacaggccct ccggggctgc cgtcctcccc ttaggcttcc
     4861 aggctaatag gctacgattc tgagagctgt ccagccctcc catctctccc tcatacccat
     4921 ggtgaggctc ctgaaggctt acctcagcag gcccagtttc atcccttccc atttcatgaa
     4981 aacccttttc agtcaggtag gggaagggga gaagttaagg cctaacccaa gtcctgggct
     5041 ttgactacta ctccacttta ttgctaatat acctctgttc ccaggagtac tgaagtgccc
     5101 agtgttgtga gggaaagacg gtgagttaag gcaatgcttt tcctatgaga aatggaagtt
     5161 tattttttat accagtgtta ctgagtggtg aattacgtac tgacacattg aaacagaaag
     5221 gaattgcaaa gttctaatct aaaaagcaat gggcagcttt gtagtttaat agcagtggag
     5281 acccttagac atgtcatgtc tgtgacagtg ttttggagca tgagcacatg ctctctgctg
     5341 tattatttca acagcattac agaagatagt caactggccc agcaagggtg agagggacag
     5401 tggccttggg ggaagctgca gaacagaaga gcacgaatag cctttcagtg accattcccc
     5461 tcttgatcaa gggggagagt gagagagggg aatggcaggc agtctgctaa ctagcacttt
     5521 aattcacttt agtcctggaa gtggggtgaa aagtttaaat gtagtaaagg aacgggactt
     5581 ttctggtgct atctagagaa acgaagatgg gatgaataaa gctcctttta gagcttattc
     5641 tagaatgtca gcatggcgct ggctctcaac catgctgact taaactctga caggtttaca
     5701 gcagaggatt tgtttgcatt tgcagcaggt gcctgttttg tctgctgagt ttactttcct
     5761 tcctaatgat actaggactc actggagtgg ggttttataa attgtgaata gatgggactg
     5821 caaagtgaaa agcccataca gagcaaacat atgtaattga cgttgtatct gggtcaatta
     5881 agcaaggata tataaaagtt aggcaaaccc aaagtttact ttccttgccc atcagaaatg
     5941 ccttcagcca tcagaaatgg gggattctgt cctcctgaac atgaactagc atgagtggct
     6001 accaggcttc gggataggta aacaaaacca actaaaccaa cttcctttat ttgcccaaaa
     6061 cttgttggat aaatttttgt ataagtctgg aatataatcc ttcctgaaaa aaaaaatcat
     6121 ggtaaccaag gaaatatgct ttcctagttt tttttaaaca tagtgtccct gctgccttaa
     6181 atgtaaaaac ctattttgag taataacccc agcctaagag ttatagcaat aaatgaaccc
     6241 gaatctattt ttctttcaag tctttacctc atgtgacaaa gtcagaagga taattggtaa
     6301 gttttgctct gggtactact gcaaaccgat gtatcctttc tctgtgtctt caatggagta
     6361 ttatttacag acctgaagga agctgggctt aaccccaagg ctaagtgtaa atgtttcttg
     6421 aattgattct ttctgtggta caagttaaca cctgtgtata tcatatctgt atatatctga
     6481 accaagttat gtgcagaggt tgataataac tatatttaca aaaaattttt acaattaaac
     6541 ttcacatttt aacatga
//
