LOCUS       NM_001126294            3368 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus DNA damage-induced apoptosis suppressor (Ddias),
            mRNA.
ACCESSION   NM_001126294 XM_001062994 XM_574490
VERSION     NM_001126294.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3368)
  AUTHORS   Won KJ, Im JY, Yun CO, Chung KS, Kim YJ, Lee JS, Jung YJ, Kim BK,
            Song KB, Kim YH, Chun HK, Jung KE, Kim MH and Won M.
  TITLE     Human Noxin is an anti-apoptotic protein in response to DNA damage
            of A549 non-small cell lung carcinoma
  JOURNAL   Int J Cancer 134 (11), 2595-2604 (2014)
   PUBMED   24214091
REFERENCE   2  (bases 1 to 3368)
  AUTHORS   Nakaya N, Hemish J, Krasnov P, Kim SY, Stasiv Y, Michurina T,
            Herman D, Davidoff MS, Middendorff R and Enikolopov G.
  TITLE     noxin, a novel stress-induced gene involved in cell cycle and
            apoptosis
  JOURNAL   Mol Cell Biol 27 (15), 5430-5444 (2007)
   PUBMED   17515607
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166470.1.
            
            On or before Jul 13, 2008 this sequence version replaced
            XM_574490.2, XM_001062994.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166470.1, EV774624.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3368
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..3368
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /note="DNA damage-induced apoptosis suppressor"
                     /db_xref="GeneID:499204"
                     /db_xref="RGD:1559690"
     exon            1..72
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
     exon            73..156
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
     exon            157..285
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
     CDS             173..2824
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /note="nitric oxide-inducible gene protein"
                     /codon_start=1
                     /product="DNA damage-induced apoptosis suppressor protein"
                     /protein_id="NP_001119766.1"
                     /db_xref="GeneID:499204"
                     /db_xref="RGD:1559690"
                     /translation="MNRRRKFLFASVLALQNSSFIYPSCQRCFSRIFLESKRFTCPKC
                     GCTGDAESANYRYRLSLKVAESNTLFVITVFGSCLDTYFGLTATGLHRYLKDSSKIPE
                     TLDSGRTQSLLTTAVEKCFVGQSFVFGVTNFGDVCGHHSNCSNFQQPCCKHRGEVRTL
                     VASQIVLPDPRVTGFTVIDYLHPLLHRKHHCDSQDHSSQSLTSDHSDSEFNSIQGSGN
                     TSWVLESSREDFFRFWQPSLELTSTDSHITSNDDFPPSEQLVASGTPTQNGHCVSFSE
                     VTSSNNCHDSLQSLWSFVSCMDKNNTTGKLGEELGLLSPICSSCHESRLTDSNFFPSQ
                     MQKPFKEHNLECYSKAEKNDYSQYDIPCYQHREVNTTILQQGSSAFSLSSLKPEETAS
                     ASQKSDSLIWDDIPFSESLNKFLAVVESEIAVAEIDTQNRKQGTDNSTDKCHKNYSRL
                     SLTPLRDTRALNTPPFGLRSSQAMRENSRREAFFYNSKSSSSSQIQRESHPDKAAAAV
                     SIGSNRSDISKDFLPDTCSSALFTSSDDMEASISQKRTSGVLQQRNEISCRLRTSISD
                     CSDLSNSCFTGCEEKSHSGTKEKLAIQNCSKKYNDVSDLHKLENKRSYRWPEKQDDNF
                     TISRKLTYPLETFRGSPKSISKEKPYRPSNNNLTQSSSADHEGSYNASADLFDDFAKD
                     KDTETEITKLPQDILLPLEASCTENYPINENCNHPSQKLSLQSISPSEYQRPSSQSDS
                     ECDFEESQEDFVPCSQSTPVAGFHQRIHGLNGASKILPSFYSHLNANYKNTNISPLTG
                     KCQATPTCPKNVKTSTQKLNHCPAAECLENDMDEWVPPTTKKVFISDVCGLRVTCLRK
                     CLAVHYSPDQKELPRKKLIKVTHKTNK"
     exon            286..447
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
     exon            448..565
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
     exon            566..3340
                     /gene="Ddias"
                     /gene_synonym="noxin; RGD1559690"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttggagagcg gctgtccggg aggccggagt tccttcatgg ttgcccgggc ttgcctgggt
       61 cctttgcttc agataaaatt ttaagtgcct cccattatgc caagaagggc caggttttgg
      121 atgacttcaa ttaccaatag agactgctgt cctagggaca agatagaggc acatgaatag
      181 aagacggaaa ttcctttttg cctcagtact tgctctccag aattcgagtt ttatatatcc
      241 atcatgtcaa aggtgcttct ccaggatatt ccttgagtcc aaaaggttta cttgtcccaa
      301 gtgtggctgt accggtgatg ctgagagtgc caactacaga tatagactgt ccttgaaagt
      361 ggcagagtcc aacacgttat ttgtcattac tgtgtttggg agctgcttag atacttattt
      421 tggactcact gctactggtt tacacaggta ccttaaggat tctagtaaaa tcccagaaac
      481 cctggacagt ggtagaactc agagcctgtt gaccacagca gtagaaaagt gttttgttgg
      541 acaaagcttt gtgtttggag taacgaactt tggagatgta tgtggacacc attccaattg
      601 cagtaacttc cagcagcctt gctgtaagca cagaggagaa gtcaggacac tcgtagcctc
      661 ccagatcgtc ctgcctgacc cgcgtgttac aggcttcact gtcattgact atttacatcc
      721 gcttttacac aggaaacatc actgtgactc tcaggaccat agcagccagt cactcacttc
      781 agatcactca gacagcgagt tcaacagcat acagggctct gggaatacat cctgggtttt
      841 ggagtctagc agagaggact ttttcagatt ctggcagcca tctcttgagc tgacgtctac
      901 tgattcacac ataacatcta atgatgactt cccaccttca gaacagctcg tggccagtgg
      961 tactcctacc caaaacggac actgcgtctc cttctctgag gtcactagtt ctaacaactg
     1021 ccacgattcc ctccagagtt tatggagctt tgtttcttgt atggacaaga ataatacaac
     1081 aggaaagttg ggtgaagaat taggtttact gagtccaatt tgcagcagtt gtcatgaaag
     1141 tagactgact gactctaatt ttttcccttc acaaatgcaa aaacccttta aggaacataa
     1201 tttagaatgc tatagtaaag cagaaaaaaa tgattactcc cagtatgata tcccatgtta
     1261 ccagcatcgt gaagtaaata ccaccattct tcaacaggga tcttctgcat tttcattgtc
     1321 atcactgaaa cccgaagaaa cagcgagtgc ttcccagaag tctgactcct tgatttggga
     1381 tgatatacca ttctctgaaa gcctgaacaa gtttctagca gttgttgaaa gtgagattgc
     1441 tgtagctgag atagatactc agaatagaaa gcagggtaca gataacagca ctgataaatg
     1501 ccacaaaaac tacagcagat tatcattgac tcctctgaga gatactagag ccttaaatac
     1561 gccgcctttc ggcttaaggt catcacaagc aatgagagaa aactcaagga gagaggcctt
     1621 cttttataac agtaagtcta gttcaagttc tcaaatccaa agagaatcac atccagacaa
     1681 ggcagcagcg gctgtctcta taggcagtaa taggagcgat atctccaagg attttctacc
     1741 agatacttgt tcatcagctc tgtttacatc ttcagatgac atggaagcct ccattagcca
     1801 aaagaggact agtggggtcc tgcaacaaag gaatgaaatt tcgtgcaggc tcagaacctc
     1861 aataagtgac tgttctgatc tcagtaacag ctgttttact ggatgtgaag aaaaatcgca
     1921 ttcaggaaca aaagaaaaat tggcaataca aaactgttct aaaaaataca atgatgtttc
     1981 tgatcttcac aaattagaaa ataagcggag ttatagatgg ccggaaaagc aagatgacaa
     2041 tttcacaatt agccggaaac tcacatatcc tttagagacc tttcgcggga gcccaaaaag
     2101 catatcaaaa gaaaagcctt ataggcctag caataataac ttaacacaaa gttcttctgc
     2161 tgatcatgaa ggcagctaca atgcttctgc tgatcttttt gatgattttg ctaaagataa
     2221 ggacactgaa acagaaatta ccaaactacc gcaagatatt ttgttaccac tggaagcatc
     2281 ttgcacagaa aattatccta taaatgagaa ctgcaaccat ccttcacaaa aactctcctt
     2341 gcaaagcata tcaccctcag agtatcaaag accaagctct cagtcagact cagaatgtga
     2401 ttttgaagaa agccaagaag actttgttcc atgttcacag tcaactccag ttgcaggctt
     2461 ccaccaaaga attcatggct taaatggtgc ttccaaaata ctgccttcct tctattcaca
     2521 tcttaatgct aattataaaa acacaaacat ttctcctcta actggcaaat gtcaagccac
     2581 cccaacctgc ccaaagaatg taaaaacatc tacgcagaag ctcaaccact gccctgctgc
     2641 tgagtgcctt gaaaatgata tggatgaatg ggtcccccct actactaaaa aagtatttat
     2701 ttcagatgtt tgtggattga gagtcacgtg tttaagaaaa tgccttgctg tccattattc
     2761 ccctgaccaa aaagagttac caaggaagaa actgataaaa gtcacacata aaaccaacaa
     2821 ataattaaga agttaaagac tatattttgt accaataatt acaaaaccaa aagtgtctta
     2881 agtgtgattg taaatgatca ggctgaaagt aggaaaagtc catttgggga tggcctttca
     2941 ggagtcaagt ggaagtcatc ttcccttttc ataatacttc agtgtctgat aaaaaaagta
     3001 cttggtttac tcaaagtatt tccatataaa gtcataggaa tccagttccc agaaatttta
     3061 agcaatggca aatctatttg gaaatttttg ctttcactga tacagagagc agtctatatt
     3121 ttgaacactt acagaaagtc attaatagaa aatggactgt actgtgtgct gttggatctt
     3181 tcaagatttt caccatggct ttttttttcc tccagaatac tgtaatttag ataactgagc
     3241 acttttcctt acattgactg tattaatatg ttggttttgt atatttaaaa gtatttgtta
     3301 aaatatagac atacagaaat aaagtcttta caaattaaaa aaaaaaaaaa aaaaaaaaaa
     3361 aaaaaaaa
//
