LOCUS       NM_053525               2175 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DExD-box helicase 52 (Ddx52), mRNA.
ACCESSION   NM_053525
VERSION     NM_053525.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2175)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2175)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2175)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 2175)
  AUTHORS   Saad,Y., Garrett,M.R., Manickavasagam,E., Yerga-Woolwine,S.,
            Farms,P., Radecki,T. and Joe,B.
  TITLE     Fine-mapping and comprehensive transcript analysis reveals
            nonsynonymous variants within a novel 1.17 Mb blood pressure QTL
            region on rat chromosome 10
  JOURNAL   Genomics 89 (3), 343-353 (2007)
   PUBMED   17218081
REFERENCE   5  (bases 1 to 2175)
  AUTHORS   Venema,J., Bousquet-Antonelli,C., Gelugne,J.P.,
            Caizergues-Ferrer,M. and Tollervey,D.
  TITLE     Rok1p is a putative RNA helicase required for rRNA processing
  JOURNAL   Mol Cell Biol 17 (6), 3398-3407 (1997)
   PUBMED   9154839
REFERENCE   6  (bases 1 to 2175)
  AUTHORS   Murakami,M., Kudo,I., Fujimori,Y., Suga,H. and Inoue,K.
  TITLE     Group II phospholipase A2 inhibitors suppressed
            lysophosphatidylserine-dependent degranulation of rat peritoneal
            mast cells
  JOURNAL   Biochem Biophys Res Commun 181 (2), 714-721 (1991)
   PUBMED   1721808
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB055628.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB055628.1, BC089107.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132271, SAMD00132274
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2175
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q26"
     gene            1..2175
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /note="DExD-box helicase 52"
                     /db_xref="GeneID:85432"
                     /db_xref="RGD:621743"
     exon            1..93
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     CDS             7..1803
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /EC_number="3.6.4.13"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; DEAD box
                     protein 52; rROK1L; ATP-dependent, RNA helicase; DEAD-box
                     helicase 52"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DDX52"
                     /protein_id="NP_445977.1"
                     /db_xref="GeneID:85432"
                     /db_xref="RGD:621743"
                     /translation="MDSYDLFRRLGAGAKFDVKRFSADATRFQVGKRKFGSDSSETVK
                     GLDFFGNKKSVSDECGGLQTQQELQNEETTEGGLLERSKEPKKKKRKKMTADVPAQED
                     LDGTIQWTSSVEAKLQDKKANGEKKLTSEKLEHLRKEKINFFRNKHKIHVQGTDLPDP
                     IATFQQLDQEYKISPRLLQNILDAGFQVPTPIQMQAIPVMLHGRELLASAPTGSGKTL
                     AFSIPILMQLKQPTNKGFRALVISPTRELASQIHRELIKISEGTGFRIHMIHKAAIAA
                     KKFGPKSSKKFDILVTTPNRLIYLLKQEPPGIDLTSVEWLVVDESDKLFEDGKTGFRD
                     QLASIFLACTSPKVRRAMFSATFAYDVEQWCKLNLDNIVSVSIGARNSAVETVEQELL
                     FVGSETGKLLAMRELVKKGFNPPVLVFVQSIERAKELFHELIYEGINVDVIHAERTQQ
                     QRDNTVHSFRAGKIWVLICTALLARGIDFKGVNLVINYDFPTSSVEYIHRIGRTGRAG
                     NRGKAVTFFTEDDKPLLRSVANVIQQAGCPVPEYIKGFQKLLSKQKKKMIKKPLERES
                     ISTTPKYFLEQAKQKKVAGQNSKKKETLKGKS"
     exon            94..292
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            293..426
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            427..612
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            613..756
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            757..868
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            869..941
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            942..1145
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1146..1236
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1237..1359
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1510
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1511..1586
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1587..1658
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1745
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
     exon            1746..2159
                     /gene="Ddx52"
                     /gene_synonym="Rok1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaagatgg attcctacga tctgtttcgc cggctcggag ccggcgccaa gttcgacgtg
       61 aagcggttct cagcagacgc tactcgattc caggtaggaa aaagaaaatt cggttctgat
      121 tcttcagaga ccgtgaaggg actagacttc ttcggaaaca agaaatctgt ctcagatgag
      181 tgtggaggat tacaaacaca gcaggagctc caaaatgagg agacaacaga agggggcctg
      241 ctggaaagga gtaaggagcc gaagaagaaa aagagaaaga agatgactgc agacgttcct
      301 gctcaagaag accttgacgg gacgatacag tggacatcct ctgtggaagc aaagcttcaa
      361 gataaaaaag ccaatggaga gaagaaatta acttcagaaa agttggagca tctcagaaag
      421 gaaaagatca acttctttcg gaacaaacac aagatacatg tccaaggaac tgatcttcct
      481 gacccaattg ctacatttca gcaacttgat caagaatata agatcagtcc tcgattgctc
      541 cagaatattc tagatgcagg cttccaggtg cccacaccaa ttcagatgca agccattcca
      601 gttatgctgc atggtcggga acttctggct tctgctccta ctggatccgg gaagacgttg
      661 gcatttagca tccccatttt aatgcagctg aaacaaccca caaataaagg ctttagagcc
      721 ctggttatat ccccaacccg agaacttgcc agccagattc acagagaatt aattaaaata
      781 tctgagggta caggattcag gatacatatg atccacaaag ctgcaatagc agctaagaaa
      841 tttggaccta aatcatctaa gaagtttgat atccttgtga ccactccaaa tcgactgatc
      901 tacttgctga agcaggagcc gccagggata gacctaacaa gtgttgagtg gctggtagta
      961 gatgagtcgg acaaactgtt cgaagatggc aaaactgggt ttcgagacca gctggcttcc
     1021 attttcctgg cctgcacatc ccccaaggtc agaagagcaa tgttcagtgc aactttcgca
     1081 tatgacgttg agcagtggtg caagctcaac ctggataaca tagtttccgt atccattgga
     1141 gcaaggaatt ctgcagttga aactgttgaa caagagcttc tgtttgttgg atcggagact
     1201 ggaaaacttc tggccatgag agaacttgtt aaaaaaggct tcaatccacc tgtccttgtt
     1261 tttgttcagt ccattgaaag ggctaaagag cttttccatg agctcatata tgaaggtatt
     1321 aatgtggacg tcattcatgc agaaagaaca cagcagcaga gagataacac agtccacagc
     1381 ttcagagcag gaaaaatctg ggttcttatt tgtacagcct tgcttgcaag agggattgac
     1441 tttaaaggtg taaacctggt catcaattat gatttcccaa ccagctcagt ggaatacatc
     1501 cataggatag gtcgaactgg aagagcaggg aataggggaa aggctgttac atttttcacc
     1561 gaagatgata aaccattact aagaagtgtt gccaatgtta ttcagcaggc tggttgtcct
     1621 gtacctgaat acatcaaagg tttccagaaa ctactgagca aacaaaagaa aaaaatgatt
     1681 aagaagccat tggaaaggga gagcattagt acaactccaa aatatttctt agagcaagct
     1741 aaacagaaaa aggttgctgg ccaaaacagc aagaagaaag aaactcttaa aggaaaaagt
     1801 taaaaataaa caccctgcag tgcaatttat gaactcggca tgaattctca tggagtacct
     1861 acaactatct ttaccaaaca ttttaagtca acaagggtat gagagaacaa aatggtcctg
     1921 atttagtgac ttgtcaagct tcactttgta aatgggattt atacaatgga aataacatgc
     1981 attgacattt ctgcctgaat ctagagagct acttcttata gaagaacaaa gctgatgcta
     2041 aaataacacc catgtggtga actcttaagg attttgccct tcaagtgtga aggaaagtgt
     2101 gatgcatgct gtggagaggc atctggaaca gaattttaaa ataaaacctt gagctcgcaa
     2161 aaaaaaaaaa aaaaa
//
