LOCUS       NM_001108568            3058 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus dual adaptor of phosphotyrosine and
            3-phosphoinositides 1 (Dapp1), mRNA.
ACCESSION   NM_001108568 XM_001078162 XM_342348
VERSION     NM_001108568.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3058)
  AUTHORS   Manna,D., Albanese,A., Park,W.S. and Cho,W.
  TITLE     Mechanistic basis of differential cellular responses of
            phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol
            3,4,5-trisphosphate-binding pleckstrin homology domains
  JOURNAL   J Biol Chem 282 (44), 32093-32105 (2007)
   PUBMED   17823121
REFERENCE   2  (bases 1 to 3058)
  AUTHORS   Dowler,S., Currie,R.A., Campbell,D.G., Deak,M., Kular,G.,
            Downes,C.P. and Alessi,D.R.
  TITLE     Identification of pleckstrin-homology-domain-containing proteins
            with novel phosphoinositide-binding specificities
  JOURNAL   Biochem J 351 (Pt 1), 19-31 (2000)
   PUBMED   11001876
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001108568.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.10989.1,
                                           SRR26643290.10171.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               JAXUCZ010000002.1  229148638-229148843 c
            207-329             JAXUCZ010000002.1  229133637-229133759 c
            330-463             JAXUCZ010000002.1  229129784-229129917 c
            464-594             JAXUCZ010000002.1  229118082-229118212 c
            595-642             JAXUCZ010000002.1  229109299-229109346 c
            643-705             JAXUCZ010000002.1  229107673-229107735 c
            706-791             JAXUCZ010000002.1  229106472-229106557 c
            792-879             JAXUCZ010000002.1  229104281-229104368 c
            880-3058            JAXUCZ010000002.1  229099319-229101497 c
FEATURES             Location/Qualifiers
     source          1..3058
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q43"
     gene            1..3058
                     /gene="Dapp1"
                     /note="dual adaptor of phosphotyrosine and
                     3-phosphoinositides 1"
                     /db_xref="GeneID:362046"
                     /db_xref="RGD:1310189"
     exon            1..206
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..945
                     /gene="Dapp1"
                     /note="dual adaptor for phosphotyrosine and
                     3-phosphoinositides 1"
                     /codon_start=1
                     /product="dual adapter for phosphotyrosine and
                     3-phosphotyrosine and 3-phosphoinositide"
                     /protein_id="NP_001102038.1"
                     /db_xref="GeneID:362046"
                     /db_xref="RGD:1310189"
                     /translation="MGRAELLGGNMSTQDPSELWGRADGGSDLFQDLGWYHSNLTRHA
                     AEALLLSNGRDGSYLLRDSNEQTGLYSLSVRAKDSVKHFHVEYTGYSFKFGFNEYSSL
                     KDFVKHFANQPLIGSETGTLIVLKHPYPRQVEEPSIYESVRVHTAMQTGRTENDLVPT
                     APSLGTKEGYLTKQGGLVKTWKTRWFTLQRNELKYFKDQMSPEPIRILDLTECSAVQF
                     DYSQDRVNCFCLVFPFRTFYLCAKTGVEADEWIKILRWKLSKIRKQLDQDDTIRSRSF
                     IFK"
     exon            207..329
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            330..463
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            464..594
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            595..642
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            643..705
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            706..791
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            792..879
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
     exon            880..3058
                     /gene="Dapp1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcctgtctt aagcgaggag gagcagcagc ggcagcagtg gatcccatct ctctctcttc
       61 actcagcacc tggaggggtg tcagccttca gaagcaagga cacgaatggg cagagcagaa
      121 cttctaggag ggaacatgag tacccaggat ccctcggagc tgtggggccg ggcagatgga
      181 ggctcagacc tgttccagga tttggggtgg taccatagca acctcacccg ccatgctgca
      241 gaggcccttc tgctctccaa cggacgcgat ggcagctacc tgctgaggga cagcaatgag
      301 cagaccgggc tctactctct ctccgtgaga gccaaagact ccgtcaaaca ctttcatgtt
      361 gaatacactg ggtactcctt taagtttggc tttaatgaat attcatctct aaaggatttc
      421 gtcaagcatt ttgcaaatca acctttgatt ggaagcgaga cagggactct gattgttctg
      481 aagcatccct atccaaggca agtggaggaa ccttccattt atgagtcagt ccgggtccac
      541 acggcgatgc agacgggaag aacagagaat gacctcgtgc ccactgcacc ttctctgggc
      601 accaaagaag gctatctcac caagcaggga ggtctggtaa agacttggaa aacgagatgg
      661 ttcactttgc aaaggaacga actgaaatat ttcaaagacc agatgtctcc agaaccaatt
      721 cggatcctag acctaacgga gtgctcagct gtccaatttg attactcgca ggatcgcgta
      781 aactgtttct gcttagtgtt cccattcagg acattttatc tctgtgcaaa gacgggagtc
      841 gaagccgatg aatggatcaa aatactgcga tggaagttgt caaaaataag aaaacagctg
      901 gatcaagacg acaccatccg atctcggtca tttatcttca aatagaactt tcttgctcaa
      961 gggcaaggtt gatgtgccag gtgtcggatc tgtggcggac ttcagaggaa agctcactga
     1021 agtatttcct ctaaaaacaa accaaaagca gatcctggtt ggaagctgta tgctgtttgc
     1081 tgattcatgg aaaacagctg gcaggacctg gctgtctgct cgggaacaca gatgcagtgc
     1141 cctgctgatg gcaactgcct aacatccatg tggagccact cttggacaca gcaccagctc
     1201 ggtggctgtc ccagtggctt aggcttgttg actttatttg cctggagtcc agccccaagt
     1261 catggatagc acaactaaac ttcaggacat gctccaagca gcaaggaaac agcagtgcat
     1321 caggaagttc gggctgtgct tttaggaagc agattaagat aataaacacc gaggacgttc
     1381 aaaggacagg ttgcttttct tttgtttata tacaaaaacc tcaaataggg ctgaagaggt
     1441 ggctcagcca tgaaaagtac agctgctctt gcagagaacc tgaattcagt ttccgggacc
     1501 tatatccagg ggttcacaaa tgcccaactc cagggaccca tgctcaagtg cgcgcatgca
     1561 cgcgcgctcg cgcacacaca cacacacaca cacacacaca cacacacaca cacacagtct
     1621 ttttaaaagg cttagaaggc tggagagatg gcttggtaag ccattttagc atactctgtg
     1681 ggatccttga gtgggttccc ccaaactcac acaaagatag gaggagagaa tcaattccac
     1741 aaaattgttc tctgacctct acatgtaaat gccagcatga atggccccac ctcccccccc
     1801 acacacacac acaaatccag tggacccttc acttctaatg ataaattgaa aactacatgt
     1861 tgtgtgggtg gatagatagg aaaaagtaaa tgaacgtgta ataaagggta ggaatgtttt
     1921 aaacagtaac accctgagaa gggtggtagt gaatcactta gtttaatggt tatcattaca
     1981 aatatatgta taagcactaa ttaaaactct ttagctgtca tttcttcaaa ttcatctaga
     2041 cttctccata aagcctgtgc tctgtctctt ttccgagctg tatgagatta tggccatgga
     2101 gtacccaaac gttaaaaggc gacttctgtt tcctagggag taaattaaat ctttgtaaaa
     2161 tccatggtac atagctgttg cagactagaa gaccaggact gagttgcaat gacttgctgg
     2221 tgttcagagg tcatgaacag atttttaatt tccaatcatt attgatctgg cttttttttt
     2281 ttaaagaagg gactcaaatg agtggtgagc cagcaagtga tgcagagctg acggaactct
     2341 gttcttgcag tagaaaggga caatagtttt cacttttgtc agtgtgacca agatgctgaa
     2401 gtggaatctg ctccccttca tccgtctcaa tgcttgagcc aacaatttac agaacgattc
     2461 actttcctct gtggttctaa gatgtttctg ccccctgtgc tgggtagggt gtgggatagc
     2521 tgctcatatc agagcaggcg ggaagcagaa caaggcagtc agtcacaggg aagggagagg
     2581 gcaagacagc gtcctcagaa atatgtctcg agtgtcatgc ttccacattc taccccctcc
     2641 tcatagtccg ctcagattct gatccaggaa tggattaaac catctatcgg gtcagcacac
     2701 acatctctgg cccaccttca gggacacatc cagaaatgta cgctcctcct tttggtattt
     2761 ctcaagttgg tgtcaagatt cattcataga accttgttaa gtatctttcc ctggtgtcta
     2821 aacacttaag aaaagtcgtt tatttcagag tttttagagc tgggttatgg atcaattaga
     2881 acaactggcc tcaatggggg ggggggtttg taacttgtta tgtttgtatt agatggaatg
     2941 agataaaata cattgtgtca aggagtaaga aatggctctg tactaaacac tctaccttct
     3001 gtaaaataca tttatttatg tttgttctgt tcattaaata atgtatgatt ttttgtat
//
