LOCUS       NM_001004255            2575 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DEK proto-oncogene (Dek), mRNA.
ACCESSION   NM_001004255 XM_225209
VERSION     NM_001004255.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2575)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2575)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2575)
  AUTHORS   Cheung,T.H., Quach,N.L., Charville,G.W., Liu,L., Park,L.,
            Edalati,A., Yoo,B., Hoang,P. and Rando,T.A.
  TITLE     Maintenance of muscle stem-cell quiescence by microRNA-489
  JOURNAL   Nature 482 (7386), 524-528 (2012)
   PUBMED   22358842
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2575)
  AUTHORS   Kavanaugh,G.M., Wise-Draper,T.M., Morreale,R.J., Morrison,M.A.,
            Gole,B., Schwemberger,S., Tichy,E.D., Lu,L., Babcock,G.F.,
            Wells,J.M., Drissi,R., Bissler,J.J., Stambrook,P.J.,
            Andreassen,P.R., Wiesmuller,L. and Wells,S.I.
  TITLE     The human DEK oncogene regulates DNA damage response signaling and
            repair
  JOURNAL   Nucleic Acids Res 39 (17), 7465-7476 (2011)
   PUBMED   21653549
REFERENCE   5  (bases 1 to 2575)
  AUTHORS   Hollenbach,A.D., McPherson,C.J., Mientjes,E.J., Iyengar,R. and
            Grosveld,G.
  TITLE     Daxx and histone deacetylase II associate with chromatin through an
            interaction with core histones and the chromatin-associated protein
            Dek
  JOURNAL   J Cell Sci 115 (Pt 16), 3319-3330 (2002)
   PUBMED   12140263
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079344.1.
            
            On Sep 10, 2004 this sequence version replaced XM_225209.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079344.1, SRR8487231.33871.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2575
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..2575
                     /gene="Dek"
                     /note="DEK proto-oncogene"
                     /db_xref="GeneID:306817"
                     /db_xref="RGD:1303246"
     exon            1..96
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            97..256
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..1242
                     /gene="Dek"
                     /note="DEK oncogene (DNA binding)"
                     /codon_start=1
                     /product="protein DEK"
                     /protein_id="NP_001004255.1"
                     /db_xref="GeneID:306817"
                     /db_xref="RGD:1303246"
                     /translation="MSAAAAPAAEGEDTPTPPASEKEPEMPGPREESEEEEEEDDDDE
                     DEEEEKEKSLIVEGKREKRKVERLTMQVSSLQREPFTIAQGKGQKLCEIERIHFFLSK
                     KKTDELRNLHKLLYNRPGTVSSLKKNVGQFSGFPFEKGSTQYKKKEEMLKKYRNAMLK
                     SICEVLDLERSGVNSELVKRILNFLMHPKPSGKPLPKSKKSSSKGSKKERNSSGTTRK
                     SKQTKCPEILSDESSSDEDEKKNKDESSEDEEKESEEEQPPKKTSKKEKAKQKATTKS
                     KKSVKSANVKKADSSTTKKNQNSSKKESGSEDSSDDEPLIKKLKKPPTDEELKETVKK
                     LLADANLEEVTMKQICKEVYENYPAYDLTERKDFIKTTVKELIS"
     exon            257..358
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            359..468
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            469..563
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            564..684
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            685..873
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            874..1012
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            1013..1161
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1230
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..2553
                     /gene="Dek"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttgattctg aggaaccgag agcgagcgcg cggcttcgcg aggacctcgg cccgcgcgcc
       61 ttccactcag cggcggcctt ctcgtgcgca cccgcggctc ccagcatgtc ggcggcggca
      121 gcccccgctg cggagggaga ggacaccccc acgccgcccg cgtccgagaa ggaacctgag
      181 atgccgggtc ccagggagga gagtgaggag gaagaggagg aggacgacga cgatgaggat
      241 gaggaggaag aaaaagaaaa gagccttatc gtggagggca agagagagaa gaggaaagta
      301 gagaggctga cgatgcaggt gtcttcctta cagagagagc cgttcacaat cgcacaaggg
      361 aagggtcaga aactttgtga aattgaaagg atacatttct ttctgagtaa gaaaaaaaca
      421 gatgaactta gaaatctaca caaactgctt tacaacaggc cgggcacagt gtcctctttg
      481 aagaagaatg tgggtcagtt cagtggcttt ccatttgaaa aaggcagtac ccagtataaa
      541 aagaaggaag aaatgttgaa aaagtataga aacgccatgt taaagagcat ctgtgaggtt
      601 cttgatctag agaggtcagg tgtgaacagt gaactagtga agaggatctt gaatttctta
      661 atgcatccaa agccttctgg caaaccattg ccaaaatcca aaaaatcttc cagcaaaggt
      721 agtaaaaagg aacggaacag ttctggaacg acaaggaagt caaagcaaac taaatgtcct
      781 gaaattctgt cagatgagtc tagtagtgat gaagatgaga agaaaaacaa ggacgagtct
      841 tcagaagatg aagagaaaga aagtgaagag gagcaaccac caaaaaagac atctaaaaaa
      901 gaaaaagcaa aacagaaagc taccactaaa agtaaaaaat ctgtgaagag tgctaatgtt
      961 aagaaggcgg acagcagcac caccaagaag aaccaaaaca gttccaaaaa agagtctgga
     1021 tctgaagata gttctgatga tgaaccttta attaaaaaat tgaaaaagcc acctacagat
     1081 gaagaactaa aggagactgt gaagaagtta ctggctgatg cgaacctgga agaagtcaca
     1141 atgaagcaga tttgcaaaga ggtatatgaa aattatcctg cgtatgattt aactgagagg
     1201 aaagatttca ttaaaacgac tgtaaaagag ctaatctctt gagatagagg acagatggct
     1261 tgttctcaga ttagaagatc tgatttatac cagcaaagag aatgtattct tttttaagtc
     1321 tattgttggt agaacttgct gctgactctt ttgcgtgtta catatatttg agcttgtttt
     1381 aaattgcatt ttctcgcagt tttcagttta aatcttgcat ggccgaaatt gttccttgct
     1441 ttttatagtt gtacattttg ggtttcttta ttgtaaggtc atagattcct gaactattgt
     1501 gaattttagt gaacttaatg ttagcttgct taagacatac ttttaatcaa agcaaaaact
     1561 attataacca gcatttatat gtgcaaagac gactgcagta tttagcatat ggatattttg
     1621 aacacatctt ctgtcagtgt gggacacggc ggcagtctgt tcatcagggt ggagcacagc
     1681 tgtgcagacg accgagctgg aactttctct gcatgtgtat atatctcaag ttgttggcat
     1741 gacagaagtg acagatgtta tttttgtatt ttttaaaacc aatttgttgt atataatttt
     1801 ttttatttct tttgtgcaaa tcaatttttt aaatcttgtg tctttaaact tgtaactaaa
     1861 cgtcagtgtt catccaggca gcaatgacag aacagttcag tgatgatgac actgaaagga
     1921 ctgttgagtt ctgctttgcc ctgaaagtgt catcagtgtg gttgtgttaa aactttaagt
     1981 gtcatagaaa ttttatgagg ataaacacat cacagcttca aactgggaaa gagtaagcac
     2041 acatagctta tgtatcagtg aactgacagt agcaaacctc tgaccatata aaagatacag
     2101 gaaacctggc taccttcata attatgataa aagtatctgg gtaaggccag agttggtgtg
     2161 gacaacatag gtctctaaag tatatcaaaa accatacatt taatattaaa gtattataga
     2221 atcaaggcta tttgatttta aattttggtc aatcaagatt ttaaggtgat gaaacatgga
     2281 gtgcccctga atttaaattt tgactgtcct aataacctat ttctgaatta taacatgctg
     2341 cttgacagag tgacatttga tgtaccgact gagtgtttaa tcttccacat cagagatcag
     2401 atttgagcat taacaggtat attttcacat acttgacttc aacatgctta gagtgatatg
     2461 gaacaggcaa ctaagggggg actaaaaagt tgacctttgt cataaatctt cgcaataaag
     2521 aataaatcaa tgttttaagt ttcttgtatt taaaaaaaaa aaaaaaaaaa aaaaa
//
