LOCUS       NM_001191711            2752 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus DEAD-box helicase 20 (Ddx20), mRNA.
ACCESSION   NM_001191711 XM_227558
VERSION     NM_001191711.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2752)
  AUTHORS   Yong,J., Kasim,M., Bachorik,J.L., Wan,L. and Dreyfuss,G.
  TITLE     Gemin5 delivers snRNA precursors to the SMN complex for snRNP
            biogenesis
  JOURNAL   Mol Cell 38 (4), 551-562 (2010)
   PUBMED   20513430
REFERENCE   2  (bases 1 to 2752)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2752)
  AUTHORS   Chari,A., Golas,M.M., Klingenhager,M., Neuenkirchen,N., Sander,B.,
            Englbrecht,C., Sickmann,A., Stark,H. and Fischer,U.
  TITLE     An assembly chaperone collaborates with the SMN complex to generate
            spliceosomal SnRNPs
  JOURNAL   Cell 135 (3), 497-509 (2008)
   PUBMED   18984161
REFERENCE   4  (bases 1 to 2752)
  AUTHORS   Mouillet,J.F., Yan,X., Ou,Q., Jin,L., Muglia,L.J., Crawford,P.A.
            and Sadovsky,Y.
  TITLE     DEAD-box protein-103 (DP103, Ddx20) is essential for early
            embryonic development and modulates ovarian morphology and function
  JOURNAL   Endocrinology 149 (5), 2168-2175 (2008)
   PUBMED   18258677
REFERENCE   5  (bases 1 to 2752)
  AUTHORS   Lee,K., Pisarska,M.D., Ko,J.J., Kang,Y., Yoon,S., Ryou,S.M.,
            Cha,K.Y. and Bae,J.
  TITLE     Transcriptional factor FOXL2 interacts with DP103 and induces
            apoptosis
  JOURNAL   Biochem Biophys Res Commun 336 (3), 876-881 (2005)
   PUBMED   16153597
REFERENCE   6  (bases 1 to 2752)
  AUTHORS   Klappacher,G.W., Lunyak,V.V., Sykes,D.B., Sawka-Verhelle,D.,
            Sage,J., Brard,G., Ngo,S.D., Gangadharan,D., Jacks,T., Kamps,M.P.,
            Rose,D.W., Rosenfeld,M.G. and Glass,C.K.
  TITLE     An induced Ets repressor complex regulates growth arrest during
            terminal macrophage differentiation
  JOURNAL   Cell 109 (2), 169-180 (2002)
   PUBMED   12007404
REFERENCE   7  (bases 1 to 2752)
  AUTHORS   Ou,Q., Mouillet,J.F., Yan,X., Dorn,C., Crawford,P.A. and
            Sadovsky,Y.
  TITLE     The DEAD box protein DP103 is a regulator of steroidogenic factor-1
  JOURNAL   Mol Endocrinol 15 (1), 69-79 (2001)
   PUBMED   11145740
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jul 17, 2010 this sequence version replaced XM_227558.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.822977.1,
                                           SRR26360181.2697985.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-301               JAXUCZ010000002.1  195854796-195855096 c
            302-396             JAXUCZ010000002.1  195854312-195854406 c
            397-565             JAXUCZ010000002.1  195852506-195852674 c
            566-680             JAXUCZ010000002.1  195851833-195851947 c
            681-823             JAXUCZ010000002.1  195851572-195851714 c
            824-962             JAXUCZ010000002.1  195851309-195851447 c
            963-1021            JAXUCZ010000002.1  195851156-195851214 c
            1022-1104           JAXUCZ010000002.1  195849709-195849791 c
            1105-1210           JAXUCZ010000002.1  195849309-195849414 c
            1211-1312           JAXUCZ010000002.1  195849105-195849206 c
            1313-2752           JAXUCZ010000002.1  195847105-195848544 c
FEATURES             Location/Qualifiers
     source          1..2752
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2752
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /note="DEAD-box helicase 20"
                     /db_xref="GeneID:84473"
                     /db_xref="RGD:621744"
     CDS             1..2475
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /EC_number="3.6.4.13"
                     /note="DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20,
                     103kD; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DDX20"
                     /protein_id="NP_001178640.1"
                     /db_xref="GeneID:84473"
                     /db_xref="RGD:621744"
                     /translation="MAAAFEALPASTTSESAMAAELEAAPVPAAEPTPASPWNLRTAH
                     DIGGPRTRTGDVVLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDL
                     IVQAKSGTGKTCVFSTIALDSLILENYSTQILILAPTREIAVQIHSVITAIGIKMEGL
                     ECHVFIGGTPLSQDKTRLKKCHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLE
                     EGSFQEQINWIYSSLPASKQMLAVSATYPEILANALTRYMRDPTFVRLNPSDPSLIGL
                     KQYYQVVNSYPLAHKIFEEKTQHLQELFSKIPFNQALVFSNLHSRAQHLADILSSKGF
                     PTECISGNMNQNQRLDAMAKLKQFHCRVLISTDLTSRGIDAEKVNLVVNLDVPLDWET
                     YMHRIGRAGRFGTLGLTVTYCCRGEEENMMMKIAQKCNINLLPLPDPIPAGLMEECLD
                     CDVEVKAAMHTYSSPSISTQSPKKQVQKPERAFQSQRTPGSHMPSPRNTSVSTLSAKS
                     KHGKQKLPVKSHSECGILEKAAPPQELGCTTHPEEQVKNSVQTSTEESSSNSLHQAKE
                     TSPGSLPKIPCLSSFKVHQLSALTFAELVEDYEHYIKEGLEKPVEIIRHYTGPGAQTV
                     NPQNGFVRNRVSADRVQMLVSSSQSGDSESESDSCSSRTSSQSKGNKSYLEGSSDTQL
                     KDSECTSVGGPLSLEQIQNGNDTSTQVEYQESPETQVKARHKEGANQRSKPSRRNPPR
                     RSSYRVQTEAQEEGWHDCHRETNASSSDPYQDYEEYWRAYYRAWQEYYAAASHSYYWN
                     AQRHPSWMAAYHMNTVYLQEMMRGNQ"
     exon            1..301
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            302..396
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            397..565
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            566..680
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            681..823
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            824..962
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            963..1021
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1104
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1210
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            1211..1312
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
     exon            1313..2752
                     /gene="Ddx20"
                     /gene_synonym="Dp103"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcggcgg cgtttgaagc tctaccggcc tcgacaacct ccgaatccgc tatggcggcg
       61 gagcttgagg ccgcaccggt tccggctgcg gagccaactc ccgcctcccc gtggaacctg
      121 cggaccgctc acgacatcgg cgggccgcgc acacgtaccg gggacgtggt gctggcggag
      181 cctgcggact tcgagtcgtt gctgctgtcg cggcccgtgc tggaggggct gcgggcggcc
      241 ggcttcgaga ggccctctcc cgtgcagctc aaggccatcc cgctggggcg ctgcgggctt
      301 gatttaattg ttcaagctaa atctggcact ggaaaaactt gtgtattctc caccattgct
      361 ctggactccc ttattcttga aaactatagt actcagattt tgatattggc tcccacaaga
      421 gaaattgctg ttcagataca ttctgttatc acagccattg gaataaaaat ggaaggatta
      481 gaatgtcatg tctttattgg agggactcca ttatcgcaag ataaaaccag acttaaaaag
      541 tgtcatattg ctgttggctc tcctggtaga attaaacagc tcatagaact tgactacctg
      601 aatccaggca gtatccgtct ctttattctt gatgaagcag ataagctttt agaagaaggc
      661 agtttccagg agcaaataaa ttggatttac tcctctttgc ctgccagtaa acaaatgttg
      721 gcagtgtctg ctacttaccc tgaaattttg gctaatgctt tgacaaggta tatgagagat
      781 cccacttttg taagattgaa tcccagtgat ccaagtctga taggtttgaa gcagtactac
      841 caagttgtca actcttaccc tttggctcat aagatttttg aggaaaagac tcagcactta
      901 caggaacttt ttagtaaaat cccatttaat caagccttgg tgttttctaa tttgcatagc
      961 agagctcaac acttggctga tatcctctct tctaaaggtt ttcctactga atgcatttca
     1021 ggtaacatga atcagaatca gcgccttgat gctatggcta aactgaagca gtttcattgc
     1081 agagtcctca tttctacaga tttgacttcc cgtgggattg atgcggagaa ggtgaatcta
     1141 gttgtaaatc tggatgtgcc gttagactgg gagacttaca tgcatcgaat tggcagagct
     1201 ggccgttttg gcacattggg actgacagtg acctactgtt gtagagggga agaagaaaat
     1261 atgatgatga aaattgccca gaaatgtaat atcaaccttc tccctttacc agatcctatt
     1321 cctgctggct tgatggaaga atgcttggat tgcgatgtgg aagttaaagc tgcgatgcac
     1381 acttacagct caccaagtat atctacccag tcccccaaaa agcaagttca aaaaccagag
     1441 cgagccttcc agtctcaaag aactcctggt agccatatgc cttcccccag aaacacttct
     1501 gtatctacac tgtcagccaa atcaaagcac ggcaaacaaa agcttcctgt gaaaagccac
     1561 tcagagtgtg ggatcctaga aaaggcagct ccaccacagg agttgggctg taccacacat
     1621 ccggaagagc aagttaagaa ctctgttcag acctctactg aggagtcctc cagtaacagc
     1681 ctgcaccagg ccaaagagac ctcacctggg tcactcccta agattccttg tctgtcttcc
     1741 tttaaagtcc atcagctgag tgctttgact tttgcagaac tggtagaaga ttatgaacac
     1801 tatattaaag agggcttaga gaaacctgtg gaaattatcc ggcactacac aggacctggg
     1861 gctcagactg tgaatcctca gaatggtttt gtgagaaaca gagtttctgc agacagagtg
     1921 cagatgttgg tgagtagtag ccagtctgga gactcagaga gtgagagcga ctcttgcagc
     1981 tccaggactt cttcccagag caaaggcaat aagtcttact tggaaggctc ttctgacact
     2041 cagttgaaag actctgaatg tacttctgtg ggtggccctc tgtctttgga acaaattcag
     2101 aatggaaatg atacctcgac tcaagtggag tatcaagaat cccctgaaac ccaggtaaag
     2161 gcaaggcata aagaaggtgc taaccaaagg tctaaaccaa gtcggagaaa cccaccacgg
     2221 cgctcctcct accgagtaca gacagaagcc caggaagagg gttggcatga ctgtcacagg
     2281 gaaacaaacg cgagttcttc agatccctac caggattatg aggagtactg gagagcgtat
     2341 tacagggcat ggcaagaata ttatgctgct gcttcccatt catactattg gaatgctcag
     2401 agacatccga gctggatggc tgcctatcat atgaatacag tttatctaca agaaatgatg
     2461 cgtggtaacc agtgaggtta gcatgtgcct gagactgttg actgtcaaca gatcattaga
     2521 tacacattct tcacctagag caagtaggat tcggtggcat tttggaggaa cttgagagga
     2581 cttgaggctt tctactggga cacaattatt tttcagatta tttttagaac ttggctctaa
     2641 agaccccccc aaggtgccac ttcatgtagg ctggtcccaa aagaaacctt taaataggtg
     2701 acatatgcca ctccttactt aaaaaacaaa ataaaaacag ttaaaatttg aa
//
