LOCUS       NM_134369               1644 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus cytochrome P450, family 2, subfamily t,
            polypeptide 1 (Cyp2t1), mRNA.
ACCESSION   NM_134369
VERSION     NM_134369.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1644)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 30, 2020 this sequence version replaced NM_134369.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF368269.1, SRR26360172.754537.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-234               JAXUCZ010000001.1  91575510-91575743
            235-397             JAXUCZ010000001.1  91576010-91576172
            398-547             JAXUCZ010000001.1  91576490-91576639
            548-708             JAXUCZ010000001.1  91576886-91577046
            709-885             JAXUCZ010000001.1  91577787-91577963
            886-1027            JAXUCZ010000001.1  91578038-91578179
            1028-1215           JAXUCZ010000001.1  91578286-91578473
            1216-1357           JAXUCZ010000001.1  91578695-91578836
            1358-1644           JAXUCZ010000001.1  91578929-91579215
FEATURES             Location/Qualifiers
     source          1..1644
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1644
                     /gene="Cyp2t1"
                     /note="cytochrome P450, family 2, subfamily t, polypeptide
                     1"
                     /db_xref="GeneID:171380"
                     /db_xref="RGD:620086"
     exon            1..234
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..1539
                     /gene="Cyp2t1"
                     /note="cytochrome P450 monooxygenase CYP2T1"
                     /codon_start=1
                     /product="cytochrome P450, family 2, subfamily t,
                     polypeptide 1"
                     /protein_id="NP_599196.2"
                     /db_xref="GeneID:171380"
                     /db_xref="RGD:620086"
                     /translation="MVTCEATLLLLLILTLMLMSWGWLAHQARARMQKDLPPGPAPLP
                     LLGNLLQLQSGHLDRVLMELSSRWGPVFTVWLGPRPAVVLSGYAALRDALVLQADAFS
                     GRGSMAVFERFTHGNGIVFSNGPRWRTLRNFALGALKEFGVGTSTIEERILEETACVL
                     DEFQATMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRLLDLFSDNFRIMSSR
                     WGETYNMFPSFMDWIPGPHHRIFKNFQELRLFISEQIQWHRQSRQTGEPRDFIDCFLE
                     QMDKEHQDPESHFQDETLVMTTHNLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEEL
                     DATVGRTRAPSLADRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNLRNHFLHKGT
                     FVIPLLVSAHRDPTQFKDPDHFNPTNFLDDQGEFQNNDAFMPFAPGKRMCLGAGLARS
                     EIFLFLTAILQKFSLLPVGSPADIDLTPQCTGLGNVPPAFQLRLVAR"
     exon            235..397
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            398..547
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            548..708
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            709..885
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1027
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            1028..1215
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1357
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
     exon            1358..1644
                     /gene="Cyp2t1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctaccaact aaacggctac cacagcgtgc aggacctcag acaggatggt cacctgtgag
       61 gcaacgcttc tgctgctgct gattctaacg ctaatgctta tgtcgtgggg ctggttggcc
      121 caccaagctc gagctcggat gcagaaagac ttgccccctg ggcctgcacc gcttcccttg
      181 ctggggaatt tgttgcagct acagtctgga cacttggacc gtgtgctcat ggagctctcc
      241 agccgctggg gcccagtgtt caccgtgtgg ctgggcccgc gccctgccgt ggtgctgagc
      301 ggctatgcgg cgctgcggga tgcattagta ctgcaggcag atgctttctc tggccgcggg
      361 tccatggctg tcttcgaacg cttcacccac ggaaatggca tagtgttttc taatgggccg
      421 cgttggcgta cgcttcgcaa ctttgcactt ggagcactga aggagtttgg cgtgggtacg
      481 agtaccattg aggagcgcat cctggaggag accgcatgtg tgctggacga atttcaagcc
      541 accatgggag ctccatttga ccctcggcgg ctactggaca acgctgtatc caacgtcatt
      601 tgtactgtgg tcttcggaaa gcgctacaac tatggagacc cagagttcct gaggctcctg
      661 gacctcttca gtgacaattt ccgtatcatg agttcccgat ggggtgagac atacaacatg
      721 ttcccatcct tcatggactg gatccctggt ccccaccacc gaatcttcaa aaatttccaa
      781 gagcttcggc tcttcatctc tgagcaaatt cagtggcacc ggcagtcacg acagactggg
      841 gagccccgtg acttcattga ttgtttcctc gaacaaatgg ataaggaaca tcaggacccg
      901 gaaagccatt tccaggatga gacactggtg atgactactc acaatctttt ctttggtggc
      961 acggagacca caagcaccac tctgcgttat gggctcctca ttatgctcaa gtaccctgag
     1021 gtggcagcca aggtgcaaga ggagctggac gccactgtag gccggacccg tgcccctagc
     1081 ctagcagacc gtgcccacct gccctacacc aatgcggtgc tgcatgagat ccagcgcttc
     1141 atcagcgtgc taccactggg actgcctcgg gccctcatcc gagacgtaaa cctcaggaac
     1201 catttcctgc acaagggcac cttcgtcatt cccttgcttg tgtctgcaca tcgggatccc
     1261 acccaattca aggaccctga ccatttcaat cccaccaatt tcctggatga ccagggcgag
     1321 ttccagaaca acgacgcctt catgcccttt gccccaggaa agcggatgtg cctgggtgct
     1381 ggcctagccc gctctgagat cttcctcttc ctgacggcta tcctgcagaa gttctccctg
     1441 ctccctgtgg gaagtcctgc tgacatcgac cttactccac agtgcactgg tctaggcaat
     1501 gtgcccccag ccttccagct ccgcttggtg gcccgctgag gttgggcttc agtattctga
     1561 tctcagtggc cttgatatcc tcactgccct aactgtacgt gtgaatctct ttacggagag
     1621 gaatacaagt gtgtgcagct ctga
//
