LOCUS       NM_001034959            2428 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus cytochrome b-245 chaperone 1 (Cybc1), mRNA.
ACCESSION   NM_001034959
VERSION     NM_001034959.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2428)
  AUTHORS   Thomas,D.C., Clare,S., Sowerby,J.M., Pardo,M., Juss,J.K.,
            Goulding,D.A., van der Weyden,L., Storisteanu,D., Prakash,A.,
            Espeli,M., Flint,S., Lee,J.C., Hoenderdos,K., Kane,L., Harcourt,K.,
            Mukhopadhyay,S., Umrania,Y., Antrobus,R., Nathan,J.A., Adams,D.J.,
            Bateman,A., Choudhary,J.S., Lyons,P.A., Condliffe,A.M.,
            Chilvers,E.R., Dougan,G. and Smith,K.G.
  TITLE     Eros is a novel transmembrane protein that controls the phagocyte
            respiratory burst and is essential for innate immunity
  JOURNAL   J Exp Med 214 (4), 1111-1128 (2017)
   PUBMED   28351984
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC079126.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079126.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2428
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.3"
     gene            1..2428
                     /gene="Cybc1"
                     /note="cytochrome b-245 chaperone 1"
                     /db_xref="GeneID:619574"
                     /db_xref="RGD:1562022"
     exon            1..213
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     exon            214..365
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             281..844
                     /gene="Cybc1"
                     /note="uncharacterized protein C17orf62 homolog; eros;
                     essential for reactive oxygen species protein"
                     /codon_start=1
                     /product="cytochrome b-245 chaperone 1"
                     /protein_id="NP_001030131.1"
                     /db_xref="GeneID:619574"
                     /db_xref="RGD:1562022"
                     /translation="MYMQVETRTSTRLHLKRAPGIRSWSLLVGILSTGLAAAYYSGDS
                     LGWKLFYVTGCLFVAVQNLEDWEEAIFNKSTGKVILKTFSLYKKLLTLLRAGHDQVVV
                     LLKDIQDVNVEEEKVRYFGKGYMVVLRFATGFSHPLTQSAVMGRRSDVEAIAKLITSF
                     LELHRLESPSERSQSSDSEPDGPGGQS"
     exon            366..407
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     exon            408..481
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     exon            482..578
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     exon            579..723
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
     exon            724..2396
                     /gene="Cybc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcgcactaat tgtcgtacac gttcctcggt tctggcaaac gtgcgtgtcc tgcagctttt
       61 ctggttccga tccgttgtgt cctgtgcagg tcaccgcttg cggatctgga tcgggcgcaa
      121 ggcagattga gcaaaccgag cgtgtgcact cctcaggagg agccagcgga acggccgctt
      181 gtggagcttg ttggtaactg aagccagagg gagtggttgc aggcttcggg tgtgtttttc
      241 caagcctggt cggctgtgca gtggagccca ggttccaggg atgtatatgc aggtggaaac
      301 acgtaccagc acccgcctcc atctgaagag ggctcccggc atccggtctt ggtccctgct
      361 agttggaata ttatccactg gcctggctgc tgcctattac agtggagata gtctgggctg
      421 gaagctcttc tatgtcacag gctgcctctt tgtggctgta cagaacttgg aggactggga
      481 ggaggccatt ttcaacaaga gcactgggaa ggtcatctta aaaacattca gcctctacaa
      541 gaagctgctg actcttctca gagcgggcca tgatcaagtg gtggtcctgt tgaaagacat
      601 ccaggatgtg aatgtggagg aggaaaaggt ccgttacttt gggaagggct acatggtggt
      661 gctccggttt gcaacaggct tctcccaccc ccttactcag agtgcagtca tgggccgacg
      721 cagtgacgtg gaagccattg ccaaactcat cactagcttc ttggagctgc accgcctgga
      781 gagcccctca gaacggtcac aaagcagtga cagtgaacct gatggccctg gtggccagag
      841 ctgacagtgt ggaatggctg ctggtgaatg tcacccactt ccgatgcgtc tccgactgac
      901 ttgccaatta taagggtaca ggcagacctt ggacacccgc ctatggctcc ttgggcagtc
      961 ctactacaga ctacccgcct tttgcttgtt tacgcttcta cactttgcag aaccatgggc
     1021 taggcctctc ccacaaccca gaaaggctgc atctgtcagg atgcaggggg tggatgctac
     1081 atccagggga gggcgaggtc tcagaagtta gtgccttccc cgtggccgct ctgggttggg
     1141 cagcacagcc gggtctgcat aagctcgccc aagggcagtc tgaagtataa gatgccaagc
     1201 tttcttcagc ataagcctag tgcctgcctt caagatgcct tgccacccca ggatattgta
     1261 ggcaagactc cacttcatag tgagagtgag acacccacac gcaggtagga aggacccact
     1321 cctgtaaaca ctgatgttta ctctccctga ccatccctca agatggacac ccttggtggt
     1381 caggagcttc cctgaaggca actatggatg ctgaatgcct ggccacagaa ctctcagaga
     1441 aatcagagtg ttgctgacta ccctgttcct tctcagacaa ctttgtctga gatcccagca
     1501 ctgttgtagc acagcaggaa tggaaggctc tcccaaccca accagggaag aagctgctac
     1561 tggaggaaag gtcacctctt ttggtttttg gcatcctgct gtctttaaga cctgggagct
     1621 cctttacaga aactgagtct tagcctttca agccttgaaa agacctgaag aaaataggca
     1681 tgtggagaca cagccctgtc aatcccagtg ttcagaagtg gggcgggaag aaagttcaag
     1741 gccagcctgg gccatggcct cttctaataa agttggtacc aaccacttac ggtccttttc
     1801 tgctcttcta gtttccttct gagtcgactc aagtccctca aaagtacact gtttactaag
     1861 tttccagcta gaagctgtgg atctctggtc tacacagagc tcctccaagc cgtataccca
     1921 tacctcatca ggtagacctg ggaaatagaa gagttacata gacaaagaag ttaaggcagc
     1981 cctgaggcta ctgcccctag gctgagcaca gtagttaggc aagaactatg aacaggtctt
     2041 ctgaggtgac tgctactagt cccaacttgg gaacatggtc ccttgaacat gctaaagtga
     2101 gctttctaaa tggttaagtt agagattttt ctccccagat gaaatgtgaa atatagcttg
     2161 ttggtttttg gcttgttgcc cacagactct taaggtactt tagacaagag aaggaggagt
     2221 ctgtctctta ggtgctgtca tatccccttc caatattgcc cagtgctgag actcattcct
     2281 tggtgaaggc atgaaattct ctatggtggt aaaaagttga tccaagtttc tgttggtggg
     2341 acttccactt cctggtcttt ttatttcaga agtaataaag ctctacgtgc aaattaaaaa
     2401 aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
