LOCUS       NM_001399691            1298 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus cutC copper transporter (Cutc), transcript
            variant 1, mRNA.
ACCESSION   NM_001399691 XM_006231526
VERSION     NM_001399691.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1298)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   2  (bases 1 to 1298)
  AUTHORS   Li,Y., Du,J., Zhang,P. and Ding,J.
  TITLE     Crystal structure of human copper homeostasis protein CutC reveals
            a potential copper-binding site
  JOURNAL   J Struct Biol 169 (3), 399-405 (2010)
   PUBMED   19878721
REFERENCE   3  (bases 1 to 1298)
  AUTHORS   Li,J., Ji,C., Chen,J., Yang,Z., Wang,Y., Fei,X., Zheng,M., Gu,X.,
            Wen,G., Xie,Y. and Mao,Y.
  TITLE     Identification and characterization of a novel Cut family cDNA that
            encodes human copper transporter protein CutC
  JOURNAL   Biochem Biophys Res Commun 337 (1), 179-183 (2005)
   PUBMED   16182249
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 12, 2022 this sequence version replaced XM_006231526.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360186.2944394.1,
                                           SRR26360190.1448444.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000001.1  252571521-252571708
            189-260             JAXUCZ010000001.1  252574010-252574081
            261-320             JAXUCZ010000001.1  252576416-252576475
            321-530             JAXUCZ010000001.1  252577343-252577552
            531-566             JAXUCZ010000001.1  252578213-252578248
            567-700             JAXUCZ010000001.1  252580785-252580918
            701-728             JAXUCZ010000001.1  252582491-252582518
            729-834             JAXUCZ010000001.1  252584845-252584950
            835-1298            JAXUCZ010000001.1  252585806-252586269
FEATURES             Location/Qualifiers
     source          1..1298
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1298
                     /gene="Cutc"
                     /note="cutC copper transporter"
                     /db_xref="GeneID:361760"
                     /db_xref="RGD:1304966"
     exon            1..188
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     CDS             131..949
                     /gene="Cutc"
                     /note="isoform 1 is encoded by transcript variant 1;
                     copper homeostasis protein cutC homolog; cutC copper
                     transporter homolog"
                     /codon_start=1
                     /product="copper homeostasis protein cutC homolog isoform
                     1"
                     /protein_id="NP_001386620.1"
                     /db_xref="GeneID:361760"
                     /db_xref="RGD:1304966"
                     /translation="MKKGISCERKQAWISSGKAGAGNGFLMEVCVDSVESAVNAERGG
                     ADRIELCSGLLEGGTTPSMGVLQVVKQSVQIPVFVMIRPRGGDFLYSDREVEVMKADI
                     RLAKLYGADGLVFGALTEDGHIDQELCLSLVALCRPLPVTFHRAFDMVQDPMAALETL
                     LTLGFERVLTSGCDSSALEGLPLIKQLTDQAKGRIVVMPGGGITVKNLQRILEGSGAT
                     EFHCSARSSRDSGMKFRNSSVAMGASLAHSEYSLKVTDVTKVRTLNAIAKDVLV"
     exon            189..260
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            261..320
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            321..530
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            531..566
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            567..700
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            701..728
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            729..834
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
     exon            835..1298
                     /gene="Cutc"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 actgcgcttg cgcatatgac tccgcggggg ctgcggggca ccggcatcgg ggccgcgcct
       61 tctcggtggc tcgcgcagcc gcggggactc agtggaaacc gaaggcgagc gaggaaggaa
      121 cgcgggaagc atgaagaaag ggatttcttg cgagcggaaa caggcgtgga tatcgtcggg
      181 gaaggcggga gcaggaaatg gatttcttat ggaagtgtgc gtagattcgg tggagtcggc
      241 tgtgaatgca gaaagaggag gtgctgaccg gattgaatta tgttctggtt tactggaggg
      301 aggaaccaca cccagcatgg gtgttcttca agtagtaaag cagagtgttc agatcccagt
      361 ttttgtgatg attcgaccac gtggaggtga ttttctatat tcagatcgtg aagttgaggt
      421 gatgaaggct gacattcgtc ttgccaagct ttatggtgct gatggtttgg tatttggggc
      481 attgactgaa gatggacaca ttgaccaaga gctatgcttg tctcttgtag ctctctgccg
      541 tcctctacca gtcactttcc acagagcctt tgatatggtt caagatccaa tggcagctct
      601 ggagaccctc ctgaccttgg ggtttgaacg cgttctgacc agtgggtgtg acagttcagc
      661 actggaagga ctgcctctca taaagcagct cacagaccag gcaaaaggca ggattgtggt
      721 aatgccagga ggtgggataa cagttaaaaa tctgcaaagg atccttgagg gttctggagc
      781 tacagaattc cactgttctg cccgatcttc tagagactca ggaatgaagt ttcgaaattc
      841 ctctgttgca atgggagctt cacttgctca ttcagaatat tctctaaagg taacagatgt
      901 gacaaaagta aggactttga atgctattgc aaaggatgtc ctagtttagt taaacttgtc
      961 tgagagacat gggtatcgca gtgtgaaaga agcagttgga tcgacaatct ctatgacagc
     1021 accaaccttc cacatggccg tgggtgtttc taagaagaaa aagacatcgg acagcaatgt
     1081 gatcactttc tttggtagtc attgctgtct gccatcatgg gtgaatttag tctgtgcttc
     1141 ttccacaagg gcaggcttag ctttcagtgg gcttaactaa tgaactggca gtgttcagct
     1201 gcaaggcatg aaaccagagt ctgcttcagg gttgatttag tgccactttt gtgccttttt
     1261 gttttgtaaa ataaaaattc tccttctgtt gtgtttta
//
