LOCUS       NM_001109437            1942 bp    mRNA    linear   ROD 21-MAR-2023
DEFINITION  Rattus norvegicus debranching RNA lariats 1 (Dbr1), mRNA.
ACCESSION   NM_001109437 XM_001058421 XM_001058483
VERSION     NM_001109437.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1942)
  AUTHORS   Castello A, Fischer B, Eichelbaum K, Horos R, Beckmann BM, Strein
            C, Davey NE, Humphreys DT, Preiss T, Steinmetz LM, Krijgsveld J and
            Hentze MW.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 1942)
  AUTHORS   Kim JW, Kim HC, Kim GM, Yang JM, Boeke JD and Nam K.
  TITLE     Human RNA lariat debranching enzyme cDNA complements the phenotypes
            of Saccharomyces cerevisiae dbr1 and Schizosaccharomyces pombe dbr1
            mutants
  JOURNAL   Nucleic Acids Res 28 (18), 3666-3673 (2000)
   PUBMED   10982890
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC166797.1.
            
            On May 11, 2008 this sequence version replaced NM_001109437.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166797.1, SRR8487230.26513.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1942
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q31"
     gene            1..1942
                     /gene="Dbr1"
                     /note="debranching RNA lariats 1"
                     /db_xref="GeneID:681234"
                     /db_xref="RGD:1598038"
     exon            1..300
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..1741
                     /gene="Dbr1"
                     /note="debranching enzyme homolog 1"
                     /codon_start=1
                     /product="lariat debranching enzyme"
                     /protein_id="NP_001102907.1"
                     /db_xref="GeneID:681234"
                     /db_xref="RGD:1598038"
                     /translation="MRVAVAGCCHGELDKIYETLALAERRGPGPVDLLLCCGDFQAVR
                     NEADLRCMAVPPKYRHMQTFYRYYSGEKKAPVLTIFIGGNHEASNHLQELPYGGWVAP
                     NIYYLGLAGVVKYRGVRIGGISGIFKSHDYRKGHFECPPYNSSTIRSIYHVRNIEVYK
                     LKQLKQPVHIFLSHDWPRNIYHYGNKKQLLKTKSFFRQEVENSTLGSPAASELLEHLK
                     PAYWFSAHLHVKFAALMQHQATDKEQAGKETKFLALDKCLPHRDFLQVLEIEHDPSAP
                     EYLEYDVEWLAVLRATDDLMNVTGGLWNMPENNGLHTRWDYSATEEAMKDVMEKLNHD
                     PRIPCNFSMTAACYDPSKPQTQVQLVHRISPQTTKFCAQLGITDINVMIQKAKEEHHL
                     CGEYVQQGDLGTDDSEEDRSEYNTDTSALSSINPDEIMLDEEEEEEEAVSTHSDMNTP
                     SVEPSSDQASDLSTSFSDIRNLPSSMFVSSDDASRSPASEEGKSGETVECGDEKDLVE
                     FSVKRLSNEHEPEQRKRIKRRNQAIYAAVDDEDANDE"
     exon            301..425
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            426..506
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            507..592
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            593..817
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            818..898
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1044
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1928
                     /gene="Dbr1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggcgggata cgggcgggcg gcttgtccgc tcttctctgc tgttctgccc gggctgcagg
       61 tgctcgaggg cgttgcgttg gagttccgtg gcccaacgtc acgatgcggg tggctgtggc
      121 cggctgctgc cacggcgagc tggacaagat ctacgagact ctggcgctag cggagcggcg
      181 cggcccggga ccggtggatc tccttctgtg ctgtggcgac ttccaggcgg tgcgcaatga
      241 ggccgacctg cgctgcatgg ccgtgccgcc caaataccgc cacatgcaga ccttctaccg
      301 atactactct ggagagaaaa aggccccggt tctcaccatc ttcattggag gaaaccatga
      361 agcttcaaac catttgcaag agttacccta tggtggctgg gtggcgccaa atatttacta
      421 tttaggtttg gctggtgttg tcaaataccg aggagtaagg attggtggca tctctggcat
      481 atttaaatct catgactatc gaaaaggtca ttttgagtgt cccccttata attcgtctac
      541 cataaggagt atatatcatg tgagaaatat agaggtctac aaattaaaac agttaaagca
      601 gcctgtacat atattcttat ctcatgattg gccaagaaat atatatcatt atggaaataa
      661 gaagcaactt cttaagacca aatctttttt ccgccaagag gtggaaaata gcacactagg
      721 aagtcccgct gcctcggagc tgctagagca cctaaagccc gcatactggt tctcggcaca
      781 cctacacgtg aagtttgcgg ccttgatgca gcatcaggcc acagataaag aacaagcagg
      841 caaggaaacc aagtttttag ccttggacaa gtgcttgcca cacagagact ttcttcaggt
      901 gttagagata gaacatgacc ccagtgctcc tgagtactta gagtacgacg ttgaatggct
      961 tgctgtcctc agggccactg atgacctgat gaatgtgact gggggcctat ggaatatgcc
     1021 tgaaaacaat ggtctgcata caaggtggga ttatagtgca accgaagaag ccatgaaaga
     1081 cgtaatggag aaattgaacc atgaccccag aatcccctgt aacttcagca tgacagctgc
     1141 ttgttatgat cctagtaagc cacagacaca agtgcagctg gtgcacagga tcagtccgca
     1201 gactactaaa ttctgtgccc agcttggcat cacagacatt aacgtcatga ttcagaaggc
     1261 caaggaagag catcatctgt gtggtgaata tgtacagcag ggtgatctgg ggactgatga
     1321 ctctgaggag gaccggagtg aatacaacac agacacgtct gccctgtcct ccattaatcc
     1381 agatgaaata atgttggatg aggaagagga agaggaggaa gctgtaagta cccatagtga
     1441 catgaacacg ccttctgtgg aaccttcttc tgatcaagct tctgacctct ccacaagctt
     1501 ttctgacatc aggaacttac caagttccat gtttgtgtct tctgatgatg cctcccgttc
     1561 tccagctagt gaggagggga aatctggtga aactgtagag tgtggggatg aaaaagactt
     1621 ggttgagttt tcagtgaaga ggcttagtaa tgaacacgaa cctgaacaaa ggaagaggat
     1681 aaagaggagg aaccaggcca tctacgctgc agtggatgac gaggatgcca acgatgagta
     1741 ggacagagga cttgatgtgg taaatacaga tgtatgattt caagacccga tttttagcac
     1801 agaatttctg atttaatgac tggactttgt aataatgaaa tgatggaatt ttggttatat
     1861 gttctgtatt taggtgtatg tttatatgat tcagatatat acttattaaa atttcatatg
     1921 aaatttgaaa aaaaaaaaaa aa
//
