LOCUS       NM_001107059            4068 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus DEAD-box helicase 42 (Ddx42), mRNA.
ACCESSION   NM_001107059 XM_001081592 XM_221037
VERSION     NM_001107059.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 4068)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 4068)
  AUTHORS   Uhlmann-Schiffler,H., Kiermayer,S. and Stahl,H.
  TITLE     The DEAD box protein Ddx42p modulates the function of ASPP2, a
            stimulator of apoptosis
  JOURNAL   Oncogene 28 (20), 2065-2073 (2009)
   PUBMED   19377511
REFERENCE   4  (bases 1 to 4068)
  AUTHORS   Chen,Y.I., Moore,R.E., Ge,H.Y., Young,M.K., Lee,T.D. and
            Stevens,S.W.
  TITLE     Proteomic analysis of in vivo-assembled pre-mRNA splicing complexes
            expands the catalog of participating factors
  JOURNAL   Nucleic Acids Res 35 (12), 3928-3944 (2007)
   PUBMED   17537823
REFERENCE   5  (bases 1 to 4068)
  AUTHORS   Qian,J., Chen,Z., Wang,W., Cen,J. and Xue,Y.
  TITLE     Gene expression profiling of the bone marrow mononuclear cells from
            patients with myelodysplastic syndrome
  JOURNAL   Oncol Rep 14 (5), 1189-1197 (2005)
   PUBMED   16211284
REFERENCE   6  (bases 1 to 4068)
  AUTHORS   Lecker,S.H., Jagoe,R.T., Gilbert,A., Gomes,M., Baracos,V.,
            Bailey,J., Price,S.R., Mitch,W.E. and Goldberg,A.L.
  TITLE     Multiple types of skeletal muscle atrophy involve a common program
            of changes in gene expression
  JOURNAL   FASEB J 18 (1), 39-51 (2004)
   PUBMED   14718385
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_221037.3, XM_001081592.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132263 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..4068
                     /gene="Ddx42"
                     /note="DEAD-box helicase 42"
                     /db_xref="GeneID:303607"
                     /db_xref="RGD:1304909"
     exon            1..236
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            237..468
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..3037
                     /gene="Ddx42"
                     /EC_number="3.6.1.-"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 42; DEAD
                     (Asp-Glu-Ala-Asp) box helicase 42"
                     /codon_start=1
                     /product="ATP-dependent RNA helicase DDX42"
                     /protein_id="NP_001100529.1"
                     /db_xref="GeneID:303607"
                     /db_xref="RGD:1304909"
                     /translation="MNWNKGGPGTKRGFGFGGFAISAGKKEEAKLPQQSHSAFGAASS
                     SSGFGKSAPPQLPSFYKIGSKRANFDEENAYFEDEEEDSSNVDLPYIPAENSPTRQQF
                     RSKPADSDSDDDPLEAFMAEVEDQAARDMKRLEEKDKERKNVKGIRDDIEEEDDQEAY
                     FRYMAENPTAGVVQEEEEDNLEYDSDGNPIAPSKKIIDPLPPIDHSEIDYPPFEKNFY
                     NEHEEITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQP
                     TPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCP
                     TRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVK
                     KKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLAR
                     DILIDPIRVVQGDIGEANEDVTQIVEILHSGPSKWNWLTRRLVEFTSSGSVLLFVTKK
                     ANAEELANNLKQEGHNLGLLHGDMDQSERNKVILDFKKKDIPVLVATDVAARGLDIPS
                     IKTVINYDVARDIDTHTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHV
                     SKELLDLAMQNAWFRKSRFKGGKGKKLNIGGGGLGYRERPGLGSENSDRGSNNNVMSN
                     YEAYKPSTGAMGDRLTAMKAAFQSQYKSHFVAASLSNQKAGTSTAGASGWTSAGSLNS
                     VPTNSAQQGHNSPDNPITSSTKNIPGFNNSGNISSAPVTYPSIGAQGVNNTASGSNSR
                     EGIGGGNGKRERYTENRGGGRHSHGDSGNRHGDGGRHGDGYRYPESSSRHTDGHRHGE
                     TRHGGSASRHGESRGANDGRNGESRKEGFNRENRMDPKVDSSRMDKVDSKTDKTPDGF
                     AVPEPPKRKKSRWDS"
     exon            469..619
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            620..681
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            682..718
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            719..868
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            869..973
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1093
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..1270
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1399
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1400..1499
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1500..1547
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1548..1645
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1646..1922
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            1923..2149
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            2150..2260
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            2261..2362
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
     exon            2363..4068
                     /gene="Ddx42"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcagcgcgca tgtcagatgc actcccccac cccaccccca gtcagcaacg ggccgtgagg
       61 cggcggcgaa gggggcggag gaagagtgcg gctggacgcg gtcccgcacc gcgcgtacgc
      121 agggccgcgg gggttctttc gcgccgactg tagtagcaac tgcgtctgca gccgcagcag
      181 caggtttgtg taaagggctc tccagacgca gcgccgctag ccccggggca cgagagtcat
      241 cgtcatcatg aattggaata aaggtggacc tggaaccaag cgggggtttg gctttggagg
      301 ttttgccatc agtgctggga agaaggagga agccaagctg ccgcagcagt cgcacagtgc
      361 cttcggggcg gccagctctt cttctggatt tggaaagtct gctccaccac agcttccttc
      421 tttctacaaa attggatcta aacgggccaa ctttgatgaa gaaaatgctt atttcgagga
      481 tgaagaagaa gactccagca atgtagactt accttacatt cctgctgaaa actcgcctac
      541 ccgccagcag ttccgatcca agccagcaga ctctgacagt gacgacgacc ccttagaggc
      601 attcatggct gaagtagagg atcaggcggc tagagacatg aagagacttg aggaaaagga
      661 caaggaaaga aaaaacgtaa agggtattcg agatgacatt gaagaggaag atgaccaaga
      721 agcttatttt cgatacatgg cagaaaaccc aactgctggg gtagttcagg aggaagagga
      781 agacaatctg gagtatgata gtgatggaaa tccaattgca ccttctaaaa agattatcga
      841 tccccttcct cccattgatc attcggagat tgactatcca ccatttgaaa aaaattttta
      901 caatgaacat gaggagataa ccaacctcac tccacagcag ctaatagacc tgcggcataa
      961 actcaacctt cgggtctctg gtgctgcacc tcctagacca ggaagtagtt ttgctcattt
     1021 tgggtttgat gaacaactta tgcatcagat taggaaatct gagtacacac agccaactcc
     1081 aatacagtgt cagggtgtgc ccgtagcact aagtggtaga gacatgatcg gtattgctaa
     1141 aacaggcagt gggaaaaccg cagcctttat ttggcccatg ttgattcaca taatggatca
     1201 gaaggagttg gaaccaggtg atggaccaat tgcagtgatt gtgtgtccta ctagggagct
     1261 ttgtcaacag atccacgccg agtgcaagcg ttttgggaaa gcatataatc ttcgatcagt
     1321 ggcagtatat ggaggaggga gcatgtggga gcaggccaag gcccttcagg aaggggcaga
     1381 gattgttgtg tgtaccccgg gtcggctgat tgatcatgtg aagaaaaaag ctaccaatct
     1441 tcaaagagtc tcttaccttg tgtttgatga agctgatcga atgttcgaca tggggtttga
     1501 gtatcaggtt cggtccatag caagtcatgt ccgtcctgac agacaaactc tcttattcag
     1561 tgcaactttt cggaaaaaga ttgaaaaatt ggccagagac atcttgattg atcctatccg
     1621 agtggtacaa ggagacatcg gagaggcaaa tgaagacgta acacagattg tggagattct
     1681 ccattctgga cctagtaaat ggaactggct cactcggcgt ctggtagagt ttacttcttc
     1741 cgggagtgtc ctcttgtttg ttaccaagaa agccaacgct gaagaactgg ccaataacct
     1801 taagcaggag ggtcataatc ttggtctgct ccatggggac atggatcaga gtgaaagaaa
     1861 caaggtcatt ttagatttta agaaaaaaga catccccgtc ctggtggcca ctgacgttgc
     1921 agcccgtggt ctggatattc cttcaattaa gacagtcatt aactatgatg ttgcacgaga
     1981 cattgatacc catactcata ggattggccg aacaggaaga gctggtgaga agggtgtagc
     2041 ctatacctta ctgaccccaa aggacagcaa ttttgctggt gaccttgtac ggaacctgga
     2101 aggagccaac caacatgttt ctaaggaact cttagatctc gcaatgcaga acgcctggtt
     2161 tcggaagtca cgcttcaaag gagggaaagg caaaaagctg aacatcggtg gaggaggctt
     2221 gggctataga gagcggcctg ggctgggctc tgagaattcg gaccgaggaa gtaacaacaa
     2281 tgtaatgagc aattatgaag cctacaagcc ctccacagga gccatgggag ataggctgac
     2341 agcaatgaaa gcagctttcc agtcccagta taagagtcac tttgttgcag ccagtttaag
     2401 taatcagaag gccggaacct ctactgctgg ggcaagtgga tggactagtg caggaagctt
     2461 aaattctgtt ccaactaatt cagcacagca gggccataat agtcctgaca atcccatcac
     2521 cagttctacc aagaacatcc caggcttcaa caattctggg aatatcagta gtgccccagt
     2581 gacctaccct tctattggag cccaaggagt caacaacaca gcttcaggga gtaacagccg
     2641 tgaagggatt gggggtggca atgggaaaag agagagatat actgagaacc ggggtggtgg
     2701 ccgtcatagc catggagaca gtggcaatcg acatggagat ggtggccgcc atggagatgg
     2761 ataccgttac ccagaaagca gtagccgtca tacggatggc caccgacatg gagagaccag
     2821 gcacggagga agtgcaagca gacatggaga aagccggggt gcaaatgatg gcaggaatgg
     2881 agaaagcagg aaagaaggct ttaatcgtga aaacaggatg gaccccaagg tggacagcag
     2941 caggatggac aaagtggaca gcaagacaga taagacacct gatggctttg ctgttccaga
     3001 gccacccaaa cgcaagaaaa gccgatggga tagttagagg gtatgtgaaa atcagcgtgg
     3061 tcagttgtct ttcattttat ttttagaaag attttggtaa tgaggtgtct cagggctggg
     3121 ttggggtcca agatatacag accccctgcc cttggtggag aactggagcg tggagatatt
     3181 ataccttcat ctggtgttca ttcagatgtt ttcatgggaa cctgagttgg ccctagaaag
     3241 cagagggctg ggaagctttt gtttgctctg ggtgagttta aggaggggta agtaggaaat
     3301 gcttagggag aaaggaaggg ccttttaggg cacaaaaact cactctaggt ttataatagc
     3361 ttatattttt tactaaaatg tcaccttata aacatctata attggatttt ttttcttagc
     3421 tgtggccagg cagtcccata ttttggagtt ggcgtctaca aacccaactt ttgacctgtt
     3481 atggctgctt gggagcagtt tggtgctttc agatgtttgc agggaagata cctgataact
     3541 cagcttcccc agactttgtt tccagccctg agacatgtag gagacatgta gggaaagaca
     3601 gccttccaga cagacacagg ctttgaaatc ctaagccatt aggactgaag gaatgatcat
     3661 cttggaggga ttccaggatt atccaggcct ggagtactgc taaatttacc gtttcaaacc
     3721 aaccccaaca gtagctttca aagtgtctat ttcattgttt tgtttttttt tttaacttgc
     3781 cctaatagta gaaaaagtct tttgctgaaa tgattctgat ttttgttcta tcttgtttat
     3841 aaaaggaaaa gaaatataca aactttgaat tttgtgattt ttgtgaggtt tctttaagat
     3901 gtgcattccc tctctgcttg ctcgatagta aatgtcttac tactgggacc tgagggctgt
     3961 cgtttctacc atacagttag ttgctacata ttaaattatg gcttggaaca gtacagccca
     4021 tgatgtgaaa tgtggggaaa tgcttgctta ttaaactatc agaaaagt
//
