LOCUS       NM_001398802            2305 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus DENN domain containing 10 (Dennd10), transcript
            variant 1, mRNA.
ACCESSION   NM_001398802 XM_006231682
VERSION     NM_001398802.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2305)
  AUTHORS   Zhang,J., Zhang,K., Qi,L., Hu,Q., Shen,Z., Liu,B., Deng,J.,
            Zhang,C. and Zhang,Y.
  TITLE     DENN domain-containing protein FAM45A regulates the homeostasis of
            late/multivesicular endosomes
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1866 (5), 916-929 (2019)
   PUBMED   30771381
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 23, 2021 this sequence version replaced XM_006231682.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643291.5191.1,
                                           SRR26643296.4885.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                JAXUCZ010000001.1  269937023-269937105
            84-280              JAXUCZ010000001.1  269939727-269939923
            281-360             JAXUCZ010000001.1  269943017-269943096
            361-509             JAXUCZ010000001.1  269945991-269946139
            510-621             JAXUCZ010000001.1  269946882-269946993
            622-722             JAXUCZ010000001.1  269950997-269951097
            723-830             JAXUCZ010000001.1  269955680-269955787
            831-925             JAXUCZ010000001.1  269956941-269957035
            926-2305            JAXUCZ010000001.1  269959127-269960506
FEATURES             Location/Qualifiers
     source          1..2305
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..2305
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /note="DENN domain containing 10"
                     /db_xref="GeneID:308009"
                     /db_xref="RGD:1308326"
     exon            1..83
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1099
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /note="isoform 1 is encoded by transcript variant 1;
                     family with sequence similarity 45, member A; DENN
                     domain-containing protein 10"
                     /codon_start=1
                     /product="DENN domain-containing protein 10 isoform 1"
                     /protein_id="NP_001385731.1"
                     /db_xref="GeneID:308009"
                     /db_xref="RGD:1308326"
                     /translation="MAAVVAMDTQLMLGVGLIEKDTNGEVLWVWCYPSTTASLRNLLL
                     RKCCLTDENKLLHPFVFGQYRRTWFYVTTVEVPDSSVLKKVTHFSIVLTAKDFNPEKY
                     AAFTRILCRIYLKYGSPVKMMESYIAVLTKGICQSEENGSFLSRDFDGRKAYLAGSIK
                     DIVSQFGMETIILHTALMLKKRIVVYHPKIEAVQEFTRTLPALVWHRQDWSILHSYMH
                     LHAEELEGLQMCTGYIAGFVDLEVSNRPDLYDVFVNLADSEIIIAPLAKEAMTMGKLH
                     KEIGQLIVQSAEDPEKSDSQVIQDIALKTKEIFTHLAPFSEASDAGKVFLNVEALKQK
                     RFPPATENFLYHLAAAEQMLKV"
     exon            84..280
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            281..360
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            361..509
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            510..621
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            622..722
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            723..830
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            831..925
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
     exon            926..2305
                     /gene="Dennd10"
                     /gene_synonym="Fam45a; RGD1308326"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtgcggag ccggggaagc ggcggaagat ggctgcagtt gtagcaatgg acacccagct
       61 gatgctcgga gtcgggctga tcgaaaagga cactaatgga gaagttctgt gggtgtggtg
      121 ttatccttcc acgacagcct cactaaggaa tctgctgctc cgaaaatgct gcctaactga
      181 tgaaaacaaa cttctccacc cttttgtctt tggtcagtac agaagaacat ggttttatgt
      241 cactacagtt gaagttccag attcttcagt tttgaaaaag gtgactcatt tttctattgt
      301 tctgaccgcc aaagatttta acccagagaa atatgccgcc ttcactagga tattgtgtag
      361 aatatatttg aaatatggaa gtccagttaa aatgatggaa agttacattg cagttctcac
      421 caaggggatc tgccagagtg aagaaaatgg ctccttcctt agcagagact ttgatggtcg
      481 aaaggcgtac ctcgccggct ccatcaaaga cattgtatct caatttggaa tggaaactat
      541 tatcttacac acagcgttga tgctgaaaaa acgaattgtt gtctatcacc ccaaaataga
      601 agctgttcag gagttcacca ggactctgcc tgccctggtg tggcatcgac aggattggtc
      661 catcctgcat tcttacatgc accttcatgc tgaggaactg gaaggcctac agatgtgcac
      721 aggctacatt gctggctttg tagatttgga ggtgagcaac agaccagacc tctacgacgt
      781 gtttgtgaat ctggcagaca gtgagatcat catcgctcca cttgcaaaag aggccatgac
      841 aatgggcaaa ctgcataaag agattggtca actaattgtg cagtctgcag aagacccaga
      901 gaagtcagac agccaggtta tacaggacat tgccctaaaa acaaaagaaa tcttcaccca
      961 cctggcacca ttctcagaag cgtcagatgc ggggaaggtc ttcctcaatg ttgaggcact
     1021 gaagcagaag cgatttccac ccgccacaga aaacttcctg tatcatctag cggccgctga
     1081 acagatgctg aaggtctgat ggttcacaac attttgctgt ggcccctaca gaacttccct
     1141 tttattccta gtacctatcg acatgtacag tattggaatt ataggaatgc tctattttta
     1201 atgatttatt tccaaatagt gagagcttag gtgagagcac ataaaaacga ttgtgatttt
     1261 ctccctgtca atttgatcca gtacagtgtt ttaattttaa ttgctgtctt aatggtagga
     1321 gccacataga tcagcacatg caaaccttca ttgttcattc ctatttagtc tcactgtaac
     1381 cataaacata agctcgtttt cagaaagccg tctcaaagtt tgctttttta ttcttctaga
     1441 aaaaaaactt gaattcctca tgagagagtt tgctttttga gcctaactgc tatgttttct
     1501 tcagaatttt ctagaaggtc attcaaggga tactacagtt gcactttctt gtaaaagaaa
     1561 atattttggg gcctttgaaa tttttgccta ttttatgagg gtttttcata cttgagcaga
     1621 caactccaac aacccttaca ctgccctaga cataagcact caacaaacat cagtcattag
     1681 tgctcttgga ctcactcctg ctacagtgtc tttggaaaag aggccagtcc ccaacaaaga
     1741 aacccctttt aagtgtaagc atgtctaaga aaaagtacct tggttgtttt tgtttacaat
     1801 gctggagcta gaacctgggg ccttgatgtg ccaggcattg ctttcccacc aaattaaacc
     1861 cccagcccaa taatgctttc agatattggt aaaggaacat gagaaccaat tgcagaggcc
     1921 aaaactagac agtgtcttca agtgactgca gtaaagggat ttggccacat catcaaggac
     1981 actgttacta ctctctctta atttgagatg ttaaaattgc caaataagca cgaatgtatc
     2041 aattatgcat tccttatgtc tacttacatt atttatgaaa ggccaccttt cttagtatag
     2101 ttgcagagca ttcaaacctt accaggaaac atgtttgcaa aaactttatg ttgggtattt
     2161 tttttaacct tattcttaga catttaagta aaaataaaaa aatagccttt ccttcttgtc
     2221 tttgagtgga aacagggagg acttgacata cgttgtttac tggagctaac aactgaagat
     2281 taaatttgca ctttataaaa agagc
//
