LOCUS       NM_001414977            2678 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus cytohesin 4 (Cyth4), transcript variant 1, mRNA.
ACCESSION   NM_001414977 XM_006242031
VERSION     NM_001414977.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2678)
  AUTHORS   Hofmann,I., Thompson,A., Sanderson,C.M. and Munro,S.
  TITLE     The Arl4 family of small G proteins can recruit the cytohesin Arf6
            exchange factors to the plasma membrane
  JOURNAL   Curr Biol 17 (8), 711-716 (2007)
   PUBMED   17398095
REFERENCE   2  (bases 1 to 2678)
  AUTHORS   Ogasawara,M., Kim,S.C., Adamik,R., Togawa,A., Ferrans,V.J.,
            Takeda,K., Kirby,M., Moss,J. and Vaughan,M.
  TITLE     Similarities in function and gene structure of cytohesin-4 and
            cytohesin-1, guanine nucleotide-exchange proteins for
            ADP-ribosylation factors
  JOURNAL   J Biol Chem 275 (5), 3221-3230 (2000)
   PUBMED   10652308
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 16, 2022 this sequence version replaced XM_006242031.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643299.32150.1,
                                           SRR26643298.40794.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-79                JAXUCZ010000007.1  112032782-112032860
            80-162              JAXUCZ010000007.1  112038307-112038389
            163-227             JAXUCZ010000007.1  112040245-112040309
            228-294             JAXUCZ010000007.1  112041449-112041515
            295-413             JAXUCZ010000007.1  112042684-112042802
            414-494             JAXUCZ010000007.1  112043771-112043851
            495-607             JAXUCZ010000007.1  112045313-112045425
            608-756             JAXUCZ010000007.1  112046931-112047079
            757-868             JAXUCZ010000007.1  112051317-112051428
            869-945             JAXUCZ010000007.1  112053569-112053645
            946-1017            JAXUCZ010000007.1  112054418-112054489
            1018-1172           JAXUCZ010000007.1  112054926-112055080
            1173-2678           JAXUCZ010000007.1  112055699-112057204
FEATURES             Location/Qualifiers
     source          1..2678
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..2678
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /note="cytohesin 4"
                     /db_xref="GeneID:500906"
                     /db_xref="RGD:1564842"
     exon            1..79
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     CDS             61..1245
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /note="isoform 1 is encoded by transcript variant 1;
                     pleckstrin homology, Sec7 and coiled/coil domains 4"
                     /codon_start=1
                     /product="cytohesin-4 isoform 1"
                     /protein_id="NP_001401906.1"
                     /db_xref="GeneID:500906"
                     /db_xref="RGD:1564842"
                     /translation="MDVCHADTAELSSGEARELQQIKWHRKQLLEDIQKLKDEIADVF
                     AQIDCFESTEESRMAQKEKEMCIGRKKFNMDPAKGIQYLTEHKLLTSDVQDIAQFLYK
                     GEGLNKTAIGTYLGEKDPINLQVLQAFVDCHEFANLNLVQALRQFLWSFRLPGEAQKI
                     DRMMEAFAARYCLCNPGVFRSTDTCYVLSFSVIMLNTGLHNPNVRDRPHFEHFVSMNR
                     GINSGSDLPEEQLRNLFDSIKSEPFSIPEDDGSDLTHTFFNPDREGWLLKLGGRVKTW
                     KRRWFILTDNCLYYFEFTTDKEPRGIIPLENLSVQKVDDPKKPFCLELYNPSCRGQKI
                     KACKTDGDGKVVEGKHESYRISAANAEERDQWIEAIRASITRVPFYDLLSARKKKIVG
                     KQ"
     exon            80..162
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            163..227
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            228..294
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            295..413
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            414..494
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            495..607
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            608..756
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            757..868
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            869..945
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1017
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            1018..1172
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..2678
                     /gene="Cyth4"
                     /gene_synonym="Pscd4; RGD1564842"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagcagcct ctgagccagc aagacaagca gctgggccgc cttcccccgg gggcttcaga
       61 atggatgtat gtcatgcaga tacagctgag ctcagcagtg gcgaggccag ggagctacag
      121 cagatcaaat ggcacaggaa gcagctactg gaggacatcc agaaactgaa ggatgaaatt
      181 gcagacgtgt ttgcccaaat tgactgcttc gagagcacag aggagagccg gatggcgcag
      241 aaagagaagg agatgtgcat cgggagaaag aaattcaaca tggaccctgc taagggcatc
      301 cagtatctca ctgagcacaa gctgctgacc tctgatgttc aggacatcgc ccaattcctg
      361 tacaagggtg aaggtctcaa caagacagcc attggcacct acttggggga aaaggacccc
      421 atcaacttgc aggtcctgca ggccttcgtg gattgccacg agtttgccaa cctcaacctc
      481 gttcaggccc tcaggcagtt cctgtggagc ttcaggctgc caggtgaggc ccagaagatt
      541 gaccgcatga tggaggcctt tgctgctcgc tactgcctct gtaaccctgg agtcttccgg
      601 tccacagaca cctgctacgt gctgtccttc tctgtcatca tgctcaacac cggcctccac
      661 aaccccaatg tgcgggacag accccacttc gagcactttg tgtccatgaa tcgcggcatc
      721 aacagtggca gtgacctgcc tgaggagcag ctgcggaacc tgtttgacag catcaagagt
      781 gagcccttct ccatccccga agatgatggt agtgacctta ctcacacctt cttcaatcct
      841 gaccgtgaag gatggctact caagctgggg ggccgtgtga agacatggaa gcgacgctgg
      901 ttcattctca cggacaactg cctctactac tttgagttca ccactgacaa agagcctcgg
      961 gggatcatcc ccctggagaa cctctctgtg cagaaggtgg atgaccccaa gaagccgttc
     1021 tgcctggagc tgtacaaccc cagctgccgg ggccagaaga taaaggcatg caagacggac
     1081 ggggatggca aggtggtgga aggcaaacac gaatcctacc gcatctcagc tgccaatgcc
     1141 gaggagcgcg accagtggat cgaggccatc agggccagca tcacccgagt tcccttctat
     1201 gatctattgt ctgctcggaa aaagaagata gtgggcaagc agtgaacttc tgggaggcag
     1261 tgctggcaac cccgtgggaa ccatggtacc aggagacaca gacccactgt gcctgctcct
     1321 gctcacaaac ctgcccctcc acatcattgg aactggctgt ttggggctgt ggatcctcag
     1381 aaagcacaga gttcacaggg agcttgacag gaagaactta tgaagctcta tctgggacca
     1441 ctgtgtgtgt ggatggccag cctagagccc ttctgtgtat ctcacccttt ccctcccatc
     1501 aggaggacta tggattccct ggaggcttcc acctcagaag ttctccttcc ctcagcttga
     1561 gccaggctgt ctctgccatg gacaagtatc agcgttcatc taacttggag ctcggaagct
     1621 tcagacaaac ccctccactg cacacagccc tcctctgggt ctttcgaatc atagagtttg
     1681 aataggaaac atcttggtcc agtaacttta tggtcagctt ggtttccaga gggagctggg
     1741 ataccaggtg actgaatggg acagactgag ctggaagatt ctgaggacac tgccagcatt
     1801 attcccaagg gtgctgacct gagacgagca gaggagacag accctggagg ctctggcagt
     1861 ctctatggct tgccagtctg gcgtacaacc aaggaaaatg ggagaagaga atgcttcagg
     1921 ttgtgcccac caggacagct gcttggaggc cacagccagc ctgtggtaac acaggactca
     1981 ggcttggaca gactctcagt catggtgcca ttgctggcga cctggccagc agagctgagg
     2041 tagtcagggg ctgcaggatg ggcccctgtt cctgcctcct gacagagcaa ggccagcttt
     2101 gcatacaggc tgctctgtcc ccagggaggt ccctcttggg gggatatttc ttccccagag
     2161 cgtttgtacc tcctcctgac tgaagagacc gaaggaggga aagttcctca gcaagggagc
     2221 aagaaatggg gctccctgtg ccctgggcca gcctgggctc tgggaaggag cagcaggtgg
     2281 ctaggctacc cttgtcctct gcaggagcac acatgggtgc actgtctaca gggtaggaag
     2341 agaagtgctg tggggtgggg tggggtgggg tggggtgggg taagacgcct gtctcaggag
     2401 gaacactcgg ctgagagctg gggcatcggc aatggagccc ttgctggact attgaagact
     2461 ttctggtgag ctgagtccac accagctgct cccatttgtg ggttaaggga cccgaaagtc
     2521 ttcctctgcc tctggcatgt gtgtgtgtac agaggctgtc ggactcttat cccttcccct
     2581 ctttggtcct cagctccttc cccagctcca aggtggggga gcatcttttt ctttcctgtt
     2641 gtaacactta gaagcaagaa taaaagctca tgactcaa
//
