LOCUS       NM_138710               6459 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus DAB2 interacting protein (Dab2ip), mRNA.
ACCESSION   NM_138710
VERSION     NM_138710.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6459)
  AUTHORS   Ni,Q.F., Zhang,Y., Yu,J.W., Hua,R.H., Wang,Q.H. and Zhu,J.W.
  TITLE     miR-92b promotes gastric cancer growth by activating the
            DAB2IP-mediated PI3K/AKT signalling pathway
  JOURNAL   Cell Prolif 53 (1), e12630 (2020)
   PUBMED   31713929
REFERENCE   2  (bases 1 to 6459)
  AUTHORS   Li,Z., Li,L., Zhang,H., Zhou,H.J., Ji,W. and Min,W.
  TITLE     Short AIP1 (ASK1-Interacting Protein-1) Isoform Localizes to the
            Mitochondria and Promotes Vascular Dysfunction
  JOURNAL   Arterioscler Thromb Vasc Biol 40 (1), 112-127 (2020)
   PUBMED   31619063
REFERENCE   3  (bases 1 to 6459)
  AUTHORS   Chen,C., Geng,Q., Sun,D., Hu,W., Zhong,C., Fan,L. and Song,X.
  TITLE     Low Expression of ASK1-Interacting Protein-1 Is Significantly
            Correlated with Tumor Angiogenesis and Poor Survival in Patients
            with Early Stage Non-Small Cell Lung Cancer
  JOURNAL   Onco Targets Ther 12, 10739-10747 (2019)
   PUBMED   31849482
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6459)
  AUTHORS   Chen,S., Wang,L., Yao,B., Liu,Q. and Guo,C.
  TITLE     miR-1307-3p promotes tumor growth and metastasis of hepatocellular
            carcinoma by repressing DAB2 interacting protein
  JOURNAL   Biomed Pharmacother 117, 109055 (2019)
   PUBMED   31176165
REFERENCE   5  (bases 1 to 6459)
  AUTHORS   Xiao,Y., Li,Z.H. and Bi,Y.H.
  TITLE     MicroRNA-889 promotes cell proliferation in colorectal cancer by
            targeting DAB2IP
  JOURNAL   Eur Rev Med Pharmacol Sci 23 (8), 3326-3334 (2019)
   PUBMED   31081086
REFERENCE   6  (bases 1 to 6459)
  AUTHORS   Luo,D., He,Y., Zhang,H., Yu,L., Chen,H., Xu,Z., Tang,S., Urano,F.
            and Min,W.
  TITLE     AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum
            stress response
  JOURNAL   J Biol Chem 283 (18), 11905-11912 (2008)
   PUBMED   18281285
REFERENCE   7  (bases 1 to 6459)
  AUTHORS   Zhang,H., Zhang,H., Lin,Y., Li,J., Pober,J.S. and Min,W.
  TITLE     RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is
            critical for tumor necrosis factor-induced ASK1-JNK/p38 activation
  JOURNAL   J Biol Chem 282 (20), 14788-14796 (2007)
   PUBMED   17389591
  REMARK    Erratum:[J Biol Chem. 2007 Sep 14;282(37):27556. Zhang, Rong
            [corrected to Zhang, Haifeng]]
REFERENCE   8  (bases 1 to 6459)
  AUTHORS   Zhang,H., Zhang,R., Luo,Y., D'Alessio,A., Pober,J.S. and Min,W.
  TITLE     AIP1/DAB2IP, a novel member of the Ras-GAP family, transduces
            TRAF2-induced ASK1-JNK activation
  JOURNAL   J Biol Chem 279 (43), 44955-44965 (2004)
   PUBMED   15310755
REFERENCE   9  (bases 1 to 6459)
  AUTHORS   Zhang,R., He,X., Liu,W., Lu,M., Hsieh,J.T. and Min,W.
  TITLE     AIP1 mediates TNF-alpha-induced ASK1 activation by facilitating
            dissociation of ASK1 from its inhibitor 14-3-3
  JOURNAL   J Clin Invest 111 (12), 1933-1943 (2003)
   PUBMED   12813029
REFERENCE   10 (bases 1 to 6459)
  AUTHORS   Wang,Z., Tseng,C.P., Pong,R.C., Chen,H., McConnell,J.D., Navone,N.
            and Hsieh,J.T.
  TITLE     The mechanism of growth-inhibitory effect of DOC-2/DAB2 in prostate
            cancer. Characterization of a novel GTPase-activating protein
            associated with N-terminal domain of DOC-2/DAB2
  JOURNAL   J Biol Chem 277 (15), 12622-12631 (2002)
   PUBMED   11812785
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 27, 2020 this sequence version replaced NM_138710.3.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.13708.1,
                                           SRR26643296.8562.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-287               JAXUCZ010000003.1  39312745-39313031
            288-391             JAXUCZ010000003.1  39396549-39396652
            392-525             JAXUCZ010000003.1  39414184-39414317
            526-679             JAXUCZ010000003.1  39460589-39460742
            680-778             JAXUCZ010000003.1  39461711-39461809
            779-1333            JAXUCZ010000003.1  39462629-39463183
            1334-1478           JAXUCZ010000003.1  39465673-39465817
            1479-1623           JAXUCZ010000003.1  39465909-39466053
            1624-1860           JAXUCZ010000003.1  39468041-39468277
            1861-2062           JAXUCZ010000003.1  39469849-39470050
            2063-2241           JAXUCZ010000003.1  39471574-39471752
            2242-3130           JAXUCZ010000003.1  39472716-39473604
            3131-3283           JAXUCZ010000003.1  39474255-39474407
            3284-3477           JAXUCZ010000003.1  39476082-39476275
            3478-3565           JAXUCZ010000003.1  39480260-39480347
            3566-6459           JAXUCZ010000003.1  39480837-39483730
FEATURES             Location/Qualifiers
     source          1..6459
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3p11"
     gene            1..6459
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /note="DAB2 interacting protein"
                     /db_xref="GeneID:192126"
                     /db_xref="RGD:621686"
     exon            1..287
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     CDS             248..3733
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /note="ASK-interacting protein 1; DOC-2/DAB2 interactive
                     protein; DOC2/DAB2 interactive protein"
                     /codon_start=1
                     /product="disabled homolog 2-interacting protein"
                     /protein_id="NP_619724.3"
                     /db_xref="GeneID:192126"
                     /db_xref="RGD:621686"
                     /translation="MEPDSLLDPGDSYESPQERPGSRRSLPGSLSEKSPSMEPSAATP
                     FRVTGFLSRRLKGSIKRTKSQPKLDRNHSFRHILPGFRSAATAAADNERSHLMPRLKE
                     SRSHESLLSPSSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVTTSSGSKCFSCRSAA
                     ERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTT
                     GKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGR
                     QFVEKWYPVVTPNPKGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAA
                     LEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATK
                     AIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSAADLPEHQGNLKMCCELA
                     FCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLF
                     NLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLE
                     ISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQSIVSKLGPLPRILRDVHTA
                     LSTPGSGQLPGTNDLASTPGSGSSSVSAGLQKMVIENDLSGLIDFTRLPSPTPENKDL
                     FFVTRSSGVQPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPE
                     ALPADGQVPATQLVAGWPARAAPVSLAGLATVRRAVPTPTTPGTSEGAPGRPQLLAPL
                     SFQNPVYQMAAGLPLSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELAR
                     RPGELARRQMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPTMLST
                     LQYPRPSSGTLASASPDWAGPGTRLRQQSSSSKGDSPELKPRALHKQGPSPVSPNALD
                     RTAAWLLTMNAQLLEDEGLGPDPPHRDRLRSKEELSQAEKDLAVLQDKLRISTKKLEE
                     YETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDVQMKGIISRLMSVEEELKKD
                     HAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMRARNGVSPTNPTK
                     LQITENGEFRNSSNC"
     exon            288..391
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            392..525
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            526..679
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            680..778
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            779..1333
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            1334..1478
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            1479..1623
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            1624..1860
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2062
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            2063..2241
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            2242..3130
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            3131..3283
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            3284..3477
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            3478..3565
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
     exon            3566..6459
                     /gene="Dab2ip"
                     /gene_synonym="AIP-1; DIP1/2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tttagacatc tcgccgcctc ggtcccttct aatgtttcca ggcaggctgc ggggggagga
       61 aaaaaaggtt actgctactt taaatgtact gtatgaaggc gagggctgga aaggggcctg
      121 cttgcaggaa tacccagtca tctagttgga gaagccgcca gatggaatac aaaagaagcg
      181 caggcgctca tggagacggc ctcggttcat aaatcaggtg gggccacggc ccaggggccc
      241 acacgccatg gagcccgact ccctcctgga cccaggcgac tcctacgagt caccccaaga
      301 aaggccgggc tcccggcgca gccttcccgg cagcctgtca gagaaaagcc ccagcatgga
      361 gccctcggct gcaaccccgt tccgggtcac gggcttcctc agccgccgcc tcaagggctc
      421 catcaagcgc accaagagcc agcccaaact ggaccgcaac cacagcttcc gccacatcct
      481 gccggggttc cggagcgcag ccaccgccgc cgcggacaat gagaggtccc atctgatgcc
      541 aaggctgaag gaatctcgat cacacgagtc cctgctcagc cccagcagcg cagtggaggc
      601 cctggacctc agcatggagg aggaggtgct tatcaagcct gttcacagca gcatcctggg
      661 tcaggactac tgcttcgagg taacaacatc atcaggaagc aagtgtttct cctgccggtc
      721 agccgctgaa cgagataagt ggatggagaa cctgaggcga gcagtgcacc ccaacaagga
      781 caacagccgg cgtgtggagc acatcctgaa gctatgggtg attgaggcca aggatctgcc
      841 agccaagaag aagtatctgt gtgaactgtg cctggacgat gtactgtatg cccgtaccac
      901 gggcaagctc aagacggaca atgtcttctg gggagagcac ttcgagttcc acaacctgcc
      961 gcccctgcgc acagtcactg tccacctgta ccgggaaact gacaagaaga agaaaaagga
     1021 acgcaacagc tacctgggcc tggtgagcct gcctgccgcc tcggtggctg ggcggcagtt
     1081 tgtggagaag tggtacccag tggtgacacc taatcccaag ggtggcaaag gccctgggcc
     1141 catgatccga atcaaggcac gctaccagac catcaccatc ttgcctatgg agatgtacaa
     1201 ggagtttgct gagcacatca ctaaccacta cctggggctg tgtgcagccc ttgagcccat
     1261 cctcagtgcc aagaccaagg aggagatggc gtcggctctg gtgcacatcc tgcagagcac
     1321 aggcaaggtg aaggactttc taacagacct gatgatgtca gaggtggacc gctgtgggga
     1381 caatgagcac ctcatcttcc gggagaacac attggccacc aaggccatcg aagaatacct
     1441 caaactcgtg ggccagaagt acctgcagga cgcactaggt gagttcatca aagccctgta
     1501 tgagtcagac gaaaattgtg aagtggaccc cagtaagtgc tcagccgccg acctccccga
     1561 gcaccagggc aacctcaaga tgtgttgtga gctggccttc tgcaagatca tcaactccta
     1621 ctgtgtcttc cctcgggaac ttaaagaggt gttcgcctca tggcggcagg agtgtagcag
     1681 ccgcggccgg cctgatatca gtgaacgact cattagcgcc tccctcttcc ttcgcttcct
     1741 gtgccctgcc atcatgtcgc cctcgctctt caacctgctt caggagtatc ctgacgaccg
     1801 cacagctcgc accctcacgc tcatcgccaa agttacccag aacctggcca actttgccaa
     1861 gtttggcagc aaagaggaat acatgtcatt catgaaccag ttcctggagc acgagtggac
     1921 caacatgcag cgcttcctgt tggagatctc caaccctgag accctttcta acacagcagg
     1981 cttcgagggc tacatagacc tgggccggga gctctctagc ttacactctc tgctctggga
     2041 agctgtcagc cagcttgatc agagcattgt atccaagctg ggacccctgc ctcgtatcct
     2101 gagggatgtc cacacagcac tgagcactcc aggcagtggg cagctccctg gcaccaatga
     2161 cctggcctcc acaccaggct ctggcagcag cagtgtctca gctgggcttc agaagatggt
     2221 gattgagaat gatctctctg gtctgataga tttcacccgg ttaccgtctc caacccccga
     2281 aaacaaggac ttgttttttg tcacaaggtc ctccggggtc cagccttcac ctgcccgcag
     2341 ctcaagctac tcagaagcca acgagcctga cctgcagatg gccaacggca gcaagagcct
     2401 gtccatggtg gacctccagg acgcccgcac actggatggg gaggcaggtt ccccagtggg
     2461 ccccgaagcc ctccctgctg acgggcaggt acctgcaact cagctggtgg ctgggtggcc
     2521 agcccgggca gccccagtga gcctggcagg attggccaca gtgcggcggg cagtgccaac
     2581 accaaccaca ccaggcacct ccgagggtgc accaggccgg cctcagttgt tggcccctct
     2641 ctccttccag aatcccgtgt accagatggc tgctggcctg ccactgtcac cccgtggcct
     2701 tggtgactca ggctctgagg gccacagctc cctgagctct cacagcaata gtgaagagct
     2761 ggcagccgct gccaaactag gaagttttag cactgctgct gaggagctgg cacggcggcc
     2821 tggtgagctg gcacggaggc agatgtcact gactgagaag ggtggtcagc caacagtgcc
     2881 gaggcaaaat agtgcaggtc cccagcggag gattgaccag cctccaccgc cgccaccgcc
     2941 accacctcct gccccccggg gcaggacacc tcctaccatg ctgagcaccc tacaataccc
     3001 acgaccctca agtggaaccc tggcatcagc atcacctgac tgggctggcc ctggcacccg
     3061 gctgcggcaa cagtcctcct cttccaaggg agacagccca gagctgaagc cccgcgcctt
     3121 gcataagcag ggcccttcgc ccgtcagtcc caatgccctg gaccgcacgg ccgcttggct
     3181 cttgaccatg aacgcgcagt tgttagaaga cgagggtctg ggcccagatc ccccccacag
     3241 ggataggcta aggagtaagg aggagctcag ccaagcagaa aaggatctgg cggtgctgca
     3301 agacaagctg cggatctcca ccaagaagct ggaggagtac gagaccctgt tcaagtgcca
     3361 ggaggagacg acgcagaagc tggtgctcga gtaccaggct cggctggagg agggcgagga
     3421 gcggctgcgg cggcagcagg aagacaagga cgtccagatg aagggcatca tcagcaggtt
     3481 gatgtctgtg gaggaggaac tgaagaagga tcacgctgag atgcaagcgg ccgtagactc
     3541 caaacagaag atcatcgatg cccaggaaaa gcgcattgcc tcgctggacg ctgccaatgc
     3601 ccgcctcatg agtgccctca cacagctgaa agagaggtac agcatgcgag cccgtaacgg
     3661 cgtctccccc accaacccca ccaaattgca gattactgag aacggcgagt tcagaaacag
     3721 cagcaattgt taacctgcct gaggagaggg gactgtggtg gcccaggcag ggtctcggtc
     3781 aggaggctcc ccacagttgc agactagcct gcagtggagg gggcgcagga ctgatggagc
     3841 gtgagactga gggcacagtg cccccccacc tgaagtgggt gtgggtagag gcagtagaga
     3901 ctgcgctggg gagtggggac agcctgcaga gaggtctgcc tgccaactgt gtctctggtt
     3961 gttggatttg gtatgtggca ccttttcctc tttgaccagc cagccaggtg catgtacccc
     4021 ttaccctttg ccatggaggg agctacctgg aaagggctca agtaaggtct aggggccgct
     4081 gctgtgggtt tccctggctc ctgggacctg atggagtagt tggcaggcag agtggcccct
     4141 gcttatctct gctctagcct ctgccactgc atgcaactgc tcagggaccc ttcctggcgg
     4201 tgaggaactg aagaacagaa ctttgggtcc tgtgcccgtc ccaggctcga caccctccac
     4261 tctccttccc ttctttcctt gcattgccaa acagcactgc actttctctg ctgggccctc
     4321 acatccagtg gaggagccac agctccccac acgtcacctg tggtcctgcc tcatgctctt
     4381 ggaactccca gaggccagag agctgggcag aggtggccag gttgcaccat gcattatagc
     4441 tgccttctcc agggccccag tgtgtcccgg cacagtggcc ctgtggggag aagccagtcg
     4501 gtgctcaccc tgccaaggtg acctcttttc tctgatagtt taagagaaca gttctaagcc
     4561 cacaggccct gagaaggtgg ataactgtga ctttttttcc tttcacagta tgcattagaa
     4621 acaaaagccc gcttgctcgc ttgctggaac acagggcctt ttaaattggg cgtgcgcact
     4681 gcatgggaac tagcgaccct ggaggatggt agagttgctc cctctccaag acagcagcag
     4741 cctgcaccag gccccgtgtg tgcagtcgcc tctcctcacc ctcccagccc cagccaagga
     4801 cccaggcact gcaggcaggg aggggcacac cccacagctg gggctggttt tccccagctc
     4861 taggctgttc tgtagcatat ctgaccctcc ccctttgtgg aacagagatg ggcaggagct
     4921 tgggtctctc ttggattccc atctgttccc acactctaga ttccaagctc tggttctgag
     4981 tcacctaggg cagaagcctt tgcccaggca gcagaatggg actaggcaag ctgcactcaa
     5041 tgctcctaga gacctcacta gaaagggtgg aggtgtggcc tagctctgct gcaccccaga
     5101 ctcagtccac ggacaggtga gggtaaaggg tagatgccct ggactttagc tgtaacctac
     5161 aacccagtta ggctgcagac cagtgctggg agagggcgtg gccatcaagg gtcagacctc
     5221 aggaaggaag gaggtggggc tgaggtcctg ccactgcctc ttcctgcccc actcctatcc
     5281 acacccctgc acctgtgcat ttcagcaggg gtggcctctc gggcagggcc tggcctggcc
     5341 tgggtcttgc ccttccactg cccagggagc cctgttttcc tccccaccca cactgtcgcc
     5401 catgcctcgt taaagtgacc tctgtctgag cgcctcctag caatatgggg aggtccccag
     5461 gcctggacag gagagcgcag ggccagatgc aatggcccct ctggcggggt tattagctct
     5521 caggccgaga gccttattac ctagtgcaaa aactgtaaaa gtgtacagac tctccacaga
     5581 tttttatctt aattgcaagt ctgccgactt ttgtaaatgt tcttggtgtt tgactgtaac
     5641 ggaactattt cacccaaggg atgtacatag tcctttagtc ctggtgctgc aagggctggc
     5701 taggacactg ctctcccggt tgatacagcc tagagaacgg tgctgggcag gacaaagagc
     5761 tctgcagtct aggtgtctgt ctgtcttttt cctgcctggg gctttgattg gttggctttg
     5821 aagcatgctg ttgaggtggg aggttgatgg gggtacaggc cccaatgggg ccagtagagc
     5881 atcctcctgc cccacagctt tggggctgag ctctggccac agcaagggct ggaattgcca
     5941 gaggccctgc tctgggtagg ccctggtcac tgacacccag gctctgcagg agtgaggggc
     6001 ccctcccctg ccaacataga cacctgacct ttttattcaa cttgtatgtt aggacgaagg
     6061 aaactgccaa acttcctctg agcgaagact tctgactgcc caggggtggg ggtggggacc
     6121 agggccagag ctccacttgt gccccagcac ctgcctgagg gacactcctc cctcataccc
     6181 gtacgtctgg gagccagact gtccagggaa ccagcccctc ttttctatat actcagccac
     6241 aaggctaccg tcaaccccac tgtgcccagc tccccctttt gtaagtatgt gaaaaggaaa
     6301 aaggcaaacg tcggagtcag ccggagccct tccctccgcc gagactttaa ccctgtaata
     6361 atgtacagag aagttgttgg tgtttgaaga ctccgtgtgg ctgtgcaatt tctgtacatt
     6421 tgcaattaga aatattaaag atttatttag ctattttaa
//
