LOCUS       NP_001032617              70 aa            linear   ROD 01-MAY-2025
DEFINITION  beta-defensin 43 precursor [Rattus norvegicus].
ACCESSION   NP_001032617
VERSION     NP_001032617.1
DBSOURCE    REFSEQ: accession NM_001037528.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 70)
  AUTHORS   Kim,J.H., Kim,K.H., Kim,H.J., Lee,J. and Myung,S.C.
  TITLE     Expression of Beta-Defensin 131 Promotes an Innate Immune Response
            in Human Prostate Epithelial Cells
  JOURNAL   PLoS One 10 (12), e0144776 (2015)
   PUBMED   26649771
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 70)
  AUTHORS   Patil,A.A., Cai,Y., Sang,Y., Blecha,F. and Zhang,G.
  TITLE     Cross-species analysis of the mammalian beta-defensin gene family:
            presence of syntenic gene clusters and preferential expression in
            the male reproductive tract
  JOURNAL   Physiol Genomics 23 (1), 5-17 (2005)
   PUBMED   16033865
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY621370.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..70
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     Protein         1..70
                     /product="beta-defensin 43 precursor"
                     /note="beta-defensin 43"
                     /calculated_mol_wt=5954
     sig_peptide     1..22
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=2393
     mat_peptide     23..70
                     /product="Beta-defensin 43. /id=PRO_0000352717"
                     /note="propagated from UniProtKB/Swiss-Prot (Q32ZF3.1)"
                     /calculated_mol_wt=5954
     Region          28..57
                     /region_name="Defensin_beta_2"
                     /note="Beta defensin; pfam13841"
                     /db_xref="CDD:463997"
     CDS             1..70
                     /gene="Defb43"
                     /gene_synonym="BD-43"
                     /coded_by="NM_001037528.2:121..333"
                     /db_xref="GeneID:641651"
                     /db_xref="RGD:1566384"
ORIGIN      
        1 mrlllsilgv ltllsilpla rsflanqecf seyrhcrmkc kaneyairyc adwticcrvk
       61 kreakkkimw
//
