LOCUS       NM_133300               1711 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus DExD-box helicase 39B (Ddx39b), mRNA.
ACCESSION   NM_133300 XM_346595 XM_347362
VERSION     NM_133300.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Ishizuka,A., Hasegawa,Y., Ishida,K., Yanaka,K. and Nakagawa,S.
  TITLE     Formation of nuclear bodies by the lncRNA Gomafu-associating
            proteins Celf3 and SF1
  JOURNAL   Genes Cells 19 (9), 704-721 (2014)
   PUBMED   25145264
REFERENCE   2  (bases 1 to 1711)
  AUTHORS   Chang,T.H., Tung,L., Yeh,F.L., Chen,J.H. and Chang,S.L.
  TITLE     Functions of the DExD/H-box proteins in nuclear pre-mRNA splicing
  JOURNAL   Biochim Biophys Acta 1829 (8), 764-774 (2013)
   PUBMED   23454554
  REMARK    Review article
REFERENCE   3  (bases 1 to 1711)
  AUTHORS   Sahni,A., Wang,N. and Alexis,J.
  TITLE     UAP56 is an important mediator of angiotensin II/platelet derived
            growth factor induced vascular smooth muscle cell DNA synthesis and
            proliferation
  JOURNAL   Biochem Biophys Res Commun 431 (3), 636-640 (2013)
   PUBMED   23246467
  REMARK    GeneRIF: These findings suggest that UAP56 is a regulator of VSMC
            proliferation and identify UAP56 as a target for preventing
            vascular proliferative disease.
REFERENCE   4  (bases 1 to 1711)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   5  (bases 1 to 1711)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   6  (bases 1 to 1711)
  AUTHORS   Lambracht-Washington,D. and Fischer Lindahl,K.
  TITLE     Does the rat have an H2-D orthologue next to Bat1?
  JOURNAL   Immunogenetics 53 (12), 1039-1046 (2002)
   PUBMED   11904681
  REMARK    GeneRIF: To determine whether the rat possesses an H2-D orthologue,
            we sequenced a cosmid clone that contains rat Bat1 and an adjacent
            class I gene, RT1.46 (l).
REFERENCE   7  (bases 1 to 1711)
  AUTHORS   Cheong,K.Y., Allcock,R.J., Eerligh,P., Witt,C.S.,
            Christiansen,F.T., McCann,V. and Price,P.
  TITLE     Localization of central MHC genes influencing type I diabetes
  JOURNAL   Hum Immunol 62 (12), 1363-1370 (2001)
   PUBMED   11756005
REFERENCE   8  (bases 1 to 1711)
  AUTHORS   Gohshi,T., Shimada,M., Kawahire,S., Imai,N., Ichimura,T., Omata,S.
            and Horigome,T.
  TITLE     Molecular cloning of mouse p47, a second group mammalian RuvB DNA
            helicase-like protein: homology with those from human and
            Saccharomyces cerevisiae
  JOURNAL   J Biochem 125 (5), 939-946 (1999)
   PUBMED   10220587
REFERENCE   9  (bases 1 to 1711)
  AUTHORS   Helou,K., Yan,Q., Yuan,X.J., Kunz,H.W., Levan,G. and Gill,T.J. 3rd.
  TITLE     Cytogenetic localization of the growth and reproduction complex
            (Grc) in the rat and in the mouse and its position in relation to
            RT1.EC and other loci in the rat MHC
  JOURNAL   Hereditas 130 (2), 105-109 (1999)
   PUBMED   10479997
REFERENCE   10 (bases 1 to 1711)
  AUTHORS   Nair,S., Dey,R., Sanford,J.P. and Doyle,D.
  TITLE     Molecular cloning and analysis of an eIF-4A-related rat liver
            nuclear protein
  JOURNAL   J Biol Chem 267 (18), 12928-12935 (1992)
   PUBMED   1618789
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DY309526.1 and BC080243.1.
            
            On Oct 2, 2009 this sequence version replaced NM_133300.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ212901.1, BC080243.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN16676807
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-400               DY309526.1         1-400
            401-1711            BC080243.1         350-1660
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1711
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /note="DExD-box helicase 39B"
                     /db_xref="GeneID:114612"
                     /db_xref="RGD:70923"
     exon            1..67
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            68..405
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     CDS             195..1481
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /EC_number="3.6.4.13"
                     /note="spliceosome RNA helicase Bat1; DEAD box protein
                     UAP56; ATP-dependent RNA helicase p47; 56 kDa
                     U2AF65-associated protein; DEAD-box helicase 39B; Nuclear
                     RNA helicase; D20H6S81e; D17H6S81E-1; HLA-B associated
                     transcript 1; HLA-B-associated transcript 1A; DEAD
                     (Asp-Glu-Ala-Asp) box polypeptide 39B"
                     /codon_start=1
                     /product="spliceosome RNA helicase Ddx39b"
                     /protein_id="NP_579834.2"
                     /db_xref="GeneID:114612"
                     /db_xref="RGD:70923"
                     /translation="MAENDVDNELLDYEDDEVETAAGADGTEAPAKKDVKGSYVSIHS
                     SGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLA
                     TLQQLEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEV
                     LKKNCPHIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMT
                     PHEKQVMMFSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNEKNR
                     KLFDLLDVLEFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFK
                     DFQRRILVATNLFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVS
                     DENDAKILNDVQDRFEVNISELPDEIDISSYIEQTR"
     exon            406..533
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            534..626
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            627..810
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            811..929
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            930..1061
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            1062..1171
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1316
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            1317..1464
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1690
                     /gene="Ddx39b"
                     /gene_synonym="Bat1; Bat1a; p47"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggaagtga aggcagcttc ccgcctccgt ccctgttgct gccgccatac acgctcgcag
       61 tgcttagctc ttctgtcgga aactggtgtc ttttcccttg ctgttctcca acccctctct
      121 ttccccttgc ttcctctcac ctgctctggg acacctaact cagagacctc ccttctcccc
      181 ccgccggccg gattatggca gagaacgatg tggacaatga gctcttggac tatgaagacg
      241 atgaggtgga gacggccgct ggggcagatg ggaccgaagc tcccgccaag aaagacgtca
      301 agggctccta tgtctccatc cacagctccg gctttcgaga tttcctactt aagccagagt
      361 tgctccgggc cattgttgac tgtggctttg agcatccatc agaggtccag catgaatgca
      421 tcccccaggc cattctgggg atggatgtcc tgtgccaggc caagtcaggc atgggaaaaa
      481 cagcagtgtt tgtcctggcc acactgcagc agctggagcc agttactggg caggtgtcag
      541 tgctggtgat gtgtcacacc agggagctgg ctttccagat cagcaaggaa tatgagcgct
      601 tctcaaagta catgccgaat gtcaaggtgg cagtgttttt tggcggactg tctatcaaga
      661 aggatgaaga ggtgctgaag aagaactgcc cacacattgt tgtggggact cctggccgaa
      721 ttctagccct ggcccgaaat aagagcctga acctcaaaca cattaaacac tttatcttgg
      781 acgaatgtga caagatgctt gaacagctcg acatgcgtcg ggatgtccag gaaatttttc
      841 gcatgacccc ccatgagaag caggtcatga tgttcagtgc taccttgagc aaagagatcc
      901 gcccagtgtg ccgcaagttc atgcaagatc ctatggagat cttcgtggat gacgagacca
      961 agttgacgct gcacgggttg cagcaatact acgtgaaact gaaggacaac gagaagaacc
     1021 ggaagctctt tgaccttctc gatgtcctcg agttcaacca ggttgtgatc tttgtgaagt
     1081 ccgtgcagcg ctgcatcgcc ttggcccagc ttctagtgga gcagaacttc ccagccattg
     1141 ctatccaccg cgggatgccc caggaggaga ggctctctcg gtatcagcag ttcaaggatt
     1201 ttcagcggag gatacttgtg gctaccaacc tgtttggccg tggcatggac attgagcgcg
     1261 tgaacatcgc tttcaactat gacatgccag aggactccga cacctacctg cacagggtgg
     1321 ccagagcggg ccggtttggc accaagggct tggccatcac atttgtgtca gacgagaacg
     1381 atgccaagat cctgaatgac gtgcaggacc gtttcgaggt caacatcagt gagctgcccg
     1441 atgagatcga catttcctcc tacattgaac agacacggta gaggaatcac ctattctgga
     1501 ccgtggcagt ctgttgtaga agaggacgaa ggggtcaggg aggaaacact actgccccac
     1561 ccctgacacc tcagcccacc ctctccatgc ctctctgcgt caccaccact cctaaaccta
     1621 gtcctgattt atcagagttg tttgtttgtt tgtttgtttt tgttttttaa caaaactaag
     1681 aatgaaacaa aaaaaaaaaa aaaaaaaaaa a
//
