LOCUS       NM_001277194            1195 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cytochrome c-1 (Cyc1), mRNA.
ACCESSION   NM_001277194
VERSION     NM_001277194.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Guo,R., Zong,S., Wu,M., Gu,J. and Yang,M.
  TITLE     Architecture of Human Mitochondrial Respiratory Megacomplex
            I2III2IV2
  JOURNAL   Cell 170 (6), 1247-1257 (2017)
   PUBMED   28844695
REFERENCE   2  (bases 1 to 1195)
  AUTHORS   Kuang,E., Okumura,C.Y., Sheffy-Levin,S., Varsano,T., Shu,V.C.,
            Qi,J., Niesman,I.R., Yang,H.J., Lopez-Otin,C., Yang,W.Y.,
            Reed,J.C., Broday,L., Nizet,V. and Ronai,Z.A.
  TITLE     Regulation of ATG4B stability by RNF5 limits basal levels of
            autophagy and influences susceptibility to bacterial infection
  JOURNAL   PLoS Genet 8 (10), e1003007 (2012)
   PUBMED   23093945
  REMARK    Erratum:[PLoS Genet. 2020 May 11;16(5):e1008795. PMID: 32392217]
REFERENCE   3  (bases 1 to 1195)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   4  (bases 1 to 1195)
  AUTHORS   Zhao,X., Leon,I.R., Bak,S., Mogensen,M., Wrzesinski,K., Hojlund,K.
            and Jensen,O.N.
  TITLE     Phosphoproteome analysis of functional mitochondria isolated from
            resting human muscle reveals extensive phosphorylation of inner
            membrane protein complexes and enzymes
  JOURNAL   Mol Cell Proteomics 10 (1), M110.000299 (2011)
   PUBMED   20833797
REFERENCE   5  (bases 1 to 1195)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   6  (bases 1 to 1195)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   7  (bases 1 to 1195)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   8  (bases 1 to 1195)
  AUTHORS   Halestrap,A.P.
  TITLE     Stimulation of the respiratory chain of rat liver mitochondria
            between cytochrome c1 and cytochrome c by glucagon treatment of
            rats
  JOURNAL   Biochem J 172 (3), 399-405 (1978)
   PUBMED   210759
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1, FN801980.1 and FM122421.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ224965.1, FQ220496.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-35                JAXUCZ010000007.1  109947765-109947799
            36-660              FN801980.1         1-625
            661-661             FM122421.1         186-186
            662-736             FN801980.1         627-701
            737-1049            FM122421.1         262-574
            1050-1195           JAXUCZ010000007.1  109949997-109950142
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..1195
                     /gene="Cyc1"
                     /note="cytochrome c-1"
                     /db_xref="GeneID:300047"
                     /db_xref="RGD:1306597"
     exon            1..166
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             35..1015
                     /gene="Cyc1"
                     /codon_start=1
                     /product="cytochrome c-1"
                     /protein_id="NP_001264123.1"
                     /db_xref="GeneID:300047"
                     /db_xref="RGD:1306597"
                     /translation="MAAAAAASLRRSVLGPRGMGLPGASAPGLLGGARPRHLPLRTPQ
                     AVSLSSKSGPSRGRKVMLSALGMLAAGGAGLAVALHSAVSASDLELHPPSYPWSHRGL
                     LSSLDHTSIRRGFQVYKQVCSSCHSMDYVAYRHLVGVCYTEEEAKALAEEVEVQDGPN
                     EDGNMFMRPGKLSDYFPKPYPNPEAARAANNGALPPDLSYIVRARHGGEDYVFSLLTG
                     YCEPPTGVSLREGLYFNPYFPGQAIGMAPPIYTEVLEYDDGTPATMSQVAKDVATFLR
                     WASEPEHDHRKRMGLKMLLMMGLLLPLTYAMKRHKWSVLKSRKLAYRPPK"
     exon            167..363
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     exon            364..490
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     exon            491..648
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..809
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     exon            810..910
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
     exon            911..1195
                     /gene="Cyc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgggaacg gcggccgcac taaagagggc cgacatggcg gcggcggcgg cggcttcgct
       61 tcgccgatcg gtgctaggcc cgcggggcat ggggcttcca ggtgcaagtg ctccgggcct
      121 gctgggcggc gcgcggcccc ggcatcttcc attacggaca ccgcaggcag tgtccttgtc
      181 ctcgaagtct ggcccttctc gaggccgaaa ggtgatgctg tcagcgttgg gcatgctggc
      241 agcagggggt gcagggctag ctgtggccct tcattcggcg gtgagtgcca gtgacctgga
      301 gctgcacccc cccagctacc catggtctca ccgtggcctc ctctcctcct tggaccacac
      361 cagcattcgt aggggtttcc aggtatacaa gcaggtgtgc tcttcctgcc acagcatgga
      421 ttatgtggct taccgccacc tggtgggagt gtgctacacg gaggaagaag ctaaggcgct
      481 ggctgaggag gtggaggtcc aggatggccc taatgaggat gggaatatgt tcatgcggcc
      541 agggaagctg tctgactatt ttccaaaacc ataccccaac cctgaggctg caagagctgc
      601 taacaatgga gctttacccc ctgacctcag ctacatcgtt cgagcaaggc acggtggtga
      661 ggactatgtg ttttccttgc tcactggcta ctgtgaacct cccactgggg tgtcattgcg
      721 agaaggcctc tatttcaacc cttactttcc tggccaggcc attggcatgg ctcctcccat
      781 ctacacagaa gtcttggagt atgacgatgg taccccagct accatgtcac aagtagccaa
      841 ggatgttgcc accttccttc gctgggcatc agagccagag catgaccatc gaaaacgcat
      901 gggactcaag atgttgttga tgatgggctt gctgctgccc ctgacctatg ccatgaagcg
      961 gcataagtgg tcagtcctga agagtcgaaa gctggcttat cggccaccca agtgaccctg
     1021 ttcagtatct gcttgtcatc ttgcctgaac aagctctcag cagaccagga acagtccgag
     1081 gcctttcagg cctggcccct tttcatcaga taccagggcc aggagaccag actcttgctt
     1141 ctgatcttcc tttagccttc attgtgggaa taaattaagt ttctcaacac acaca
//
