LOCUS       NM_001013137            1620 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Rattus norvegicus C-X-C motif chemokine ligand 14 (Cxcl14), mRNA.
ACCESSION   NM_001013137 XM_225162
VERSION     NM_001013137.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1620)
  AUTHORS   Ma,R., Li,Y., Dong,X., Zhang,Y., Chen,X., Zhang,Y., Zou,H. and
            Wang,Y.
  TITLE     PAX6/CXCL14 regulatory axis promotes the repair of corneal injury
            by enhancing corneal epithelial cell proliferation
  JOURNAL   J Transl Med 22 (1), 458 (2024)
   PUBMED   38750454
  REMARK    GeneRIF: PAX6/CXCL14 regulatory axis promotes the repair of corneal
            injury by enhancing corneal epithelial cell proliferation.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1620)
  AUTHORS   Liu,M., Zhang,S.B., Luo,Y.X., Yang,Y.L., Zhang,X.Z., Li,B.,
            Meng,Y., Chen,Y.J., Guo,R.X., Xiong,Y.C., Xin,W.J. and Li,D.
  TITLE     NFATc2-dependent epigenetic upregulation of CXCL14 is involved in
            the development of neuropathic pain induced by paclitaxel
  JOURNAL   J Neuroinflammation 17 (1), 310 (2020)
   PUBMED   33070779
  REMARK    GeneRIF: NFATc2-dependent epigenetic upregulation of CXCL14 is
            involved in the development of neuropathic pain induced by
            paclitaxel.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1620)
  AUTHORS   Zeng,L., Gu,N., Chen,J., Jin,G. and Zheng,Y.
  TITLE     IRX1 hypermethylation promotes heart failure by inhibiting CXCL14
            expression
  JOURNAL   Cell Cycle 18 (23), 3251-3262 (2019)
   PUBMED   31640472
  REMARK    GeneRIF: IRX1 hypermethylation promotes heart failure by inhibiting
            CXCL14 expression.
REFERENCE   4  (bases 1 to 1620)
  AUTHORS   Ge,Y., Waldemer,R.J., Nalluri,R., Nuzzi,P.D. and Chen,J.
  TITLE     RNAi screen reveals potentially novel roles of cytokines in
            myoblast differentiation
  JOURNAL   PLoS One 8 (7), e68068 (2013)
   PUBMED   23844157
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1620)
  AUTHORS   Cao,Q., Chen,H., Deng,Z., Yue,J., Chen,Q., Cao,Y., Ning,L., Lei,X.
            and Duan,E.
  TITLE     Genetic deletion of Cxcl14 in mice alters uterine NK cells
  JOURNAL   Biochem Biophys Res Commun 435 (4), 664-670 (2013)
   PUBMED   23688424
REFERENCE   6  (bases 1 to 1620)
  AUTHORS   Yoo,H.I., Kang,J.H., Yang,S.Y., Yong,J.H., Moon,J.S., Kim,M.S.,
            Jung,J.Y., Koh,J.T., Kim,W.J., Oh,W.M., Lee,E.J. and Kim,S.H.
  TITLE     Differential expression of cxcl-14 during eruptive movement of rat
            molar germs
  JOURNAL   J Exp Zool B Mol Dev Evol 316 (6), 418-426 (2011)
   PUBMED   21462317
  REMARK    GeneRIF: Differential expression of cxcl-14 during eruptive
            movement of rat molar germs
REFERENCE   7  (bases 1 to 1620)
  AUTHORS   Lu,C.C., Appler,J.M., Houseman,E.A. and Goodrich,L.V.
  TITLE     Developmental profiling of spiral ganglion neurons reveals insights
            into auditory circuit assembly
  JOURNAL   J Neurosci 31 (30), 10903-10918 (2011)
   PUBMED   21795542
REFERENCE   8  (bases 1 to 1620)
  AUTHORS   Yamamoto,T., Yamashita,A., Yamada,K. and Hata,R.
  TITLE     Immunohistochemical localization of chemokine CXCL14 in rat
            hypothalamic neurons
  JOURNAL   Neurosci Lett 487 (3), 335-340 (2011)
   PUBMED   20974226
  REMARK    GeneRIF: These results demonstrated for the first time that CXCL14
            protein is present in a subset of hypothalamic neurons
REFERENCE   9  (bases 1 to 1620)
  AUTHORS   Maerki,C., Meuter,S., Liebi,M., Muhlemann,K., Frederick,M.J.,
            Yawalkar,N., Moser,B. and Wolf,M.
  TITLE     Potent and broad-spectrum antimicrobial activity of CXCL14 suggests
            an immediate role in skin infections
  JOURNAL   J Immunol 182 (1), 507-514 (2009)
   PUBMED   19109182
REFERENCE   10 (bases 1 to 1620)
  AUTHORS   Yang,D., Chen,Q., Hoover,D.M., Staley,P., Tucker,K.D., Lubkowski,J.
            and Oppenheim,J.J.
  TITLE     Many chemokines including CCL20/MIP-3alpha display antimicrobial
            activity
  JOURNAL   J Leukoc Biol 74 (3), 448-455 (2003)
   PUBMED   12949249
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On May 27, 2021 this sequence version replaced NM_001013137.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101896.1, DN936204.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-267               JAXUCZ010000017.1  8323150-8323416
            268-373             JAXUCZ010000017.1  8323575-8323680
            374-487             JAXUCZ010000017.1  8327177-8327290
            488-1620            JAXUCZ010000017.1  8330044-8331176
FEATURES             Location/Qualifiers
     source          1..1620
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..1620
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /note="C-X-C motif chemokine ligand 14"
                     /db_xref="GeneID:306748"
                     /db_xref="RGD:1307406"
     exon            1..267
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /inference="alignment:Splign:2.1.0"
     CDS             204..503
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /note="C-X-C motif chemokine 14; chemokine (C-X-C motif)
                     ligand 14"
                     /codon_start=1
                     /product="C-X-C motif chemokine 14 precursor"
                     /protein_id="NP_001013155.1"
                     /db_xref="GeneID:306748"
                     /db_xref="RGD:1307406"
                     /translation="MRLLAAALLLLLLALCASRVDGSKCKCSRKGPKIRYSDVKKLEM
                     KPKYPHCEEKMVIITTKSMSRYRGQEHCLHPKLQSTKRFIKWYNAWNEKRRVYEE"
     exon            268..373
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /inference="alignment:Splign:2.1.0"
     exon            374..487
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /inference="alignment:Splign:2.1.0"
     exon            488..1620
                     /gene="Cxcl14"
                     /gene_synonym="BRAK"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gatcgcagca cccagcgcca agcgcagcgc agcaccgcga cagacggcag gagcacccat
       61 cgacgggcgc agctggagag agcccagcat agagaggcgg gctcaaaacc gagaaccctg
      121 ccgggcggca tcccccggcc gccgcacgca caggccggcg ccctcctcgc ctccctgctc
      181 cccaccgcgc ccctccggcc agcatgaggc tcctggcggc cgcgctgctc ctgctgctcc
      241 tggcgctgtg cgcctcgcgc gtggacgggt ccaagtgtaa gtgttcccgg aaggggccca
      301 agatccgcta cagcgacgtg aagaagctgg aaatgaagcc aaagtaccca cactgcgagg
      361 agaagatggt tatcataacc accaagagca tgtccaggta ccgcggccag gagcactgcc
      421 tgcatcctaa gctgcaaagt accaagcgct tcatcaaatg gtacaacgcc tggaacgaga
      481 aacgcagggt ctacgaagag tagggtggac gatcttggaa agaaaacctc caggccagtt
      541 gagagacttc agcagaggac tttgcagatt aaaaataaaa gccctttctt tctcacaagc
      601 ataagacaaa ttatatattg ctgtgaagct cttcttacca gggtcagttt ttacatttta
      661 tagctgtgtg cgaaagcctt ccagatgtga gatccagctc tcctgcgtac cagacttcat
      721 tacaagtggc tttttgccgg gggttggggg gttgggggtg ggcccaagcc tttccttttt
      781 aaaataaggg tttttgtatt tgtccatatg tcaccacaca tctgaacttt ataagcgcct
      841 ggaaggagca atcagtatgg ttcaggcaat tcattgcact gttgctccgg tccaggcttt
      901 cgaagcttcc cctcagagag cctggcgcct cagcacagct gccacaggct ctcctgggct
      961 tatgactggt caagagtttc ggtgtggctc caccatggcc cctgttgcag ggcaattggg
     1021 aacaagtcct tctgcatctg tgcctagagg aactcaatct acttcccagg acgagcttca
     1081 tgcccccacc ccagccccac ccccacccca gctcattccc ctatcccaac caggcaagcg
     1141 atccttaaag gagctgggtc tttctctcga aacctctgag ggtttctgaa aggctcactg
     1201 ctttggtaga tgatgcttct gaagcatcag aagcccccgg cagcgtgaga aaactgtgtg
     1261 gaggaaaagg ggaaaattca ggactcaatg catgacatcc agccagagct acacatccta
     1321 ctggcatggg gagacccacg tagctctgtt cccctcgccc ccacagaaag cgcactcccc
     1381 cttcggtgca tatgcaaaca gcgaggtcct cttttggagt taggatgacc ctgcaccctc
     1441 tcctgtgtac atattgcttc agtacccgcc cctgccacac gctgcccctc agtagaggcc
     1501 gcactggacg gctgtgaatc tgctatgtaa gtgctgagat tcatgagtgc tgcatgcggg
     1561 tttcatgttc tttctaagat gaaaaagaaa gtaataaaaa tatatttgaa gttaccaaaa
//
