LOCUS       NM_001013198            2521 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DExD-box helicase 50 (Ddx50), mRNA.
ACCESSION   NM_001013198 XM_342142
VERSION     NM_001013198.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2521)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2521)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2521)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Sep 11, 2008 this sequence version replaced NM_001013198.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.44046.1,
                                           SRR26643297.53411.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-191               JAXUCZ010000020.1  31133462-31133652   c
            192-479             JAXUCZ010000020.1  31129349-31129636   c
            480-555             JAXUCZ010000020.1  31125634-31125709   c
            556-734             JAXUCZ010000020.1  31125115-31125293   c
            735-852             JAXUCZ010000020.1  31123089-31123206   c
            853-1038            JAXUCZ010000020.1  31122792-31122977   c
            1039-1184           JAXUCZ010000020.1  31122198-31122343   c
            1185-1334           JAXUCZ010000020.1  31117887-31118036   c
            1335-1496           JAXUCZ010000020.1  31112106-31112267   c
            1497-1616           JAXUCZ010000020.1  31110760-31110879   c
            1617-1690           JAXUCZ010000020.1  31109949-31110022   c
            1691-1850           JAXUCZ010000020.1  31109567-31109726   c
            1851-1985           JAXUCZ010000020.1  31107202-31107336   c
            1986-2030           JAXUCZ010000020.1  31106108-31106152   c
            2031-2521           JAXUCZ010000020.1  31104354-31104844   c
FEATURES             Location/Qualifiers
     source          1..2521
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..2521
                     /gene="Ddx50"
                     /note="DExD-box helicase 50"
                     /db_xref="GeneID:361848"
                     /db_xref="RGD:1310934"
     exon            1..191
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     CDS             105..2309
                     /gene="Ddx50"
                     /EC_number="3.6.4.13"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; DEAD-box
                     helicase 50"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DDX50"
                     /protein_id="NP_001013216.2"
                     /db_xref="GeneID:361848"
                     /db_xref="RGD:1310934"
                     /translation="MPGKLLWGDIMELEAPLEESESQRKERQKNDRRKSRHHSESEER
                     TETRENGVTDDLDAPKPKKAKTREKLNGDTKEGLRFSDEFSPSHKSRRKDLPNGDVDE
                     YEKRSKRVSSSENSHKSSDKADETLTREQKEGAFSNFSISEETIKLLKGRGVTYLFPI
                     QVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIERLQRNQETIKKSRSPKVLVLAPTR
                     ELANQVAKDFKDITRKLNVACFYGGTSYQSQINQIRNGIDILVGTPGRIKDHLQSGRL
                     DLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKSDSEDNPQTLLFSATCPQWVYKVA
                     KKYMKSRYEQVDLVGKMTQKAATTVEHLAIQCHWSQRPAVIGDVLQVYSGSEGRAIIF
                     CETKKNVTEMAMNPHIKQNAQCLHGDIAQSQREITLKGFREGSFKVLVATNVAARGLD
                     IPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICVCFYQPRERGQLRYVEQKAGITF
                     KRVGVPSTMDLVKSKSMDAIRSLASVSYAAVDFFRPSAQRLIEEKGAVDALAAALAHI
                     SGASSFEPRSLITSDKGFVTMTLESPEEIQDVSCAWKELNRKLSSNAVSQVTRMCLLK
                     GNMGVCFDVPTSESERLQAEWHDSDWILSVPAKLPEIEEYYDGNTSSNPRQRSGWSGG
                     RSGRSGRSGGRSGGRSGRQSRQGSRSGSRQDGRRRSGNRNRSRSGGHKRSFD"
     exon            192..479
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            480..555
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            556..734
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            735..852
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            853..1038
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1039..1184
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1334
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1335..1496
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1497..1616
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1690
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..1850
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1851..1985
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            1986..2030
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
     exon            2031..2521
                     /gene="Ddx50"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acggtcctgg ccggcggccg cccagccccc gcttcctttc acgctatcgg tggccgtagg
       61 tggtcgtggc caccgcaccc ggcgggaggt ggcggcggcc agtaatgccc gggaaactcc
      121 tctggggaga catcatggag ctcgaggcac ccttggaaga gtccgagagc cagaggaagg
      181 agcggcaaaa gaatgataga aggaagtcaa ggcaccattc tgaatcagag gagagaacag
      241 aaacaagaga aaatggtgtt acagatgacc tggatgctcc caagcccaaa aaagctaaaa
      301 cgagagagaa gctaaatgga gacaccaaag aaggacttag attttcagat gaattttccc
      361 catctcataa gtcaagaaga aaagacctgc caaatggaga tgtggatgag tatgagaaaa
      421 ggtctaaacg agtgtcatcc tcagaaaact ctcacaagtc aagtgataaa gcagatgaga
      481 ctctaacacg tgagcaaaag gaaggagcct tctctaattt ctccatttct gaggagacca
      541 taaagcttct gaaaggtcga ggggtaacat atctctttcc tattcaagtt aaaacctttg
      601 gccctgtcta tgaaggaaaa gacttaattg ctcaagcccg gacaggaaca ggaaagacat
      661 tctcttttgc catacccttg attgaaaggc tccaaagaaa tcaagaaaca attaaaaaaa
      721 gccgctcacc aaaggtactc gttttggctc caacaaggga attggcaaat caagtagcca
      781 aagatttcaa agatataact agaaaactca atgtggcgtg tttttatggt ggaacatcat
      841 atcaaagcca gattaatcaa attcggaatg gtattgacat ccttgttggg accccaggac
      901 gtatcaaaga ccatctgcaa agcggccgtt tggatctttc aaagcttcgc catgttgtac
      961 ttgatgaagt agatcaaatg ttagatttag gttttgctga acaagttgaa gatattattc
     1021 atgaatccta taaatctgat tcagaagaca atcctcagac cttacttttt tctgcaactt
     1081 gcccacagtg ggtatacaaa gttgcaaaaa aatacatgaa atccagatat gaacaggttg
     1141 accttgttgg aaaaatgact caaaaagctg caaccactgt ggaacatttg gctatccagt
     1201 gccactggtc ccagagacca gcagttattg gagatgtcct tcaggtctac agtggatctg
     1261 aagggagagc tattatcttc tgtgagacta agaagaatgt tactgaaatg gccatgaatc
     1321 cacacataaa gcagaacgca cagtgtttgc atggagatat tgcacagtca caaagagaaa
     1381 ttaccttgaa aggcttcaga gaaggtagtt ttaaagtttt ggtggcaacc aatgtggctg
     1441 ctcgtggctt ggacattcct gaagttgatc ttgtgattca gagttctcct ccacaggatg
     1501 ttgaatccta tatccatcgc tctggacgca caggtagagc tggccggaca ggaatttgtg
     1561 tatgttttta tcaaccaagg gaaagaggtc aactgagata tgtggaacag aaagcaggaa
     1621 ttacttttaa acgtgtaggt gttccttcta caatggattt agttaaatct aaaagcatgg
     1681 atgccatcag gtctctggct tctgtttctt atgctgctgt tgattttttc cgaccatcag
     1741 ctcaaagact gatagaagag aagggggcag tggatgcatt ggctgcagcc ttagctcaca
     1801 tttctggtgc atcaagcttt gaaccccgat ctttgatcac ctctgataag gggtttgtga
     1861 ccatgactct ggaaagccca gaagaaatac aggatgtcag ctgtgcttgg aaggaactta
     1921 atagaaagct cagtagtaat gctgtgtctc aagtaaccag aatgtgcctc ctgaaaggaa
     1981 atatgggtgt ttgctttgat gttcctacaa gtgagtcaga aagattacag gcagagtggc
     2041 atgactcaga ctggatactc tcagtgccag ccaagttacc tgaaattgaa gaatattatg
     2101 atggaaacac atcttctaat cccagacaga ggagcggctg gtctggcggc aggtcaggcc
     2161 gttcaggccg atctggtggt cgatctggtg gccgatcagg tagacagagt cgacagggga
     2221 gtcgttcagg aagtcggcaa gacggtagaa gacgaagtgg gaacagaaat cgatcaagaa
     2281 gtgggggcca taaacggagt tttgactgag tgtttgatag ttaatcttcc agtgtgagct
     2341 tgcctatttc tgtctaatca tgtatattat tcaccaaaaa ttagatcatc atagttgagg
     2401 tatttgtctg taatttgcaa agaagttggt cgtatttttt taaaaagtat ttcacaagaa
     2461 tggttctaaa caaatctact tatctggcta tacctttgaa ttaaaaagaa agccctttta
     2521 t
//
