LOCUS       NM_001037778            1623 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus dynactin subunit 5 (Dctn5), mRNA.
ACCESSION   NM_001037778 XM_219310
VERSION     NM_001037778.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1623)
  AUTHORS   Li,Y., Klena,N.T., Gabriel,G.C., Liu,X., Kim,A.J., Lemke,K.,
            Chen,Y., Chatterjee,B., Devine,W., Damerla,R.R., Chang,C., Yagi,H.,
            San Agustin,J.T., Thahir,M., Anderton,S., Lawhead,C., Vescovi,A.,
            Pratt,H., Morgan,J., Haynes,L., Smith,C.L., Eppig,J.T.,
            Reinholdt,L., Francis,R., Leatherbury,L., Ganapathiraju,M.K.,
            Tobita,K., Pazour,G.J. and Lo,C.W.
  TITLE     Global genetic analysis in mice unveils central role for cilia in
            congenital heart disease
  JOURNAL   Nature 521 (7553), 520-524 (2015)
   PUBMED   25807483
REFERENCE   2  (bases 1 to 1623)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   3  (bases 1 to 1623)
  AUTHORS   Schroer,T.A.
  TITLE     Dynactin
  JOURNAL   Annu Rev Cell Dev Biol 20, 759-779 (2004)
   PUBMED   15473859
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Dec 7, 2020 this sequence version replaced NM_001037778.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098764.1, FQ099640.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-120               JAXUCZ010000001.1  186120415-186120534
            121-189             JAXUCZ010000001.1  186121504-186121572
            190-308             JAXUCZ010000001.1  186122187-186122305
            309-420             JAXUCZ010000001.1  186126847-186126958
            421-523             JAXUCZ010000001.1  186133076-186133178
            524-1623            JAXUCZ010000001.1  186136047-186137146
FEATURES             Location/Qualifiers
     source          1..1623
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..1623
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /note="dynactin subunit 5"
                     /db_xref="GeneID:308961"
                     /db_xref="RGD:1305654"
     exon            1..120
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..621
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /note="dynactin 5 (p25)"
                     /codon_start=1
                     /product="dynactin subunit 5"
                     /protein_id="NP_001032867.2"
                     /db_xref="GeneID:308961"
                     /db_xref="RGD:1305654"
                     /translation="MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMN
                     DCIIRGDLANVRVGRHCVVKSRSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAA
                     QIGSYVHVGKNCVIGRRCVLKDCCKILDNTVLPPETVVPPFTVFSGCPGLFSGELPEC
                     TQELMIDVTKSYYQKFLPLTQV"
     exon            121..189
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
     exon            190..308
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
     exon            309..420
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
     exon            421..523
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
     exon            524..1623
                     /gene="Dctn5"
                     /gene_synonym="RGD1305654"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaccggaagt agctagaatc accggcagcc tgagcgactg acaggatcct gaggttcaga
       61 gaggaggcag ccatggagtt gggcgaactg ctgtataaca agtccgagta catcgagacg
      121 gcatctggga acaaagttag tcgccagtct gttttgtgtg gaagccagaa catcgttctc
      181 aatggcaaga ccattataat gaatgactgt atcatccgag gagacctggc aaatgtaaga
      241 gttggacgtc actgtgttgt gaaaagccgt agtgtcataa ggccaccgtt caaaaaattc
      301 agcaaaggtg ttgcattctt tcctctgcat attggggatc atgtctttat tgaggaagac
      361 tgtgtggtca acgctgccca gattggttct tatgttcacg ttgggaagaa ctgtgtgatt
      421 gggcgccggt gtgtcttgaa agactgctgc aaaattcttg acaatacagt attacctcca
      481 gaaactgtgg tccccccatt cactgtcttc tccggctgtc caggactctt ctcaggggag
      541 ctcccagagt gcacacagga gctgatgatc gatgtcacca aaagctacta ccagaagttt
      601 ctacccctaa cacaagtcta gtgtctgtgc ctcacgcctt taattcttct gaactccaag
      661 atggacctgg agatgagaag ggcagttggt gacgacagag ctgctgtgtt cacacaactt
      721 tactctcctg gttggtgggg tttttgtttt ggtttggttt ttaatttaga agttttcaat
      781 cttccatgga tctgagcatt taagaattta aaagaagact ggagagatgg ctcagtggtt
      841 aagcatgctg gttgctcttc cagaggaccc agattcagtt cctagcaccc acatggccct
      901 acaactgtct gtaactcttg ttccagagga tctgatgggt ttctggcttc catggtcacc
      961 aaacgtacac atggtaaaga catatatgca gccaaaatat cccttcacat aaaataacga
     1021 actttttaaa gaattttaat aagaacatct ggaagagttg tctttataca ccgtgcttac
     1081 acctgtcaac agtcaccata ccattgtctg aagaggacag aaagttctgt tgctgacact
     1141 ccagcctgtg gttccgcaga tggctggaac ctgcctggcg tggacctgca gagcagtagc
     1201 acccacccag catggggtca catggcccca gtactgctca caaccctgtc ctgtcccact
     1261 gcacaccatc cacacagatg acgctctgct ttcgctgctg atatggaacc aatagccaca
     1321 atttcttgta ccctggggaa agtatgattt gagcttaggt tcctgttgat tttgagaacg
     1381 tgaggaaaag agacaggctg tggtgacttg taccagtcat ccaagtacct tggaggtaga
     1441 agcaggagga gttaagagct acatagtgag ctcacacttg cctggtgtgc tacatgagat
     1501 cctgcttcaa aagaacaaaa ataaagtcag taaaagaaag aaatgtggag cagatggtat
     1561 ctgttgttca ttcaggatga ccttaattgt tataaagtag ttaataaaag acttaaaaca
     1621 tcc
//
