LOCUS       NM_001271354            1989 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus cytochrome P450, family 2, subfamily c,
            polypeptide 24 (Cyp2c24), mRNA.
ACCESSION   NM_001271354 XM_003753415 XM_574665
VERSION     NM_001271354.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1989)
  AUTHORS   Merrick,B.A., Chang,J.S., Phadke,D.P., Bostrom,M.A., Shah,R.R.,
            Wang,X., Gordon,O. and Wright,G.M.
  TITLE     HAfTs are novel lncRNA transcripts from aflatoxin exposure
  JOURNAL   PLoS One 13 (1), e0190992 (2018)
   PUBMED   29351317
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1989)
  AUTHORS   Wang,H., Zhao,Y., Bradbury,J.A., Graves,J.P., Foley,J.,
            Blaisdell,J.A., Goldstein,J.A. and Zeldin,D.C.
  TITLE     Cloning, expression, and characterization of three new mouse
            cytochrome p450 enzymes and partial characterization of their fatty
            acid oxidation activities
  JOURNAL   Mol Pharmacol 65 (5), 1148-1158 (2004)
   PUBMED   15102943
REFERENCE   3  (bases 1 to 1989)
  AUTHORS   Marill,J., Cresteil,T., Lanotte,M. and Chabot,G.G.
  TITLE     Identification of human cytochrome P450s involved in the formation
            of all-trans-retinoic acid principal metabolites
  JOURNAL   Mol Pharmacol 58 (6), 1341-1348 (2000)
   PUBMED   11093772
REFERENCE   4  (bases 1 to 1989)
  AUTHORS   Zaphiropoulos,P.G.
  TITLE     Differential expression of cytochrome P450 2C24 transcripts in rat
            kidney and prostate: evidence indicative of alternative and
            possibly trans splicing events
  JOURNAL   Biochem Biophys Res Commun 192 (2), 778-786 (1993)
   PUBMED   7916606
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Sep 19, 2012 this sequence version replaced
            XM_003753415.1, XM_574665.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.3798.1,
                                           SRR26643286.4907.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMEA5760494
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               JAXUCZ010000001.1  246286341-246286535
            196-358             JAXUCZ010000001.1  246302195-246302357
            359-508             JAXUCZ010000001.1  246302903-246303052
            509-669             JAXUCZ010000001.1  246305439-246305599
            670-846             JAXUCZ010000001.1  246337073-246337249
            847-988             JAXUCZ010000001.1  246343465-246343606
            989-1176            JAXUCZ010000001.1  246344739-246344926
            1177-1318           JAXUCZ010000001.1  246345988-246346129
            1319-1989           JAXUCZ010000001.1  246347937-246348607
FEATURES             Location/Qualifiers
     source          1..1989
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..1989
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /note="cytochrome P450, family 2, subfamily c, polypeptide
                     24"
                     /db_xref="GeneID:499353"
                     /db_xref="RGD:1563697"
     exon            1..195
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1500
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /codon_start=1
                     /product="cytochrome P450, family 2, subfamily c,
                     polypeptide 24"
                     /protein_id="NP_001258283.1"
                     /db_xref="GeneID:499353"
                     /db_xref="RGD:1563697"
                     /translation="MDPVLVLVLTLSCLLLLSLWRQSSGRGKLPPGPTPLPIIGNILQ
                     IDVKDISKSFTNFSKIYGPVFTLYFGPKPTVVVHGYEAVKEALDDLGEEFSGRGSFPI
                     VERMNNGLGVIFSNGTKWKELRHFSLMTLRNFGMGKRSIEDRIQEEASCLVEELRKTN
                     GSLCDPTFILSCAPSNVICSVVFHNRFDYKDENFLNLMEKLNENFKILNSPWMQVCNA
                     LPAFIDYLPGSHNRVIKNFAEIKSYILRRVKEHQETLDMDNPRDFIDCFLIKMEQEKH
                     NPRTEFTIESLMATVSDVFVAGSETTSTTLRYGLLLLLKHTEVTAKVQEEIDHVIGRH
                     RRPCMQDRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLVTSLT
                     SVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSTGKRMCVGEALARMELFLLLT
                     TIVQNFNLKSFVDTKDIDTTPMANTFGRVPPSYQLCFIPR"
     exon            196..358
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            359..508
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            509..669
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            670..846
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            847..988
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1176
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1318
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..1989
                     /gene="Cyp2c24"
                     /gene_synonym="RGD1563697"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaatcttctt gagaagagaa ggctgtcatg gatccagtcc tggtcctggt gctcactctc
       61 tcctgtctgc ttcttctctc actgtggaga cagagctctg ggagagggaa gctccctcct
      121 ggcccaactc ctctcccaat cattggaaac atccttcaga tagatgtgaa ggacatcagc
      181 aaatccttca ccaatttctc aaaaatttat ggccctgtgt tcactctgta ctttggtccg
      241 aagcctactg tggtggtaca tggatatgaa gcagtaaagg aagccctgga tgatcttgga
      301 gaggagtttt ctgggagggg tagtttccca attgttgaaa gaatgaataa tggccttggg
      361 gtcattttca gcaatggaac aaaatggaag gagcttcggc atttctcact tatgaccttg
      421 agaaattttg ggatggggaa gaggagcatc gaggatcgca ttcaagagga agcctcctgt
      481 cttgtggaag agctaagaaa aacaaatggc tcactctgtg atcccacatt catcctgagc
      541 tgtgctccct ccaacgtgat ctgctcagtt gttttccata atcgttttga ttataaagat
      601 gagaatttcc ttaacttgat ggagaaactc aatgaaaact ttaaaatctt gaactcccca
      661 tggatgcagg tttgcaatgc tctccctgcc ttcatcgatt atctcccagg aagccataat
      721 agagtaatta aaaattttgc tgaaataaaa agttatattt tgagacgagt gaaagaacat
      781 caggaaacac tggacatgga caatcctcgg gactttattg actgtttcct gatcaaaatg
      841 gaacaggaaa aacacaatcc ccgtactgag tttactattg aaagcttgat ggctactgta
      901 agtgatgtat ttgtagctgg atcagaaacc acaagcacta ccctgagata tggactcttg
      961 ctcctactga aacacacaga ggtcacagct aaagtccagg aagagattga tcacgtgatt
     1021 ggcagacaca ggaggccctg catgcaggac aggacccgca tgccctacac agatgcgatg
     1081 gtgcacgaaa tccagagata tattaacctc atccccaaca atgtgcccca tgcagctacc
     1141 tgtaatgtta gattcagaaa ttatgtaatt cccaagggca cggacttagt aacatcactg
     1201 acttctgtgc tacatgatga caaagaattt cccaacccag aagtatttga cccaggccat
     1261 tttctggatg agaatgggaa ctttaagaag agtgactact ttatgccttt ctcaacagga
     1321 aagcgaatgt gcgtgggaga ggccctggct cgcatggagc tgtttttgct tctgaccacc
     1381 attgtacaga attttaacct gaaatctttt gttgatacaa aggacattga cactactcca
     1441 atggctaata cctttggccg tgtaccacct tcataccagc tgtgcttcat tcctcgttaa
     1501 agcagagcac actgggctgt tgctatgctg gtgtctgtga ctaatcaggg gcaatccagt
     1561 ttccactgtt aggaacatct ctctcaattc tcctctcaca tctcttcatt ctctcacaat
     1621 acagttatca tccatctttg tttaagaggt tttcccagag ttatcacgca aatctatcct
     1681 ttgtctccca cagtctataa cacttatatt gactgtgaac tgtactaaga catgtgctgg
     1741 gttactaata tgttatgggt gtaatacaga atagttcaac tgagagccat atcttctttg
     1801 cttgattcaa aataaaagga gttattaact gaagagtcat ttttcaggct ttttctttta
     1861 cacataatac atataaggag tgaaaaagta aggttagtgt tataatgcat aatgggatat
     1921 catcttttac ctattaggat ggggatttgg aaattaaaat gaaactgaaa ataaaagaat
     1981 tggtaataa
//
