LOCUS       NP_001178646             630 aa            linear   ROD 31-MAR-2024
DEFINITION  differentially expressed in FDCP 6 homolog [Rattus norvegicus].
ACCESSION   NP_001178646 XP_228031
VERSION     NP_001178646.1
DBSOURCE    REFSEQ: accession NM_001191717.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 630)
  AUTHORS   Liang,Y., Cucchetti,M., Roncagalli,R., Yokosuka,T., Malzac,A.,
            Bertosio,E., Imbert,J., Nijman,I.J., Suchanek,M., Saito,T.,
            Wulfing,C., Malissen,B. and Malissen,M.
  TITLE     The lymphoid lineage-specific actin-uncapping protein Rltpr is
            essential for costimulation via CD28 and the development of
            regulatory T cells
  JOURNAL   Nat Immunol 14 (8), 858-866 (2013)
   PUBMED   23793062
REFERENCE   2  (residues 1 to 630)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Jul 17, 2010 this sequence version replaced XP_228031.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.2530070.1,
                                           SRR26643429.57153.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     Protein         1..630
                     /product="differentially expressed in FDCP 6 homolog"
                     /calculated_mol_wt=73435
     Region          210..319
                     /region_name="PH_SWAP-70"
                     /note="Switch-associated protein-70 Pleckstrin homology
                     (PH) domain; cd13273"
                     /db_xref="CDD:270092"
     Region          <296..>536
                     /region_name="Smc"
                     /note="Chromosome segregation ATPase Smc [Cell cycle
                     control, cell division, chromosome partitioning]; COG1196"
                     /db_xref="CDD:440809"
     CDS             1..630
                     /gene="Def6"
                     /coded_by="NM_001191717.2:36..1928"
                     /db_xref="GeneID:309642"
                     /db_xref="RGD:1307945"
ORIGIN      
        1 malrkellks iwyaftaldv eksgkvsksq lkvlshnlyt vlhiphdpva leehfrdddd
       61 gpvssqgymp ylnkyildkv eegafvkehf delcwtltak knyrvegngn sllsnqdafr
      121 lwclfnflse dkyplimvpd eveyllkkll gslslemglg eleellaqda qsaqtsggls
      181 vwqflelfns grclrgvgqd slsmaiqevy qeliqdvlkq gylwkrghlr rnwterwfql
      241 qpsclcyfgs eeckekrgti pldahccvev lpdregkrcm fcvktasrty emsasdtrqr
      301 qewtaaiqta irlqaegkts lhkdlkqkrr eqreqrerrr aakeeellrl qqlqeekerk
      361 lqelellqea qrqaerllqe eeerrrsqhr elqqalegql reaeqarasm qaemelkkee
      421 aarqrqriae leemqerlqe alqlevkarr deeavrlaqt rlleeeeekl kqlmhlkeeq
      481 eryieraqqe kqelqqemal qsrslqqaqq qleevrqnrq radedveaaq rklrqastnv
      541 khwnvqmnrl mhpiepgdkr pttsssftgf qapplarrds slkrltrwgs qgnrtlsans
      601 seqkslnggd etpilalasq eekldaapen
//
