LOCUS       NM_022526               1591 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus death-associated protein (Dap), mRNA.
ACCESSION   NM_022526
VERSION     NM_022526.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1591)
  AUTHORS   Koren,I., Reem,E. and Kimchi,A.
  TITLE     DAP1, a novel substrate of mTOR, negatively regulates autophagy
  JOURNAL   Curr Biol 20 (12), 1093-1098 (2010)
   PUBMED   20537536
REFERENCE   2  (bases 1 to 1591)
  AUTHORS   Feinstein,E., Druck,T., Kastury,K., Berissi,H., Goodart,S.A.,
            Overhauser,J., Kimchi,A. and Huebner,K.
  TITLE     Assignment of DAP1 and DAPK--genes that positively mediate
            programmed cell death triggered by IFN-gamma--to chromosome regions
            5p12.2 and 9q34.1, respectively
  JOURNAL   Genomics 29 (1), 305-307 (1995)
   PUBMED   8530096
REFERENCE   3  (bases 1 to 1591)
  AUTHORS   Deiss,L.P., Feinstein,E., Berissi,H., Cohen,O. and Kimchi,A.
  TITLE     Identification of a novel serine/threonine kinase and a novel 15-kD
            protein as potential mediators of the gamma interferon-induced cell
            death
  JOURNAL   Genes Dev 9 (1), 15-30 (1995)
   PUBMED   7828849
REFERENCE   4  (bases 1 to 1591)
  AUTHORS   Shah,A.
  TITLE     Tuberculous pleural effusion: a diagnostic problem
  JOURNAL   Indian J Chest Dis Allied Sci 34 (3), 115-116 (1992)
   PUBMED   1302217
REFERENCE   5  (bases 1 to 1591)
  AUTHORS   Belokrylov,G.A. and Zhitnukhin,Iu.L.
  TITLE     [Effect of antibodies to rat and human cerebral cortex and white
            matter on heterologous T- and B-cells]
  JOURNAL   Zh Mikrobiol Epidemiol Immunobiol (9), 66-70 (1976)
   PUBMED   1087798
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1, BC060569.1 and FM053394.1.
            
            On Aug 1, 2012 this sequence version replaced NM_022526.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U05334.1, FQ228865.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-186               JAXUCZ010000002.1  83910113-83910298
            187-882             BC060569.1         5-700
            883-1181            FM053394.1         215-513
            1182-1591           JAXUCZ010000002.1  83962264-83962673
FEATURES             Location/Qualifiers
     source          1..1591
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..1591
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /note="death-associated protein"
                     /db_xref="GeneID:64322"
                     /db_xref="RGD:620641"
     exon            1..247
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..501
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /note="DAP-1"
                     /codon_start=1
                     /product="death-associated protein 1"
                     /protein_id="NP_071971.1"
                     /db_xref="GeneID:64322"
                     /db_xref="RGD:620641"
                     /translation="MSSPPEGKLETKAGHPPAVKVAGIRIVQKHPHTGDGKEKKDKDD
                     QEWESTSPPKPTVYISGVIARGDKDFPPAAAQVAHQKPHASMDKHVSPRTQHIQQPRK
                     "
     exon            248..344
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /inference="alignment:Splign:2.1.0"
     exon            345..387
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /inference="alignment:Splign:2.1.0"
     exon            388..1591
                     /gene="Dap"
                     /gene_synonym="Rap7a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caaggcgagg cggccggcaa agctcaggtg ggcggggccg tgccacgcag cgctccggag
       61 ccacgccccc gtccctgggc ggcagtgcgc gttcccgagc ggcgcgcgcc tcccgtcttt
      121 cctcccgagg ccttgcgcgc gcactgctgc ccacccgcgg ctgccatcgc ccctcagaaa
      181 accagcggcg ccatgtcttc gcctccagaa ggaaagctag agaccaaagc tggacatccg
      241 cccgccgtga aagtcgctgg gattcggatt gtgcagaaac acccacacac tggagatggg
      301 aaggaaaaga aagacaagga tgaccaagaa tgggaaagca ccagccctcc taaaccaaca
      361 gtgtacatct ctggtgttat tgcccggggt gacaaagact tccccccagc agctgcacaa
      421 gtggcccacc agaagccaca tgcctccatg gacaaacatg tttctccaag aacgcagcat
      481 atccaacagc ctcgcaagtg accaacgccc agacccctgc cacctcagca gcagcagcag
      541 cagcagcacc tgtgccccct ccaggatgct tccccgacaa aatcaactca aacaccttct
      601 acagagttta ctaaatttag aaatctaaga caaagcaaag tgggcctcgg ttgtgtcaga
      661 tccccatgtt taaaactaga agaggctcaa acaccaaatt ttgtttctaa gagtcctagt
      721 cgagtgtcag taaagggtca ttgaacccct agaagtgcca ttagcagaac atggcaagtc
      781 ctgagtaaaa ggaagtcctt cgcactatag cagtagttta aagtccttac tcgtggtcct
      841 aagaggaaga ggccactttg gagaggtttg ataaggttag gagaagaaaa aacaaaacac
      901 tatggtatgg tccgaacagc tgtgctccct tctgccccca gtccatggct gcaaatccct
      961 gtttttcaga aaagtcaaag agctagatgt agagccttct ggagtgctgc tcttggaggg
     1021 tcctcctggc tgtcccagtg gcctacagtg gctccagctc agttcacggt tgctctatga
     1081 gcaccatgta cgccaccagc ctttccagga ctactacatg gcctgtacca tgtcgctaaa
     1141 ggagggatgg gctcctcgga ttttatgagc aatccagtat cccaacagtg gccttcacat
     1201 ggagcagaac acagccccca agactgtgtt gtcagtctct tctttgtaat tactaaaatg
     1261 gtgggaaccc agggtcgctt tggagaccca gacttggctg cagcctacag ccttgctcag
     1321 tcatatggaa ccaaatctag gaagggacct tagagacagc aacgccagtt ccctgtgcag
     1381 accttcccac gtgttgcctg catccgcaat cccttttagt tcagccacct gaggggctac
     1441 cccgtgttcc gtgtactctg agctagctcc ggtgtgtgtc tgtggactct gggtcactaa
     1501 aggtttgccc gaatgaattt ctgaatcttt ggcgttgaga agatgttgat tctaataaag
     1561 ctcctgcatt tctgcctcag tgtctctctt a
//
