LOCUS       XM_039089957            3802 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus cytochrome P450, family 3, subfamily
            a, polypeptide 73 (Cyp3a73), transcript variant X17, mRNA.
ACCESSION   XM_039089957
VERSION     XM_039089957.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051347.1) annotated using gene prediction method: Gnomon.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039089957.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3802
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3802
                     /gene="Cyp3a73"
                     /note="cytochrome P450, family 3, subfamily a, polypeptide
                     73; Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 44 Proteins, and 96% coverage of the
                     annotated genomic feature by RNAseq alignments"
                     /db_xref="GeneID:498198"
                     /db_xref="RGD:1595705"
     CDS             1405..2919
                     /gene="Cyp3a73"
                     /codon_start=1
                     /product="cytochrome P450 3A2-like isoform X10"
                     /protein_id="XP_038945885.1"
                     /db_xref="GeneID:498198"
                     /db_xref="RGD:1595705"
                     /translation="MDLVSALSLETWLLLAIILVLFYRFGTRTHGIFKKQGIPGPKPL
                     PFLGTVLNYYRGLWKFDMECYKKCGKIWGLFDGQTPVFAIMDTEMIKSVLVKECFSVF
                     TNRRNIGPVGIMSKSISVAKDEEWKRYRAFLSPTFTSGRLKEMFPIIEHYGDILVKYL
                     KQKVEKGKPLAMKEVFGAYSMDVITSTSFEVNINSINNPKDPFVEKVKKFQRFDFFDP
                     LFLSVVLFPFLTPIYEMLNICLFPKDSVAFFQKFVYRMKQTRLDSKHKHRVDFLQLMM
                     NAHNNSKDKVSHKALSDIEIVAQAIIFIFASYETTSSTLSFVLYSLATHPDSQKKLQE
                     EIDRALPNKAPPTYDTVMEMEYLDMVLNETPRLYPIGYRLERVCKKDIKLDGVFIPKG
                     SVVMIPFYTLQHDPQHWPEPEEFLPERFSKENKGSIDPYVYLPFGNGPRNCIGMRFAL
                     MNMKLALTKVLQNFSFQLCEETQIPLKLSRQRLFGPEKPIVLKVVPRDAVITGA"
ORIGIN      
        1 tctacttaat tttctaagaa aaaattttgg tagcagcaat gactttgtac tctcttccca
       61 gtcccaacct cacaaatacc tcccctagta cctccttccc ttctcctctg tgtaggtgaa
      121 acctgttcta ggttatgttc ctgggatatc aagtctcagc aagtgtagat gaatcctttc
      181 ttactgaggc tcttccaggt agtctagttt atggaaagga atctaatggt aggtagcaga
      241 tagtttctgc tgcaattgtt gggggaccca agaagaacaa gctgcacatg tgctgtataa
      301 gtgtagggtc ctaggtccag cctctgaatg ttctttggtt ggtggttcag tctctgtgag
      361 acccagggtc ccaggttagt tgattcccta gatcttcttg tggtgtcctt gaccactctg
      421 gctcactgaa tcctgccccc actcttccac gggactcttg gtgcttcccc tgatgattga
      481 ctatttctat ctgcatttta atagctattt ttattaaata aatatatctc tctccctgtc
      541 tgtctgtctg tctgtctgtc tgtctgtctg agtgtctctc tctctctctc tctgtgagac
      601 aactttatgt atagaaaaca ttctggttaa atctcctcac ctcttcctta ccccaccctt
      661 gtcacactca gttcttccct gcaaagctcc ttcccatatt catgacttgt tttgtgtcct
      721 gaagacttta tctagtttcc tgtgtgtgtg actgtggatt tggaaccatc cattcaagtc
      781 tgtgggtcgc cagttatcag tgggttcaga actgagttca attactccct ctcagcaatg
      841 acttgcaggg cctgtctctt tttccctggc accatagtca agcattggca ggtgatgaat
      901 tttggtggat agatgtagta gatatttttg aggcatgttt tcccatatcc catgctgggc
      961 tcaaacaatc catgtggctt tgaactttgt ctttcaactt ctaatccccc tgcttctatt
     1021 ctctgagtgc atttttgaat gaagccacca gaggtgaggg gatatttcat ggtatttatt
     1081 tgcttgaatt tctgatagaa actaagaacc tttagtctta cccatattcc attgttgttc
     1141 cctgatgcca gacggaatgt tagctcaaag gaggtcaaag aggctgtaga tgaactgtct
     1201 aggggaagag agtaccaagg tccaggtgag ggagatgtga tccatctatt ggctggatcc
     1261 ctggtgccac ccaccttccc agcatttaag tactgcaggc tggcctcagt gcagcagtgt
     1321 gggcagaagg gaagccctgc agagggtcac aggcacaggt agaaggagaa cacagagaag
     1381 taaattgctg actgacaagc agggatggac ctggtttcag ctctctcact ggaaacctgg
     1441 ctcctcctag caatcatcct tgtgctcttc taccgatttg ggacccgtac acatggaatt
     1501 tttaagaaac agggaattcc tgggccaaaa cctctgcctt ttttaggcac tgtgctgaat
     1561 tactacaggg gcttatggaa attcgacatg gagtgctata agaagtgtgg gaaaatatgg
     1621 gggttgtttg atggtcaaac gcctgtgttt gccatcatgg acacagaaat gatcaagagt
     1681 gtgctagtga aggaatgctt ttctgtcttc acaaaccggc ggaatattgg cccagtgggg
     1741 atcatgagca aatccatctc tgtagctaag gacgaggagt ggaaaagata tagagccttc
     1801 ctgtccccca catttaccag tggaagactc aaggagatgt tccccatcat cgaacactat
     1861 ggagacattt tggtaaagta cttgaagcaa aaggtagaga aaggcaagcc tcttgctatg
     1921 aaagaagtgt ttggtgccta cagcatggat gttattacca gcacatcatt tgaagttaac
     1981 atcaattcca tcaacaaccc aaaggatcct tttgtggaga aagtcaagaa attccaaaga
     2041 tttgactttt ttgatccgtt gttcttgtca gtagtactct ttccattcct cacccccata
     2101 tatgagatgt taaatatctg cctcttccca aaggattcag tagcattttt ccaaaaattt
     2161 gtgtacagaa tgaagcaaac ccgcctggat tctaagcata agcaccgagt ggattttctt
     2221 cagctgatga tgaatgctca taataattcc aaagacaaag tgtctcataa agccctgtct
     2281 gacattgaaa ttgtagccca ggcaattatc tttatttttg ctagctatga aaccaccagc
     2341 agcacacttt cctttgtctt gtattccctg gccactcacc ctgacagcca gaagaaactg
     2401 caggaggaaa tcgacagggc tctacccaat aaggcacctc ccacctatga tactgtgatg
     2461 gaaatggagt atctggatat ggtgttgaat gaaaccccca gattgtatcc aattggttat
     2521 agacttgaga gagtctgtaa aaaagatata aaacttgatg gtgtgtttat acccaaaggg
     2581 tcagtggtga tgattccatt ttatactctt caacatgacc cacagcactg gccagagcct
     2641 gaggaatttc ttccagaaag gttcagcaag gagaacaagg gcagcattga tccttatgta
     2701 tatctgccct ttggaaatgg acccaggaac tgtattggca tgaggtttgc tctcatgaat
     2761 atgaaacttg ctctcactaa agttctgcaa aacttctcct tccagctttg tgaggaaaca
     2821 cagatacctc tgaaattaag tagacaaaga ctttttggac cagaaaaacc cattgttctt
     2881 aaggttgtgc cacgggatgc agtcataact ggagcatgac ttttcctcaa ggaattttat
     2941 tagactctta agaaagtcag tgtctaagaa cattgaactt attaatttac ttcaagaatg
     3001 aattccagac aaaactgggg cttaactgac tgttcttgat gcatggttaa tgagtcagta
     3061 catttattga tctttctcag tgtctataca aaataccatc taataaaaag gagacaataa
     3121 gtaagtgaca gaacatgaaa tttaccattg ctgattctca tgggaccacc tctatccaca
     3181 tctgcttgtc tttgttaatt tttgaacgat tttgatagta atcatgtctc tataatttga
     3241 tcaataatat tttgatgtaa aagtgaacta ttgtgataac tcttttgtag atttggtatc
     3301 aaatgcttta gttgcaatat tctagaatgg aaagtatcct taaatatcct ttaaaaaatc
     3361 ctgtttaact gtgttttaaa atattctttg tgagctttat tgaatgtatt ttgatcatat
     3421 taattccttt ccttcaaatg ttcccagatt ctatccaatc ttctttccca accactttat
     3481 atttctcaca gtgtttcaaa acaaaacaaa aactatggag tctagtttgt gttggatatc
     3541 ttttcctcgt gtgaggcctg ccatggagtg aaacttgtat gacccccata gacaaaaacc
     3601 tgacctttca tctctcaggt actctctgct tacagtgagt ccttagctag agggaggact
     3661 ttcaacttgt cgccactagc attttgtctt gagtttgtgg agatcatgtg aatttgtcaa
     3721 agtctctgtg agttcatgta cacacatgca tgcatgttgt gtctgtcaat gctgtttcct
     3781 taaagtcatc tactacctct ga
//
