LOCUS       NM_001419199            1118 bp    mRNA    linear   ROD 23-JUL-2024
DEFINITION  Rattus norvegicus C-X-C motif chemokine ligand 13 (Cxcl13),
            transcript variant 1, mRNA.
ACCESSION   NM_001419199 XM_006250710
VERSION     NM_001419199.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1118)
  AUTHORS   Yi,H., Zhu,B., Zheng,C., Ying,Z. and Cheng,M.
  TITLE     CXCL13/CXCR5 promote chronic postsurgical pain and astrocyte
            activation in rats by targeting NLRP3
  JOURNAL   Neuroreport 35 (6), 406-412 (2024)
   PUBMED   38526919
  REMARK    GeneRIF: CXCL13/CXCR5 promote chronic postsurgical pain and
            astrocyte activation in rats by targeting NLRP3.
REFERENCE   2  (bases 1 to 1118)
  AUTHORS   Cao,J., Hu,C., Ding,Z., Chen,J., Liu,S. and Li,Q.
  TITLE     Mechanism of IRF5-regulated CXCL13/CXCR5 Signaling Axis in
            CCI-induced Neuropathic Pain in Rats
  JOURNAL   Curr Mol Med 24 (7), 940-949 (2024)
   PUBMED   37622691
  REMARK    GeneRIF: Mechanism of IRF5-regulated CXCL13/CXCR5 Signaling Axis in
            CCI-induced Neuropathic Pain in Rats.
REFERENCE   3  (bases 1 to 1118)
  AUTHORS   Chen,J., Lu,C., Wang,X., Wang,L., Chen,J. and Ji,F.
  TITLE     LncRNA NONRATT009773.2 promotes bone cancer pain progression
            through the miR-708-5p/CXCL13 axis
  JOURNAL   Eur J Neurosci 55 (3), 661-674 (2022)
   PUBMED   35075718
  REMARK    GeneRIF: LncRNA NONRATT009773.2 promotes bone cancer pain
            progression through the miR-708-5p/CXCL13 axis.
REFERENCE   4  (bases 1 to 1118)
  AUTHORS   Chen,F., Li,X., Li,Z., Zhou,Y., Qiang,Z. and Ma,H.
  TITLE     The roles of chemokine (C-X-C motif) ligand 13 in spinal cord
            ischemia-reperfusion injury in rats
  JOURNAL   Brain Res 1727, 146489 (2020)
   PUBMED   31589828
  REMARK    GeneRIF: The roles of chemokine (C-X-C motif) ligand 13 in spinal
            cord ischemia-reperfusion injury in rats.
REFERENCE   5  (bases 1 to 1118)
  AUTHORS   Zhu,M., Yuan,S.T., Yu,W.L., Jia,L.L. and Sun,Y.
  TITLE     CXCL13 regulates the trafficking of GluN2B-containing NMDA receptor
            via IL-17 in the development of remifentanil-induced hyperalgesia
            in rats
  JOURNAL   Neurosci Lett 648, 26-33 (2017)
   PUBMED   28359934
  REMARK    GeneRIF: Study highlighted the contribution of IL-17 pathway in the
            trafficking of CXCL13-induced GluN2B-containing
            N-methyl-d-aspartate receptor in the pathogenesis of
            remifentanil-induced hyperalgesia.
REFERENCE   6  (bases 1 to 1118)
  AUTHORS   Luther,S.A., Ansel,K.M. and Cyster,J.G.
  TITLE     Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7
            ligands in lymph node development
  JOURNAL   J Exp Med 197 (9), 1191-1198 (2003)
   PUBMED   12732660
REFERENCE   7  (bases 1 to 1118)
  AUTHORS   Spinetti,G., Camarda,G., Bernardini,G., Romano Di Peppe,S.,
            Capogrossi,M.C. and Napolitano,M.
  TITLE     The chemokine CXCL13 (BCA-1) inhibits FGF-2 effects on endothelial
            cells
  JOURNAL   Biochem Biophys Res Commun 289 (1), 19-24 (2001)
   PUBMED   11708770
REFERENCE   8  (bases 1 to 1118)
  AUTHORS   Jenh,C.H., Cox,M.A., Hipkin,W., Lu,T., Pugliese-Sivo,C.,
            Gonsiorek,W., Chou,C.C., Narula,S.K. and Zavodny,P.J.
  TITLE     Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist
            for the human CXCR3 receptor
  JOURNAL   Cytokine 15 (3), 113-121 (2001)
   PUBMED   11554781
REFERENCE   9  (bases 1 to 1118)
  AUTHORS   Gosling,J., Dairaghi,D.J., Wang,Y., Hanley,M., Talbot,D., Miao,Z.
            and Schall,T.J.
  TITLE     Cutting edge: identification of a novel chemokine receptor that
            binds dendritic cell- and T cell-active chemokines including ELC,
            SLC, and TECK
  JOURNAL   J Immunol 164 (6), 2851-2856 (2000)
   PUBMED   10706668
REFERENCE   10 (bases 1 to 1118)
  AUTHORS   Legler,D.F., Loetscher,M., Roos,R.S., Clark-Lewis,I., Baggiolini,M.
            and Moser,B.
  TITLE     B cell-attracting chemokine 1, a human CXC chemokine expressed in
            lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5
  JOURNAL   J Exp Med 187 (4), 655-660 (1998)
   PUBMED   9463416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            On Mar 29, 2023 this sequence version replaced XM_006250710.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.51179.1, CF110826.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676810 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-106               JAXUCZ010000014.1  13917815-13917920   c
            107-239             JAXUCZ010000014.1  13916086-13916218   c
            240-320             JAXUCZ010000014.1  13913907-13913987   c
            321-1118            JAXUCZ010000014.1  13912858-13913655   c
FEATURES             Location/Qualifiers
     source          1..1118
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1118
                     /gene="Cxcl13"
                     /note="C-X-C motif chemokine ligand 13"
                     /db_xref="GeneID:498335"
                     /db_xref="RGD:1564256"
     exon            1..106
                     /gene="Cxcl13"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..375
                     /gene="Cxcl13"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; C-X-C motif chemokine 13; chemokine (C-X-C
                     motif) ligand 13"
                     /codon_start=1
                     /product="C-X-C motif chemokine 13 isoform 1 precursor"
                     /protein_id="NP_001406128.1"
                     /db_xref="GeneID:498335"
                     /db_xref="RGD:1564256"
                     /translation="MRLCTAALLLLLAICLPPGHGILETHYTNLKCRCSKVSSTFINL
                     ILVDWIQVIRPGNGCPKTEIIFWTKAKKAICVNPTARWLPKVLKFVRSRSITSTPQAP
                     VSKKRAA"
     exon            107..239
                     /gene="Cxcl13"
                     /inference="alignment:Splign:2.1.0"
     exon            240..320
                     /gene="Cxcl13"
                     /inference="alignment:Splign:2.1.0"
     exon            321..1118
                     /gene="Cxcl13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcctagac tgagagctga agggtgaact ccacctccag gcagaatgag gctctgcacc
       61 gcagccctgc ttcttctact ggccatctgc ctccctccag gccacggtat tctggagacc
      121 cattacacaa acttgaaatg taggtgttcc aaggtgagct cgacctttat caatctaatt
      181 ctcgtagatt ggattcaagt tatacgccct gggaatggct gccccaaaac tgaaatcatt
      241 ttctggacca aggccaagaa agctatatgt gtgaatccta ctgccagatg gttaccaaaa
      301 gtattaaaat ttgtccgaag cagaagtatt acttcaactc cccaagctcc agtgagtaag
      361 aaaagagctg cctgaagcca ctgtcacccc aaaagacacc tgcacccttt cttaatccct
      421 gctcggaatc ttagtgttac gttcttagtt gaagaatttc caagaaaata acttccctct
      481 acaaacacgg ctgtagatta aaagaaaaaa atcctgcagt agctgagagg agacactcga
      541 gctccttccc atactcaacc catattcttg ttccttaagg gaggatattt tcgagcaggc
      601 atttagtgac aagccacttt ggtaatagac ctgttgttta gtgttaaact atcctagacc
      661 ctagaggaat aaaagcatac atgtcgaatc tgaacccata gctcctacta acaagaggtt
      721 tatgagatgg acttcagtta gtttgcaccc ttgcaaaaat caggcttcca gaatagtttc
      781 cagaaggtcc ctaagaagca gacgcattac cagcctaagg tgatgcagag caggtctcct
      841 ttagagagaa tcttcatgag ggaaataatg cttcgacttt gaaaggttgc ttgtacaaaa
      901 tttattgtct tggattaaaa ccagtaacac tgaaagatcc tcagcttaaa gttccaggct
      961 ccttaacagt atacaaatat attcctttgc actgtgaccc tgctaatcta tttttattat
     1021 tcacatcttt cacacagaca aaataccagt ctcttgtatc aaattcttta acgtttccta
     1081 ttcatccagt gtcattcaat aaacttaatc aaatagtt
//
