LOCUS       NM_012787               1859 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus cytochrome P450, family 2, subfamily g,
            polypeptide 1 (Cyp2g1), mRNA.
ACCESSION   NM_012787 XM_001077589 XM_341809
VERSION     NM_012787.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1859)
  AUTHORS   Nef,P., Larabee,T.M., Kagimoto,K. and Meyer,U.A.
  TITLE     Olfactory-specific cytochrome P-450 (P-450olf1; IIG1). Gene
            structure and developmental regulation
  JOURNAL   J Biol Chem 265 (5), 2903-2907 (1990)
   PUBMED   2406242
REFERENCE   2  (bases 1 to 1859)
  AUTHORS   Nef,P., Heldman,J., Lazard,D., Margalit,T., Jaye,M., Hanukoglu,I.
            and Lancet,D.
  TITLE     Olfactory-specific cytochrome P-450. cDNA cloning of a novel
            neuroepithelial enzyme possibly involved in chemoreception
  JOURNAL   J Biol Chem 264 (12), 6780-6785 (1989)
   PUBMED   2708343
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Apr 13, 2016 this sequence version replaced NM_012787.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: M33296.2, SRR26643293.2084.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-180               JAXUCZ010000001.1  91273309-91273488
            181-343             JAXUCZ010000001.1  91274085-91274247
            344-493             JAXUCZ010000001.1  91275825-91275974
            494-654             JAXUCZ010000001.1  91278236-91278396
            655-831             JAXUCZ010000001.1  91278769-91278945
            832-973             JAXUCZ010000001.1  91280818-91280959
            974-1161            JAXUCZ010000001.1  91282286-91282473
            1162-1303           JAXUCZ010000001.1  91282593-91282734
            1304-1859           JAXUCZ010000001.1  91283943-91284498
FEATURES             Location/Qualifiers
     source          1..1859
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1859
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /note="cytochrome P450, family 2, subfamily g, polypeptide
                     1"
                     /db_xref="GeneID:25251"
                     /db_xref="RGD:2477"
     CDS             1..1485
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /EC_number="1.14.14.1"
                     /note="cytochrome P450-OLF1; cytochrome P450 olfactive;
                     Cytochrome P450, an olfactory-specific steroid
                     hydroxylase; cytochrome P450, subfamily 2G, polypeptide 1;
                     cytochrome P-450"
                     /codon_start=1
                     /product="cytochrome P450 2G1"
                     /protein_id="NP_036919.1"
                     /db_xref="GeneID:25251"
                     /db_xref="RGD:2477"
                     /translation="MALGGAFSIFMTLCLSCLLILIAWKRTSRGGKLPPGPTPIPFLG
                     NLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRG
                     EMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEEL
                     HKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQ
                     LYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNPRDFIDCFLIKMY
                     QDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQV
                     IGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVY
                     PLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRICVGEALARMELF
                     LYFTSILQRFSLRSLVPPADIDIAHKISGFGNIPPTYELCFMAR"
     exon            1..180
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            181..343
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            344..493
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            494..654
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            655..831
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            832..973
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1161
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1303
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1859
                     /gene="Cyp2g1"
                     /gene_synonym="CYPIIG1; P-450olf1; P450-OLF1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcactgg gaggggcctt cagcatcttt atgacgctct gcttgtcttg cctgctcatc
       61 ctgatagctt ggaagcgaac cagcagggga ggaaagctgc ctcccggccc cacaccaata
      121 ccatttttgg ggaacctgtt acaagtacgc attgatgcca catttcagtc ctttctgaag
      181 ctccagaaaa agtatggctc tgtgttcacc gtatactttg gcccaaggcc agtggttatc
      241 ttatgtggac atgaggcagt gaaggaggcc ctggtggacc aggcagatga cttcagtggt
      301 cgtggtgaaa tgcctacact agagaagaac tttcaaggtt atggtttagc tctgtccaat
      361 ggagaacgat ggaagattct tcggcgtttt tccctgactg tccttcgaaa ctttggaatg
      421 gggaagcgaa gcattgagga gcggatccag gaggaggccg gctacctact ggaggaactc
      481 cataaggtca agggagctcc catagatccc accttctacc tgagtcgcac tgtgtccaat
      541 gtcatctgtt ccgtcgtctt tggaaaacgt ttcgactatg aggaccagcg tttccggagc
      601 ctcatgaaga tgatcaatga gagctttgtg gagatgagca tgccctgggc acagttatat
      661 gatatgtact ggggagtcat acagtatttt ccaggaagac acaaccgcct ctacaacttg
      721 atagaagagc ttaaggactt cattgcttcc agggtcaaga tcaatgaagc atcctttgac
      781 ccctcaaatc ctagggactt catcgactgc tttcttatta agatgtacca ggataaaagt
      841 gacccacact cagaattcaa cctcaagaac ttggttctca ccaccctcaa cctcttcttt
      901 gctggcacgg aaactgtgag ttccacacta cgatatggat tcttgttgct aatgaagtac
      961 cccgaggtgg aggccaagat ccatgaggag attaaccagg tgattggaac acaccgtacc
     1021 ccaagagtgg atgaccgggc caagatgccc tacactgatg ctgtcatcca tgagatacag
     1081 agattgacag atattgtgcc tctgggtgtt ccccataatg tcatacggga cactcatttc
     1141 cgaggctact tcctacccaa gggtacagat gtgtatcccc tgattggctc agtcctcaaa
     1201 gatcccaaat acttccgcta cccagaagct ttttatcctc agcacttcct ggatgaacaa
     1261 gggcgcttca agaagaatga tgcctttgtg gccttttcct ctggaaagcg catctgtgtc
     1321 ggggaggccc tggcccgtat ggagctcttc ctctacttca cctccatcct tcagaggttc
     1381 tccttacgtt ctctggtgcc tcctgctgat atcgacatcg ctcacaaaat ctcaggcttt
     1441 ggcaacattc ccccaacata tgagctctgc ttcatggccc gctgagtgcc cacttcgaga
     1501 ccaaccaaga gtcaattgag agaggagctc tgctggagtt cacgcacacc cgatctccct
     1561 ccaaccctcc ctactcatct aagagaagtc gctctcattg ctgtgctgag accacgggtc
     1621 aggagaggtg tctgcaaaaa catggctgga tggtatcaag cagggttcta gccacagtct
     1681 cggtttcgga gagccctgaa tttctcaacc ttggtctcgg tgggcagcaa acttacagat
     1741 gctgtgggtt tacataatct attgactttg ccctgatatt gaccagaatg tactccgcaa
     1801 ttctttcctg tttgctttta tttctcctcc ccaataaaga actcaagact attgaccat
//
