LOCUS       NM_001024987            1376 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus CWC15 spliceosome-associated protein (Cwc15),
            mRNA.
ACCESSION   NM_001024987 XM_217080
VERSION     NM_001024987.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1376)
  AUTHORS   Bertram,K., Agafonov,D.E., Liu,W.T., Dybkov,O., Will,C.L.,
            Hartmuth,K., Urlaub,H., Kastner,B., Stark,H. and Luhrmann,R.
  TITLE     Cryo-EM structure of a human spliceosome activated for step 2 of
            splicing
  JOURNAL   Nature 542 (7641), 318-323 (2017)
   PUBMED   28076346
REFERENCE   2  (bases 1 to 1376)
  AUTHORS   Chanarat,S. and Strasser,K.
  TITLE     Splicing and beyond: the many faces of the Prp19 complex
  JOURNAL   Biochim Biophys Acta 1833 (10), 2126-2134 (2013)
   PUBMED   23742842
  REMARK    Review article
REFERENCE   3  (bases 1 to 1376)
  AUTHORS   Grote,M., Wolf,E., Will,C.L., Lemm,I., Agafonov,D.E., Schomburg,A.,
            Fischle,W., Urlaub,H. and Luhrmann,R.
  TITLE     Molecular architecture of the human Prp19/CDC5L complex
  JOURNAL   Mol Cell Biol 30 (9), 2105-2119 (2010)
   PUBMED   20176811
REFERENCE   4  (bases 1 to 1376)
  AUTHORS   Jurica,M.S., Licklider,L.J., Gygi,S.R., Grigorieff,N. and
            Moore,M.J.
  TITLE     Purification and characterization of native spliceosomes suitable
            for three-dimensional structural analysis
  JOURNAL   RNA 8 (4), 426-439 (2002)
   PUBMED   11991638
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC091396.1.
            
            On Jun 25, 2005 this sequence version replaced XM_217080.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091396.1, FM074559.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1376
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q12"
     gene            1..1376
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /note="CWC15 spliceosome-associated protein"
                     /db_xref="GeneID:300361"
                     /db_xref="RGD:1310669"
     exon            1..122
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     exon            123..256
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     CDS             126..815
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /note="protein CWC15 homolog; CWC15 spliceosome-associated
                     protein homolog"
                     /codon_start=1
                     /product="spliceosome-associated protein CWC15 homolog"
                     /protein_id="NP_001020158.1"
                     /db_xref="GeneID:300361"
                     /db_xref="RGD:1310669"
                     /translation="MTTAARPTFEPARGGRGKGEGDLSQLSKQYSSRDLPSHTKIKYR
                     QTTQDAPEEVRNRDFRRELEERERAAAREKNRDRPTREHTTSSSVSKKPRLDQIPAAN
                     LDADDPLTDEEDEDFEEESDDDDTAALLAELEKIKKERAEEQARKEQEQKAEEERIRM
                     ENILSGNPLLNLTGPSQPQANFKVKRRWDDDVVFKNCAKGIDDQKKDKRFVNDTLRSE
                     FHKKFMEKYIK"
     exon            257..369
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     exon            370..458
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     exon            459..566
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     exon            567..685
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
     exon            686..1349
                     /gene="Cwc15"
                     /gene_synonym="RGD1310669"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggtgtaga gactggaagt tctgcatttt gcttccggtt ttgcgcagag atttctggga
       61 gttaagggtc gcaatggttc gtgagtgagc ttctgaaggc actgcgtcga acccccgcca
      121 caaagatgac aacagcagcc aggccaactt ttgaacctgc aagaggtggg agaggaaaag
      181 gagaaggtga tttgagccag ctctccaagc agtattcaag cagagacctt ccctctcata
      241 caaagataaa gtacagacaa accacacagg atgcccctga agaggttcgc aaccgtgact
      301 tcaggagaga gttggaagag agggagagag ctgctgcaag ggagaaaaat agggaccgtc
      361 caacccgaga acacacaact tcctcttcgg tgtccaagaa gccccgctta gaccagattc
      421 ctgctgccaa ccttgatgct gacgatcctc tcacagatga ggaagatgag gattttgaag
      481 aggaaagcga tgacgatgac actgcagctc ttcttgcaga gctagaaaag atcaagaagg
      541 agagagctga agagcaggcc agaaaggagc aagaacaaaa agcagaggaa gagagaattc
      601 gcatggaaaa cattctgagt ggaaaccctc tcctgaatct cacgggcccg tcccagcctc
      661 aggccaactt caaggttaaa agaaggtggg acgatgatgt tgtttttaag aactgtgcaa
      721 agggtataga tgatcaaaag aaagacaaaa gatttgtaaa cgatacgctg cgatctgaat
      781 ttcacaaaaa gttcatggag aaatatatca agtagtacag ttttatgtgc ttaattaaag
      841 actaaagtgt ccaggatcca tttgatgttt ggttttgttc tttcccagct ctgactttct
      901 caatcccttc cctaagtgtc gtactttact ggataatggg tttagaaatg ggttgagggc
      961 tggagagatg gcttagcggt taagagcacc cgactgctct tccagaggtc atgagttcaa
     1021 ttcccagcaa ccacatggtg gctcacaacc atctgtaaag agatccgatg ccctcttctg
     1081 gtgtatctga agacagctac agtgtactca tatataataa ataataaatc tttaaaaaaa
     1141 aaaaagaaag aaatgggttg aaccaggcct tagtttcttt ttaatatggg gaaaggggaa
     1201 atctgcttgt gataaatatt tttaacctaa atcattgtcc ccaacttttt gctataattt
     1261 atacagctta taaaaagttg cataactctt ttcaaaatga aaattatctt tgtgtgctgt
     1321 gtttttaata cattaagttt tctcctttaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//
