LOCUS       NM_182952               1054 bp    mRNA    linear   ROD 11-SEP-2024
DEFINITION  Rattus norvegicus C-X-C motif chemokine ligand 11 (Cxcl11), mRNA.
ACCESSION   NM_182952
VERSION     NM_182952.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Kadekawa,K., Nishijima,S., Noguchi,K., Matsumoto,S. and Sugaya,K.
  TITLE     Elucidation of the pathophysiology of interstitial cystitis/bladder
            pain syndrome via experimental autoimmune cystitis rat model
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 327 (2), R250-R260 (2024)
   PUBMED   38842512
REFERENCE   2  (bases 1 to 1054)
  AUTHORS   Hassan,A.O., Case,J.B., Winkler,E.S., Thackray,L.B., Kafai,N.M.,
            Bailey,A.L., McCune,B.T., Fox,J.M., Chen,R.E., Alsoussi,W.B.,
            Turner,J.S., Schmitz,A.J., Lei,T., Shrihari,S., Keeler,S.P.,
            Fremont,D.H., Greco,S., McCray,P.B. Jr., Perlman,S., Holtzman,M.J.,
            Ellebedy,A.H. and Diamond,M.S.
  TITLE     A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by
            Neutralizing Antibodies
  JOURNAL   Cell 182 (3), 744-753 (2020)
   PUBMED   32553273
REFERENCE   3  (bases 1 to 1054)
  AUTHORS   Fang,J.Z., Li,C., Liu,X.Y., Hu,T.T., Fan,Z.S. and Han,Z.G.
  TITLE     Hepatocyte-Specific Arid1a Deficiency Initiates Mouse
            Steatohepatitis and Hepatocellular Carcinoma
  JOURNAL   PLoS One 10 (11), e0143042 (2015)
   PUBMED   26569409
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1054)
  AUTHORS   Crawford,M.A., Burdick,M.D., Glomski,I.J., Boyer,A.E., Barr,J.R.,
            Mehrad,B., Strieter,R.M. and Hughes,M.A.
  TITLE     Interferon-inducible CXC chemokines directly contribute to host
            defense against inhalational anthrax in a murine model of infection
  JOURNAL   PLoS Pathog 6 (11), e1001199 (2010)
   PUBMED   21124994
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1054)
  AUTHORS   Kelsen,S.G., Aksoy,M.O., Georgy,M., Hershman,R., Ji,R., Li,X.,
            Hurford,M., Solomides,C., Chatila,W. and Kim,V.
  TITLE     Lymphoid follicle cells in chronic obstructive pulmonary disease
            overexpress the chemokine receptor CXCR3
  JOURNAL   Am J Respir Crit Care Med 179 (9), 799-805 (2009)
   PUBMED   19218194
REFERENCE   6  (bases 1 to 1054)
  AUTHORS   McColl,S.R., Mahalingam,S., Staykova,M., Tylaska,L.A., Fisher,K.E.,
            Strick,C.A., Gladue,R.P., Neote,K.S. and Willenborg,D.O.
  TITLE     Expression of rat I-TAC/CXCL11/SCYA11 during central nervous system
            inflammation: comparison with other CXCR3 ligands
  JOURNAL   Lab Invest 84 (11), 1418-1429 (2004)
   PUBMED   15322564
REFERENCE   7  (bases 1 to 1054)
  AUTHORS   Nance,S., Cross,R. and Fitzpatrick,E.
  TITLE     Chemokine production during hypersensitivity pneumonitis
  JOURNAL   Eur J Immunol 34 (3), 677-685 (2004)
   PUBMED   14991597
REFERENCE   8  (bases 1 to 1054)
  AUTHORS   Yang,D., Chen,Q., Hoover,D.M., Staley,P., Tucker,K.D., Lubkowski,J.
            and Oppenheim,J.J.
  TITLE     Many chemokines including CCL20/MIP-3alpha display antimicrobial
            activity
  JOURNAL   J Leukoc Biol 74 (3), 448-455 (2003)
   PUBMED   12949249
REFERENCE   9  (bases 1 to 1054)
  AUTHORS   Lasagni,L., Francalanci,M., Annunziato,F., Lazzeri,E., Giannini,S.,
            Cosmi,L., Sagrinati,C., Mazzinghi,B., Orlando,C., Maggi,E.,
            Marra,F., Romagnani,S., Serio,M. and Romagnani,P.
  TITLE     An alternatively spliced variant of CXCR3 mediates the inhibition
            of endothelial cell growth induced by IP-10, Mig, and I-TAC, and
            acts as functional receptor for platelet factor 4
  JOURNAL   J Exp Med 197 (11), 1537-1549 (2003)
   PUBMED   12782716
REFERENCE   10 (bases 1 to 1054)
  AUTHORS   Belperio,J.A., Keane,M.P., Burdick,M.D., Lynch,J.P. 3rd, Xue,Y.Y.,
            Li,K., Ross,D.J. and Strieter,R.M.
  TITLE     Critical role for CXCR3 chemokine biology in the pathogenesis of
            bronchiolitis obliterans syndrome
  JOURNAL   J Immunol 169 (2), 1037-1049 (2002)
   PUBMED   12097412
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF537209.1.
            
            On Oct 17, 2004 this sequence version replaced NM_182952.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF537209.1, BC168725.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="LEW"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p22"
     gene            1..1054
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /note="C-X-C motif chemokine ligand 11"
                     /db_xref="GeneID:305236"
                     /db_xref="RGD:727827"
     exon            1..122
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..364
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /note="C-X-C motif chemokine 11; chemokine (C-X-C motif)
                     ligand 11"
                     /codon_start=1
                     /product="C-X-C motif chemokine 11 precursor"
                     /protein_id="NP_891997.1"
                     /db_xref="GeneID:305236"
                     /db_xref="RGD:727827"
                     /translation="MNRTGMAVALAMIIWATTVPGFVMFKGGRCLCIDRGVKVVKMAA
                     IKEVSVIYPSNGCDKVEVIVTLKAHKGQRCLDPTSKQARLIMQTIQKKNFLRRQNM"
     exon            123..249
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /inference="alignment:Splign:2.1.0"
     exon            250..322
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /inference="alignment:Splign:2.1.0"
     exon            323..1054
                     /gene="Cxcl11"
                     /gene_synonym="SCYB11"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgctgctctc tgcgaagaaa gatcaccaga gccacagcag agagctgcag ctgccgctga
       61 gatgaacagg acgggcatgg ccgtagccct ggctatgatc atctgggcca caacggttcc
      121 aggcttcgtt atgttcaaag gggggcgctg tctttgcatc gaccgcggag tgaaagtggt
      181 caaaatggca gcaatcaagg aagtttctgt aatttacccg agtaacggct gtgacaaagt
      241 tgaagtgatt gttaccctga aggctcataa aggacaaagg tgcctggacc ccacatccaa
      301 gcaagctcgc ctcataatgc agacaataca aaaaaagaat tttttaaggc gccagaacat
      361 gtgatgggcc ctcaaattcg agctctgtgc caagaagctg accctctcct gtcttggaat
      421 atgcatccgt tttgccagat tgcagaactc gctaggaggt cggatacctc taaactattc
      481 tgcttggcta tgaaaatatt tatctcgaag agtcatgtgt ctctgtgtgt gcacactccg
      541 agttatcgtc tatggttaca atggacacat tgttactgga atcccgcccg cccgctggtt
      601 ggattcagaa gcatctagtg tagaaaaaca ttactcaagg aatttttcat ggaaataaca
      661 tccctttccc caaataacac gaggcacatg aacatctagg aagaagattc cacatatcat
      721 cttgcttgta catttaaaaa gatttagcat tcatgaggtg ccctgcaaac atttctacgc
      781 tgtagaaacg agtaagagaa cactactgtt tcctgagtta atcacactgg cttcccactg
      841 aggcagtcta aagggctaaa gatgtgtatt tcctgtacat ctggctttat ctgttttatc
      901 agtgacaata atctggatag atttttaaaa taaattgctt ttgctcacca aagaaaatgt
      961 tggaaaaaaa atctattcat ctctttgagt ctgttttcca ttattctgcc tttgaaaaaa
     1021 atatgtaaat gtgtacttgg tcctttcctt tgtc
//
