LOCUS       NM_020091               1257 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus chymosin (Cym), mRNA.
ACCESSION   NM_020091
VERSION     NM_020091.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Kageyama,T., Ichinose,M., Tsukada-Kato,S., Omata,M., Narita,Y.,
            Moriyama,A. and Yonezawa,S.
  TITLE     Molecular cloning of neonate/infant-specific pepsinogens from rat
            stomach mucosa and their expressional change during development
  JOURNAL   Biochem Biophys Res Commun 267 (3), 806-812 (2000)
   PUBMED   10673373
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Nov 26, 2020 this sequence version replaced NM_020091.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ251688.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN16676806
                                           [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-72                JAXUCZ010000002.1  197527236-197527307 c
            73-223              JAXUCZ010000002.1  197525173-197525323 c
            224-341             JAXUCZ010000002.1  197524177-197524294 c
            342-460             JAXUCZ010000002.1  197523681-197523799 c
            461-660             JAXUCZ010000002.1  197521551-197521750 c
            661-774             JAXUCZ010000002.1  197519844-197519957 c
            775-919             JAXUCZ010000002.1  197518962-197519106 c
            920-1018            JAXUCZ010000002.1  197518329-197518427 c
            1019-1257           JAXUCZ010000002.1  197516950-197517188 c
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1257
                     /gene="Cym"
                     /note="chymosin"
                     /db_xref="GeneID:56825"
                     /db_xref="RGD:708486"
     exon            1..72
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     CDS             11..1150
                     /gene="Cym"
                     /EC_number="3.4.23.4"
                     /note="embryonic pepsinogen; prochymosin"
                     /codon_start=1
                     /product="embryonic pepsinogen precursor"
                     /protein_id="NP_064476.2"
                     /db_xref="GeneID:56825"
                     /db_xref="RGD:708486"
                     /translation="MRCFVLLLAVLAIAQSHVVTRIPLHKGKSLRNTLKEQGLLEDFL
                     RRHQYEFSEKNSNIGVVASEPLTNYLDSEYFGLIYVGTPPQEFKVVFDTGSSELWVPS
                     VYCSSKVCRNHNRFDPSKSFTFQNLSKPLFVQYGTGSVEGFLAYDTVTVSDIVVPHQT
                     VGLSTEEPGDIFTYSPFDGILGLAYPTFASKYSVPIFDNMMNRHLVAQDLFSVYMSRN
                     DQGSMLTLGAIDQSYFIGSLHWVPVTVQGYWQFTVDRITINDEVVACQGGCPAVLDTG
                     TALLTGPGRDILNIQHAIGAVQGQHDQFDIDCWRLNFMPTVVFEINGREFPLPPSAYT
                     NQFQGSCSSGFRHGSQMWILGDVFIREFYSVFDRANNRVGLAKAI"
     exon            73..223
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            224..341
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            342..460
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            461..660
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            661..774
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            775..919
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1018
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
     exon            1019..1257
                     /gene="Cym"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtggtccaga atgaggtgct ttgtgctgct cctcgcggtt cttgccatcg cccagagcca
       61 tgtggtcacc aggatccctc tgcacaaagg gaagtctctg aggaacaccc tgaaggagca
      121 aggactgctg gaggactttc tgaggagaca ccagtatgag ttcagtgaga agaactccaa
      181 catcggggtg gtggccagtg agcctctgac caactatcta gatagtgagt acttcggact
      241 gatctacgtt ggaacaccac cccaggagtt caaggtggtg tttgacacag gctcctcaga
      301 actctgggtg ccctctgtgt actgcagcag caaagtttgc agaaaccaca accgctttga
      361 cccatccaag tccttcacct tccagaacct gagcaagccc ctgtttgtcc agtatggtac
      421 tggcagtgtg gagggcttcc tggcctatga cactgtcacg gtctctgaca ttgtagttcc
      481 ccatcagact gtgggcctga gtactgagga accaggtgac atcttcacct actctccatt
      541 tgatggcatc ctgggcctgg cctaccctac ttttgcctcc aagtactcag tacccatatt
      601 tgacaacatg atgaacaggc acctggtggc ccaagacctg ttctccgttt acatgagcag
      661 gaatgaccaa gggagcatgc tcacgctggg ggccatcgat cagtcctact tcataggctc
      721 actgcactgg gtgcctgtga ctgtacaagg atattggcag ttcacagtgg acaggatcac
      781 aatcaatgat gaggtggtgg cttgtcaagg tggctgccct gctgttctgg acacaggcac
      841 tgccctgctg acagggcctg gtagagacat cctcaatatt cagcacgcca ttggagctgt
      901 gcagggccaa catgaccagt ttgacattga ctgctggagg ctgaacttca tgcccacggt
      961 tgtctttgag atcaatggta gggagttccc actgccaccc tctgcctata ccaaccagtt
     1021 ccagggctcc tgctccagtg gcttcaggca tggctcccag atgtggatcc ttggagatgt
     1081 gttcattcgg gagttctaca gtgtgtttga cagggccaac aatcgtgtcg gactggccaa
     1141 ggctatctga ttatacaacc acacacacac acacacacac acacacacac acacacacac
     1201 acacacacac acacgattta tcaagtggaa cgctcccaat aaatactgca tttctcc
//
