LOCUS       NP_001009686             549 aa            linear   ROD 27-APR-2025
DEFINITION  DDB1- and CUL4-associated factor 11 [Rattus norvegicus].
ACCESSION   NP_001009686 XP_240183
VERSION     NP_001009686.1
DBSOURCE    REFSEQ: accession NM_001009686.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 549)
  AUTHORS   Jin,J., Arias,E.E., Chen,J., Harper,J.W. and Walter,J.C.
  TITLE     A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2,
            which is required for S phase destruction of the replication factor
            Cdt1
  JOURNAL   Mol Cell 23 (5), 709-721 (2006)
   PUBMED   16949367
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC091364.1.
            
            On Jan 13, 2005 this sequence version replaced XP_240183.2.
            
            Transcript Variant: This variant (1) is the protein-coding variant.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091364.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..549
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p13"
     Protein         1..549
                     /product="DDB1- and CUL4-associated factor 11"
                     /note="WD repeat-containing protein 23; WD repeat domain
                     23"
                     /calculated_mol_wt=61746
     Region          1..40
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Site            73
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q91VU6; propagated from
                     UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Site            75
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q91VU6; propagated from
                     UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          80..100
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          170..210
                     /region_name="WD 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          <180..511
                     /region_name="WD40"
                     /note="WD40 repeat [General function prediction only];
                     COG2319"
                     /db_xref="CDD:441893"
     Region          180..214
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          216..258
                     /region_name="WD 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          221..263
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          263..302
                     /region_name="WD 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          269..305
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          305..345
                     /region_name="WD 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          310..352
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          353..392
                     /region_name="WD 5"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          359..394
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          435..480
                     /region_name="WD 6"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          444..470
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          481..520
                     /region_name="WD 7"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5M9G8.1)"
     Region          486..510
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     CDS             1..549
                     /gene="Dcaf11"
                     /gene_synonym="Wdr23"
                     /coded_by="NM_001009686.2:261..1910"
                     /db_xref="GeneID:305895"
                     /db_xref="RGD:1311288"
ORIGIN      
        1 mgsrnsssag sgslepsegl srrgaglrrs eeeeeededv dlaqvlayll rrgqvrlvqg
       61 ggaanlqliq alsdseeehd sawdgrlgdr ynppvdatpd treleyneik trvelatgrl
      121 glgrtaqehs fprmlhqrer glchrgsfsl geqsrvmshf lpndlsftdt ysqkafcgiy
      181 skdgqifmsa cqdqtirlyd crygrfhkfk sikardvgws vldvaftpdg nhflysswsd
      241 yihicsiyge gdthtaldlr pderrfavfs iavssdgrev lggandgcly vfdreqnrrt
      301 lqiesheddv navafadiss qilfsggdda ickvwdrrtm reddpkpvga laghqdgitf
      361 idskgdaryl isnskdqtik lwdirrfssr egmeasrlaa tqqnwdyrwq qvpkkawkkl
      421 klpgdsslmt yrghgvlhtl ircrfspahs tgqqfiysgc stgkvvvydl lsghivkklt
      481 nhkacvrdvs whpfeekivs sswdgslrlw qyrqaeyfqd dmtesdrnrv cssgpapvpc
      541 psvafsspq
//
