LOCUS       NM_001007628            2081 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus CXXC finger protein 5 (Cxxc5), mRNA.
ACCESSION   NM_001007628 XM_214577
VERSION     NM_001007628.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2081)
  AUTHORS   Xu,C., Liu,K., Lei,M., Yang,A., Li,Y., Hughes,T.R. and Min,J.
  TITLE     DNA Sequence Recognition of Human CXXC Domains and Their Structural
            Determinants
  JOURNAL   Structure 26 (1), 85-95 (2018)
   PUBMED   29276034
REFERENCE   2  (bases 1 to 2081)
  AUTHORS   Aras,S., Pak,O., Sommer,N., Finley,R. Jr., Huttemann,M.,
            Weissmann,N. and Grossman,L.I.
  TITLE     Oxygen-dependent expression of cytochrome c oxidase subunit 4-2
            gene expression is mediated by transcription factors RBPJ, CXXC5
            and CHCHD2
  JOURNAL   Nucleic Acids Res 41 (4), 2255-2266 (2013)
   PUBMED   23303788
REFERENCE   3  (bases 1 to 2081)
  AUTHORS   Andersson,T., Sodersten,E., Duckworth,J.K., Cascante,A., Fritz,N.,
            Sacchetti,P., Cervenka,I., Bryja,V. and Hermanson,O.
  TITLE     CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in
            neural stem cells
  JOURNAL   J Biol Chem 284 (6), 3672-3681 (2009)
   PUBMED   19001364
  REMARK    GeneRIF: CXXC5 expression overlapped with BMP4 adjacent to Wnt3a
            expression in the dorsal regions of the telencephalon, including
            the developing choroid plexus.
REFERENCE   4  (bases 1 to 2081)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083622.1, DV723039.1 and BE114271.1.
            
            On Oct 13, 2007 this sequence version replaced NM_001007628.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CK365729.1, BP482957.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1226              BC083622.1         1-1226
            1227-1779           DV723039.1         110-662
            1780-2081           BE114271.1         1-302               c
FEATURES             Location/Qualifiers
     source          1..2081
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p11"
     gene            1..2081
                     /gene="Cxxc5"
                     /note="CXXC finger protein 5"
                     /db_xref="GeneID:291670"
                     /db_xref="RGD:1359466"
     exon            1..1042
                     /gene="Cxxc5"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..1087
                     /gene="Cxxc5"
                     /note="CXXC finger 5"
                     /codon_start=1
                     /product="CXXC-type zinc finger protein 5"
                     /protein_id="NP_001007629.1"
                     /db_xref="GeneID:291670"
                     /db_xref="RGD:1359466"
                     /translation="MSSLGGGSQDAGGSSSSSNTSSSSGSGQKAGGTDKSATVAATAP
                     ASVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGAGSMMGGESADKAA
                     AAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFA
                     QSTEMLKRVVQEHLPLMSEAGAGLPDMEAVAGAEALNGQSDFPYLGAFPINPGLFIMT
                     PAGVFLAESALHMAGLAEYPMQGELASAISSGKKKRKRCGMCAPCRRRINCEQCSSCR
                     NRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ"
     exon            1043..2065
                     /gene="Cxxc5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cctgatcatg cgcctaccct gagtgaggcc ctccaggcat ctgtattgtg ggcagccggg
       61 ctacacgctc aactctgagc ccccagcagc agtttgcagg ctctcccagc agcggggtct
      121 gggcctcggc cccaccatgt cgagcctcgg cggtggctcc caggacgccg gtggcagtag
      181 cagcagcagt aacaccagta gcagcagtgg cagtggccaa aaggcaggag gaacagacaa
      241 aagtgccacg gtggctgcca cggcaccggc ctccgtggca gacgatgccc cgccccctga
      301 gcgtcggaac aagagtggaa tcatcagtga acccctcaac aagagcctgc gtcgctcccg
      361 cccactctct cactactcct cctttggtag cagtggtggc gccggaagca tgatgggagg
      421 ggagtctgct gacaaggctg ccgcagccgc agcctcccta ttggccaacg gtcatgacct
      481 ggctgcggcc atggcggtgg acaaaagcaa ccctacctca aagcacaaaa gtggtgctgt
      541 ggccagcctg ctaagcaagg cagagcgggc cacagagctg gcagccgagg gacagctgac
      601 actgcagcag ttcgcacagt ccacggagat gctaaagcga gtggtgcagg aacacctgcc
      661 actgatgagc gaggcgggtg ccggcctgcc cgacatggag gctgtggccg gcgccgaagc
      721 cctcaatggc cagtccgact tcccttacct gggcgctttc cccatcaatc caggcctctt
      781 catcatgacc ccagccggtg tgttcctggc tgagagtgcg ctgcacatgg ctggcctggc
      841 cgagtacccc atgcagggag agctggcttc tgccatcagc tcgggcaaga agaagcggaa
      901 acgctgcggc atgtgtgcgc cctgccggcg gcgcatcaac tgcgagcagt gcagcagttg
      961 taggaaccga aagactggcc atcagatttg caaattcaga aagtgtgaag aactcaaaaa
     1021 gaagccttcc gctgctctgg agaaggtgat gcttccgtcg ggagctgcct tccggtggtt
     1081 tcagtgattt cagtgacggc cgggaaccca aagctgccct ctccgtgcaa tgtcacagcc
     1141 cgcgtggtct ccggcaaggg attcgggcga agacaaacgg atgcacccgt ctttagaacc
     1201 aaaaatattc tctcacagat ttcattcctg tttttatata tatatatttt ttgttgtcgt
     1261 tttaacatct ccacgtccct agtataaaaa gaaaaagaaa aaaaatttaa ctgctttttc
     1321 agaagaacat caacaaacaa caagagaggt aaagacgaat ctataaagta ccgagacttc
     1381 ctgggcaaag aatggacaat cagtctcctt cctgtgtcaa tgtcaatgtt gtctgtgcgg
     1441 gagatgctgt ttttgtgtag agaatgtaaa ttttctgtaa ccttttgcaa tctagttact
     1501 aataagcact actgtaattt agcacagttt taactccact ctgattttaa cttcctttga
     1561 ttctttccaa ccatgaaata gtgcatagtt tgcctggaga atccactcac gtttataaag
     1621 gaaatgttga tcgcaccgtg tagaagcccc ctctgtatcc gttcacgtgt gcagagcggc
     1681 cagagcccac tgggactggg agttcctgac ccaggcccga ccatgtcgca cccatcgtcc
     1741 cctgactggg acgcccccgc cccaacagtg acggattttt ggagagatga aaattctatt
     1801 catttgttga tccgctgaga tctggggagc ccacatctca gtatttctga tcctggctac
     1861 ttcccctaga aaaaatgagc cctctttttc cagccttgct cacagcagca gaagaaaggg
     1921 cttcttttcg tggtcccctg ctggtagggg tgggtgccca ggggccccct gcccgtggcc
     1981 agctccctgc tgaggaacat gctgtttgta ttgttttagg agaccaggct gttttgtgaa
     2041 taaaactgaa tgcatgtttg tgtcaaaaaa aaaaaaaaaa a
//
