LOCUS       NM_138514               1721 bp    mRNA    linear   ROD 29-JUL-2024
DEFINITION  Rattus norvegicus cytochrome P450, family 2, subfamily c,
            polypeptide 13 (Cyp2c13), mRNA.
ACCESSION   NM_138514
VERSION     NM_138514.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Eguchi,H., Westin,S., Strom,A., Gustafsson,J.A. and
            Zaphiropoulos,P.G.
  TITLE     Gene structure and expression of the rat cytochrome P450IIC13, a
            polymorphic, male-specific cytochrome in the P450IIC subfamily
  JOURNAL   Biochemistry 30 (45), 10844-10849 (1991)
   PUBMED   1834171
REFERENCE   2  (bases 1 to 1721)
  AUTHORS   Yeowell,H.N., McClellan-Green,P.D., Negishi,M. and Goldstein,J.A.
  TITLE     Characterization of a cDNA for the unexpressed form of cytochrome
            P-450g from the (-g) rat and differentiation of its mRNA from that
            of the (+g) phenotype using specific oligoprobes
  JOURNAL   Biochemistry 29 (3), 713-718 (1990)
   PUBMED   2337591
REFERENCE   3  (bases 1 to 1721)
  AUTHORS   Zaphiropoulos,P.G., Strom,A., Robertson,J.A. and Gustafsson,J.A.
  TITLE     Structural and regulatory analysis of the male-specific rat liver
            cytochrome P-450 g: repression by continuous growth hormone
            administration
  JOURNAL   Mol Endocrinol 4 (1), 53-58 (1990)
   PUBMED   2325668
REFERENCE   4  (bases 1 to 1721)
  AUTHORS   McClellan-Green,P.D., Negishi,M. and Goldstein,J.A.
  TITLE     Characterization of a cDNA for rat P-450g, a highly polymorphic,
            male-specific cytochrome in the P-450IIC subfamily
  JOURNAL   Biochemistry 28 (14), 5832-5839 (1989)
   PUBMED   2775738
REFERENCE   5  (bases 1 to 1721)
  AUTHORS   Matsumoto,T., Emi,Y., Kawabata,S. and Omura,T.
  TITLE     Purification and characterization of three male-specific and one
            female-specific forms of cytochrome P-450 from rat liver microsomes
  JOURNAL   J Biochem 100 (5), 1359-1371 (1986)
   PUBMED   2434473
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from M32277.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J02861.1, M32277.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..1721
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /note="cytochrome P450, family 2, subfamily c, polypeptide
                     13"
                     /db_xref="GeneID:171521"
                     /db_xref="RGD:620363"
     exon            1..179
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..1484
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /EC_number="1.14.14.1"
                     /note="cytochrome P450, 2c38; UT-5; P-450g; P450-G;
                     CYPIIC13; cytochrome P-450g; cytochrome P450-G; cytochrome
                     P450-UT-5; CYP2C13 (+); cytochrome P450 g (+); cytochrome
                     P450 2C13, male-specific-like"
                     /codon_start=1
                     /product="cytochrome P450 2C13, male-specific"
                     /protein_id="NP_612523.1"
                     /db_xref="GeneID:171521"
                     /db_xref="RGD:620363"
                     /translation="MDPVVVLLLSLFFLLFLSLWRLSSGRGKLPPGPTPLPIIGNFFQ
                     VDMKDIRQSLTNFSKTYGPVYTLYVGSQPTVVLHGYEALKEALVDHGEEFSGRGRLPI
                     CEKVAKGQGIAFSHGNVWKATRHFTVKTLRNLGMGKGTIEDKVQEEAKWLVKELKKTN
                     GSPCDPQFIMGCAPGNVICCIILQNRFDYEDKDFLNLIEKVNEAVKIISSPGIQVFNI
                     FPILLDYCPGNHNIYLKNYTWVKSYLLEKIKEHEESLDVSNPRDFIDYFLIERNQENA
                     NQWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRH
                     RSPSMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHDVTCDTKFRNYFIPKGTAVLTSLT
                     SVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFIPFSAGKRMCLGESLARMELFLFLT
                     TILQNFKLKSLVDPKDINTTPICSSLSSVPPTFQMRFIPL"
     exon            180..342
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            343..492
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            493..653
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            654..830
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            831..972
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1160
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..1302
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..1721
                     /gene="Cyp2c13"
                     /gene_synonym="Cyp2c38"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagggtctc catggatcca gttgtggtct tgttgctcag tctgttcttt ctgcttttcc
       61 tgtctctatg gagactgagc tctgggagag ggaaactccc tcctggccca actcctctcc
      121 caattattgg aaatttcttt caggttgata tgaaggacat tcggcaatcc ttaaccaatt
      181 tttctaaaac ctatggacct gtgtatactc tgtatgttgg ctcacagcct actgtggtat
      241 tgcatggcta tgaggcattg aaagaagctc ttgttgatca tggggaagaa ttctctggaa
      301 gaggaaggtt accaatttgt gaaaaggttg ctaaaggaca gggcattgct tttagccatg
      361 gaaatgtatg gaaagccaca aggcatttca cagtcaaaac cctgaggaat ttgggcatgg
      421 gaaaagggac cattgaagac aaagtgcaag aggaagcaaa gtggctagtg aaagaactga
      481 agaaaaccaa tggctcaccc tgtgatcccc aattcatcat gggatgtgct cctggcaatg
      541 tcatctgctg cattatcttg cagaatcgtt ttgattatga agataaggat tttcttaact
      601 tgatagaaaa agtgaatgag gccgttaaaa ttataagctc tcctgggatt caggttttca
      661 atatatttcc tatacttctt gattattgtc cgggaaatca taacatatat ttaaaaaatt
      721 atacatgggt taagagttac cttttggaga aaataaaaga acatgaagaa tcgttggatg
      781 tttcaaatcc tcgggacttc attgattatt ttctaattga aagaaatcag gaaaatgcca
      841 atcagtggat gaactataca cttgaacacc tggcaatcat ggtgactgat ttgttttttg
      901 ctggaataga gacagtaagc tcaacaatga gatttgctct cctgctcttg atgaagtacc
      961 cacacgtcac agctaaagtc caggaagaga ttgaccatgt gattgggaga caccgcagcc
     1021 cctctatgca ggacaggagc cacatgccct acacaaatgc catggtccac gaggttcaga
     1081 gatacattga cattggtcca aatggtctgc ttcatgatgt gacctgtgac actaaattca
     1141 gaaactactt cataccgaag ggaacagcag tactaacatc acttacatca gtgctgcatg
     1201 acagcaagga gtttcccaac ccagagatgt ttgacccagg tcactttcta gatgagaatg
     1261 gaaactttaa gaaaagtgac tacttcattc ctttctcagc aggaaaacgg atgtgtttgg
     1321 gagagagcct ggcccgcatg gagctgtttc tattcctgac aaccatttta cagaatttca
     1381 aactaaaatc tctggttgac ccaaaggaca tcaatacaac cccaatatgt tcttcacttt
     1441 cttcagttcc tcccactttc cagatgcgct tcatccctct ctaatgaaaa ccagaaaaca
     1501 gaaatgaaga tgaggaaaga tcctgctgtt ttgttttctg aaggtaccca cagaagcctt
     1561 catttactac tgtcatagaa atgccactgt atccttcctt cttctcacag cttcggttct
     1621 ctatttgtcc aaggataata gttctgcatt atatagttcc taaactcaat gtaaaagatc
     1681 ctgataaaga agccacttca aataaaagag ttctactgtg a
//
