LOCUS       NM_053404               1406 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus dynactin subunit 4 (Dctn4), mRNA.
ACCESSION   NM_053404
VERSION     NM_053404.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   2  (bases 1 to 1406)
  AUTHORS   Lim,C.M., Cater,M.A., Mercer,J.F. and La Fontaine,S.
  TITLE     Copper-dependent interaction of dynactin subunit p62 with the N
            terminus of ATP7B but not ATP7A
  JOURNAL   J Biol Chem 281 (20), 14006-14014 (2006)
   PUBMED   16554302
REFERENCE   3  (bases 1 to 1406)
  AUTHORS   Schroer,T.A.
  TITLE     Dynactin
  JOURNAL   Annu Rev Cell Dev Biol 20, 759-779 (2004)
   PUBMED   15473859
  REMARK    Review article
REFERENCE   4  (bases 1 to 1406)
  AUTHORS   Garces,J.A., Clark,I.B., Meyer,D.I. and Vallee,R.B.
  TITLE     Interaction of the p62 subunit of dynactin with Arp1 and the
            cortical actin cytoskeleton
  JOURNAL   Curr Biol 9 (24), 1497-1500 (1999)
   PUBMED   10607597
REFERENCE   5  (bases 1 to 1406)
  AUTHORS   Eckley,D.M., Gill,S.R., Melkonian,K.A., Bingham,J.B., Goodson,H.V.,
            Heuser,J.E. and Schroer,T.A.
  TITLE     Analysis of dynactin subcomplexes reveals a novel actin-related
            protein associated with the arp1 minifilament pointed end
  JOURNAL   J Cell Biol 147 (2), 307-320 (1999)
   PUBMED   10525537
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF192494.1.
            
            [WARNING] On Aug 15, 2024 this sequence was replaced by
            NM_053404.3.
            
            On Jun 10, 2007 this sequence version replaced NM_053404.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF192494.1, AF190798.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132269, SAMD00132274
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..1406
                     /gene="Dctn4"
                     /note="dynactin subunit 4"
                     /db_xref="GeneID:84428"
                     /db_xref="RGD:71023"
     CDS             1..1404
                     /gene="Dctn4"
                     /note="dynactin subunit p62; dynactin 4 (p62)"
                     /codon_start=1
                     /product="dynactin subunit 4"
                     /protein_id="NP_445856.1"
                     /db_xref="GeneID:84428"
                     /db_xref="RGD:71023"
                     /translation="MASLLQSERVLYLVQGEKKVRAPLSQLYFCRYCSELRSLECVSH
                     EVDSHYCPSCLENMPSAEAKLKKNRCANCFDCPGCMHTLSTRATSISTQLPDDPAKTT
                     MKKAYYLACGFCRWTSRDVGMADKSVASGGWQEPENPHAQRMNKLIEYYQQLAQKEKV
                     ERDRKKLARRRNYMPLAFSQHTIHVVDKYSLGTRLQRPRAGASISTLAGLSLREGEDQ
                     KEVKIEPAQAVAEVEPLPEDYYTRPVNLTEVTTLQQRLLQPDLQPVSASQLYPRHKHL
                     LIKRSLRCRKCEHNLSKPEFNPTSIKFKIQLVAVNYIPEVRIMSIPNLRYMKESQVLL
                     TLTNPVENLTHVTLLECEEGDPDNINSTAKVVVPPKELILAGKDAAAEYDELAEPQDF
                     QDDPDIVAFRKANKVGIFIKVTPQREEGDVTVCFKMKHDFKNLAAPIRPMEESDQGTE
                     VIWLTQHVELSFGPLLP"
     exon            1..135
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            136..206
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            207..385
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            386..429
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            430..537
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            538..558
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            559..632
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            633..745
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            746..855
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            856..929
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            930..984
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1092
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1190
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..1406
                     /gene="Dctn4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcgtcct tgctgcagtc ggagcgggtt ctctatctcg tccaaggaga aaagaaggtt
       61 cgggccccgc tctcacagct ctacttctgc cgctactgca gtgagcttcg atcgctggaa
      121 tgtgtgtcac acgaggtgga ctctcattat tgtcccagct gcttagaaaa catgccatca
      181 gctgaagcca aattaaaaaa gaatagatgt gccaactgct ttgactgtcc tggatgcatg
      241 cacaccctct ccacccgagc tacaagcatc tccacacagc ttccagacga cccagccaaa
      301 accactatga agaaagccta ttacctggcc tgtggatttt gtcgatggac atctagagat
      361 gtgggcatgg cagacaaatc tgtagctagt ggtggttggc aagaaccaga aaatcctcat
      421 gcacaacgga tgaacaaatt gattgaatat taccagcagc ttgctcagaa ggaaaaggtt
      481 gaacgagatc gcaagaaact ggcacggcga agaaattaca tgcctttggc tttttcgcaa
      541 cacactattc atgtagtgga caagtacagc cttgggacca ggcttcagcg accacgagct
      601 ggtgcatcca ttagtacact tgccggactt tcccttagag aaggagaaga ccagaaggag
      661 gtaaagattg agccagctca ggccgtcgct gaagtggagc ctctgcctga agactattac
      721 acacgaccag tgaacctgac agaggtgacc acccttcagc agcgcctctt acagcctgac
      781 ctgcagcctg tctcagcctc gcagctttat cctcgacaca agcaccttct gatcaaacgg
      841 tccctgcgct gtcggaaatg tgaacacaat ttgagcaaac cagaatttaa tccaacatct
      901 atcaaattca aaatccagtt ggttgctgtc aattatattc cagaagtgag aatcatgtcg
      961 atccccaatc ttcgctacat gaaggaaagc caggtcctct tgactcttac aaatccagtg
     1021 gagaacctca cccatgtaac tctgctggag tgcgaagagg gggaccctga taacatcaac
     1081 agcactgcta aggtggtggt gcctcccaaa gagctcatct tagccggcaa ggatgcagca
     1141 gcagagtacg atgagctggc agagccccag gacttccagg atgaccctga cattgtagct
     1201 ttcagaaaag ccaacaaagt aggcatcttc atcaaagtca ccccacagcg tgaggaaggg
     1261 gacgtgaccg tgtgcttcaa gatgaaacat gattttaaaa acctggctgc ccccatccgc
     1321 cctatggaag aaagcgacca gggcacagaa gtcatttggc tcactcagca tgtggaactg
     1381 agctttggcc ctcttcttcc ttaaaa
//
