LOCUS       NM_001135801            2608 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus DEAD-box helicase 27 (Ddx27), mRNA.
ACCESSION   NM_001135801 XM_001075340 XM_342582
VERSION     NM_001135801.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2608)
  AUTHORS   Kellner M, Rohrmoser M, Forne I, Voss K, Burger K, Muhl B,
            Gruber-Eber A, Kremmer E, Imhof A and Eick D.
  TITLE     DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S
            RNA and stably associates with the PeBoW-complex
  JOURNAL   Exp Cell Res 334 (1), 146-159 (2015)
   PUBMED   25825154
REFERENCE   2  (bases 1 to 2608)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2608)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2608)
  AUTHORS   Ohta S, Bukowski-Wills JC, Sanchez-Pulido L, Alves Fde L, Wood L,
            Chen ZA, Platani M, Fischer L, Hudson DF, Ponting CP, Fukagawa T,
            Earnshaw WC and Rappsilber J.
  TITLE     The protein composition of mitotic chromosomes determined using
            multiclassifier combinatorial proteomics
  JOURNAL   Cell 142 (5), 810-821 (2010)
   PUBMED   20813266
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC160885.1.
            
            On or before Oct 16, 2008 this sequence version replaced
            XM_342582.3, XM_001075340.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC160885.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2608
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q42"
     gene            1..2608
                     /gene="Ddx27"
                     /note="DEAD-box helicase 27"
                     /db_xref="GeneID:362274"
                     /db_xref="RGD:1305634"
     exon            1..107
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     CDS             15..2300
                     /gene="Ddx27"
                     /EC_number="3.6.4.13"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 27"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DDX27"
                     /protein_id="NP_001129273.1"
                     /db_xref="GeneID:362274"
                     /db_xref="RGD:1305634"
                     /translation="MLAELGFIGTIGENDEVPVEPESDSGDEEEEGPIVLGLKQKALQ
                     KNRSADFNPDFVFTEKQGTYDGSWALADVMSQLKKKRAATTLDEKIEKVRKKRKAEDK
                     EAKSGKAEEKEGQEGSDLKGQENLGENEAGSKDEESETDYSSEDEEILTKADTLKVKE
                     KKKKKKGQESGGFFEDASEYDKSLTFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVG
                     LLGKDICACAATGTGKTAAFALPVLERLIYKPRQAAVTRVLVLVPTRELGIQVHSVTK
                     QLAQFCSITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVL
                     ILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVN
                     SNTDVAPFLRQEFIRIRPNREGDREAIVAALLMRTFTDHVMLFTQTKKQAHRMHILLG
                     LLGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPN
                     TVKHYVHRVGRTARAGRAGRSVSLVGEEERKMLKEIVKAAKAPVKARILPQDVILKFR
                     DKIEKMEKDVYAVLQLEAEEREVQQSEAQIDTAQRLLSKGKQTADQEPERSWFQTKEE
                     RKKEKIAKALQEFDLALRGKKKRKKFMKDVKKKGEMTAEERSQFEILKAQMFAERLAK
                     RNRRTKRARAMPEEEPAAGPAKKQKQHKKSVFDEELTNTSKKALKQYRAGPSFEERKQ
                     LGLPRQRRGNFKSKSRYKRKK"
     exon            108..254
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            255..314
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            315..474
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            475..518
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            519..605
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            606..711
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            712..885
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1036
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..1136
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1278
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1279..1432
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1514
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1515..1692
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1693..1799
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1800..1902
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..1997
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            1998..2121
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            2122..2209
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2281
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
     exon            2282..2585
                     /gene="Ddx27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgcatctt caacatgctg gcggagctcg gtttcatcgg gaccatcggc gaaaatgacg
       61 aggtgccggt tgaacccgag tcggattccg gagacgagga ggaggaggga cccattgtgc
      121 tgggcctcaa gcagaaagcc ctgcagaaga accgcagtgc tgacttcaac cctgactttg
      181 ttttcactga gaagcagggc acgtatgatg gtagctgggc cctggctgac gtcatgagcc
      241 agctcaagaa gaagagggca gccactaccc tggatgagaa gattgagaaa gtacggaaga
      301 aaaggaaagc agaggataag gaagccaagt ctgggaaggc agaggagaaa gaaggccagg
      361 agggctctga cctgaagggg caggagaatc taggagagaa tgaggcaggc tccaaggacg
      421 aagagtctga gactgactac tcctctgagg atgaggagat cctcaccaaa gcagacacac
      481 tcaaagtgaa ggagaagaag aagaagaaga agggccagga atcaggagga ttctttgaag
      541 atgcatctga atatgacaaa agcctgacct tccaggacat gaacctctcc cggcccctcc
      601 tgaaggccat tacagccatg ggcttcaagc agcccactcc aattcagaag gcatgcattc
      661 ctgtgggtct gctggggaaa gacatctgcg cctgcgcagc tactgggaca ggcaaaacgg
      721 cagcctttgc actgccagtc ttagagcgtc tgatctacaa gccccgtcag gctgcggtca
      781 ctcgagtgct ggtgctggtc cccaccagag agctgggcat ccaagtgcac tctgtcacca
      841 agcagctggc ccagttctgc agcatcacta cctgcctggc tgtggggggc ctggatgtga
      901 agtctcagga agccgctctt cgggcagcac cagacatcct cattgccact cctggccggc
      961 tcatcgacca cctccacaac tgcccttcct tccacctgag cagcattgaa gtgctcatct
     1021 tggacgaggc tgacaggatg ctggatgagt attttgagga gcagatgaag gagattatcc
     1081 gaatgtgttc ccaccaccgc cagaccatgc tcttctcggc caccatgaca gatgaggtga
     1141 aagatctggc ttcggtctcc ttaaagaatc ctgtgcggat atttgtgaac agcaacacag
     1201 atgtagctcc cttcctacgg caagagttca tccggatccg gcctaacagg gaaggggacc
     1261 gggaagccat tgtggcagct ctactgatga gaacctttac tgaccacgtg atgctgttca
     1321 cccagaccaa gaagcaggcc catcgcatgc acatcctcct agggctgctg gggctgcagg
     1381 tgggcgagct ccatggtaac ttgtcacaga cgcagcggct ggaagctctc cggcgcttta
     1441 aggatgaaca gattgacatc ctggtagcca cagatgtggc agcccgtggg cttgacattg
     1501 aaggagtgaa aacagtgatc aacttcacca tgcccaacac tgtcaaacac tatgtgcacc
     1561 gggtggggcg aactgcacgt gctggcaggg ctgggcgctc tgtctctctg gtgggagaag
     1621 aggagcggaa gatgctgaag gagatcgtaa aggctgccaa ggctccagtg aaggctcgga
     1681 tccttcccca ggatgttatc ctcaaattcc gggacaagat tgagaaaatg gagaaagatg
     1741 tgtatgcagt gctgcagctg gaggcggagg agagagaggt gcagcagtca gaagcccaga
     1801 tcgacacagc acagcgactc ttatccaaag ggaaacagac agcagaccag gaacctgaga
     1861 ggagctggtt tcagaccaaa gaagagagga aaaaggagaa gattgccaag gctctgcagg
     1921 agtttgactt ggccttaaga ggaaagaaga aaaggaagaa gtttatgaag gacgtcaaga
     1981 aaaaggggga gatgacggcg gaggagaggt cccagtttga aatcctcaag gcacagatgt
     2041 ttgcagagcg gctggccaag aggaaccgca gaaccaagcg agcacgggca atgcctgagg
     2101 aagagcctgc agcaggccct gccaagaagc agaagcagca caagaagtct gtgtttgatg
     2161 aagaactcac caacacaagc aagaaggccc tgaaacagta ccgggctggc ccttcctttg
     2221 aagagaggaa acagttaggt ctgccccgcc agaggagagg gaacttcaag tctaagtcca
     2281 ggtacaagag aaagaagtag tatgagtggt gtgaagaagt tggtgggaca attttatatc
     2341 ccttccctgt gggaagtcat cttgtcttgg tctgaatttt tccatttatg aaaccccaaa
     2401 cccgaggctg gagagatggc tcactggtta agagcactga ctgttcttcc agaggaccgg
     2461 agttcaaatc ccagcaacca catggtggct cacaaccatc tgtaatggga tctgatgccc
     2521 tcttctgatg tgtctgaaga cagctaccat gtacatacgt acataaataa aatctttaaa
     2581 aacaaaaaaa aaaaaaaaaa aaaaaaaa
//
