LOCUS       NM_001106201            3540 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus DNA cross-link repair 1A (Dclre1a), mRNA.
ACCESSION   NM_001106201 XM_001063735 XM_214730
VERSION     NM_001106201.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3540)
  AUTHORS   Sengerova B, Allerston CK, Abu M, Lee SY, Hartley J, Kiakos K,
            Schofield CJ, Hartley JA, Gileadi O and McHugh PJ.
  TITLE     Characterization of the human SNM1A and SNM1B/Apollo DNA repair
            exonucleases
  JOURNAL   J Biol Chem 287 (31), 26254-26267 (2012)
   PUBMED   22692201
REFERENCE   2  (bases 1 to 3540)
  AUTHORS   Dronkert ML, de Wit J, Boeve M, Vasconcelos ML, van Steeg H, Tan
            TL, Hoeijmakers JH and Kanaar R.
  TITLE     Disruption of mouse SNM1 causes increased sensitivity to the DNA
            interstrand cross-linking agent mitomycin C
  JOURNAL   Mol Cell Biol 20 (13), 4553-4561 (2000)
   PUBMED   10848582
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473986.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_214730.4, XM_001063735.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q55"
     gene            1..3540
                     /gene="Dclre1a"
                     /note="DNA cross-link repair 1A"
                     /db_xref="GeneID:292127"
                     /db_xref="RGD:1306156"
     exon            1..595
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             130..3210
                     /gene="Dclre1a"
                     /EC_number="3.5.2.6"
                     /codon_start=1
                     /product="DNA cross-link repair 1A protein"
                     /protein_id="NP_001099671.1"
                     /db_xref="GeneID:292127"
                     /db_xref="RGD:1306156"
                     /translation="MLEDAFWEEDIWEYKSKRKPKPVHPNSCSENISESVEKATDGKY
                     QSKGKGNKKRTSENPGETKDHPVCLAETNSQISAGSSQNSSCRDDIQQSQSKETTPKK
                     QCRTNRGKQATPKVRPLYDGHCPSCQMPFSSLLGQTPRWHVFECLDSPPISDTECPDG
                     VLCSSTIPSHYKKYTHVLLAQSRDSKEPLSPSQALAGRFAAAQPDSCNLEERRSVLLK
                     TEDSRKVLEDSLLMIQCLKTSQPPAETNRKSASSPRSQKSLVPQRAEFVKRDQLVGSG
                     SPLAEVAFNCQSESGSTGLPLPENGCGDFEISYSPLHSDEETYNCDQELDDSQQELFF
                     TQSSKDSSLEDVSATFENLHGPFPEEAEGIQPTAKTLAAQAGCSALSRGSTGNDSFQL
                     ISRTSGRLSGEDPSDTDAAFLLLSPAPSAVGGATPNCQTTKAKPEKFHSLASRHQQQK
                     TETSAAGSHTSLPLLLSAMSKPLEKEGGERLPLHPTQSQRRGLWSKGSGAPGANCACS
                     NTQRPSSAPLNKSLSTAPSSPKGSASQPSKKVMKQMDIGVFFGLPPKTQDTSPRERAS
                     EGPKASPVVSPSEKRPRLCKRKAQSSLSDLEFDAKNLNESQHSMELSGERAQHRRKRH
                     KKSNSPQEGTYQGRSGHLTNNPELGAVSLRRSKAFARRTPSRTQRGAVNISESSGGGE
                     SRRTCPFYKRIPGTGFTVDAFQYGEIEGCTAYFLTHFHSDHYAGLSKDFTRPIYCSEI
                     TGSLLKKKLRVQEQYIHQLPMDTECIVDGVKVVLLDANHCPGATMILFQLPNGAVTLH
                     TGDFRADPSMERSLLASRKVHTLFLDTTYCSPEYTFPSQQEAIQFAINTAFEAVTLNP
                     RALIVCGTYCIGKEKVFLAIADVLGSKVGMSQEKYKTLQCLNIPEVSSLITTDMCNSL
                     VHLLPMMQINFKGLQNHLKKCGGKFDQILAFRPTGWTHSNNITSIADITPQTKGNIAI
                     YGIPYSEHSSYLEMKRFVQWLKPQKIIPTVNVGTFQSRNTMEKYFKEWRLEAGY"
     exon            596..2212
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2213..2346
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2347..2465
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2606
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2607..2752
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2753..2907
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            2908..3049
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
     exon            3050..3540
                     /gene="Dclre1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagctttcag ttccaaccaa attagttgac ttttggttac tttttttttc ctattaaaat
       61 ttcattataa gaaatgcact gtgaattcac caaagactag tgccacgctc gtaaaaaatc
      121 atttttgcca tgttagaaga cgcgttttgg gaagaagaca tctgggaata taaatctaaa
      181 agaaaaccca aaccagtaca tccaaatagt tgttctgaaa atatttcaga atctgttgaa
      241 aaagcaacag atggaaaata ccagtccaaa ggaaaaggaa acaaaaagag aacttcagaa
      301 aatcctggcg agacaaagga ccatccagtg tgccttgcag aaacaaacag tcagatttct
      361 gcaggatcca gccagaattc aagctgtaga gacgacattc agcagtctca gagcaaagag
      421 acaacaccaa aaaagcaatg tagaacaaac agaggcaagc aggcgacccc aaaggtgcgc
      481 ccgctttatg atggacactg ccctagctgc cagatgccct tctcctcatt actaggtcag
      541 acaccccggt ggcatgtttt tgagtgtttg gattctccac ccatctcgga cacagagtgc
      601 cctgacggcg tgctgtgtag ctccacaatt ccttcccact ataagaaata cactcacgtc
      661 ctgcttgctc aaagtcgaga tagcaaggag cccctcagcc cctcgcaggc gttggctggg
      721 cgcttcgctg cagcacagcc agattcttgt aaccttgagg aaaggcggtc tgtgcttctg
      781 aaaactgagg actcaagaaa agtgttagaa gattctttgt tgatgataca gtgtctaaaa
      841 acatcccagc ctccagctga aaccaacagg aagagtgcct cttctccacg ttcccaaaag
      901 tcactggttc cacagcgtgc agagtttgtt aagagagacc agctggtggg aagcggatct
      961 ccccttgctg aggttgcctt caactgccaa agcgagtcag ggagtactgg tttgccattg
     1021 ccagaaaatg gctgcggcga cttcgagatc tcttactctc cgctgcacag tgacgaggag
     1081 acttacaact gcgaccaaga gctggacgac tcacagcagg agctgttttt cacccaaagc
     1141 tctaaagaca gcagcctaga agatgtctct gccacgttcg aaaaccttca tggtcccttc
     1201 ccagaggaag cagaggggat ccagcccaca gcgaagaccc tggccgctca ggctgggtgt
     1261 agtgcgctga gtagaggcag tacaggaaat gactctttcc agctcatctc ccgcacctcg
     1321 ggtcggcttt ccggagagga cccatcagat acagatgccg ccttcctctt gctttcacct
     1381 gcgccgtcgg cagtgggagg cgctactcct aattgccaga ccaccaaggc aaagccagaa
     1441 aaattccact cacttgcatc acgtcatcag caacagaaaa ctgaaacgtc ggccgccggc
     1501 agtcatacct cgctgccact acttctaagt gccatgtcaa agccacttga aaaggaggga
     1561 ggcgagcgtc tgcctttgca tccaacccaa agtcagagga gaggattatg gagtaagggc
     1621 tcgggtgctc caggcgctaa ctgtgcctgc tcgaacacac agaggccctc tagcgcgccc
     1681 cttaacaagt cattgagcac agcgccttcc agccccaagg gcagtgcaag ccaaccttct
     1741 aagaaagtaa tgaagcaaat ggacataggt gtgttttttg gactgccacc caaaacacaa
     1801 gacacatcac caagggaaag agcgtcagaa gggccaaagg ccagtccagt tgtgagtccc
     1861 agtgaaaaga ggccccggtt gtgcaagagg aaagcgcaga gctccctaag tgacttagaa
     1921 tttgatgcaa agaatttaaa tgagagccag cactctatgg aactgtctgg agagagggcc
     1981 caacatcgaa gaaagagaca taaaaagtcc aattcaccac aggaaggaac ataccaggga
     2041 aggtcaggtc acctcactaa caatccagag ttgggggcag tcagcttgag gagaagcaaa
     2101 gcctttgcaa gacggactcc cagcaggacg cagagagggg ccgtgaacat ttccgagtcc
     2161 tctggtggag gggaatcgag gagaacatgt ccgttctata agagaatccc cgggactggc
     2221 ttcaccgtgg atgcttttca gtatggcgag atcgaaggct gcactgccta cttccttaca
     2281 catttccact ctgatcatta tgctgggttg tcgaaggact tcacacggcc gatctattgt
     2341 agcgagatca ctggcagtct gttgaagaag aagcttcgtg tgcaggaaca atacatacat
     2401 cagttgccga tggacaccga atgtatagtg gacggtgtga aggttgtttt gctggatgcc
     2461 aatcactgtc caggtgctac catgatcctt ttccagcttc ctaacggtgc cgtcacactg
     2521 cacactggag acttccgagc agaccccagc atggaacgct ctctccttgc cagccgcaaa
     2581 gtccacacac tgttcctaga caccacatac tgcagcccag aatatacctt cccgtctcag
     2641 caggaggcta tccagtttgc catcaacact gcctttgagg ctgtaactct aaacccacgt
     2701 gcccttattg tctgtggcac gtactgtatc ggaaaggaga aagtcttcct agccattgcc
     2761 gatgttttag gttcaaaggt gggcatgtcc caggaaaaat ataaaactct gcagtgcctc
     2821 aatatacccg aagtcagctc cctcattacc acagacatgt gcaactctct ggttcacctc
     2881 ctccccatga tgcaaatcaa ttttaagggt ttgcagaacc acttgaagaa gtgtggtggg
     2941 aaatttgatc agattttggc tttccgacct acaggatgga cacactctaa caacataacg
     3001 agcatagcag atattactcc ccagacaaaa ggaaacatag caatatatgg aatcccctat
     3061 agtgagcaca gcagctactt agaaatgaag cgttttgtcc agtggctaaa gccacagaaa
     3121 atcataccca ccgtaaacgt cggcaccttt cagtccagga acacgatgga gaaatatttt
     3181 aaggagtgga gattggaagc cggatactga tgccgtcaca gacgtcagct gggctccata
     3241 cagcaggcat caataatgaa atccatgtgc agcacggtcc ctgagaacag tcgcagggtc
     3301 aagttcctca tttgctttga acagtgacgt acccaaggtg ctgggcacct ctcagagccc
     3361 ccagggacag ctgggagtag ctagtcccag tccctttcat tcttaatctc ttcccccata
     3421 gaagcaacag tcatctgcag caaacatgga caccagacac agagcattat ctatgtaatt
     3481 gtgaaataaa acttttatat aatatgtatt cctaaataaa atttaatata gaacttacca
//
