LOCUS       NM_130419               2836 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus discoidin, CUB and LCCL domain containing 2
            (Dcbld2), mRNA.
ACCESSION   NM_130419 XM_346417
VERSION     NM_130419.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2836)
  AUTHORS   Kobuke,K., Furukawa,Y., Sugai,M., Tanigaki,K., Ohashi,N.,
            Matsumori,A., Sasayama,S., Honjo,T. and Tashiro,K.
  TITLE     ESDN, a novel neuropilin-like membrane protein cloned from vascular
            cells with the longest secretory signal sequence among eukaryotes,
            is up-regulated after vascular injury
  JOURNAL   J Biol Chem 276 (36), 34105-34114 (2001)
   PUBMED   11447234
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Mar 10, 2021 this sequence version replaced NM_130419.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF387549.1, SRR26643289.30719.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-442               JAXUCZ010000011.1  55648644-55649085   c
            443-670             JAXUCZ010000011.1  55633091-55633318   c
            671-808             JAXUCZ010000011.1  55625680-55625817   c
            809-860             JAXUCZ010000011.1  55614029-55614080   c
            861-933             JAXUCZ010000011.1  55610936-55611008   c
            934-1067            JAXUCZ010000011.1  55610508-55610641   c
            1068-1108           JAXUCZ010000011.1  55609388-55609428   c
            1109-1324           JAXUCZ010000011.1  55608245-55608460   c
            1325-1449           JAXUCZ010000011.1  55607412-55607536   c
            1450-1600           JAXUCZ010000011.1  55603793-55603943   c
            1601-1681           JAXUCZ010000011.1  55602925-55603005   c
            1682-1807           JAXUCZ010000011.1  55602653-55602778   c
            1808-1901           JAXUCZ010000011.1  55598821-55598914   c
            1902-1951           JAXUCZ010000011.1  55596718-55596767   c
            1952-2089           JAXUCZ010000011.1  55595701-55595838   c
            2090-2836           JAXUCZ010000011.1  55594691-55595437   c
FEATURES             Location/Qualifiers
     source          1..2836
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     gene            1..2836
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /note="discoidin, CUB and LCCL domain containing 2"
                     /db_xref="GeneID:155696"
                     /db_xref="RGD:620543"
     exon            1..442
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     CDS             238..2556
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /note="discoidin, CUB and LCCL domain-containing protein
                     2; endothelial and smooth muscle cell-derived
                     neuropilin-like protein"
                     /codon_start=1
                     /product="discoidin, CUB and LCCL domain-containing
                     protein 2 precursor"
                     /protein_id="NP_569103.2"
                     /db_xref="GeneID:155696"
                     /db_xref="RGD:620543"
                     /translation="MASRAPLRAARSPQDPGGRAAPAATGRAPLPSAGWCPLPPGRNS
                     SSRPRLLLLLLLLLLLLPDAGAQKGDGCGHTVLGPESGTLTSINYPHTYPNSTVCKWE
                     IRVKTGERIRIKFGDFDIEDSDYCHLNYLKIFNGIGVSRTEIGKYCGLGLQMNQSIES
                     KGSEITVLFMSGIHASGRGFLASYSVIDKQDLITCLDTVSNFLEPEFSKYCPAGCLLP
                     FAEISGTIPHGYRDSSPLCMAGIHAGVVSDVLGGQISVVISKGTPYYESSLANNVTSM
                     VGYLSTSLFTFKTSGCYGTLGMESGVIADPQITASSVLEWTDHMGQENSWKPEKARLR
                     KPGPPWAAFATDEHQWLQIDLNKEKKITGIVTTGSTLIEHNYYVSAYRVLYSDDGQKW
                     TVYREPGAAQDKIFQGNKDYHKDVRNNFLPPIIARFIRVNPVQWQQKIAMKVELLGCQ
                     FTLKGRLPKLTQPPPPRNSNNLKNTTVHPKLGRAPKFTQALQPRSRNDLPLLPAQTTA
                     TPDVKNTTVTPSVTKDVALAAVLVPVLVMALTTLILILVCAWHWRNRKKKAEGTYDLP
                     HWDRAGWWKGVKQLLPAKSVEHEETPVRYSNSEVSHLSPREVTTVLQADSAEYAQPLV
                     GGIVGTLHQRSTFKPEEGKEASYADLDPYNAPVQEVYHAYAEPLPVTGPEYATPIVMD
                     MSGHSTASVGLPSTSTFRTAGNQPPALVGTYNTLLSRTDSCSSGQAQYDTPKGGKPAA
                     APEELVYQVPQSTQEASGAGRDEKFDAFKETL"
     exon            443..670
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            671..808
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            809..860
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            861..933
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            934..1067
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1108
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1324
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1449
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1450..1600
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1601..1681
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1682..1807
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1808..1901
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1902..1951
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            1952..2089
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
     exon            2090..2836
                     /gene="Dcbld2"
                     /gene_synonym="Esdn"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctacgagcg gggcgggagc gcgtctcagc tcgtccccgg tgctaccctc cggtcccccg
       61 tgctctggcc tggggtctcg ggacgggaag ctcggcgaag gaaagcgagt gtggggagca
      121 gggcggaggg gtcgaggcgc gctgcgctgc ctcctgctcc tcgccgggtg ctgcgggccc
      181 cgggcgcgcg gggctccgcg gcgcgcgcac tatgcgggcg gattgccggc cgccgggatg
      241 gcgagccggg cgccgctgag agccgcgcgc agcccgcagg atcccggagg ccgggccgcg
      301 cccgccgcca ccggccgggc cccgctgccc agcgccggct ggtgtcccct ccctcctggc
      361 cgcaactcct cctccaggcc tcggctgctc cttctactgc tcctactgct cctactgctc
      421 ccggacgctg gagcccagaa aggtgatgga tgtggacaca ctgtactagg ccctgagagt
      481 ggaaccctta catccatcaa ctacccacat acctatccta acagtactgt gtgtaaatgg
      541 gagattcgag taaagacggg agaaagaatt cgcatcaagt tcggtgactt tgacattgaa
      601 gattctgatt attgtcacct taattacctg aaaatcttta atggaattgg agtcagcaga
      661 acggaaatag gcaagtactg tggtctgggt ttacaaatga atcagtcaat tgagtccaaa
      721 ggcagtgaaa tcacagtgct gttcatgagt ggaatccatg cttctggtcg aggatttttg
      781 gcttcttact cagttataga taaacaagat ttaatcactt gtttggatac tgtatctaat
      841 tttttggaac ctgagttcag taagtactgc ccagctggct gtctgctgcc ttttgctgaa
      901 atatctggaa cgattcctca tggatataga gattcttcac cgctgtgtat ggctggaatc
      961 catgcaggag tagtgtcaga tgtgctgggt ggccaaatca gcgttgtgat tagcaaaggc
     1021 accccatatt acgaaagttc tttggccaac aatgtcactt ccatggtggg atacttatct
     1081 acgagtctgt ttacatttaa gacaagtggt tgctatggga ctctagggat ggagtcaggt
     1141 gtgatcgccg atccccagat aacagcatca tctgtactgg agtggactga ccacatgggg
     1201 caggagaaca gctggaaacc cgagaaggcc aggctgagaa aaccggggcc tccctgggct
     1261 gcttttgcca ctgatgagca tcagtggctg caaattgacc ttaataagga gaagaagata
     1321 acaggcatcg taaccactgg atctaccctg atagagcaca attactatgt gtctgcctac
     1381 agagttctgt acagtgacga tgggcagaaa tggactgtgt acagagagcc tggtgcggct
     1441 caggacaaga tatttcaagg aaacaaagat tatcacaagg atgttcgtaa taactttttg
     1501 ccaccaatta ttgcacgttt cattagagtg aaccctgtcc agtggcaaca gaaaattgcc
     1561 atgaaagtgg aattgctggg atgtcagttc actctgaaag gtcgccttcc aaagcttact
     1621 cagcctcccc cacctcggaa cagcaataac ctcaaaaaca ctacagttca tcccaaacta
     1681 ggtcgtgccc ctaaatttac tcaagcactc caaccacgaa gtaggaatga ccttcctctg
     1741 ctgccggccc agacaactgc cactcctgat gtcaaaaaca cgactgtgac tcccagtgtg
     1801 accaaagatg ttgcactggc cgccgttctg gttcctgtgc tggtcatggc cctcaccaca
     1861 ctcatcctca ttctagtgtg tgcttggcat tggagaaaca gaaagaaaaa agccgaaggc
     1921 acctatgatt taccccactg ggatcgggca ggctggtgga aaggagtgaa gcagcttctc
     1981 cctgccaaat cggtggaaca cgaggagacg ccagtgcgct acagcaacag tgaagttagt
     2041 cacctgagcc cgagggaagt cacgacagtg ctgcaagctg attctgcaga atacgcacag
     2101 cccctcgtgg gaggaattgt tggcacactc catcagagat ctacctttaa acctgaagaa
     2161 ggaaaagaag cgagctacgc agatctagac ccctacaacg ctccagtaca ggaagtgtat
     2221 catgcctacg ctgagccgct gccggtaacg gggcctgagt acgcaacccc aatcgtcatg
     2281 gacatgtcag ggcactccac agcctcagtt ggtctgccct ccacatccac tttcagaact
     2341 gcagggaacc agcctcccgc attagtggga acttacaaca ctcttctctc caggactgac
     2401 agctgttcct cgggccaggc tcagtacgac accccaaaag gtgggaagcc agcagctgcc
     2461 ccagaggaac tggtgtacca ggtgccgcag agcacccagg aagcatcagg agcaggaagg
     2521 gatgagaaat ttgatgcttt taaagaaacc ctttgacggt ggtgctgctt tttacaaagc
     2581 atccatttaa aagcacatgg ctttttaatt cttagtggta gtaatagtag aatgtattac
     2641 gtatctgtca ctaaagtggt taggggatgt ggtgaccgag gtacaagaaa ctacttgcct
     2701 tgccatcttg ctttaaaggt gttcctatgt ggcacagtta ctgcttgcct gttacatttg
     2761 aaacatcctg tttgttacta ctgtaaaaca ctatttttaa tacagaaaaa gctccctata
     2821 atgcacttca aagaaa
//
