LOCUS       NM_001106820            3356 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus DEAD-box helicase 10 (Ddx10), mRNA.
ACCESSION   NM_001106820 XM_001071986 XM_236263
VERSION     NM_001106820.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3356)
  AUTHORS   Palmer K, Fairfield H, Borgeia S, Curtain M, Hassan MG, Dionne L,
            Yong Karst S, Coombs H, Bronson RT, Reinholdt LG, Bergstrom DE,
            Donahue LR, Cox TC and Murray SA.
  TITLE     Discovery and characterization of spontaneous mouse models of
            craniofacial dysmorphology
  JOURNAL   Dev Biol 415 (2), 216-227 (2016)
   PUBMED   26234751
REFERENCE   2  (bases 1 to 3356)
  AUTHORS   Martin R, Straub AU, Doebele C and Bohnsack MT.
  TITLE     DExD/H-box RNA helicases in ribosome biogenesis
  JOURNAL   RNA Biol 10 (1), 4-18 (2013)
   PUBMED   22922795
  REMARK    Review article
REFERENCE   3  (bases 1 to 3356)
  AUTHORS   Baltz AG, Munschauer M, Schwanhausser B, Vasile A, Murakawa Y,
            Schueler M, Youngs N, Penfold-Brown D, Drew K, Milek M, Wyler E,
            Bonneau R, Selbach M, Dieterich C and Landthaler M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 3356)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_236263.4, XM_001071986.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3356
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q24"
     gene            1..3356
                     /gene="Ddx10"
                     /note="DEAD-box helicase 10"
                     /db_xref="GeneID:300710"
                     /db_xref="RGD:1308990"
     exon            1..322
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..2761
                     /gene="Ddx10"
                     /EC_number="3.6.4.13"
                     /note="DEAD (Asp-Glu-Ala-Asp) box polypeptide 10"
                     /codon_start=1
                     /product="probable ATP-dependent RNA helicase DDX10"
                     /protein_id="NP_001100290.1"
                     /db_xref="GeneID:300710"
                     /db_xref="RGD:1308990"
                     /translation="MGKTVGSLGQGTRPDPVRSFNRWKKKHSHRQHQKKERRKQLKKP
                     EWQVEREGISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGL
                     ALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEV
                     LRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETICFHATNLQM
                     LVLDEADRILDMGFADTMNAIIENLPKKRQTLLFSATQTKSVKDLARLSLKDPEYVWV
                     HEKAKYSTPATLEQNYIICELHQKISVLFSFLRSHLTKKSIVFFSSCKEVQYLYRVFC
                     RLRPGISILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDC
                     PEDANTYIHRAGRTARYKEDGEALLILLPSEEQGMVQQLLQKKVPVKEIKINPEKLID
                     VQKRLESFLAQDQDLKERAQRCFVSYIRSVYLMKDKEVFDVNKLPITEYALSLGLAVA
                     PRIRFLQKMEKQPNKELGKNQVTEAIQPRAPSLTSDEVEEFRAYFSEKMSILHKSGKR
                     LEETEHSLASGESEEQDEETEDEEMEDHVGQTREPPTDSVPRSEEAQKVKEVPVQFLD
                     RDDDEEDGPDADFLTVKRRDVFGLDLKENEALSKKEPSKSSVKKKLTKVAEAKKVMKR
                     NFKVNKKITFTDEGELVQQWPQIQKCATNDVEEEDDTGGINLDKAKERLQEEDKFDKE
                     EYRKKIKAKHRERRLKEREARREANKRQAKARDEEEAFLDWSDEDDGGFDPSTLPDPD
                     KHRSSEESESEDTKHKMSDTKKKQEMRKRNNTEVDDVRPRSRHGKKAKWETLEPLDTG
                     LSLAEDEELVLHLLKSQN"
     exon            323..383
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            384..514
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            515..673
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            674..794
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            795..984
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1111
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1112..1274
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1275..1359
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1461
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1462..1549
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1638
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            1639..2107
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            2108..2227
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            2228..2389
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            2390..2446
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            2447..2583
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
     exon            2584..3356
                     /gene="Ddx10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttgggggcg ggtccccggc cttgcgcgtg cgtccctgca ccctctccac acgctgggtt
       61 tcgcgtcttc cttgctgctc ctgaggagat aggtgtctcg tgtctggcgg cgtcgtgcgt
      121 cctggtagcc cccgccatgg gcaaaacggt tggttctctg ggtcagggaa cccgaccgga
      181 cccggtgagg agcttcaacc gctggaagaa aaaacacagc cacaggcagc accaaaagaa
      241 ggaacggagg aagcagctta agaagccgga atggcaggtc gaacgtgagg gtatcagccg
      301 cctcatgcaa aattacgaga agataaatgt aaatgaaatt acaagatttt cagatttccc
      361 tttatccaaa aaaacgttga aaggtttgca agaagcgcaa taccgcttgg taacagagat
      421 acagaagcag accatagggt tggctttgca aggtaaagat gtgcttggag ctgccaaaac
      481 tgggtctggc aagactttgg cttttctcgt tccagtattg gaagccttat accgcctgca
      541 gtggacttca acagacggcc tgggagttct gataatatca cctactcgag aactggccta
      601 tcagacattt gaggttctac gcaaagtagg aaagaaccat gatttttcag ctggtctcat
      661 cattggtggg aaggatctaa aacatgaagc tgagaggatc aacaacataa atatactcgt
      721 ttgcacacca ggtcgacttc ttcaacacat ggatgaaaca atctgttttc atgccaccaa
      781 tcttcagatg ttagttcttg atgaggcaga cagaatctta gatatgggct ttgctgatac
      841 catgaatgct atcattgaaa atcttcccaa gaaacgccag actttgctgt tctcagctac
      901 acagaccaaa tctgtgaagg accttgcgcg cttgagtttg aaagaccctg agtatgtctg
      961 ggttcatgag aaagcaaaat atagcacccc tgctacattg gaacagaact atataatttg
     1021 tgagctgcac caaaaaataa gtgtgctgtt ttcatttttg agaagccacc taacgaagaa
     1081 gagtattgtg tttttctcca gttgcaaaga ggtgcagtat ctgtacaggg tgttctgccg
     1141 gctgcgccca gggatctcta tccttgctct ccatggccgg cagcagcaga tgcgaagaat
     1201 ggaagtctac aatgaatttg tccgaaagag ggctgcagtc ctttttgcta ctgatattgc
     1261 agccagggga ttggattttc cagctgtgaa ttgggtcctt cagtttgatt gtccagagga
     1321 tgccaacacg tatattcaca gagctggtag aactgccagg tacaaggagg acggagaagc
     1381 gttattaatt ttactgccct ccgaagaaca aggcatggtg cagcagcttc tccagaagaa
     1441 agttcctgtg aaggagatca aaatcaatcc agaaaaactt atcgatgttc agaaaagatt
     1501 agaatcattt ttagctcaag atcaagattt aaaagaaaga gctcaaaggt gttttgtctc
     1561 ctacatacgt tcagtatatc ttatgaagga taaagaagta tttgatgtga acaagttacc
     1621 tattactgaa tatgcactgt ctcttggtct tgctgtggca ccacggataa gatttcttca
     1681 gaaaatggag aaacagccca acaaagaatt gggaaagaat caagtcactg aagcaattca
     1741 gcccagggct ccctccctca ccagtgatga agtagaagaa tttcgagctt atttcagtga
     1801 gaaaatgtcc atccttcaca aaagtgggaa aagactagaa gagacagaac acagcttggc
     1861 tagtggtgag agtgaagaac aggatgaaga gacggaagat gaagaaatgg aagatcatgt
     1921 gggacaaaca agagagcctc ccactgactc tgttcccagg agtgaggagg cacagaaggt
     1981 caaggaagtt cctgtgcagt tcttagacag ggatgatgat gaggaagatg ggcctgatgc
     2041 tgacttcctc acagtgaagc ggcgtgatgt gtttgggttg gatcttaaag agaatgaagc
     2101 actgtcgaaa aaggaacctt ctaaatccag tgtcaagaaa aaattaacca aagttgcaga
     2161 agcaaaaaaa gtaatgaaga gaaattttaa agtgaacaag aaaataacat ttacggatga
     2221 aggagagttg gttcagcagt ggccacagat tcagaaatgt gctacaaatg atgtggagga
     2281 agaagatgac actggtggca tcaacctaga caaagccaaa gaaaggcttc aggaagagga
     2341 caaatttgac aaagaagaat ataggaagaa aattaaggca aagcatcggg aaagacgctt
     2401 aaaagagaga gaggccagaa gagaagccaa caaaagacaa gcaaaggcca gagatgaaga
     2461 ggaagccttt ctggactgga gtgatgaaga tgatggtgga tttgatccaa gcacacttcc
     2521 agatccagat aagcacagaa gttctgaaga atcagagagt gaagatacaa aacacaagat
     2581 gagtgacacc aagaagaagc aggaaatgag gaagagaaac aacactgaag tcgatgatgt
     2641 aagaccaaga agtcgtcatg gaaagaaggc caagtgggaa acgttagaac ctttggatac
     2701 aggcctgtct ttagcagagg acgaagagct ggtgttacat ctcctcaaaa gtcaaaacta
     2761 agtgttctct gtgcctctgt gcacctcgat acctctggac attactatgt gggcaagaag
     2821 ttaaaaacag ctttggggca cttaggtact gtgtgtcctt tctccaacag aagtgaccac
     2881 attctaagct ttacaagctg agttttgaaa tatcgaggaa catactcaga gtaagaacat
     2941 gttgtatact ctgttaggat gtatgtgtag gttcatattc cccaccactg gaaatgcttg
     3001 tcttgtttgt tcccacagtg ctgaagagtg aaccaaggcc gtgcatgtgg tagatgagtg
     3061 ctctcctccc gagctgtgta cctagtccgg cttgtttgtt ttacaggcaa ggctctgaat
     3121 cgttgttcat ttgcaaatac ctatattcat acagtacaaa aaatttaatg ttactcttaa
     3181 gtatacataa ttttgtgtat attatctcca aagaaacagt ataatggact agccctgaca
     3241 aagaatattt tttgcgttca taaaaaataa acatttctta taaagtacta ttgttttcat
     3301 tgtgtccagt gatatgaaaa actcaaaaat agattcataa aattaaatca tgacaa
//
