LOCUS       NM_001191831            5540 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus decapping mRNA 1A (Dcp1a), transcript variant 1,
            mRNA.
ACCESSION   NM_001191831 XM_341395
VERSION     NM_001191831.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5540)
  AUTHORS   Jefferson,M., Donaszi-Ivanov,A., Pollen,S., Dalmay,T., Saalbach,G.
            and Powell,P.P.
  TITLE     Host factors that interact with the pestivirus N-terminal protease,
            Npro, are components of the ribonucleoprotein complex
  JOURNAL   J Virol 88 (18), 10340-10353 (2014)
   PUBMED   24965446
REFERENCE   2  (bases 1 to 5540)
  AUTHORS   Oh,J.Y., Kwon,A., Jo,A., Kim,H., Goo,Y.S., Lee,J.A. and Kim,H.K.
  TITLE     Activity-dependent synaptic localization of processing bodies and
            their role in dendritic structural plasticity
  JOURNAL   J Cell Sci 126 (Pt 9), 2114-2123 (2013)
   PUBMED   23487039
REFERENCE   3  (bases 1 to 5540)
  AUTHORS   Li,Y., Chen,R., Zhou,Q., Xu,Z., Li,C., Wang,S., Mao,A., Zhang,X.,
            He,W. and Shu,H.B.
  TITLE     LSm14A is a processing body-associated sensor of viral nucleic
            acids that initiates cellular antiviral response in the early phase
            of viral infection
  JOURNAL   Proc Natl Acad Sci U S A 109 (29), 11770-11775 (2012)
   PUBMED   22745163
REFERENCE   4  (bases 1 to 5540)
  AUTHORS   Yamaji,M., Tanaka,T., Shigeta,M., Chuma,S., Saga,Y. and Saitou,M.
  TITLE     Functional reconstruction of NANOS3 expression in the germ cell
            lineage by a novel transgenic reporter reveals distinct subcellular
            localizations of NANOS3
  JOURNAL   Reproduction 139 (2), 381-393 (2010)
   PUBMED   19861488
REFERENCE   5  (bases 1 to 5540)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 5540)
  AUTHORS   Tritschler,F., Braun,J.E., Motz,C., Igreja,C., Haas,G.,
            Truffault,V., Izaurralde,E. and Weichenrieder,O.
  TITLE     DCP1 forms asymmetric trimers to assemble into active mRNA
            decapping complexes in metazoa
  JOURNAL   Proc Natl Acad Sci U S A 106 (51), 21591-21596 (2009)
   PUBMED   19966221
REFERENCE   7  (bases 1 to 5540)
  AUTHORS   Cougot,N., Bhattacharyya,S.N., Tapia-Arancibia,L., Bordonne,R.,
            Filipowicz,W., Bertrand,E. and Rage,F.
  TITLE     Dendrites of mammalian neurons contain specialized P-body-like
            structures that respond to neuronal activation
  JOURNAL   J Neurosci 28 (51), 13793-13804 (2008)
   PUBMED   19091970
REFERENCE   8  (bases 1 to 5540)
  AUTHORS   Zheng,D., Ezzeddine,N., Chen,C.Y., Zhu,W., He,X. and Shyu,A.B.
  TITLE     Deadenylation is prerequisite for P-body formation and mRNA decay
            in mammalian cells
  JOURNAL   J Cell Biol 182 (1), 89-101 (2008)
   PUBMED   18625844
REFERENCE   9  (bases 1 to 5540)
  AUTHORS   Fenger-Gron,M., Fillman,C., Norrild,B. and Lykke-Andersen,J.
  TITLE     Multiple processing body factors and the ARE binding protein TTP
            activate mRNA decapping
  JOURNAL   Mol Cell 20 (6), 905-915 (2005)
   PUBMED   16364915
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Sep 1, 2022 this sequence version replaced NM_001191831.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.167436.1,
                                           SRR26643298.70377.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-160               JAXUCZ010000016.1  5663437-5663596
            161-201             JAXUCZ010000016.1  5665669-5665709
            202-329             JAXUCZ010000016.1  5668060-5668187
            330-396             JAXUCZ010000016.1  5684670-5684736
            397-535             JAXUCZ010000016.1  5689264-5689402
            536-649             JAXUCZ010000016.1  5696175-5696288
            650-1408            JAXUCZ010000016.1  5700519-5701277
            1409-1474           JAXUCZ010000016.1  5702999-5703064
            1475-1690           JAXUCZ010000016.1  5704299-5704514
            1691-5540           JAXUCZ010000016.1  5704774-5708623
FEATURES             Location/Qualifiers
     source          1..5540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..5540
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /note="decapping mRNA 1A"
                     /db_xref="GeneID:361109"
                     /db_xref="RGD:1561298"
     exon            1..160
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1771
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /EC_number="3.6.1.62"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mRNA-decapping enzyme 1A; test2"
                     /codon_start=1
                     /product="mRNA-decapping enzyme 1A isoform 1"
                     /protein_id="NP_001178760.2"
                     /db_xref="GeneID:361109"
                     /db_xref="RGD:1561298"
                     /translation="MELLSRAEQEMSLAALKQHDPYITSIADLTGQVALYTFCPKANQ
                     WEKTDIEGTLFVYRRSASPYHGFTIVNRLNMHNLVEPVNKDLEFQLHEPFLLYRNASL
                     SIYSIWFYDKNDCHRIAKLMADVVEEEARRAQQAARDKQSPSQANGCSDQRPIDILEM
                     LSRAKDEYERNQMGGSNISSPGLQPSSQLSNLGSTETLEETPSGSQDKSAPSGHKHLT
                     VEELFGTSLPKEQPAPMGLESEDTDKLLGDAPQKEPSSFLPFPFEQSGGAPQAENLGV
                     HSVTHHTVQPEVSAPVLITPASIAQSGDKHPPSYTLPLSPVLSPTLPAEAPTTQVPHL
                     PRNSTMMQAVRTTPRQKSPLLNQPVPELSHSSLIASQSPFRAPVSLANTAGTAIPSSD
                     LLQKLRLTPQHDQIQAQPLGKGAMAPNFSSAAGQLATPESFIEPSSKTAAARAAVAAS
                     LSNMVLAPTLQSMQQNQDPEVFAQPKVLPSAIPIAGPPLVTATTTAVSSVLLSPSVFQ
                     QTVPRSADLERKASCPSPLTIGAENQRKPSIILSRSQLQDTLIHLIKNDSGFLSTLHE
                     VYLQVLTKSKDNHSL"
     exon            161..201
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            202..329
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            330..396
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            397..535
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            536..649
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            650..1408
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1474
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            1475..1690
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
     exon            1691..5540
                     /gene="Dcp1a"
                     /gene_synonym="RGD1561298"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggggctcg gcctggagat ccaagatgga gttgttgagt cgagctgagc aagagatgag
       61 tctggcggcc ttgaaacaac acgaccccta catcaccagc atcgcagacc tcacgggcca
      121 ggtcgccttg tacactttct gccccaaagc caaccagtgg gagaagactg atatagaagg
      181 gacattattt gtataccgaa ggtcagcttc gccttaccat ggctttacca ttgtcaaccg
      241 actgaacatg cacaatctgg ttgaaccagt gaataaagat ttggaatttc agctccatga
      301 accatttctt ctgtatagaa atgcaagttt gtcaatatac agcatctggt tctatgacaa
      361 gaatgactgt catcgcatag caaaacttat ggccgatgtg gtggaagagg aggcacgtcg
      421 agctcagcag gctgctcgag ataaacagag tcccagccag gccaacggct gcagtgacca
      481 gaggcccata gacatcctgg agatgctgag cagagccaag gatgagtatg agaggaatca
      541 gatgggcggc tcaaatatct ccagtccggg gctacagcca agctctcagc tctctaatct
      601 gggaagcacc gagactctag aagagacacc ctctggatca caagataagt ctgctccatc
      661 cggtcacaag catctgacgg tggaagaatt atttggaacc tccttgccaa aggagcagcc
      721 agcacctatg ggcctagagt cagaagacac ggacaagctg ctgggagatg caccacagaa
      781 agagcccagc tcattcctcc cgtttccctt tgagcagtca gggggagccc ctcaggctga
      841 aaacctgggt gtccattctg tcactcacca cacagtccag cctgaagtca gcgcccctgt
      901 gctgatcact cccgcctcca ttgcacagtc gggcgacaag catcccccaa gctacactct
      961 cccactgagc cctgtcctca gccccactct gccagctgaa gctcccacca cacaagttcc
     1021 ccacttacct cggaatagca ccatgatgca agcagtaagg accacaccta ggcagaaatc
     1081 tccactcctg aaccagcccg tccctgagct aagccacagc agtctgattg ctagccagag
     1141 ccccttcaga gccccagtga gcctggcaaa cacagctggc acggccatcc caagctctga
     1201 tctgctccag aaactcaggt tgaccccaca gcatgaccaa atacaggcac agccacttgg
     1261 aaaaggtgcg atggcaccca acttttcttc ggcagctggc cagctggcca cccctgagag
     1321 cttcatagag ccttcctcta agacagcagc agcaagagca gcagtcgcag cctccctgag
     1381 caacatggtg cttgctccaa ccctccagtc tatgcagcaa aaccaggatc ctgaagtatt
     1441 tgcccagcct aaggtgttac ccagtgccat cccgatcgca ggccctccat tggttactgc
     1501 aacaaccaca gcagtatctt cagtcctgct gtcccccagt gtgttccagc aaacagttcc
     1561 caggtctgca gacctagaaa ggaaagccag ctgcccctcc cccctcacta ttggagcaga
     1621 aaatcagagg aagccttcca ttattctcag caggtctcag ctccaggaca cactgataca
     1681 tctaataaag aatgactccg gctttctcag cacgcttcat gaagtttact tgcaggttct
     1741 gaccaagagc aaagacaacc acagcctatg actgcagtgg atgcagtgcg cagggacagg
     1801 gtccacctcc agacaagcag gcttcctcac gcacgtctga ggagaacatg gagcttcgag
     1861 gagcctgagg gcctcgtcct tagggatgtt tctagagacg ttctcagtga tgatggaggt
     1921 ttcactgtga agcatcacca gcaaaccttt gtttgacaaa aacagcaaga gaccattgtg
     1981 ttgagttccg tgggcgtttt catcagctgt aagcccgtgt gtggaatgag ggcctggctg
     2041 tcagctgctc tccaggcctg ggaggagcca ccagcctcag tgaagcccac gccctccctc
     2101 ctctacccct agaagctctg aactcaatgt cagctcgcag agtagcttca agatttaagg
     2161 atcaggattt aagtcgactc tttggaaggt atttgttcaa gtgaagtcta ttttctatga
     2221 gcacccgctt gggccttaag acttctggga tgtctttgtg ttccgggagg tgtccctggc
     2281 ctgccctgcc ctgcgcagac tccgtgaagc acagctcttt gggtggggcc cgcagggctc
     2341 tggtcggtgg agaggaggct tcacaccgtt gaagcagagg ccggggcaca cagatccaga
     2401 tcctaccaga aggctccatt ctagtgaact ctcagcagtt tagtgtcacg tttgtgcgtg
     2461 aagcgcagcc ttatttcctt ctccgtctaa acacagttga agttgttgtt gattgttttc
     2521 cttaactgct ggcaaaggac cagtggacca atctgacaaa gccattctgg ttccattcct
     2581 cagatgtgct gagagcagtt ttaaagctat gcagaaaagg gagctgtccc cacactgccc
     2641 ttccttcgtt gtagaatatg gagtcaagca agtgtgagac ccagacctca cagtgtgttc
     2701 ctaggctgcg ccctccggcc gcagtgcaga actgtagaaa tgctttgtga tgctgctatc
     2761 gatctgccat ggtttctatt tattctttta tggcatgtaa tggtgtttgg taatatttta
     2821 atgtagaatt tgattatttc agcaatagta attttgagat attctttgaa tgaaaagtgt
     2881 cttcgtttct atgatacagg tcattttcta gtatttaacc aattaagatg cactgcttac
     2941 ttttctgagc actatttaat gatgggtaag aaccctgttg gctcaaccag ctagcgtaag
     3001 gactcgctgt gaataatgct ggcaggcacg gtggtcccac cggacagttg cttaagcttt
     3061 aatgggaact caatcaaagg ctcatcgatt tctttctagc tgaagtttta gaaaattact
     3121 tattaattac ttactttggt cttagttttt tagcctaaag aacactttga ttggcttatg
     3181 ctgatctcaa catgcttcct ggacaatgtt tctgcttctc agttgagtgt cttctcttgt
     3241 ctacctagtt atgtgtgaag tgtgcagaat tcagggaagc ttagtctttt tcatactaag
     3301 ttagggatag tttcatgata gtatgtaaat atagcaacca aaaattaatt gttcacgtgt
     3361 catctaagca aggtcaagtt gtgatgaggt gatgaatgtt gctgacagta ggaggtggtg
     3421 gtcagggagc cgcagggctg ttctcgtaag gtgaacatgc acgcctgtag gcgtggtcac
     3481 cccgagtggt ctcagtggac atgagtaaac agatggttca aagcatcttc ttccagtagg
     3541 tgtgtgagtt tcgctgatgc tttcgagtgt atgtagtatt atatgagggc gaagcatggg
     3601 taccctaaag agtgcctgca gtcagaccgg atactttcac ccttaatccc aggaatgact
     3661 aagatgagca gaaggagaac ctctgagaag gaaggcttcc tcggtgtaga tggaaacttc
     3721 tgagtgccga agggatggag gcgggaggca ggtaaacctg tttcagctcc cagatttaca
     3781 tgctccaagc atttactcaa aagtcagagg ccagaagttc cagatcagga ctcctaggaa
     3841 gctgggcccg agtgagccca gagacccggg ccaagcctga ctgtaggtgc ggttggctga
     3901 gcctggccag agtccactcc gttgccttac tcctcgtcca ggcatgctgt ccagatgctc
     3961 tgctagctgg catagcttgc atgttaacag tgtcttccgg aaccttcgtt agactgagag
     4021 ggacattgga catgcttctc gctaagttgg cagagtccag aagacctcat taggccattt
     4081 ggtccatctg tgtacacacc cacccctgcc ccaggtgacc atagagtctg ggaagagtag
     4141 cccagagttc aacatgcagc aagcatgtct agggtgtcac tagtgagtga cactgctctt
     4201 tgttttgtac ttaatgttat gtctttgaat gggtggacac cccagctgac acccccaccc
     4261 cgacccccag tcctctcaga ctgccttgtt ccccgttgtt acctctccgg ggccccactt
     4321 gactttgcgt gctaagtctt acgtgaccat cagtatcagg aaaggcgttg tcccctgcag
     4381 gctccacacg aactgtcaca gctcgcctgg gcattggtgt tcattccaaa cccaagtcaa
     4441 ggccttagcc caggcttggc ttagatacca atgaccagca tgtgcaagca ttggttctgt
     4501 ctgtggcctg aatcttctat gggaattaat tataaatgcc attgaatcca ctagtaagta
     4561 atctttttaa accatgcagc tttattgctc tcttccccca aagaatgtcc tttgaaatgt
     4621 tctcagttca ggagtagagg ccgtaactgc ccttctaata ccaataatgc agcctgtgaa
     4681 actgacggtg cctaactgct cgtaaagcag agccagccat catatcacag ctcagaggga
     4741 agagaagggc acaggcgcgt gaggaggacc ctgcgagtca ggcactgagg gctcacggcc
     4801 caagcccgct gtcctcgggc acacctacta aggaccatgt gtttcttctg gcctgccttt
     4861 gttttccttc agttgtgttg agagtgtgca cactctggaa ctagcagtgc ccaccctgct
     4921 ttcaagaatc caaaatgcag ggtctgggca gagcacctca cagtgggctt tgaagctgct
     4981 caccaagagc atttcctgga ggaccagggc ctcaggagcc tgtggggtta ggtgtaaggt
     5041 tgttttgttg ttttattttt ttgtttttca tttcaagttt cagcaggaga gctgtgcaat
     5101 gtttccctcg gattccgatt tgacatcact ctttcaaaca ctgcaatgca atacatatca
     5161 ctttgaagtg ggagaaaatg caaagttgtg tttccctttt atctgtgaat ccttagagcg
     5221 tgttgttggt gtgcgtgcgg agtggtctca ctctctactg catcggccgt gtggctcccc
     5281 tggcttccct gcaccaggct ctcagccctt ccgaggacac gagaagccct gcgtgcgcca
     5341 ctgtgaagct ttcgttccgt gagcgcagtg ccacctcatt aaccttttta gtggtgtgga
     5401 ttttatacca tctgtgtatg tttgcaaata ttaagttatt acatgtttta aaatgagcat
     5461 ttttcatcct aaattttata tgtttgcaaa tatatttttt taataaaatt tcaaaaccaa
     5521 gttttagcac ctactaaaaa
//
