LOCUS       NP_001388096             635 aa            linear   ROD 03-APR-2024
DEFINITION  ATP-dependent RNA helicase DDX51 [Rattus norvegicus].
ACCESSION   NP_001388096 XP_006249623
VERSION     NP_001388096.1
DBSOURCE    REFSEQ: accession NM_001401167.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 635)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (residues 1 to 635)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (residues 1 to 635)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Feb 3, 2022 this sequence version replaced XP_006249623.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.35719.1,
                                           SRR26643298.81467.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     Protein         1..635
                     /product="ATP-dependent RNA helicase DDX51"
                     /EC_number="3.6.1.-"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 51"
                     /calculated_mol_wt=70019
     Region          177..421
                     /region_name="DEADc_DDX51"
                     /note="DEAD-box helicase domain of DEAD box protein 51;
                     cd17956"
                     /db_xref="CDD:350714"
     Site            order(185..186,188..190,193,225..232)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350714"
     Region          448..578
                     /region_name="SF2_C_DEAD"
                     /note="C-terminal helicase domain of the DEAD box
                     helicases; cd18787"
                     /db_xref="CDD:350174"
     Site            order(537,539,564,567..568)
                     /site_type="other"
                     /note="ATP binding site [chemical binding]"
                     /db_xref="CDD:350174"
     CDS             1..635
                     /gene="Ddx51"
                     /coded_by="NM_001401167.1:21..1928"
                     /db_xref="GeneID:304570"
                     /db_xref="RGD:1309580"
ORIGIN      
        1 malfhiarya gpeaaglgdt eaeaggrarv llerlqnrar ereqrqpele stgtaaeapv
       61 rrrrrprrrr gvsgsvaekp eaprakrqkv eddvdagrge etpeelsesa edpgespqed
      121 vqrppapgrv lgdfarkkvp kvqpflpawl akpscvkksv tedltpiedi pevhpdlqkq
      181 lrangissyf pvqaavipal lesadngflv grggyqpsdl cvsaptgsgk tlafvipvvq
      241 allhrvvchi ralvvlptke laqqvskvfn iytdttplrv alvtgqksla keqeslvqkt
      301 adgfccladi vvatpgrlvd hidqtpgfsl qqlrfliide adrmidsmhq swlprvvaaa
      361 fytedptgsc allqrtqpqa vtaastcipq mplqkllfsa tltqnpeklq rlglyqprlf
      421 strlghqspr dtvevdenlg kytfpvglth hyvpcrlssk plivfhlvlg mnfsralcft
      481 nsrenshrlf llaqafggvs vaefssrygp gqrkkilkqf eqgkiqllis tdatargidv
      541 qgvelvinyd apqylrtyvh rvgrtaragk tgqaftlllk vqerkflqmv seagvpelac
      601 hevprkllqp lvaryetals qlektvkeeq klkaa
//
