LOCUS       NM_001395100            4589 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus defective in cullin neddylation 1 domain
            containing 1 (Dcun1d1), mRNA.
ACCESSION   NM_001395100
VERSION     NM_001395100.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4589)
  AUTHORS   Scott,D.C., Hammill,J.T., Min,J., Rhee,D.Y., Connelly,M.,
            Sviderskiy,V.O., Bhasin,D., Chen,Y., Ong,S.S., Chai,S.C.,
            Goktug,A.N., Huang,G., Monda,J.K., Low,J., Kim,H.S., Paulo,J.A.,
            Cannon,J.R., Shelat,A.A., Chen,T., Kelsall,I.R., Alpi,A.F.,
            Pagala,V., Wang,X., Peng,J., Singh,B., Harper,J.W., Schulman,B.A.
            and Guy,R.K.
  TITLE     Blocking an N-terminal acetylation-dependent protein interaction
            inhibits an E3 ligase
  JOURNAL   Nat Chem Biol 13 (8), 850-857 (2017)
   PUBMED   28581483
REFERENCE   2  (bases 1 to 4589)
  AUTHORS   Kim,A.Y., Bommelje,C.C., Lee,B.E., Yonekawa,Y., Choi,L.,
            Morris,L.G., Huang,G., Kaufman,A., Ryan,R.J., Hao,B., Ramanathan,Y.
            and Singh,B.
  TITLE     SCCRO (DCUN1D1) is an essential component of the E3 complex for
            neddylation
  JOURNAL   J Biol Chem 283 (48), 33211-33220 (2008)
   PUBMED   18826954
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1952908.1,
                                           SRR26360194.1212639.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-56                JAXUCZ010000002.1  120695937-120695992 c
            57-273              JAXUCZ010000002.1  120684174-120684390 c
            274-442             JAXUCZ010000002.1  120682154-120682322 c
            443-573             JAXUCZ010000002.1  120679496-120679626 c
            574-656             JAXUCZ010000002.1  120654728-120654810 c
            657-753             JAXUCZ010000002.1  120654411-120654507 c
            754-4589            JAXUCZ010000002.1  120649445-120653280 c
FEATURES             Location/Qualifiers
     source          1..4589
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q25"
     gene            1..4589
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /note="defective in cullin neddylation 1 domain containing
                     1"
                     /db_xref="GeneID:310324"
                     /db_xref="RGD:1309668"
     exon            1..56
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..833
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /note="testis derived transcript 3; DCN1, defective in
                     cullin neddylation 1, domain containing 1; DCN1-like
                     protein 1-like"
                     /codon_start=1
                     /product="DCN1-like protein 1"
                     /protein_id="NP_001382029.1"
                     /db_xref="GeneID:310324"
                     /db_xref="RGD:1309668"
                     /translation="MNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNF
                     FQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQFCDDLALDPASISV
                     LIIAWKFRAATQCEFSKQEFMDGMTELGCDSVEKLKAQIPKMEQELKEPGRFKDFYQF
                     TFNFAKNPGQKGLDLEMAIAYWNLVLNGRFKFLDLWNKFLLEHHKRSIPKDTWNLLLD
                     FSSMIADDMSNYDEEGAWPVLIDDFVEFARPQISGTKSTTV"
     exon            57..273
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     exon            274..442
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     exon            443..573
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     exon            574..656
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     exon            657..753
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
     exon            754..4589
                     /gene="Dcun1d1"
                     /gene_synonym="Tes3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtccattcgc tgcggagccg gaggaggagg ggagaggtcc ggaggacacc aacatgaaca
       61 agttgaaatc atcgcagaag gataaagttc gtcagtttat gatcttcaca caatctagtg
      121 agaaaactgc agtaagttgc ctttctcaga atgactggaa gttagatgtt gcaacagata
      181 atttttttca aaatccagaa ctttatatac gggagagtgt aaaaggatcg ttggacagga
      241 agaagttaga acaactgtac aatagataca aagaccctca agatgaaaat aaaattggaa
      301 tagatggtat acagcagttc tgtgatgacc tggccctcga tccagccagc atcagtgtgt
      361 tgatcattgc atggaagttc agggcggcca cacagtgcga gttctccaaa caggagttca
      421 tggatggcat gacagagtta ggatgtgaca gcgtagaaaa actaaaggcc caaataccca
      481 agatggagca agaattgaaa gaaccaggac gatttaagga cttttaccag tttactttta
      541 attttgcaaa gaacccagga caaaaaggat tagatctaga aatggccatt gcttactgga
      601 acttagtgct taatggaaga tttaaattct tagacttatg gaataaattt ttgttggagc
      661 atcataaacg atcaatacca aaagacacgt ggaatcttct gttagacttc agttcaatga
      721 ttgcagatga catgtccaat tacgatgaag aaggagcatg gcctgttctt attgatgact
      781 ttgtggaatt tgcacgccct caaatttctg ggacaaaaag tacaacagtg tagcactaaa
      841 ggaaccttct agaatgtaca tagtctgtac aataaacaca acggaaaaat gcacagtcaa
      901 tttctgctgg ctggactgaa ctgaagatca atcctcatag ttcaaactga gggttgagac
      961 aaaactttaa ggatacatct cggacctacc gtactccatt cttctgctgg tggtttgggc
     1021 ttgtcttcta gtctgggcca ctctaaacat ttataatcca acattgtgga ttccatctta
     1081 aacctgtgga ccatcttagt ttgtcttccc ataagtcata gacgcttgat ggggattatt
     1141 ttgaggtttc cattcttgca taaagcacaa tgctgtcttc atcagaaaac agtttggcat
     1201 aagaattaaa cataataatg aacaccacaa acaatttata aaaacttgtt aagtatatgc
     1261 tttgggctag ttgcaaagac tatgctgtag cacttcaact gagagtgtta tctgagtgta
     1321 ccgcatctgg agtggtgttt gatttggggg aatttagttt tcctggcaaa ccatatgcac
     1381 tgttggtgtg agtagaatac ctgataaaga cgtgtcaaaa taaccaacac ataaaaaaag
     1441 gataatttga tgactccctg aaatatgccc tgtgtttcag actctcgcga aggttctaca
     1501 aaacaagtct gtggctgtct tacccgtgtg tacacagtgt cctacagtga gctttgattt
     1561 aaagtattgt aatgagacgg aatgttagac cccactcatg tgcacccata caccacatca
     1621 ttggattcca ttacgcttgg agaggcttct atgcctttcg aataagttaa actatttcat
     1681 tggttttgaa tgttttggat tgctatacaa tataatactc taaatttagg catgagggtt
     1741 ttaggtttgg ggtttttttt gtttttgttt ttgtttttta attttttgtc atcgcacaat
     1801 ggaacacaat gcaattcact taatttataa gaagacagta agatttaaat tttcaaaatg
     1861 gttgtgatga gccgtgaagt tcaccctttc tcatgtggca ctgctctttc aggcagttgg
     1921 ccagccctgc tgacggctgg ctgctgaaat ggctttactg ctaaatcact gtggttgcca
     1981 agtctttact ccaagagcgg agattgtcag acaggcgagc actggtgcag aataccaatg
     2041 gcttctgttg tataaattat ttgacttttg actgtttttg tttcccttgc atttgctatt
     2101 tccacatcaa agcagaatgc agtcttgatt gtttgttttg gttttgggtt tttttttttc
     2161 tatgacagga ctcacgaatt gctctcctgc tgaaaatgct tgtttgtctg ttaacacact
     2221 gacacgtgta ttcataaata tctccatgag gaagttaaaa tgatgaccta aatgttgggt
     2281 gactggtctt cagtaggaac agattttgct tcatgtatcc aggtcctctg cagggtacta
     2341 aggagtgttc ctcagaatag cagaacagtt tatgcagata tggaaatgat taaaactgct
     2401 ttctagtcac atgatttgga gaatgcatag aaaacttaca tatcattaat ccaatcataa
     2461 ctttaattga ggaatgcatt tctaccaaaa gaagcttaga gtaaatttct attcatgtta
     2521 cagggattgg ttattaaaag aaaatagaat cttgctgttt tcagtatttc ttgattttat
     2581 ttttgtaaat atgaagaact tcaattatga aaaaaattaa agatatatgt gtatatatat
     2641 acatatatat atatatatat atatatatct ttaaaagttt tgcagaccta tattgtttat
     2701 tccctacgtg gaacattttg agttcttggt attgttttca gattgattga ttcagatacg
     2761 atttgttttc aaatgagact ccattagctt ctttccctgc ctcataaatt tttttttcat
     2821 aaaaatcttg atatttgtgt gtggcctaat gctttgggtt ttacagattt tatttttaaa
     2881 tgcaagactt tggaacaaaa tagtgattgt catcagtttg gcactaaaca tttacaatta
     2941 ctgtgtaatt ataaacaaaa atatataaag cttttgatta tgtagcaaaa aacgttaagg
     3001 ctgttcacag tgatggcatc ttagaattaa aaccattgct agggctcaaa caagaaagtt
     3061 gatttaatgt gtttattctg agggtgaatg tctggttata gggaatgttt tgtactaaaa
     3121 atgcttaccc tgctggggga ggggcgtcgg tgagtctgag agagaggcca tgtgcgtaca
     3181 cagcgagctc tactgcttca gttcatgggg tctttgggtg aggtttccaa gctgattact
     3241 ttcttttttt agacagagcc acaaggagag tttacttttt gccaaatgtc ataacaggta
     3301 cacattttta aatgtaaagc tttttaaata gtaaaatgta taaaatgaga agtacccaca
     3361 tataaaaata cttggtcaag gttctcttca tctgcatatc tctgtaagtt caagtgtgtc
     3421 tttccaaccc ctgtcatatt acccacggag gcaataaaag cttcagtaaa tttgccatga
     3481 ctaaatcctt tacatcttat ttcagtgttt cagagtttca caaagctaga ctatacttga
     3541 ggacgtttgc agaagagtca tgatagacga actctagtgg ctcctctggg ggagagaagc
     3601 tatgccaagt gcacactcgt gtccacgact gctcgccgcg actgctcacc gcacggtcat
     3661 ctgactgtgt tgttgtttgc ggcagcgttg tgagtgtgca tccgtcgtcc tgctttttaa
     3721 aagtttagtg acagtaaatt cactcagcaa aaacgtcaga agccttttat gtaatctctt
     3781 tcctgaacat tctttttttt ttttaaagta cttaaccctt catccttttt tttaatttat
     3841 tatgtatatg aatacactgt agctatatct tcagacacca gaagagggca gcagatctca
     3901 ttacagatgg ttgtgagcca ccatgtggtt gctgggaatt gaactcagga cctctggaag
     3961 agcagtcagt gctcttaacc gctgagccat ctctccagcc ctcctgaaca attcttagac
     4021 aagatagacg actcttttcc tcagagatct actgtagtta tttatttttt cctttgatga
     4081 taagttttga gtcattccat gcccactctg cttaggggtt taggtgtgtt actgttaagg
     4141 actgctggtt ggaaacctgt aattttggca tacaaataga agaaacaagt tgacctaaga
     4201 ataattttgg gattaaaaat gggaaaatgg tgttgggaaa aattacaatt gtttacaaag
     4261 tatgcctttg taaaataaat caacttttag tgagaattta tgtggctctg aatgttaaac
     4321 tgtatttaat aggaaatatt tacctgacat ctctgggctt ttttttgttg ttgttattgt
     4381 tgttacctta aactttgaat aatatgattt atattgaatg ctgagatgtt ttgataagag
     4441 tttatcaaat ttgataatgt aatgataaat gttttaaaat gtgaactatt tatcttaata
     4501 actgaattgt ggtttttata taacagatga cggatagggt cacactggct caccatttaa
     4561 ttgattataa acttgagtgt atttctgaa
//
